BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2163.p (227 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ZbioD [H] COG0132 Dethiobiotin synthetase EcZ Escherichia coli O... 171 1e-42 ECs0856 [H] COG0132 Dethiobiotin synthetase Ecs Escherichia coli... 171 1e-42 YPO1154 [H] COG0132 Dethiobiotin synthetase Ype Yersinia pestis 171 1e-42 bioD [H] COG0132 Dethiobiotin synthetase Eco Escherichia coli K12 168 1e-41 XF2477 [H] COG0132 Dethiobiotin synthetase Xfa Xylella fastidios... 164 1e-40 >ZbioD [H] COG0132 Dethiobiotin synthetase EcZ Escherichia coli O157:H7 EDL933 Length = 225 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/205 (46%), Positives = 123/205 (60%), Gaps = 1/205 (0%) Query: 4 RSYFVTGTDTGVGKTLVASALVHLHAARGVRAAGMKPVASGAFLHPDGQWCNDDVQALQA 63 + YFVTGTDT VGKT+ + AL+ A G R AG KPVASG+ P+G N D ALQ Sbjct: 3 KRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEG-LRNSDALALQR 61 Query: 64 AASVALPPHLVNPYLLRQATAPHIAARAEGVRIELEHLVQCHAQLLALCDVLIVEGAGGF 123 +S+ L VNPY + T+PHI + EG IE + L D ++VEGAGG+ Sbjct: 62 NSSLQLDYATVNPYTFAEPTSPHIISAQEGRSIESSVMSSGLRALEQQADWVLVEGAGGW 121 Query: 124 MVPLDERYHSDDLVARLDLPVVLVVGIRLGCINHALLTQQAIRWRGLRLAGWVANRIDAE 183 PL + + D V + LPV+LVVG++LGCINHA+LT QAI+ GL LAGWVAN + Sbjct: 122 FTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPP 181 Query: 184 EDQADAMIDTLVQRLQAPLLGRLPW 208 + + TL + + APLLG PW Sbjct: 182 GKRHAEYMTTLTRMIPAPLLGESPW 206 >ECs0856 [H] COG0132 Dethiobiotin synthetase Ecs Escherichia coli O157:H7 Length = 225 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 95/205 (46%), Positives = 123/205 (60%), Gaps = 1/205 (0%) Query: 4 RSYFVTGTDTGVGKTLVASALVHLHAARGVRAAGMKPVASGAFLHPDGQWCNDDVQALQA 63 + YFVTGTDT VGKT+ + AL+ A G R AG KPVASG+ P+G N D ALQ Sbjct: 3 KRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEG-LRNSDALALQR 61 Query: 64 AASVALPPHLVNPYLLRQATAPHIAARAEGVRIELEHLVQCHAQLLALCDVLIVEGAGGF 123 +S+ L VNPY + T+PHI + EG IE + L D ++VEGAGG+ Sbjct: 62 NSSLQLDYATVNPYTFAEPTSPHIISAQEGRSIESSVMSSGLRALEQQADWVLVEGAGGW 121 Query: 124 MVPLDERYHSDDLVARLDLPVVLVVGIRLGCINHALLTQQAIRWRGLRLAGWVANRIDAE 183 PL + + D V + LPV+LVVG++LGCINHA+LT QAI+ GL LAGWVAN + Sbjct: 122 FTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQAIQHAGLTLAGWVANDVTPP 181 Query: 184 EDQADAMIDTLVQRLQAPLLGRLPW 208 + + TL + + APLLG PW Sbjct: 182 GKRHAEYMTTLTRMIPAPLLGESPW 206 >YPO1154 [H] COG0132 Dethiobiotin synthetase Ype Yersinia pestis Length = 240 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 99/208 (47%), Positives = 130/208 (62%), Gaps = 2/208 (0%) Query: 1 MTGRSYFVTGTDTGVGKTLVASALVHLHAARGVRAAGMKPVASGAFLHPDGQWCNDDVQA 