BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2077.p (553 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0547 [GEPR] COG0477 Permeases of the major facilitator superf... 766 0.0 PA3709 [GEPR] COG0477 Permeases of the major facilitator superfa... 671 0.0 CC0980 [GEPR] COG0477 Permeases of the major facilitator superfa... 668 0.0 mlr0338 [GEPR] COG0477 Permeases of the major facilitator superf... 658 0.0 SMc04407 [GEPR] COG0477 Permeases of the major facilitator super... 573 e-163 >RSc0547 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 567 Score = 766 bits (1977), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/549 (71%), Positives = 459/549 (83%), Gaps = 9/549 (1%) Query: 13 ITKEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIV 72 +T+EEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFF+G DP AFIFALLAFAAGF+V Sbjct: 20 MTREEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFSGLDPTAAFIFALLAFAAGFLV 79 Query: 73 RPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRILQG 132 RPFGALVFGRLGD++GRKYTFL+TILIMG STFIVG+LP+Y +IG AP+ILI+LR+LQG Sbjct: 80 RPFGALVFGRLGDMIGRKYTFLITILIMGTSTFIVGLLPSYTTIGAAAPVILIMLRLLQG 139 Query: 133 LALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTSVGEAAFADW 192 LALGGEYGGAATYVAEHAP GRRG++T+WIQTTAT+GLFLSL+VIL VR G A+F DW Sbjct: 140 LALGGEYGGAATYVAEHAPHGRRGNYTSWIQTTATLGLFLSLIVILVVRELTG-ASFEDW 198 Query: 193 GWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILAL 252 GWRIPFLVSI+LLA SV+IR+SM+ESPAF KMKAEGKTSKAPLTE+FGQW+NLK+VILAL Sbjct: 199 GWRIPFLVSIVLLATSVYIRLSMSESPAFQKMKAEGKTSKAPLTESFGQWRNLKIVILAL 258 Query: 253 VGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANLLIAAALLLATPFFLFFGSLSDKIGR 312 VGLTAGQAVVWYTGQFYALFFLTQ LKVD TAN+LIA AL + TPFF+FFGSLSD+IGR Sbjct: 259 VGLTAGQAVVWYTGQFYALFFLTQVLKVDAFTANVLIAVALAIGTPFFVFFGSLSDRIGR 318 Query: 313 KPIILGGCLIAAVTYFPIFNGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTK-K 371 K II+ GCL+A +TYFP+F LTH+ANPALE A Q + + + ADP C FQ +P + Sbjct: 319 KGIIMAGCLLAVLTYFPLFKALTHYANPALERAQQTAQITIKADPKECSFQGSPIAREVD 378 Query: 372 FTSSCDIVKAKLSAASVNYQNVAGAPGSVATVKIGERIITSYDATGLSKEE---AAAKDK 428 F SSCDI K L+ +S +Y++ G++A+V I R I S +A+ + + A +K K Sbjct: 379 FRSSCDIAKRTLAQSSASYESEDAPAGTIASVTIAGREIASLNASRTADGQNFDADSKKK 438 Query: 429 --ELSKALADDIKAAGYPAKADPEQINKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTR 486 + K+++D +KAA YP+KADP Q+N MVL++L ILVIYVTMVYGPIAA LVE+FPTR Sbjct: 439 ITDFKKSVSDALKAANYPSKADPAQMNTVMVLVILVILVIYVTMVYGPIAAMLVELFPTR 498 Query: 487 IRYTSMSMPYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIALITFVIGMLFVKET 546 IRYTSMS+PYHIGNGWFGGLLPT SFALVA G+IYYGLWYPI IA ITFVIG LFV+ET Sbjct: 499 IRYTSMSLPYHIGNGWFGGLLPTISFALVAQHGNIYYGLWYPIWIAAITFVIGALFVRET 558 Query: 547 VRNNI--HD 553 +I HD Sbjct: 559 KDVDIYRHD 567 >PA3709 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 539 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/538 (63%), Positives = 416/538 (77%), Gaps = 17/538 (3%) Query: 15 KEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIVRP 74 +EE+KVIFASSLGTVFEWYDF+LYG+LAA+I+KQFFAG + TAFIFAL+AFAAGF+VRP Sbjct: 18 QEERKVIFASSLGTVFEWYDFFLYGALAAVISKQFFAGVNDTTAFIFALMAFAAGFLVRP 77 Query: 75 FGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRILQGLA 134 FGALVFGRLGD++GRKYTFLVTIL+MG STF VG+LP Y SIG+ APIIL+ LR+LQGLA Sbjct: 78 FGALVFGRLGDMIGRKYTFLVTILLMGLSTFAVGLLPTYASIGVAAPIILVTLRMLQGLA 137 Query: 135 LGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTSVGEAAFADWGW 194 LGGEYGGAA YVAEHAP +RGS+T+WIQ+TAT+GL LSLLVIL R G+ F WGW Sbjct: 138 LGGEYGGAAIYVAEHAPANKRGSYTSWIQSTATLGLLLSLLVILACRQLTGDE-FETWGW 196 Query: 195 RIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVG 254 R+PFL+SI+LL IS WIR+SM ESPAFLKMKAEGK SKAPL E+F QW NLK+V+ AL Sbjct: 197 RLPFLLSIVLLGISTWIRLSMRESPAFLKMKAEGKVSKAPLRESFTQWGNLKVVLTALFS 256 Query: 255 LTAGQAVVWYTGQFYALFFLTQTLKVDGPTANLLIAAALLLATPFFLFFGSLSDKIGRKP 314 + AGQAV +YT QFY LFFLTQ LKVDG TAN L+ AL+L PFF+ G LSD+IGRKP Sbjct: 257 INAGQAVTFYTAQFYVLFFLTQVLKVDGGTANGLLIVALVLGAPFFIVAGWLSDRIGRKP 316 Query: 315 IILGGCLIAAVTYFPIFNGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTS 374 ++L G L+A + YFP+F GLTH+ANPA++ A ++SP+ V ADPA+C FQF+P G F S Sbjct: 317 VLLAGLLLATLFYFPLFKGLTHYANPAIDQASRQSPISVVADPATCTFQFDPVGKATFDS 376 Query: 375 SCDIVKAKLSAASVNYQNVAGAPGSVATVKIGERIITSYDATGLSKEEAAAKDKELSKAL 434 CD VK L A + Y VA GS V+IGE I +DA +A+ Sbjct: 377 PCDKVKTFLVKAGLPYSTVAAPAGSDVRVRIGETEIAGFDA----------------EAM 420 Query: 435 ADDIKAAGYPAKADPEQINKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSM 494 A +K AGYP +AD Q+NKPMV+ ++F LV+ T+ YGP+AA +VE+FPTRIRY+S+S+ Sbjct: 421 AAAVKTAGYPQQADGSQVNKPMVIAIIFALVLISTLCYGPLAALMVELFPTRIRYSSLSL 480 Query: 495 PYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIALITFVIGMLFVKETVRNNIH 