BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.2043.p (391 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1417 [M] COG0763 Lipid A disaccharide synthetase Rso Ralstoni... 356 6e-98 PA3643 [M] COG0763 Lipid A disaccharide synthetase Pae Pseudomon... 305 9e-83 NMB0199 [M] COG0763 Lipid A disaccharide synthetase Nme Neisseri... 304 2e-82 NMA0069 [M] COG0763 Lipid A disaccharide synthetase NmA Neisseri... 303 4e-82 PM1997 [M] COG0763 Lipid A disaccharide synthetase Pmu Pasteurel... 285 1e-76 >RSc1417 [M] COG0763 Lipid A disaccharide synthetase Rso Ralstonia solanacearum Length = 390 Score = 356 bits (913), Expect = 6e-98, Method: Compositional matrix adjust. Identities = 195/380 (51%), Positives = 247/380 (65%), Gaps = 7/380 (1%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLP-EVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFE 71 I + AGE+SGDLL S LL G+ RLP +V GIGG M QGF S WPM KL+V G E Sbjct: 12 IGMAAGEASGDLLASLLLKGLHARLPRDVAYEGIGGARMAEQGFASHWPMHKLSVNGYVE 71 Query: 72 VIPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWA 131 V+ + REI I+ L+ LLAD P F+GVD P FN +E +++AG+P +HF+ P IWA Sbjct: 72 VLGQLREILAIRRELKQNLLADPPMAFIGVDAPDFNFNVEIAMRRAGVPVVHFVSPSIWA 131 Query: 132 WRGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTPGARQRLGL 191 WR RIK I RAV H+L +FPFE IY +AG+P TYVGHPLA+ IPL+PD GAR RLGL Sbjct: 132 WRAGRIKTIARAVDHILCLFPFEPEIYARAGIPATYVGHPLADEIPLEPDVEGARSRLGL 191 Query: 192 TGPGRVVAILPGSRMSELKQNGEGFLAAARLLQQRDGQLQFVTPMAGERQMAFFEEQIRQ 251 +VVA+LPGSR SE+K G AA +Q + L FV P A A E+I Sbjct: 192 PLGRKVVAVLPGSRNSEVKLLGPTLFAAMARMQAVEPDLAFVLPAAN----AMLRERIDA 247 Query: 252 GGYEDLGIS--VIRGQSHSAMEASDAVLVASGTASLEVALYKKPMVISYKVNWASYQIMR 309 E G+ V+ GQSH+AMEA+D +L+ASGTA+LE ALYKKPMVI+YKV W + QIM+ Sbjct: 248 MRAEHPGLHLWVVDGQSHAAMEAADVILLASGTATLEAALYKKPMVITYKVPWLTAQIMK 307 Query: 310 HMAYQPWVGLPNILAREFLVPELLQHQATPQALADAMWFQLEDHAHQQRLARRFADLHQS 369 Y P+VGLPNIL+ F+VPELLQ ATP+ALA QL DHA+ L F +H + Sbjct: 308 RKGYLPYVGLPNILSGRFVVPELLQDDATPEALARETLLQLSDHANAAFLREHFTQMHLT 367 Query: 370 LLRDTSRESANAVCEVMGAR 389 L ++ + A V +++ R Sbjct: 368 LKQNMADIGAQVVVDLLRGR 387 >PA3643 [M] COG0763 Lipid A disaccharide synthetase Pae Pseudomonas aeruginosa Length = 378 Score = 305 bits (782), Expect = 9e-83, Method: Compositional matrix adjust. Identities = 175/380 (46%), Positives = 249/380 (65%), Gaps = 11/380 (2%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFEV 72 +ALVAGE+SGD+LGS L+ +R R P++ G+GG M A+G +S +PM++L+V GL EV Sbjct: 7 VALVAGEASGDILGSGLMQALRARHPDIEFIGVGGPRMEAEGLSSYFPMERLSVMGLVEV 66 Query: 73 IPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWAW 132 + R E+ + L L+ RPDV +G+D P F LG+E +L++AG+ T+H++ P +WAW Sbjct: 67 LGRLPELLRRRKRLIRTLIEARPDVMIGIDAPDFTLGVEHKLRQAGLRTVHYVSPSVWAW 126 Query: 