60 MT R +F+TGTDT VGKT+ + AL+ A+G R AG KPVASG+ + DG N D A Sbjct: 1 MTKR-WFITGTDTDVGKTVASCALLQAATAQGYRTAGYKPVASGSQMTADG-LRNSDALA 58 Query: 61 LQAAASVALPPHLVNPYLLRQATAPHIAARAEGVRIELEHLVQCHAQLLALCDVLIVEGA 120 LQA +S L VNP+ +AT+PHIA+ +EG I L L Q QL D +++EGA Sbjct: 59 LQANSSQRLGYSQVNPFTFLEATSPHIASESEGRAIPLTALSQGLRQLEPSADWILIEGA 118 Query: 121 GGFMVPLDERYHSDDLVARLDLPVVLVVGIRLGCINHALLTQQAIRWRGLRLAGWVANRI 180 GG+ PL + D V + LPV++VVG++LGCINHALLT QAI+ GL LAGWVAN + Sbjct: 119 GGWFTPLSPQATFADWVQQEQLPVIMVVGVKLGCINHALLTAQAIQHAGLTLAGWVANEV 178 Query: 181 DAEEDQADAMIDTLVQRLQAPLLGRLPW 208 + TL + + APLLG +P+ Sbjct: 179 TPAGRRQAEYQATLTRMITAPLLGIIPY 206 >bioD [H] COG0132 Dethiobiotin synthetase Eco Escherichia coli K12 Length = 225 Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 94/205 (45%), Positives = 123/205 (60%), Gaps = 1/205 (0%) Query: 4 RSYFVTGTDTGVGKTLVASALVHLHAARGVRAAGMKPVASGAFLHPDGQWCNDDVQALQA 63 + YFVTGTDT VGKT+ + AL+ A G R AG KPVASG+ P+G N D ALQ Sbjct: 3 KRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGSEKTPEG-LRNSDALALQR 61 Query: 64 AASVALPPHLVNPYLLRQATAPHIAARAEGVRIELEHLVQCHAQLLALCDVLIVEGAGGF 123 +S+ L VNPY + T+PHI + EG IE + L D ++VEGAGG+ Sbjct: 62 NSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAGLRALEQQADWVLVEGAGGW 121 Query: 124 MVPLDERYHSDDLVARLDLPVVLVVGIRLGCINHALLTQQAIRWRGLRLAGWVANRIDAE 183 PL + + D V + LPV+LVVG++LGCINHA+LT Q I+ GL LAGWVAN + Sbjct: 122 FTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTAQVIQHAGLTLAGWVANDVTPP 181 Query: 184 EDQADAMIDTLVQRLQAPLLGRLPW 208 + + TL + + APLLG +PW Sbjct: 182 GKRHAEYMTTLTRMIPAPLLGEIPW 206 >XF2477 [H] COG0132 Dethiobiotin synthetase Xfa Xylella fastidiosa 9a5c Length = 226 Score = 164 bits (416), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 107/222 (48%), Positives = 134/222 (60%), Gaps = 2/222 (0%) Query: 1 MTGRSYFVTGTDTGVGKTLVASALVHLHAARGVRAAGMKPVASGAFLHPDGQWCNDDVQA 60 M+ +++VTGTDTG+GKT V+ L+H+ RG RA GMKPVASG + D W N+D A Sbjct: 1 MSLSAFYVTGTDTGIGKTFVSCILLHMLRGRGQRAVGMKPVASGC-TYSDTGWRNEDALA 59 Query: 61 LQAAASVALPPHLVNPYLLRQATAPHIAARAEGVRIELEHLVQCHAQLLALCDVLIVEGA 120 LQAA+ L+NPY L A AP IAA GV + LE L QL A DV++VEG Sbjct: 60 LQAASDPTPAYDLINPYALPAAVAPEIAAIEAGVTVALEPLSAAFTQLRAQADVVVVEGV 119 Query: 121 GGFMVPLDERYHSDDLVARLDLPVVLVVGIRLGCINHALLTQQAIRWRGLRLAGWVANRI 180 GG+ PL+ LV L++PVVLVVG+RLGC+NHA L+ AI GLR GW+AN I Sbjct: 120 GGWATPLNATIDQATLVRALEIPVVLVVGLRLGCLNHARLSTTAIMADGLRCIGWIANTI 179 Query: 181 DAEEDQADAMIDTLVQRLQAPLLGRLP-WAPGMTAAQAAARL 221 D + + + L QRL P G LP PG+ A AARL Sbjct: 180 DPHMARIEENLALLRQRLPIPYWGHLPHIPPGINPATLAARL 221