BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2096.p (499 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1748 [S] COG0397 Uncharacterized conserved protein Rso Ralsto... 563 e-160 VC1931 [S] COG0397 Uncharacterized conserved protein Vch Vibrio ... 442 e-124 PA5023 [S] COG0397 Uncharacterized conserved protein Pae Pseudom... 440 e-123 ydiU [S] COG0397 Uncharacterized conserved protein Eco Escherich... 438 e-122 Z2735 [S] COG0397 Uncharacterized conserved protein EcZ Escheric... 432 e-121 >RSc1748 [S] COG0397 Uncharacterized conserved protein Rso Ralstonia solanacearum Length = 525 Score = 563 bits (1452), Expect = e-160, Method: Compositional matrix adjust. Identities = 300/517 (58%), Positives = 353/517 (68%), Gaps = 28/517 (5%) Query: 9 DSLSYPL-----PPFGNRFADLPPAFYTRLQPTPLPA-PYLVGFSDAAAASVGLARPAEE 62 DSL+ P P FA L F TRL P P+PA PYLVGFS AAA +GL+R + Sbjct: 11 DSLASPFDWPGRPHAAPGFARLGERFLTRLPPVPMPAAPYLVGFSPEAAAPLGLSRAGLD 70 Query: 63 DRSFLDIFAGNQIAPGSMPLSAVYSGHQFGVWAGQLGDGRAITLGDLAATDGQGRIELQL 122 + LD+F GN IA S PL+ VYSGHQFGVWAGQLGDGRA+ L +L DG E+QL Sbjct: 71 TPAGLDVFVGNAIAAWSDPLATVYSGHQFGVWAGQLGDGRALLLAELQTADGP--CEVQL 128 Query: 123 KGAGLTPYSRMGDGRAVLRSSIREFLCSEAMAALGIPTTRALTVIGSDQRVLRESAETAA 182 KGAGLTPYSRMGDGRAVLRSSIREFLCSEAMA LGIPTTRAL VIG+D V RE+ ETAA Sbjct: 129 KGAGLTPYSRMGDGRAVLRSSIREFLCSEAMAGLGIPTTRALCVIGADAPVRRETIETAA 188 Query: 183 VVTRMAPSFIRFGSFEHWYYNQRFDELKVLGDTVLEQFYPALLQEDNPYQALLQEVTRRT 242 VVTR+APSF+RFG FEH+ N++ EL+ L D V+++FYPA E PY ALL+EV RRT Sbjct: 189 VVTRLAPSFVRFGHFEHFAANEKLPELRALADFVIDRFYPACRAEPQPYLALLREVGRRT 248 Query: 243 ATLMAQWQAVGFMHGVMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDGQGRYSYQMQ 302 A L+AQWQAVGF HGVMNTDNMSILGLTLDYGPFGF++ FDA HICNH+D GRY+Y Q Sbjct: 249 AALIAQWQAVGFCHGVMNTDNMSILGLTLDYGPFGFLDGFDANHICNHSDTGGRYAYAQQ 308 Query: 303 PRIGQWNCFALGQAMLPLIGS-----------------VEQTEAALAGYEAVFQAQHDAL 345 P+I WN F L QA+LPL GS ++ + AL Y + A Sbjct: 309 PQIAYWNLFCLAQALLPLCGSDPTAFTDLSDEAQAQPAIDAAQEALLVYRDTYGEAFYAR 368 Query: 346 LRAKLGLRTQQADDARLIEALFAILQANHVDFTLFFRRLGDLQISNT---ANDEALRDLI 402 RAKLGL D L LF +L D+TLFFR L D++ +T A +RD+ Sbjct: 369 YRAKLGLTQAHDGDEALFGDLFKLLHTQRADYTLFFRHLADVRRDDTPAQAQARTVRDVF 428 Query: 403 LDRPAFDAWAAQYRARLRAEDSDDAARRLAMHQVNPKYVLRNYLAQIAIERAQHKDFSEV 462 DR + DAW A YR RL+ E + DAAR AM +VNPKYVLRN+LA+IAI RA KDFSEV Sbjct: 429 FDRDSADAWLAAYRQRLQTEPAPDAARAEAMRRVNPKYVLRNHLAEIAIRRAGEKDFSEV 488 Query: 463 ARLQAILSRPFDEQPEFDQYADLPPDWASHLEVSCSS 499 L+A+L+RPFD+ P F+ YA PDWA+ LEVSCSS Sbjct: 489 ENLRAVLARPFDDHPGFEHYAGPAPDWAASLEVSCSS 525 >VC1931 [S] COG0397 Uncharacterized conserved protein Vch Vibrio cholerae