133 RGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTPGARQRLGLT 192 R R+ KI+ A ML +FPFE Y + GVPV +VGHPLA IPLQ D AR RLGL Sbjct: 127 RQKRVLKIREACDLMLALFPFEARFYEEHGVPVRFVGHPLANTIPLQADRAAARARLGLP 186 Query: 193 GPGRVVAILPGSRMSELKQNGEGFL-AAARLLQQRDGQLQFVTPMAGERQMAFFEEQIRQ 251 G+V+A++PGSR E+ + G FL A RLL +R G L+FV P A A EQI Q Sbjct: 187 ADGQVLALMPGSRGGEVGKLGALFLDTAQRLLVERPG-LRFVLPCAS----AARREQIEQ 241 Query: 252 --GGYEDLGISVIRGQSHSAMEASDAVLVASGTASLEVALYKKPMVISYKVNWASYQIMR 309 G E L ++++ G SH A+ A DAVL+ASGTA+LE LYK+PMV++Y+V +Y+I++ Sbjct: 242 MLQGREPLPLTLLDGASHEALAACDAVLIASGTATLEALLYKRPMVVAYRVAGLTYRILK 301 Query: 310 HMAYQPWVGLPNILAREFLVPELLQHQATPQALADAMWFQLEDHAHQQRLARRFADLHQS 369 + P++ LPN+LA LVPEL+Q ATPQALA + L+D + Q F +H++ Sbjct: 302 RLVKSPYISLPNLLAGRLLVPELIQDAATPQALAATLSPLLDDGSQQVEF---FDAIHRA 358 Query: 370 LLRDTSRESANAVCEVMGAR 389 L +D S ++A AV +++ R Sbjct: 359 LRQDASAQAAEAVLQLVERR 378 >NMB0199 [M] COG0763 Lipid A disaccharide synthetase Nme Neisseria meningitidis MC58 Length = 390 Score = 304 bits (779), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 168/378 (44%), Positives = 235/378 (62%), Gaps = 4/378 (1%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFEV 72 IA+ GE+SGDLLG+ L+ +R+R P+ R GIGGE M A+GF S + ++L VRG EV Sbjct: 15 IAVSVGEASGDLLGAHLIRAIRKRCPQARFTGIGGELMKAEGFESLYDQERLAVRGFVEV 74 Query: 73 IPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWAW 132 + R EI I+ L LL+ +PDVFVG+D P FNLG+ E+LK++GIPT+H++ P +WAW Sbjct: 75 VRRLPEILRIRRGLVRDLLSLKPDVFVGIDAPDFNLGVAEKLKRSGIPTVHYVSPSVWAW 134 Query: 133 RGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTPGARQRLGLT 192 R R+ KI V+ +L +FP E +Y AG +VGHP+A+++PL+ D ARQ LG+ Sbjct: 135 RRERVGKIVHQVNRVLCLFPMEPQLYLDAGGRAEFVGHPMAQLMPLEDDRETARQTLGVD 194 Query: 193 GPGRVVAILPGSRMSELKQNGEGFLAAARLLQQRDGQLQFVTPMAGERQMAFFEEQIRQG 252 V A+LPGSR+SE+ F A LL +R +F+ P A E E +++ Sbjct: 195 AGIPVFALLPGSRVSEIDYMAPVFFQTALLLLERYPAARFLLPAATEATKRRLAEVLQRP 254 Query: 253 GYEDLGISVIRGQSHSAMEASDAVLVASGTASLEVALYKKPMVISYKVNWASYQIMRHMA 312 + L ++VI QS + A+DAVLV SGTA+LEVAL K+PMVISYK++ +Y ++ Sbjct: 255 EFAGLPLTVIDRQSETVCRAADAVLVTSGTATLEVALCKRPMVISYKISPLTYAYVKRKI 314 Query: 313 YQPWVGLPNILAREFLVPELLQHQATPQALADAM--WFQLEDHAHQQRLARRFADLHQSL 370 P VGLPNIL + VPELLQ +A P+ LA A+ W++ D L + F LH L Sbjct: 315 KVPHVGLPNILLGKEAVPELLQSEAKPEKLAAALADWYEHPDKVAA--LQQDFRALHLLL 372 Query: 371 LRDTSRESANAVCEVMGA 388 +DT+ +A AV E G Sbjct: 373 KKDTADLAARAVLEEAGC 390 >NMA0069 [M] COG0763 Lipid A disaccharide synthetase NmA Neisseria meningitidis Z2491 Length = 384 Score = 303 bits (777), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 167/378 (44%), Positives = 234/378 (61%), Gaps = 4/378 (1%) Query: 13 IALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFEV 72 IA+ GE+SGDLLG+ L+ +R+R P+ R GIGGE M A+GF S + ++L VRG EV Sbjct: 9 IAVSVGEASGDLLGAHLIRAIRKRCPQARFVGIGGELMKAEGFESLYDQERLAVRGFVEV 68 Query: 73 IPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWAW 132 + R EI I+ L LL+ +PDVFVG+D P FNLG+ E+LK++GIPT+H++ P +WAW Sbjct: 69 VRRLPEILRIRRGLVRDLLSLKPDVFVGIDAPDFNLGVAERLKRSGIPTVHYVSPSVWAW 128 Query: 133 RGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTPGARQRLGLT 192 R R+ KI V+ +L +FP E +Y AG +VGHP+A+++PL+ D AR+ LG+ Sbjct: 129 RRERVGKIVHQVNRVLCLFPMEPQLYLDAGGRAEFVGHPMAQLMPLEDDRETARKTLGVD 188 Query: 193 GPGRVVAILPGSRMSELKQNGEGFLAAARLLQQRDGQLQFVTPMAGERQMAFFEEQIRQG 252 V A+LPGSR+SE+ F A LL +R +F+ P A E E +++ Sbjct: 189 AGIPVFALLPGSRVSEIDYMAPVFFQTALLLLKRYPAARFLLPAATEATKRRLAEILQRS 248 Query: 253 GYEDLGISVIRGQSHSAMEASDAVLVASGTASLEVALYKKPMVISYKVNWASYQIMRHMA 312 + L ++V QS + A+DAVLV SGTA+LEVAL K+PMVISYK++ +Y ++ Sbjct: 249 EFAGLPLTVTDRQSETVCRAADAVLVTSGTATLEVALCKRPMVISYKISPLTYAYVKRKI 308 Query: 313 YQPWVGLPNILAREFLVPELLQHQATPQALADAM--WFQLEDHAHQQRLARRFADLHQSL 370 P VGLPNIL + VPELLQH A P+ LA A+ W++ D L + F LH L Sbjct: 309 KVPHVGLPNILLGKEAVPELLQHDAVPEKLAAALADWYEHPDKVAA--LQQDFRVLHLLL 366 Query: 371 LRDTSRESANAVCEVMGA 388 +DT+ +A AV E G Sbjct: 367 KKDTADLAARAVLEEAGC 384 >PM1997 [M] COG0763 Lipid A disaccharide synthetase Pmu Pasteurella multocida Length = 392 Score = 285 bits (730), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 151/379 (39%), Positives = 236/379 (62%), Gaps = 5/379 (1%) Query: 12 SIALVAGESSGDLLGSRLLAGVRERLPEVRLHGIGGEHMMAQGFTSDWPMDKLTVRGLFE 71 +IA+VAGE SGD+LG+ L+ ++ + P R GI G M+A+G + M++L+V GL E Sbjct: 10 TIAIVAGEVSGDILGAGLIRSLKVQYPHARFIGIAGPRMLAEGAETLVDMEELSVMGLAE 69 Query: 72 VIPRYREIKGIQDALRDKLLADRPDVFVGVDYPGFNLGLEEQLKKAGIPTIHFIGPQIWA 131 V+ + I+ L +L ++PD+F+G+D P FN+ +E +LK+ GI TIH++ P +WA Sbjct: 70 VVKHLPRLLKIRRQLIHTMLQEKPDIFIGIDAPDFNIDVELKLKENGIKTIHYVSPSVWA 129 Query: 132 WRGWRIKKIQRAVSHMLVIFPFEESIYRQAGVPVTYVGHPLAEVIPLQPDTPGARQRLGL 191 WR RI KI +A +L PFE++ Y + VP ++GH +A+ I L+P+ A + L L Sbjct: 130 WRQNRIHKIAKATHLVLAFLPFEKAFYDRFEVPCRFIGHTMADAIALKPNRQEACEYLNL 189 Query: 192 TGPGRVVAILPGSRMSELKQNGEGFLAAARLLQQRDGQLQFVTPMAGERQMAFFEEQIRQ 251 R VAIL GSR SE+ E FL AA+LL+Q+ +QF+ P+ ++ F EQI+ Sbjct: 190 DASQRYVAILVGSRGSEVTFLAEPFLQAAKLLKQQYPDIQFLVPLINAKRREQF-EQIKA 248 Query: 252 GGYEDLGISVIRGQSHSAMEASDAVLVASGTASLEVALYKKPMVISYKVNWASYQIMRHM 311 +L + ++ G++ AM A++A L+ASGTA+LE L K PMV+ Y++ +Y + + + Sbjct: 249 QVAPELELILLDGKARQAMIAAEATLLASGTAALEAMLCKSPMVVGYRMKATTYFLAKRL 308 Query: 312 AYQPWVGLPNILAREFLVPELLQHQATPQALAD--AMWFQLEDHAHQQR--LARRFADLH 367 +V LPN+LA E LVPEL+Q Q T + LA+ A++ E+ A QQR L +RF DLH Sbjct: 309 VKTEYVSLPNLLANEMLVPELIQEQCTAENLAEKLALYLSQEESALQQRHTLIQRFTDLH 368 Query: 368 QSLLRDTSRESANAVCEVM 386 + + D +++A AV ++ Sbjct: 369 KLIQCDADKQAAQAVIALL 387