BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1975.p (418 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC1851 Non COG 187 4e-47 VC0137 Non COG 169 8e-42 BS_yuxH [T] COG3434 Predicted signal transduction protein contai... 168 2e-41 VC0515 Non COG 130 5e-30 aq_478 [T] COG3434 Predicted signal transduction protein contain... 103 1e-21 >VC1851 Non COG Length = 404 Score = 187 bits (475), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 126/392 (32%), Positives = 214/392 (54%), Gaps = 31/392 (7%) Query: 2 IGYELLFRSAAFGPANVKDDV---TATAAVIAHASELGLSNVIGNLHGFINVDAAVLMSD 58 IGYELLFR GP N D+ AT+ +++ + +G+L GF+N L++ Sbjct: 19 IGYELLFRD---GPKNTFPDIDPEEATSRLLSDHFLTAHYSTLGDLLGFVNFPYQSLLNM 75 Query: 59 FIYFLPADKVVLEILETVRVTPELVARVRELVKAGYVFALDDVVAESQEIEELLPLVKII 118 P +V+EILE TPEL++ ++++ + GY ALDD + S + + LP + II Sbjct: 76 VPTLFPVKSLVVEILEDCPPTPELLSAIKKMAQLGYKIALDDFIP-SNDWKAFLPYISII 134 Query: 119 KIDVMEVDPSKLLKLSVHFKRARK-ELLAEKVETLQQFNDCMTFGFDFFQGYYFAKPMIL 177 K D+ V P KL ++ R+ K E LAEKVET ++F GF +FQGY+F+KP I+ Sbjct: 135 KFDIRLV-PIPKAKLFINKLRSMKIEFLAEKVETYEEFEQAKQAGFHYFQGYFFSKPEII 193 Query: 178 QGKKLEASKMIIMHLLTLLVR-NVDNAEIVRYIKRDVALSLTLLRLVNTPVYGFQKFIDS 236 Q K L+ S + I+ LL + + VD EI + +D++LS LL VN+ K I S Sbjct: 194 QRKALQPSFLTIVQLLKEVAKPEVDFREIETIVAKDISLSYKLLTFVNSSATVSSK-IQS 252 Query: 237 LGQALIVLGRRQLKRWLQILLFANTDKERAHTMSPLMILAATRGKML-ELITAKIRPGRR 295 QAL+ LG+++L++++ ++ A+T + + L IL A +ML E + I PG Sbjct: 253 FRQALVYLGQQKLRKFISLVAIASTQDSKPDYLYNLAILRARFCEMLSERVPTNIAPG-- 310 Query: 296 KMSEMAFTVGIMSLVDALFGMSMESVLRQITVSTEIREALLRRNGYYGSVLRLVECTELR 355 F G+ S++D+L S++S+++++ + E+++AL + +G G +L L + E+ Sbjct: 311 ----TGFLTGMFSVLDSLLDQSLDSIVKEMPIEEEVKQALTQGSGTLGQILALNKAYEMA 366 Query: 356 E-------------PDQAEMQRLLDELQLSAD 374 + P++A + ++ ++ +AD Sbjct: 367 DWGQVVTLGQALNLPNEAPTECYIEAVKWTAD 398 >VC0137 Non COG Length = 432 Score = 169 bits (429), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 119/362 (32%), Positives = 189/362 (52%), Gaps = 21/362 (5%) Query: 2 IGYELLFRSA---AFGPANVKDDVTATAAVIAHASELGLSNVIGNLHGFINVDAAVLMSD 58 +GYELLFR AF P + D ++ + LG + I FIN L+ Sbjct: 43 LGYELLFRDGEKNAF-PEYMDADRATYRLIVENFLSLGTNPRIARSRCFINFPHKSLIRR 101 Query: 59 FIYFLPADKVVLEILETVRVTPELVARVRELVKAGYVFALDDVVAESQEIEELLPLVKII 118 LP +++V+EILET + T +L V+EL + GY+ ALDD V S E LP V+I+ Sbjct: 102 LPLTLPREQIVVEILETCQPTDDLFEAVQELSQRGYLLALDDFVY-SPAWERFLPYVQIV 160 Query: 119 KIDVMEVDPSKLLKLSVHFKR------ARKELLAEKVETLQQFNDCMTFGFDFFQGYYFA 172 KID+M + K + F R +R+ LAE+VET +F+ GF FFQGY+F+ Sbjct: 161 