Length = 508 Score = 442 bits (1138), Expect = e-124, Method: Compositional matrix adjust. Identities = 244/505 (48%), Positives = 306/505 (60%), Gaps = 16/505 (3%) Query: 4 SSPLIDSLSYPL---PPFGNRFADLPPAFYTRLQPTPLPAPYLVGFSDAAAASVGLARPA 60 S PLI SL + RFA LP AFYT + P PL ++ A GL A Sbjct: 11 SKPLIASLVMSVWNAVHLSRRFAALPQAFYTPVHPQPLQNVRWGMWNSRLAQQFGLPE-A 69 Query: 61 EEDRSFLDIFAGNQIAPGSMPLSAVYSGHQFGVWAGQLGDGRAITLGDLAATDGQGRIEL 120 D L + A S P++ Y+GHQFGV+ LGDGR + L ++A G+ ++ Sbjct: 70 PNDELLLSLSGQQLPADFS-PVAMKYAGHQFGVYNPDLGDGRGLLLAEMATKQGE-VFDI 127 Query: 121 QLKGAGLTPYSRMGDGRAVLRSSIREFLCSEAMAALGIPTTRALTVIGSDQRVLRESAET 180 LKGAGLTPYSRMGDGRAVLRSS+RE+LCSEAMA LGI TTRAL ++ S+ V RE E Sbjct: 128 HLKGAGLTPYSRMGDGRAVLRSSLREYLCSEAMAGLGIATTRALALMSSETPVYREREER 187 Query: 181 AAVVTRMAPSFIRFGSFEHWYYNQRFDELKVLGDTVLEQFYPALLQEDNPYQALLQEVTR 240 A++ R+A + +RFG FEH++Y + LK+L D V+E +P +Q PY A +V Sbjct: 188 GALLVRLAHTHVRFGHFEHFFYTDQHANLKLLADKVIEWHFPDCVQTSKPYAAWFSQVVE 247 Query: 241 RTATLMAQWQAVGFMHGVMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDGQGRYSYQ 300 RTA ++AQWQA GF HGVMNTDNMSILG T DYGPF F++ +D ICNH+D QGRY++ Sbjct: 248 RTALMIAQWQAYGFNHGVMNTDNMSILGETFDYGPFAFLDDYDPNFICNHSDYQGRYAFD 307 Query: 301 MQPRIGQWNCFALGQAMLPLIGSVEQTEAALAGYEAVFQAQHDALLRAKLGLRTQQADDA 360 QPRIG WN AL A+ PLI + EAAL Y L+RAKLGL TQQ D Sbjct: 308 QQPRIGLWNLSALAHALSPLIDK-DDLEAALGSYSERLNLHFSRLMRAKLGLATQQEGDG 366 Query: 361 RLIEALFAILQANHVDFTLFFRRLGDLQISNTANDEALRDLILDRPAFDAWAAQYRARLR 420 L FA+L NH D+T F R L L + +EA+ DL+LDR A W +Y R Sbjct: 367 ELFADFFALLANNHTDYTRFLRELSCL---DRQGNEAVIDLVLDREAAKTWLTRYLERAA 423 Query: 421 AEDSDDA------ARRLAMHQVNPKYVLRNYLAQIAIERAQHKDFSEVARLQAILSRPFD 474 E + R AM QVNPKY+LRNYLAQ AIE A+ DF E+ RL +L+ P+ Sbjct: 424 RELGQEGRPISTRERCQAMRQVNPKYILRNYLAQQAIEFAERGDFEEMQRLATVLASPYA 483 Query: 475 EQPEFDQYADLPPDWASHLEVSCSS 499 E PEF++YA LPP+W LE+SCSS Sbjct: 484 EHPEFERYAKLPPEWGKKLEISCSS 508 >PA5023 [S] COG0397 Uncharacterized conserved protein Pae Pseudomonas aeruginosa Length = 486 Score = 440 bits (1132), Expect = e-123, Method: Compositional matrix adjust. Identities = 241/482 (50%), Positives = 317/482 (65%), Gaps = 4/482 (0%) Query: 18 FGNRFADLPPAFYTRLQPTPLPAPYLVGFSDAAAASVGLARPAEEDRSFLDIFAGNQIAP 77 F NRFA L AF T + P P+ P LV S AA A + L ++ F ++F G+++ Sbjct: 9 FDNRFARLGGAFSTEVLPDPIAEPRLVVASPAALALLDLPAETSDEALFAELFGGHKLWS 68 Query: 78 GSMPLSAVYSGHQFGVWAGQLGDGRAITLGDLAATDGQGRIELQLKGAGLTPYSRMGDGR 137 + P + VYSGHQFG + +LGDGR + LG++ G+ +L LKGAG TPYSRMGDGR Sbjct: 69 EAEPRAMVYSGHQFGSYNPRLGDGRGLLLGEVINQAGE-HWDLHLKGAGQTPYSRMGDGR 127 Query: 138 AVLRSSIREFLCSEAMAALGIPTTRALTVIGSDQRVLRESAETAAVVTRMAPSFIRFGSF 197 