BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1984.p (212 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2155 [F] COG0194 Guanylate kinase Rso Ralstonia solanacearum 303 2e-82 XF1503 [F] COG0194 Guanylate kinase Xfa Xylella fastidiosa 9a5c 211 1e-54 VC2708 [F] COG0194 Guanylate kinase Vch Vibrio cholerae 208 7e-54 STM3740 [F] COG0194 Guanylate kinase Sty Salmonella typhimurium LT2 207 2e-53 gmk [F] COG0194 Guanylate kinase Eco Escherichia coli K12 206 4e-53 >RSc2155 [F] COG0194 Guanylate kinase Rso Ralstonia solanacearum Length = 221 Score = 303 bits (776), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 144/209 (68%), Positives = 171/209 (81%) Query: 2 PVQKPTSGSLFMVVAPSGAGKSTLVNALLKQEPSIKLSISYTTRAPRPGEEHGREYYFTD 61 P++ GSLFMVVAPSGAGKSTLVNALL Q+PSI+LS+S TTR PRPGE+HGREY F Sbjct: 13 PIENHFPGSLFMVVAPSGAGKSTLVNALLAQDPSIRLSVSATTRKPRPGEQHGREYNFMT 72 Query: 62 VDDFLKRQAEGEFLEWAEVHGNYYGTSRLMIADQIANGTDVLLEIDWQGAQQVKKQFTNA 121 VD+F + GEFLEWAEVHGNYY TSR+ I +Q+ GTDVLLEIDWQGAQQV ++F NA Sbjct: 73 VDEFKACRDRGEFLEWAEVHGNYYATSRVWIEEQMRAGTDVLLEIDWQGAQQVHRRFANA 132 Query: 122 IGIFILPPSIAALEERLKKRGQDEPHVITRRILAAGGEIAHSPEFEYVIINQEFAVALSE 181 + IFILPPS+ ALE+RLKKRGQDEP+VI RR+LAAG E+AH+PE +YVIIN+ F AL+E Sbjct: 133 VEIFILPPSLTALEDRLKKRGQDEPNVIVRRLLAAGSEMAHAPEADYVIINEVFEAALAE 192 Query: 182 LTAIVQAARCRFPQQAARNAYLFTQLGIH 210 L +VQAAR R+ Q AR+A LF +LGIH Sbjct: 193 LRTVVQAARLRYMAQKARHAELFVELGIH 221 >XF1503 [F] COG0194 Guanylate kinase Xfa Xylella fastidiosa 9a5c Length = 204 Score = 211 bits (537), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 103/199 (51%), Positives = 137/199 (68%) Query: 9 GSLFMVVAPSGAGKSTLVNALLKQEPSIKLSISYTTRAPRPGEEHGREYYFTDVDDFLKR 68 G+L++V A SG GKS++VNA L+++ I LSIS+T+R PRP E H + YYF D+F + Sbjct: 3 GTLYIVSAASGTGKSSIVNATLERDQQIALSISFTSRQPRPNERHAQHYYFVSADEFQRM 62 Query: 69 QAEGEFLEWAEVHGNYYGTSRLMIADQIANGTDVLLEIDWQGAQQVKKQFTNAIGIFILP 128 G+F E+A VH ++ GT+ + Q+A G DVLLEIDWQGA+QV+ + +AI IFILP Sbjct: 63 IEAGDFFEYALVHDDWKGTAHQSVEPQLAAGHDVLLEIDWQGARQVRNKIPDAISIFILP 122 Query: 129 PSIAALEERLKKRGQDEPHVITRRILAAGGEIAHSPEFEYVIINQEFAVALSELTAIVQA 188 PS AALEERL+KRGQD VI RR+ A E+AH EF+Y IIN+ F A+SE++AI A Sbjct: 123 PSRAALEERLRKRGQDSEEVIHRRLAAVHEEMAHYDEFDYTIINEHFETAVSEMSAIFTA 182 Query: 189 ARCRFPQQAARNAYLFTQL 207 +R R Q R+A L L Sbjct: 183 SRLRRQTQKVRHANLIRTL 201 >VC2708 [F] COG0194 Guanylate kinase Vch Vibrio cholerae Length = 229 Score = 208 bits (529), Expect = 7e-54, Method: Compositional matrix adjust. Identities = 101/201 (50%), Positives = 142/201 (70%), Gaps = 2/201 (0%) Query: 9 