BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2087.p (314 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0239 [GER] COG0697 Permeases of the drug/metabolite transporte... 181 2e-45 RSp0133 [GER] COG0697 Permeases of the drug/metabolite transport... 135 1e-31 mlr5160 [GER] COG0697 Permeases of the drug/metabolite transport... 135 2e-31 AGl1685 [GER] COG0697 Permeases of the drug/metabolite transport... 124 4e-28 BMEII0677 [GER] COG0697 Permeases of the drug/metabolite transpo... 108 2e-23 >PA0239 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 181 bits (458), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 108/300 (36%), Positives = 173/300 (57%), Gaps = 8/300 (2%) Query: 1 MSSAVLPHPRIAHSHKLGILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFF 60 M+++ P P + + GIL + + ++ + D K L+ Y +VM+ W RY ++ Sbjct: 1 MNASTSPLPASDQTLR-GILLICAAVFLFASHDGLSKFLS-GFYPIVMVVWARYLVHTLL 58 Query: 61 MAATLAPLYRRRHGRSILQSNRLGLQLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAP 120 M A P R+G ++++S R +QL R L+G++L F + L+ +PLAE TA+NF AP Sbjct: 59 MVAVFVP----RNGLAVIRSRRPLMQLARALCLIGTSLFFTTGLRYLPLAEATAVNFLAP 114 Query: 121 LIVLAISPWLLGERSYVSRWIAVLIGFSGMLIVIRPSGDIPPYGVALGLISALTQALLSI 180 L+V A+S LL E+ + +W+AVL GF G+L ++RP G + L SAL L + Sbjct: 115 LLVTALSVPLLKEKVSLGQWLAVLTGFIGVLFIVRPGGALFTPAALFPLGSALCFGLYQL 174 Query: 181 LNRKASQADNPMVTLFYGALVGSVASTLMVPFFWTSHTPSMVELAILVSTGITSTIGHFL 240 L R + +D+P + F + ++ +L+VPFFW TPS++ ++++ G GH L Sbjct: 175 LTRMLANSDSPTTSNFLAGIFNTLIMSLLVPFFW--QTPSLLHGLMMIALGGCGMGGHLL 232 Query: 241 QNTAYKHAEASVLTPFFYAQIISACGMGWLVFGQFPDSITVLGIAIICASGIGIAYIEHK 300 A++HA + L PF Y QII A +G LVFG PD+ +LGI +ICASG+ +A+ + Sbjct: 233 LTQAFRHAPPATLAPFSYGQIIFAGLLGLLVFGHVPDAWALLGILVICASGLVVAWRRGR 292 >RSp0133 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 316 Score = 135 bits (340), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 106/288 (36%), Positives = 151/288 (52%), Gaps = 10/288 (3%) Query: 18 GILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATLAPLYRRRHGRSI 77 GI FLI+ + ++ DT K +++ VVM W RY + ATL P GRS+ Sbjct: 29 GIAFLIAAVAFFAVFDTLTKYISIT-VPVVMALWFRYLFQMVATGATLLP----SRGRSL 83 Query: 78 LQSNRLGLQLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAISPWLLGERSYV 137 L++ R LQ+ RG LLL +L F L+ +P+ + TA+ PL+V ++ LGE+ Sbjct: 84 LRTRRPWLQVVRGLLLLLVSLFSFLSLRRMPVGDVTAIVMLTPLVVTFVAAVSLGEQVSA 143 Query: 138 SRWIAVLIGFSGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQADNPMVTLFY 197 +RWI + GF G L+VIRP G +G+ L L + A ++ + + D T FY Sbjct: 144 TRWIFMAGGFFGALMVIRPGGAAFDWGMLLPLGMVVANAAFQVVTSRLANVDEAGTTQFY 203 Query: 198 GALVGSVASTLMVPFFWTSHTPSMVELAILVSTGITSTIGHFLQNTAYKHAEASVLTPFF 257 VG++ T M+PF W + L IL+ GI S+ GH L AY A ++LTP+ Sbjct: 204 TGAVGALLLTCMLPFGWQALGGKWWWLLILI--GIVSSSGHALLIMAYTRAPVAMLTPYL 261 Query: 258 YAQIISACGMGWLVFGQFPDSITVLGIAIIC---ASGIGIAYIEHKRA 302 Y QI A GWLVF PD +V GIAII A+G +A E + A Sbjct: 262 YMQIGFAMIGGWLVFSHVPDGWSVAGIAIIAMCGAAGTWVAARERRMA 309 >mlr5160 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 313 Score = 135 bits (339), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 91/275 (33%), Positives = 146/275 (53%), Gaps = 11/275 (4%) Query: 29 LSLLDTAGKLLALAGYHVVMIAWMRYTINLFFMAATLAPLYRRRHGRSILQSNRLGL--Q 86 + LDT+ K L LAG +++AW+R+ +++ + L R R L+ + L Sbjct: 27 FTFLDTSSKYLVLAGVSALIVAWVRFAVHVVLVGTLL------RGWRDPLRFRPVNLPAH 80 Query: 87 LGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAISPWLLGERSYVSRWIAVLIG 146 + RG L GST+ L+ + LAE T++ F P+++ A++ LLGE + RW+A+L Sbjct: 81 VLRGVFLFGSTMCNILALRSLQLAETTSIYFFGPMVITALAGPLLGEWAGWRRWLAILAA 140 Query: 147 FSGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQADNPMVTLFYGALVGSVAS 206 F+G+LI+ RP + G L S L+ I+ R+ S + + + AL +V Sbjct: 141 FAGVLIITRPGVGVFGIGHLFALGSMLSNCFYVIMTRRMSSTETSESLILFSALAPTVLL 200 Query: 207 TLMVPF-FWTSHTPSMVELAILVSTGITSTIGHFLQNTAYKHAEASVLTPFFYAQIISAC 265 M+PF F H IL+ G+ +GH+L AY+ A + L P+ Y+Q++ Sbjct: 201 LPMLPFSFSLPHDGW--HWFILLMLGVFGGVGHWLLVQAYRLATTTALAPYPYSQMVWMV 258 Query: 266 GMGWLVFGQFPDSITVLGIAIICASGIGIAYIEHK 300 GW+VF QFPD T++G AII ASG+ I + EH+ Sbjct: 259 ISGWIVFKQFPDRWTLVGAAIIVASGLYIVHREHR 293 >AGl1685 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 124 bits (310), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 95/292 (32%), Positives = 151/292 (51%), Gaps = 17/292 (5%) Query: 14 SHKLGILFLISGLWTLSLLDTAGKLLALAGYHVVMIAWMRY---TINLFFMAATLAPLYR 70 S K G L+ + + D K L A Y V +A +RY + + MAA R Sbjct: 3 SAKTGFLYALVAFTIFAAQDGISKHLGSA-YPPVFVAMLRYWAFAVFVLLMAA------R 55 Query: 71 RRHG-RSILQSNRLGLQLGRGALLLGSTLIFFSVLK--IVPLAEGTAMNFCAPLIVLAIS 127 G R + +NR LQ+ RG LL + I FS+ +V LA ++ APLIV A+S Sbjct: 56 SAGGIRGAVMANRPWLQISRGVLL--AVQIVFSIFSFAVVGLAHSHSILASAPLIVAALS 113 Query: 128 PWLLGERSYVSRWIAVLIGFSGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQ 187 LLGE RW A+ +GF G+L++++P GD + + ++A AL S+L R S+ Sbjct: 114 MPLLGEHVGWRRWCAIFVGFIGVLVILKPDGDGFDNKLIITFVAAFMLALYSVLTRLGSK 173 Query: 188 ADNPMVTLFYGALVGSVASTLMVPFFWTSHTPSMVELAILVSTGITSTIGHFLQNTAYKH 247 +D+ M + FY + G+ A TL+ PF+W P + +++ IT GH+ A++ Sbjct: 174 SDSAMTSFFYTGVAGAAALTLVGPFYWVPLAPQ--DWGWMLALCITGMSGHYCLIKAFEL 231 Query: 248 AEASVLTPFFYAQIISACGMGWLVFGQFPDSITVLGIAIICASGIGIAYIEH 299 A+A+ + PF Y Q++ +G ++G+ S V G AI+ A+G+ + EH Sbjct: 232 ADAASVQPFSYYQLVLVSIIGVTIYGEVVTSNMVTGAAIVIAAGLFTIWREH 283 >BMEII0677 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bme Brucella melitensis Length = 309 Score = 108 bits (269), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 103/301 (34%), Positives = 151/301 (50%), Gaps = 19/301 (6%) Query: 13 HSHKLGILFLISGLWTLSLLDTAGKLLALAGYHVVMIA-WMRYTIN---LFFMAATLAPL 68 +H G+ F++ + L L+D GK LA+ A +MR+ + +FF+ + L Sbjct: 10 EAHVKGMGFMVLSVLMLPLMDAIGKWLAMMDDLPPATATFMRFFVQCWLMFFIILVVGGL 69 Query: 69 YRRRHGRSILQSNRLGLQLGRGALLLGSTLIFFSVLKIVPLAEGTAMNFCAPLIVLAISP 128 R++ S+ +G L RGAL+ L FF+ +K +PLA+ A+ F PLI+ S Sbjct: 70 ------RALATSHLMG-NLLRGALMGFGGLCFFTAVKYMPLADALAVFFAEPLILTLFSA 122 Query: 129 WLLGERSYVSRWIAVLIGFSGMLIVIRPSGDIPPYGVALGLISALTQALLSILNRKASQA 188 L E+ R+ AV IG G +IVI+PS +I L L +A+T A+ ILNRK Sbjct: 123 LFLKEKVGWRRFSAVGIGLIGTMIVIQPSFEIFGMVSLLPLATAVTFAIYLILNRKYGAK 182 Query: 189 DNPMVTLFYGALVG----SVASTLMVPF-FWTSH--TPSMVE-LAILVSTGITSTIGHFL 240 ++P+ Y L G VA L F H P V+ +L+ G T+ H + Sbjct: 183 ESPLTMQLYAGLGGWLFVGVAMLLAADRSFDDMHFALPHSVQPWLLLLLLGTIGTVSHLI 242 Query: 241 QNTAYKHAEASVLTPFFYAQIISACGMGWLVFGQFPDSITVLGIAIICASGIGIAYIEHK 300 A K A AS+L PF Y +I++A MG ++FG FP LGIAII SG + E K Sbjct: 243 VVQASKLAPASMLAPFQYLEIVNAVLMGLIIFGDFPTPSKWLGIAIIIGSGFYVFMRESK 302 Query: 301 R 301 + Sbjct: 303 K 303