KIDIMAMGLDK----ACEFVRGRLAQGSRRRFLAERVETEDEFHQARHAGFTFFQGYFFS 216 Query: 173 KPMILQGKKLEASKMIIMHLLTLLVR-NVDNAEIVRYIKRDVALSLTLLRLVNTPVYGFQ 231 KP I++ + + +I M L + + VD + R + +D+ALS LLR VNT Sbjct: 217 KPEIIKQRYVSPEHVIAMQLFREVCQPEVDYVRVERLVAQDIALSYKLLRFVNTMSDRIS 276 Query: 232 KFIDSLGQALIVLGRRQLKRWLQILLFANTDKERAHTMSPLMILAATRGKMLELITAKIR 291 I S QAL+ LG+ +L+ ++ + + + ++ L L+ R + +L+ Sbjct: 277 VSISSFRQALVYLGQDKLRIFVSLAVASYISSKKPKE---LYNLSLQRAQFCQLMATHTH 333 Query: 292 PGRRKMSEMAFTVGIMSLVDALFGMSMESVLRQITVSTEIREALLRRNGYYGSVLRLVEC 351 + E AF +G+ S++DAL S+E ++ Q+ ++ +++ AL R G G++L L EC Sbjct: 334 --FKAHREQAFLIGMFSVLDALLDTSIEQLVEQLPLADDVKLALREREGPLGTLLDLEEC 391 Query: 352 TE 353 E Sbjct: 392 FE 393 >BS_yuxH [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains Bsu Bacillus subtilis Length = 409 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 111/398 (27%), Positives = 202/398 (50%), Gaps = 17/398 (4%) Query: 1 LIGYELLFRSAAFGPANVKD-DVTATAAVIAHASELGLSNVIGNLHGFINVDAAVLMSDF 59 ++ YELL+R + + KD D T VI +G+ + F+N +++ S+ Sbjct: 17 VVAYELLYRESEENVYSAKDGDQATTDLVINSFLNIGIEKLTEGKRCFVNFTESLMFSNL 76 Query: 60 IYFLPADKVVLEILETVRVTPELVARVRELVKAGYVFALDDVVAESQE----IEELLPLV 115 ++V+EILE + +TP L++R +EL K GY+ ALDD A + + +E+L+ + Sbjct: 77 PTSFNPKQLVIEILEDIPITPALISRCKELKKMGYMLALDDFYAINPQDEDLLEKLMSYI 136 Query: 116 KIIKIDVMEVDPSKLLKLSVHFKRARKELLAEKVETLQQFNDCMTFGFDFFQGYYFAKPM 175 I+KID ++ + + + LAEKVET +++ + GF FQGY+F++P Sbjct: 137 DILKIDFLKTTRMERRTILQTYGCRGLIFLAEKVETRKEYKQAVQDGFQLFQGYFFSEPR 196 Query: 176 ILQGKKLEASKMIIMHLLTLLVRNVDNAE-IVRYIKRDVALSLTLLRLVNTPVYGFQKFI 234 I+ G L LL L + N + + YI+RD++LS +L+ +N+ + I Sbjct: 197 IISGHDLSTHFYSYYELLNELSKEQPNIKRVTEYIERDLSLSYQILKFLNSSHSRLSQKI 256 Query: 235 DSLGQALIVLGRRQLKRWLQILLFANTDKERAHTMSPLMILAATRGKMLELITAKIRPGR 294 +S+ QA+++LG ++KRW+ IL F + ++ + ++ ++ R K+ EL+ R Sbjct: 257 ESIQQAIMLLGFNEIKRWIYILSFKDLSRKGHSSKHEIIKISLIRAKLCELLA---RKTS 313 Query: 295 RKMSEMAFTVGIMSLVDALFGMSMESVLRQITVSTEIREALLRRNGYYGSVLRLVECTEL 354 R +G+ SL+D L +E +++++ + E+ +ALL Y +L LV+ E Sbjct: 314 RPQPASYMLIGMFSLIDTLLHREIEEIVQELPLKDEVGQALLGHQNDYYQMLELVKLIES 373 Query: 355 REPDQAEMQRLLDEL--QLSADDFFAAEKHAFEWGNSI 390 D EL QL ++ + A EW +++ Sbjct: 374 NNWDTC------SELGNQLDKEEAYECYLEALEWCHNL 405 >VC0515 Non COG Length = 410 Score = 130 bits (327), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 111/358 (31%), Positives = 176/358 (49%), Gaps = 19/358 (5%) Query: 1 LIGYELLFRSAAFG--PANVKDDVTATAAVIAHASELGLSNVI-GNLHGFINVDAAVLMS 57 ++GYELLFR++ P V + + + + + V+ + FIN +L+ Sbjct: 17 