BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2058.p (489 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1429_3 [F] COG0516 IMP dehydrogenase/GMP reductase Rso Ralsto... 478 e-134 NMA1372_3 [F] COG0516 IMP dehydrogenase/GMP reductase NmA Neisse... 405 e-112 NMB1201_3 [F] COG0516 IMP dehydrogenase/GMP reductase Nme Neisse... 404 e-112 YPO2871_3 [F] COG0516 IMP dehydrogenase/GMP reductase Ype Yersin... 396 e-110 Cj1058c_3 [F] COG0516 IMP dehydrogenase/GMP reductase Cje Campyl... 371 e-102 >RSc1429_3 [F] COG0516 IMP dehydrogenase/GMP reductase Rso Ralstonia solanacearum Length = 290 Score = 478 bits (1231), Expect = e-134, Method: Compositional matrix adjust. Identities = 232/289 (80%), Positives = 261/289 (90%), Gaps = 3/289 (1%) Query: 201 DIEKSTEHPFACKDVHGKLRVGAAVGVGPDNDERIELLVAAGVDVIVVDTAHGHSAGVLN 260 DI+K+TEHP A KD G LRVGAAVGVGPDND R++LLV AGVDVIVVDTAHGHS GVL+ Sbjct: 1 DIQKATEHPLASKDERGSLRVGAAVGVGPDNDLRVDLLVKAGVDVIVVDTAHGHSQGVLS 60 Query: 261 RVKWVKTKYPHVEVIGGNIATAAAAKALVEHGADAVKVGIGPGSICTTRIVAGVGVPQIS 320 RV+W+K KYP V+VIGGNIATA AAKALV+HGAD VKVGIGPGSICTTRIVAGVGVPQIS Sbjct: 61 RVRWIKDKYPQVQVIGGNIATAEAAKALVDHGADGVKVGIGPGSICTTRIVAGVGVPQIS 120 Query: 321 AIANVAEALKGTGVPVIADGGIRFSGDVAKALAAGASAVMMGSMFAGTEEAPGEVILYQG 380 A++NVAEALK TGVP++ADGG+R+SGD+AKALAAGA VMMG MFAGTEEAPGEV LYQG Sbjct: 121 AVSNVAEALKNTGVPLVADGGVRYSGDIAKALAAGAHTVMMGGMFAGTEEAPGEVFLYQG 180 Query: 381 RSYKSYRGMGSLGAMADGSADRYFQDGDNTA--DKFVPEGIEGRVAYKGSVVAILYQLVG 438 RSYKSYRGMGS+GAM DG+ADRYFQ+ DNTA DK VPEGIEGRV YKGSV+ I++QL G Sbjct: 181 RSYKSYRGMGSVGAMKDGAADRYFQE-DNTANVDKLVPEGIEGRVPYKGSVLPIVHQLTG 239 Query: 439 GVRSSMGYCGCASIDDFRERAEFVEITAAGMRESHVHDVQITKEAPNYR 487 G+RSSMGYCGCASI ++ E+++FV+ITAAGMRESHVHDVQITKEAPNY Sbjct: 240 GIRSSMGYCGCASIAEWHEKSQFVQITAAGMRESHVHDVQITKEAPNYH 288 >NMA1372_3 [F] COG0516 IMP dehydrogenase/GMP reductase NmA Neisseria meningitidis Z2491 Length = 246 Score = 405 bits (1041), Expect = e-112, Method: Compositional matrix adjust. Identities = 196/245 (80%), Positives = 220/245 (89%) Query: 243 VDVIVVDTAHGHSAGVLNRVKWVKTKYPHVEVIGGNIATAAAAKALVEHGADAVKVGIGP 302 VDVIVVDTAHGHS GV++RV+WVK YPH++VIGGNIATA AA LV GADAVKVGIGP Sbjct: 1 