552 PYHIGNGWFGG LPT SFALV + GDI+YGLWYP++I + V +LF++ET +IH Sbjct: 481 PYHIGNGWFGGFLPTVSFALVVYTGDIFYGLWYPVLITGGSLVCALLFLRETRHTDIH 538 >CC0980 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 567 Score = 668 bits (1723), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/538 (64%), Positives = 418/538 (77%) Query: 16 EEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIVRPF 75 + V+ ASSLGTVFEWYDFYLYGSLA II FF+G + T FI ALLAFAAGF +RP Sbjct: 30 RDTMVVGASSLGTVFEWYDFYLYGSLAPIITSHFFSGVNETTGFILALLAFAAGFAIRPL 89 Query: 76 GALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRILQGLAL 135 GAL+FGRLGDL GRK TFL+T+L+MG STF+VG+LP+Y IG+ API L+++R++QGLAL Sbjct: 90 GALIFGRLGDLWGRKNTFLITMLLMGVSTFVVGLLPSYAQIGVAAPIALVLMRLVQGLAL 149 Query: 136 GGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTSVGEAAFADWGWR 195 GGEYGGAATYVAEHAP G+RG +T+WIQTTAT+GLFLSL VIL R +GE AF WGWR Sbjct: 150 GGEYGGAATYVAEHAPPGKRGFYTSWIQTTATIGLFLSLAVILVARIQLGEEAFKAWGWR 209 Query: 196 IPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILALVGL 255 IPFLVS+LLL +S+WIR+ ++ESP F +M AEGK SK PLTEAFG W NLK+V+LALVGL Sbjct: 210 IPFLVSLLLLGVSLWIRLKLHESPTFERMIAEGKGSKKPLTEAFGNWPNLKIVLLALVGL 269 Query: 256 TAGQAVVWYTGQFYALFFLTQTLKVDGPTANLLIAAALLLATPFFLFFGSLSDKIGRKPI 315 T GQAVVWYTGQFYALFFL +TLK+DG AN L+A ALL+ TPFF+ G LSDKIGRKPI Sbjct: 270 TMGQAVVWYTGQFYALFFLEKTLKLDGALANTLVAVALLIGTPFFVICGWLSDKIGRKPI 329 Query: 316 ILGGCLIAAVTYFPIFNGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKFTSS 375 I+ GCL+AA+TYFPIF +T +ANPAL A +PV+VTAD A+C FQF+ G KF + Sbjct: 330 IILGCLLAALTYFPIFKAITTYANPALAKAEATAPVVVTADTATCAFQFDLIGKAKFNTP 389 Query: 376 CDIVKAKLSAASVNYQNVAGAPGSVATVKIGERIITSYDATGLSKEEAAAKDKELSKALA 435 CD+ KA L+ A V+Y A G+ VK+G+ + D+ G + + A K L Sbjct: 390 CDVAKAYLAKAGVSYSVQAAPAGTPTAVKVGDVTLEGLDSKGATGQAFADARKAWEADLG 449 Query: 436 DDIKAAGYPAKADPEQINKPMVLLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMP 495 +KAAGYPAKAD +NKP V+ LL +LVIYVTMVYGPIAA LVE+FPTRIRYT+MS+P Sbjct: 450 AQLKAAGYPAKADAALVNKPAVIGLLALLVIYVTMVYGPIAAMLVELFPTRIRYTAMSLP 509 Query: 496 YHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIVIALITFVIGMLFVKETVRNNIHD 553 YHIGNGWFGG LPTT+FA+VA GDIY GLWYP++IA IT V+G LF+K+T N + D Sbjct: 510 YHIGNGWFGGFLPTTAFAIVAATGDIYSGLWYPVIIAAITAVVGGLFLKDTRHNRLED 567 >mlr0338 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 629 