AVLRSSIREFL SEA+ ALGIP++RAL VIGS V RE E+AA + R+APS +RFG F Sbjct: 128 AVLRSSIREFLASEALPALGIPSSRALCVIGSSTPVWREKKESAATLLRLAPSHVRFGHF 187 Query: 198 EHWYYNQRFDELKVLGDTVLEQFYPALLQEDNPYQALLQEVTRRTATLMAQWQAVGFMHG 257 E++YY ++ D+LK L VLE + + PY A+ ++V R A L+A+WQA GF HG Sbjct: 188 EYFYYTRQHDQLKQLAAFVLEHHFADCNAAERPYAAMFRQVVERNAELIARWQAYGFCHG 247 Query: 258 VMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDGQGRYSYQMQPRIGQWNCFALGQAM 317 VMNTDNMSILG+T DYGP+ F++ FDA HICNH+D GRYS+ Q I WN AL QA+ Sbjct: 248 VMNTDNMSILGITFDYGPYAFLDDFDANHICNHSDDAGRYSFSNQVPIAHWNLAALAQAL 307 Query: 318 LPLIGSVEQTEAALAGYEAVFQAQHDALLRAKLGLRTQQADDARLIEALFAILQANHVDF 377 PL+ V++ A+L + ++QA + L+R +LGL +D L++ L +Q + VD+ Sbjct: 308 TPLV-EVDELRASLDLFLPLYQAHYLDLMRRRLGLGVAAENDHALVQELLQRMQGSAVDY 366 Query: 378 TLFFRRLGDLQISNTANDEALRDLILDRPAFDAWAAQYRARLRAEDSDDAARRLAMHQVN 437 +LFFRRLG+ +LRD +DR AFD WA YR R+ E D +RR MH VN Sbjct: 367 SLFFRRLGEETPERAL--ASLRDDFVDREAFDRWAEAYRRRVEEEGGDQESRRRRMHAVN 424 Query: 438 PKYVLRNYLAQIAIERAQHKDFSEVARLQAILSRPFDEQPEFDQYADLPPDWASHLEVSC 497 P YVLRNYLAQ AIE A+ D++EV L +LSRPF+EQP +++ PPDW HLE+SC Sbjct: 425 PLYVLRNYLAQQAIEAAEQGDYTEVRLLHQVLSRPFEEQPGMERFTRRPPDWGRHLEISC 484 Query: 498 SS 499 SS Sbjct: 485 SS 486 >ydiU [S] COG0397 Uncharacterized conserved protein Eco Escherichia coli K12 Length = 478 Score = 438 bits (1126), Expect = e-122, Method: Compositional matrix adjust. Identities = 227/482 (47%), Positives = 306/482 (63%), Gaps = 8/482 (1%) Query: 18 FGNRFADLPPAFYTRLQPTPLPAPYLVGFSDAAAASVGLARPAEEDRSFLDIFAGNQIAP 77 F R+ D P YT L PTPL L+ + A ++ + P+ ++ ++ G + P Sbjct: 5 FVTRWRDELPETYTALSPTPLNNARLIWHNTELANTLSI--PSSLFKNGAGVWGGEALLP 62 Query: 78 GSMPLSAVYSGHQFGVWAGQLGDGRAITLGDLAATDGQGRIELQLKGAGLTPYSRMGDGR 137 G PL+ VYSGHQFGVWAGQLGDGR I LG+ DG ++ LKGAGLTPYSRMGDGR Sbjct: 63 GMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTT-MDWHLKGAGLTPYSRMGDGR 121 Query: 138 AVLRSSIREFLCSEAMAALGIPTTRALTVIGSDQRVLRESAETAAVVTRMAPSFIRFGSF 197 AVLRS+IRE L SEAM LGIPTTRAL+++ SD V RE+AE A++ R+APS +RFG F Sbjct: 122 AVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETAEPGAMLMRVAPSHLRFGHF 181 Query: 198 EHWYYNQRFDELKVLGDTVLEQFYPALLQEDNPYQALLQEVTRRTATLMAQWQAVGFMHG 257 EH+YY + ++++ L D + ++ L +++ Y+ +V RTA+L+AQWQ VGF HG Sbjct: 182 EHFYYRRESEKVRQLADFAIRHYWSHLADDEDKYRLWFSDVVARTASLIAQWQTVGFAHG 241 Query: 258 VMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDGQGRYSYQMQPRIGQWNCFALGQAM 317 VMNTDNMS+LGLTLDYGPFGF++ ++ ICNH+D QGRYS+ QP + WN L Q + Sbjct: 242 VMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSDHQGRYSFDNQPAVALWNLQRLAQTL 301 Query: 318 LPLIGSVEQTEAALAGYEAVFQAQHDALLRAKLGLRTQQADDARLIEALFAILQANHVDF 