VDVIVVDTAHGHSQGVIDRVRWVKETYPHIQVIGGNIATAKAALDLVAAGADAVKVGIGP 60 Query: 303 GSICTTRIVAGVGVPQISAIANVAEALKGTGVPVIADGGIRFSGDVAKALAAGASAVMMG 362 GSICTTRIVAGVGVPQ++AI NVAEALKGTGVP+IADGGIRFSGD+AKALAAGA +VM+G Sbjct: 61 GSICTTRIVAGVGVPQLTAIHNVAEALKGTGVPLIADGGIRFSGDIAKALAAGAYSVMLG 120 Query: 363 SMFAGTEEAPGEVILYQGRSYKSYRGMGSLGAMADGSADRYFQDGDNTADKFVPEGIEGR 422 MFAGTEEAPGE+ LYQGRSYKSYRGMGSLGAM+ GSADRYFQD ++ADK+VPEGIEGR Sbjct: 121 GMFAGTEEAPGEIELYQGRSYKSYRGMGSLGAMSQGSADRYFQDKTDSADKYVPEGIEGR 180 Query: 423 VAYKGSVVAILYQLVGGVRSSMGYCGCASIDDFRERAEFVEITAAGMRESHVHDVQITKE 482 V YKG +V I++QL GG+RSSMGY GCA+I + E+AEFVEIT+AGM ESHVHDVQITKE Sbjct: 181 VPYKGPIVNIIHQLTGGLRSSMGYLGCANIAEMHEKAEFVEITSAGMSESHVHDVQITKE 240 Query: 483 APNYR 487 APNY Sbjct: 241 APNYH 245 >NMB1201_3 [F] COG0516 IMP dehydrogenase/GMP reductase Nme Neisseria meningitidis MC58 Length = 246 Score = 404 bits (1038), Expect = e-112, Method: Compositional matrix adjust. Identities = 195/245 (79%), Positives = 219/245 (89%) Query: 243 VDVIVVDTAHGHSAGVLNRVKWVKTKYPHVEVIGGNIATAAAAKALVEHGADAVKVGIGP 302 VDVIVVDTAHGHS GV++RV+WVK YPH++VIGGNIATA AA LV GADAVKVGIGP Sbjct: 1 VDVIVVDTAHGHSQGVIDRVRWVKETYPHIQVIGGNIATAKAALDLVAAGADAVKVGIGP 60 Query: 303 GSICTTRIVAGVGVPQISAIANVAEALKGTGVPVIADGGIRFSGDVAKALAAGASAVMMG 362 GSICTTRIVAGVGVPQ++AI NVAEALKGTGVP+IADGGIRFSGD+AKALAAGA +VM+G Sbjct: 61 GSICTTRIVAGVGVPQLTAIHNVAEALKGTGVPLIADGGIRFSGDIAKALAAGAYSVMLG 120 Query: 363 SMFAGTEEAPGEVILYQGRSYKSYRGMGSLGAMADGSADRYFQDGDNTADKFVPEGIEGR 422 MFAGTEEAPGE+ LYQGRSYKSYRGMGSLGAM+ GSADRYFQD ++ DK+VPEGIEGR Sbjct: 121 GMFAGTEEAPGEIELYQGRSYKSYRGMGSLGAMSQGSADRYFQDKTDSTDKYVPEGIEGR 180 Query: 423 VAYKGSVVAILYQLVGGVRSSMGYCGCASIDDFRERAEFVEITAAGMRESHVHDVQITKE 482 V YKG +V I++QL GG+RSSMGY GCA+I + E+AEFVEIT+AGM ESHVHDVQITKE Sbjct: 181 VPYKGPIVNIIHQLTGGLRSSMGYLGCANIAEMHEKAEFVEITSAGMSESHVHDVQITKE 240 Query: 483 APNYR 487 APNY Sbjct: 241 APNYH 245 >YPO2871_3 [F] COG0516 IMP dehydrogenase/GMP reductase Ype Yersinia pestis Length = 281 Score = 396 bits (1018), Expect = e-110, Method: Compositional matrix adjust. Identities = 195/279 (69%), Positives = 238/279 (85%), Gaps = 1/279 (0%) Query: 209 PFACKDVHGKLRVGAAVGVGPDNDERIELLVAAGVDVIVVDTAHGHSAGVLNRVKWVKTK 268 P ACKD HG+LRVGAAVG G N+ERI+ LVAAGVDV+++D++HGHS GVL R++ + K Sbjct: 2 PNACKDEHGRLRVGAAVGAGAGNEERIDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAK 61 Query: 269 YPHVEVIGGNIATAAAAKALVEHGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAEA 328 YP+++++GGN+AT A AKAL + G AVKVGIGPGSICTTRIV GVGVPQI+AIA+ EA Sbjct: 62 YPNLQIVGGNVATGAGAKALADAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAVEA 121 Query: 329 LKGTGVPVIADGGIRFSGDVAKALAAGASAVMMGSMFAGTEEAPGEVILYQGRSYKSYRG 388 L+GTG+PVIADGGIRFSGD+AKA+AAGAS VM+GSM AGTEE+PGE+ LYQGRS+KSYRG Sbjct: 122 LEGTGIPVIADGGIRFSGDIAKAIAAGASCVMVGSMLAGTEESPGEIELYQGRSFKSYRG 181 Query: 389 MGSLGAMADGSADRYFQDGDNTADKFVPEGIEGRVAYKGSVVAILYQLVGGVRSSMGYCG 448 MGSLGAM+ GS+DRYFQ DN ADK VPEGIEGRVAYKG + I++Q +GG+RS MG G Sbjct: 182 MGSLGAMSKGSSDRYFQT-DNAADKLVPEGIEGRVAYKGLLKEIVHQQMGGLRSCMGLTG 240 Query: 449 CASIDDFRERAEFVEITAAGMRESHVHDVQITKEAPNYR 487 C +I++ R +AEFV I+ AG++ESHVHDV ITKE+PNYR Sbjct: 241 CGTINELRTKAEFVRISGAGIQESHVHDVTITKESPNYR 279 >Cj1058c_3 [F] COG0516 IMP dehydrogenase/GMP reductase Cje Campylobacter jejuni Length = 285 Score = 371 bits (953), Expect = e-102, Method: Compositional matrix adjust. Identities = 191/284 (67%), Positives = 232/284 (81%), Gaps = 3/284 (1%) Query: 204 KSTEHPFACKDVHGKLRVGAAVGVGPDNDERIELLVAAGVDVIVVDTAHGHSAGVLNRVK 263 K E+P A KD G+LRVGAA+GVG +R++ LV AGVDV+V+D+AHGHS G+++ VK Sbjct: 1 KRKEYPDANKDNFGRLRVGAAIGVG--QMDRVDALVEAGVDVVVLDSAHGHSKGIIDTVK 58 Query: 264 WVKTKYPHVEVIGGNIATAAAAKALVEHGADAVKVGIGPGSICTTRIVAGVGVPQISAIA 323 +K KYP++++I GNIATAAAAKAL E G DAVKVGIGPGSICTTRIV+GVGVPQISAI Sbjct: 59 AIKAKYPNLDLIAGNIATAAAAKALCEAGVDAVKVGIGPGSICTTRIVSGVGVPQISAID 118 Query: 324 NVAEALKGTGVPVIADGGIRFSGDVAKALAAGASAVMMGSMFAGTEEAPGEVILYQGRSY 383 E GVPVIADGGI++SGD+AKALA GAS+VM+GS+ AGT+E+PGE+ YQGR Y Sbjct: 119 ECVEEANKFGVPVIADGGIKYSGDIAKALAVGASSVMIGSLLAGTDESPGELFTYQGRQY 178 Query: 384 KSYRGMGSLGAMADGSADRYFQDGDNTADKFVPEGIEGRVAYKGSVVAILYQLVGGVRSS 443 KSYRGMGSLGAM GS+DRYFQ G DK VPEGIEGRV Y GS+ ++++QL+GG+RSS Sbjct: 179 KSYRGMGSLGAMQKGSSDRYFQQG-TAQDKLVPEGIEGRVPYVGSIRSVVHQLLGGLRSS 237 Query: 444 MGYCGCASIDDFRERAEFVEITAAGMRESHVHDVQITKEAPNYR 487 MGY G I+DF++RAEFVEIT AG++ESHVHDV IT EAPNY+ Sbjct: 238 MGYVGAKDIEDFQKRAEFVEITTAGLKESHVHDVTITHEAPNYK 281