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/622 (56%), Positives = 433/622 (69%), Gaps = 73/622 (11%) Query: 4 ASVNTTTRGITKEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPN-TAFIFA 62 ++ T+RG+T+EEKKVIFASSLGTVFEWYDFYLYGSLAA I FF+ T P T IFA Sbjct: 5 STAGRTSRGMTREEKKVIFASSLGTVFEWYDFYLYGSLAAFIGSTFFSPTIPEATRNIFA 64 Query: 63 LLAFAAGFIVRPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPI 122 LLAFAAGF+VRPFGALVFGR+GDLVGRKYTFLVT+ IMG STF+VG+LP Y ++GI AP+ Sbjct: 65 LLAFAAGFLVRPFGALVFGRIGDLVGRKYTFLVTMTIMGLSTFLVGLLPGYATLGIAAPV 124 Query: 123 ILIILRILQGLALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRT 182 ILI LR+LQGLALGGEYGGAATYVAEHAP+ RRG +T+WIQTTAT+GLFLSL+VIL V+ Sbjct: 125 ILIALRMLQGLALGGEYGGAATYVAEHAPDDRRGFYTSWIQTTATLGLFLSLIVILIVQG 184 Query: 183 SVGEAAFADWGWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQW 242 S+ + +A WGWRIPF+VS +LLA+S+WIR+S++ESP F KMK EGK SKAPL+EAFGQW Sbjct: 185 SLSKETYAAWGWRIPFIVSFVLLAVSIWIRLSLSESPTFQKMKDEGKGSKAPLSEAFGQW 244 Query: 243 KNLKLVILALVGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANLLIAAALLLATPFFLF 302 KN K+ +LAL+GLTAGQAVVWY GQFYALFFL LKVD + N++IA AL L + FF+ Sbjct: 245 KNAKIALLALLGLTAGQAVVWYNGQFYALFFLQNVLKVDAQSVNIMIAIALALGSIFFVV 304 Query: 303 FGSLSDKIGRKPIILGGCLIAAVTYFPIFNGLTHFANPALEAALQKSPVIVTADPASCQF 362 FG LSDKIGRKPII+ G +A V FP+F LT ANPAL A Q + VTA P C+F Sbjct: 305 FGWLSDKIGRKPIIMAGLALAIVCTFPLFKALTWAANPALATAQQNTRATVTAAPGDCKF 364 Query: 363 QFNPTGTKKFTSSCDIVKAKLSAASVNYQNV----AGAPGSV------------------ 400 QFNP GT KFT+SCDI + L+ SV + V AG P +V Sbjct: 365 QFNPVGTAKFTTSCDIATSFLTKNSVPFDVVSTAAAGTPATVKIGNETVASYDAVAAGDQ 424 Query: 401 -------------------------ATVKIGERIITSY---------DATGLSKEEAAA- 425 A +K+ ++ + ++ DA + E A Sbjct: 425 AKAKDAAFVKAVNMSLKDGGYPLKRAAIKVADQKLDAFIAANPELKLDAATIRGGEKATV 484 Query: 426 -KDKELSKALADDIKAAGYPAK--------------ADPEQINKPMVLLLLFILVIYVTM 470 ++ + L +AAG P ADP +N PM + +LFILV++VTM Sbjct: 485 PTEQAVKDKLVTSEEAAGAPEVTVYNIPGGGAFAMFADPAAVNWPMTIGILFILVLFVTM 544 Query: 471 VYGPIAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSFALVAFKGDIYYGLWYPIV 530 VYGPIAA LVEMFPTRIRYT MS+PYHIGNGWFGGLLP T FAL A++GDIY+GLWYP+V Sbjct: 545 VYGPIAAILVEMFPTRIRYTGMSLPYHIGNGWFGGLLPATVFALSAYRGDIYFGLWYPVV 604 Query: 531 IALITFVIGMLFVKETVRNNIH 552 IA +T +IGM+FVK+T+ ++ Sbjct: 605 IAAMTLIIGMIFVKDTLGTDLR 626 >SMc04407 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 