377 P + +V+ AL Y+ V + +R KLG T+Q +D L+ LF+++ D+ Sbjct: 302 SPFV-AVDALNEALDSYQQVLLTHYGERMRQKLGFMTEQKEDNALLNELFSLMARERSDY 360 Query: 378 TLFFRRLGDLQISNTANDEALRDLILDRPAFDAWAAQYRARLRAEDSDDAARRLAMHQVN 437 T FR L + + A+ LRD +DR AFD W A+YR RL+ ++ D+ R+ M VN Sbjct: 361 TRTFRMLSLTEQHSAAS--PLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVN 418 Query: 438 PKYVLRNYLAQIAIERAQHKDFSEVARLQAILSRPFDEQPEFDQYADLPPDWASHLEVSC 497 P VLRN+LAQ AIE A+ D +E+ RL L PF ++ D Y PPDW LEVSC Sbjct: 419 PALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRD--DDYVSRPPDWGKRLEVSC 476 Query: 498 SS 499 SS Sbjct: 477 SS 478 >Z2735 [S] COG0397 Uncharacterized conserved protein EcZ Escherichia coli O157:H7 EDL933 Length = 478 Score = 432 bits (1112), Expect = e-121, Method: Compositional matrix adjust. Identities = 226/482 (46%), Positives = 303/482 (62%), Gaps = 8/482 (1%) Query: 18 FGNRFADLPPAFYTRLQPTPLPAPYLVGFSDAAAASVGLARPAEEDRSFLDIFAGNQIAP 77 F R+ D P YT L PTPL L+ + A ++ + P+ ++ ++ G + P Sbjct: 5 FITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSI--PSSLFKNGAGVWGGETLLP 62 Query: 78 GSMPLSAVYSGHQFGVWAGQLGDGRAITLGDLAATDGQGRIELQLKGAGLTPYSRMGDGR 137 G PL+ VYSGHQFGVWAGQLGDGR I LG+ DG ++ LKGAGLTPYSRMGDGR Sbjct: 63 GMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTT-MDWHLKGAGLTPYSRMGDGR 121 Query: 138 AVLRSSIREFLCSEAMAALGIPTTRALTVIGSDQRVLRESAETAAVVTRMAPSFIRFGSF 197 AVLRS+IRE L SEAM LGIPTTRAL+++ SD V RE+ E A++ R+APS +RFG F Sbjct: 122 AVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRETVEPGAMLMRVAPSHLRFGHF 181 Query: 198 EHWYYNQRFDELKVLGDTVLEQFYPALLQEDNPYQALLQEVTRRTATLMAQWQAVGFMHG 257 EH+YY + D+++ L D + ++ L +++ Y+ +V RTA+L+AQWQ VGF HG Sbjct: 182 EHFYYRREPDKVRQLADFAIRHYWSHLEDDEDKYRLWFNDVVARTASLIAQWQTVGFAHG 241 Query: 258 VMNTDNMSILGLTLDYGPFGFMEAFDARHICNHTDGQGRYSYQMQPRIGQWNCFALGQAM 317 VMNTDNMS+LGLTLDYGPFGF+ ++ ICNH+D QGRYS+ QP + W L Q + Sbjct: 242 VMNTDNMSLLGLTLDYGPFGFLNDYEPGFICNHSDHQGRYSFDNQPAVALWILQRLAQTL 301 Query: 318 LPLIGSVEQTEAALAGYEAVFQAQHDALLRAKLGLRTQQADDARLIEALFAILQANHVDF 377 P + +V+ AL Y+ V + +R KLG T+Q +D L+ LF+++ D+ Sbjct: 302 SPFV-AVDALNEALDSYQQVLLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDY 360 Query: 378 TLFFRRLGDLQISNTANDEALRDLILDRPAFDAWAAQYRARLRAEDSDDAARRLAMHQVN 437 T FR L + + A+ LRD +DR AFD W A+YR RL+ ++ D+ R+ M VN Sbjct: 361 TRTFRMLSLTEQHSAAS--PLRDEFIDRAAFDDWFARYRGRLQQDEVSDSERQQLMQSVN 418 Query: 438 PKYVLRNYLAQIAIERAQHKDFSEVARLQAILSRPFDEQPEFDQYADLPPDWASHLEVSC 497 P VLRN+LAQ AIE A+ D +E+ RL L PF ++ D Y PPDW LEVSC Sbjct: 419 PALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRD--DDYVSRPPDWGKRLEVSC 476 Query: 498 SS 499 SS Sbjct: 477 SS 478