IVGYELLFRNSEKNRYPEGVSESLATKKIIWQQFVDDTIDRVVESDKLCFINFPEDLLID 76 Query: 58 DFIYFLPADKVVLEILETVRVTPELVARVRELVKAGYVFALDDVVAESQE-IEELLPLVK 116 + LP DKVV+E+LE T +L++ +R L + GY+FALDDV E + L L Sbjct: 77 GYAEILPKDKVVIEVLENTIPTEKLLSVIRGLREKGYLFALDDVTRTVFENWHDYLSLFD 136 Query: 117 IIKIDVMEVDPSKLLKLSVHFKRARKELLAEKVETLQQFNDCMTFGFDFFQGYYFAKPMI 176 +KID +D LKL K LAEKVET +Q GF FQG+Y +P + Sbjct: 137 FVKIDTRRID-DDFLKLFFSLKPICCIALAEKVETNEQLESLKKNGFLLFQGFYLDRPKV 195 Query: 177 LQGKKLEASKMIIMHLLTLLV-RNVDNAEIVRYIKRDVALSLTLLRLVNT---PVYGFQK 232 L+ E + LL ++ R+ + + + + R+ L++ LL+ VNT P+ K Sbjct: 196 LRCATTEYANTESFELLIEVIKRDFNPSRLELILIRNPKLTVGLLKYVNTIGKPL----K 251 Query: 233 FIDSLGQALIVLGRRQLKRWLQILLFANTDKERAHTMSPLMILAATRGKMLELITAKIRP 292 I S+ A++ LG QL R LL ++T ++ + +L TR K EL+ +I Sbjct: 252 PISSIQHAIVYLGLEQL-RMFVFLLCSSTIHDKLDLDKYVYVL--TRAKFCELMMGEI-- 306 Query: 293 GRRKMSEMAFTVGIMSLVDALFGMSMESVLRQITVSTEIREALLRRNGYYGSVLRLVE 350 K+S MAF G++SL +L + +S ++R+A+L R G G V+ E Sbjct: 307 -DHKLSSMAFISGMLSLSHLFLPNDNSELLSSLPISNDMRDAVLCRAGILGDVISASE 363 >aq_478 [T] COG3434 Predicted signal transduction protein containing EAL and modified HD-GYP domains Aae Aquifex aeolicus Length = 411 Score = 103 bits (256), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 99/371 (26%), Positives = 181/371 (48%), Gaps = 28/371 (7%) Query: 34 ELGLSNVIGNLHGFINVDAAVLMSDFIYFLPADKVVLEIL-------ETVRVTPELVARV 86 E G+ + INV +++ + LP DKV+ ++ ET++ +++ ++ Sbjct: 52 ESGIEKLANGKKAVINVSLEAILNKSLELLPPDKVIFDLNPPEVPLGETLK--QKVLQKL 109 Query: 87 RELVKAGYVFALDDVVAESQEIEELLPLVKIIKIDVMEVDPSKLLKLSVHFKRARKELLA 146 ++ G F L++ + S E +EL+ L I++ V P K+ KR K++L Sbjct: 110 KDYKGKGVSFILNERLY-SSEHKELINLSDIVEFYFKSVTPDKIRSA----KRYGKKVLV 164 Query: 147 EKVETLQQFNDCMTFGFDFFQGYYFAKPMILQGKKLEAS-KMIIMHLLTLLVRNVDNAEI 205 +E +++ + +G D+FQG+YFAKP I++ KL K+ ++ LL + EI Sbjct: 165 SMIEKEEEYKKALEYGADYFQGFYFAKPEIVKRTKLAPFLKVTLLRLLNAISIARSLKEI 224 Query: 206 VRYIKRDVALSLTLLRLVNTPVYGFQKFIDSLGQALIVLGRRQLKRWLQILLFANTDKER 265 I+ DV L++ L+ VN+ + +K I+SL A+ +G +K+++ IL+ N E Sbjct: 225 ADIIETDVGLAVKFLQFVNSAYFARRKKIESLEHAVSFVGMENIKKFV-ILVSMN---EF 280 Query: 266 AHTMSP-LMILAATRGKMLELITAKIRPGRRKMSEMAFTVGIMSLVDALFGMSMESVLRQ 324 +P L + TR + E +T + P ++SE AF VG+ SL+D + + + + LR+ Sbjct: 281 LKVENPELWRKSLTRAFIAEELTNRYSP---EVSEKAFLVGLFSLLDKILEVDIPTFLRE 337 Query: 325 ITVSTEIREALLRRNGYYGSVLRLVECTEL---REPDQAE--MQRLLDELQLSADDFFAA 379 + V E+ +A + +L +V E P++ + Q+L EL + D Sbjct: 338 LNVDEEVVKAFEDKGSSLHKLLEVVSRLEEAVNSSPEELDKTAQQLSQELGIPEIDLVIV 397 Query: 380 EKHAFEWGNSI 390 K A E I Sbjct: 398 AKEAKEKAERI 408