629 Score = 573 bits (1478), Expect = e-163, Method: Compositional matrix adjust. Identities = 299/433 (69%), Positives = 340/433 (78%), Gaps = 2/433 (0%) Query: 13 ITKEEKKVIFASSLGTVFEWYDFYLYGSLAAIIAKQFFAGTDPNTAFIFALLAFAAGFIV 72 +T EEKKVIFASSLGTVFEWYDFYLYGSLA I FF+ T IFALLAFAAGF+V Sbjct: 15 MTGEEKKVIFASSLGTVFEWYDFYLYGSLAVYIGATFFSQYPETTRNIFALLAFAAGFLV 74 Query: 73 RPFGALVFGRLGDLVGRKYTFLVTILIMGASTFIVGVLPNYNSIGITAPIILIILRILQG 132 RPFGALVFGRLGDLVGRKYTFLVTILIMG STF+VGVLP SIGI APIILI LR+LQG Sbjct: 75 RPFGALVFGRLGDLVGRKYTFLVTILIMGVSTFLVGVLPGAASIGIAAPIILIALRLLQG 134 Query: 133 LALGGEYGGAATYVAEHAPEGRRGSFTAWIQTTATMGLFLSLLVILGVRTSVGEAAFADW 192 LALGGEYGGAATYVAEHAP GRRG FT+WIQTTAT+GLFLSL+VIL V+ +G+ AFA+W Sbjct: 135 LALGGEYGGAATYVAEHAPHGRRGYFTSWIQTTATLGLFLSLVVILLVQYMLGKEAFAEW 194 Query: 193 GWRIPFLVSILLLAISVWIRMSMNESPAFLKMKAEGKTSKAPLTEAFGQWKNLKLVILAL 252 GWRIPFL+S +LL +SVWIR+ MNESPAF KMK EGK SKAPLTEAFGQW+N K+ +LAL Sbjct: 195 GWRIPFLLSFVLLGVSVWIRLKMNESPAFKKMKEEGKGSKAPLTEAFGQWRNAKIAVLAL 254 Query: 253 VGLTAGQAVVWYTGQFYALFFLTQTLKVDGPTANLLIAAALLLATPFFLFFGSLSDKIGR 312 G GQAVVWY+GQFYALFFL LKVDG +ANL++AA+LLL T FF+FFG LSDKIGR Sbjct: 255 FGAVVGQAVVWYSGQFYALFFLQSILKVDGQSANLMVAASLLLGTGFFVFFGWLSDKIGR 314 Query: 313 KPIILGGCLIAAVTYFPIFNGLTHFANPALEAALQKSPVIVTADPASCQFQFNPTGTKKF 372 KPII+ G L+A +TYFP+F LT NPAL A Q VTA P C+FQFNPTGT KF Sbjct: 315 KPIIMAGLLLAMLTYFPLFKALTWAGNPALAEAQQSVRATVTAAPGDCKFQFNPTGTAKF 374 Query: 373 TSSCDIVKAKLSAASVNYQNV-AGAPGSVATVKIGERIITSYDATGLSKEEAAAKDKELS 431 T+SCDI A L+ SV Y V A G+ ATVKIGE ITSYDA + + A A++ Sbjct: 375 TTSCDIATAFLTKNSVPYDVVTTAAAGTPATVKIGETTITSYDAIA-AGDRAKAEEAAFG 433 Query: 432 KALADDIKAAGYP 444 K + ++A+GYP Sbjct: 434 KQINMALQASGYP 446 Score = 169 bits (428), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 86/155 (55%), Positives = 108/155 (69%), Gaps = 5/155 (3%) Query: 401 ATVKIGERIITSYD---ATGLSKEEAAAKDKELSKALADDIKAAGYPAKADPEQINKPMV 457 A V+ GE+ + D A L +E E+ A+ + K + ADP ++N ++ Sbjct: 474 AAVRAGEKTMVPADKLVADKLLTQEEVGSATEM--AVYNIDKGGAFTMVADPARVNWTVI 531 Query: 458 LLLLFILVIYVTMVYGPIAACLVEMFPTRIRYTSMSMPYHIGNGWFGGLLPTTSFALVAF 517 + +L +LVIYVTMVYGPIAA LVE+FPTRIRYT MS+PYHIGNGWFGGLLP T+FA+ A Sbjct: 532 IAVLTVLVIYVTMVYGPIAALLVELFPTRIRYTGMSLPYHIGNGWFGGLLPATAFAMSAA 591 Query: 518 KGDIYYGLWYPIVIALITFVIGMLFVKETVRNNIH 552 KGDIYYGLWYPIV A IT VIG+LF+ ET +IH Sbjct: 592 KGDIYYGLWYPIVFAGITLVIGLLFLPETKDRDIH 626