GSLFMVVAPSGAGKSTLVNALLKQEPS--IKLSISYTTRAPRPGEEHGREYYFTDVDDFL 66 G+L++V APSGAGKS+L+ ALL+Q P+ +K+S+S+TTR RPGE+ G Y+F + + F+ Sbjct: 26 GTLYIVSAPSGAGKSSLIAALLEQNPTYAMKVSVSHTTRGMRPGEQDGVHYHFVEKEHFI 85 Query: 67 KRQAEGEFLEWAEVHGNYYGTSRLMIADQIANGTDVLLEIDWQGAQQVKKQFTNAIGIFI 126 + +GEFLE+AEV GNYYGTSR+ I + + G DV L+IDWQGA+Q++ Q A IFI Sbjct: 86 ELIGKGEFLEYAEVFGNYYGTSRVWIENTLNKGIDVFLDIDWQGARQIRSQMPEAKSIFI 145 Query: 127 LPPSIAALEERLKKRGQDEPHVITRRILAAGGEIAHSPEFEYVIINQEFAVALSELTAIV 186 LPPS LE RL RGQD VI +R+ A EI+H E++YVIIN +F VAL + AI+ Sbjct: 146 LPPSKEELERRLNTRGQDSDAVIAKRMGEAKSEISHYSEYDYVIINDDFDVALMDFKAII 205 Query: 187 QAARCRFPQQAARNAYLFTQL 207 +A R + +QAA+ + + + L Sbjct: 206 RAERLKQDKQAAKYSAMLSAL 226 >STM3740 [F] COG0194 Guanylate kinase Sty Salmonella typhimurium LT2 Length = 207 Score = 207 bits (526), Expect = 2e-53, Method: Compositional matrix adjust. Identities = 100/201 (49%), Positives = 137/201 (68%), Gaps = 2/201 (0%) Query: 9 GSLFMVVAPSGAGKSTLVNALLKQEP--SIKLSISYTTRAPRPGEEHGREYYFTDVDDFL 66 G+L++V APSGAGKS+L+ ALLK +P ++S+S+TTRAPRPGE HG Y+F + D+F Sbjct: 4 GTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRAPRPGEVHGEHYFFVNHDEFK 63 Query: 67 KRQAEGEFLEWAEVHGNYYGTSRLMIADQIANGTDVLLEIDWQGAQQVKKQFTNAIGIFI 126 FLE AEV GNYYGTSR I +A G DV L+IDWQGAQQ++++ A IFI Sbjct: 64 TMIGREAFLEHAEVFGNYYGTSRETIEQVLATGVDVFLDIDWQGAQQIREKMPQARSIFI 123 Query: 127 LPPSIAALEERLKKRGQDEPHVITRRILAAGGEIAHSPEFEYVIINQEFAVALSELTAIV 186 LPPS L+ RL+ RGQD VI +R+ A E++H E++Y+I+N +F ALS+L I+ Sbjct: 124 LPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALSDLKTII 183 Query: 187 QAARCRFPQQAARNAYLFTQL 207 +A R R +Q R+ L ++L Sbjct: 184 RAERLRMSRQKQRHNALISKL 204 >gmk [F] COG0194 Guanylate kinase Eco Escherichia coli K12 Length = 207 Score = 206 bits (523), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 98/201 (48%), Positives = 139/201 (69%), Gaps = 2/201 (0%) Query: 9 GSLFMVVAPSGAGKSTLVNALLKQEP--SIKLSISYTTRAPRPGEEHGREYYFTDVDDFL 66 G+L++V APSGAGKS+L+ ALLK +P ++S+S+TTR PRPGE HG Y+F + D+F Sbjct: 4 GTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFK 63 Query: 67 KRQAEGEFLEWAEVHGNYYGTSRLMIADQIANGTDVLLEIDWQGAQQVKKQFTNAIGIFI 126 + + FLE AEV GNYYGTSR I +A G DV L+IDWQGAQQ++++ +A IFI Sbjct: 64 EMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFI 123 Query: 127 LPPSIAALEERLKKRGQDEPHVITRRILAAGGEIAHSPEFEYVIINQEFAVALSELTAIV 186 LPPS L+ RL+ RGQD VI +R+ A E++H E++Y+I+N +F AL++L I+ Sbjct: 124 LPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHYAEYDYLIVNDDFDTALTDLKTII 183 Query: 187 QAARCRFPQQAARNAYLFTQL 207 +A R R +Q R+ L ++L Sbjct: 184 RAERLRMSRQKQRHDALISKL 204