BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1848.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VC0934 [M] COG2148 Sugar transferases involved in lipopolysaccha... 374 e-103 wcaJ [M] COG2148 Sugar transferases involved in lipopolysacchari... 341 2e-93 ZwcaJ [M] COG2148 Sugar transferases involved in lipopolysacchar... 338 1e-92 ECs2852 [M] COG2148 Sugar transferases involved in lipopolysacch... 338 1e-92 STM2103 [M] COG2148 Sugar transferases involved in lipopolysacch... 322 1e-87 >VC0934 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis Vch Vibrio cholerae Length = 465 Score = 374 bits (959), Expect = e-103, Method: Compositional matrix adjust. Identities = 200/442 (45%), Positives = 278/442 (62%), Gaps = 4/442 (0%) Query: 1 LIVAYLWVLVRLSHHIFNGDYWVLAIMAFFLSSYFFTEFHERRLRRNPRGPS-SFAPVLD 59 I+ +++ ++ + H+ Y +A++ SY R + S S Sbjct: 26 FILVIMYISIKSNQHVVTMSYISVALLGVLFYSYIAESLDIYSGWRTAKLRSLSLHTAFC 85 Query: 60 WLAVAAVLVVVAYICEFYQNLSMRAIFSWVVSTPIGLIISQHVQSRVMRDLHTKG-EVSK 118 W A A L ++AY + S + +W V + IGLI + + + +H KG Sbjct: 86 WAATIASLTLLAYFSKTGIEFSRMVMGAWFVGSFIGLIGWRVLAFATIHYMHKKGLHTKN 145 Query: 119 AIIIGVNPAALKLADRMEKYPSLMIKLMGFFDDRELNRQPPGTYTPLHGKMSDVAAYVRQ 178 A+IIG+ +L++ + K P L I + GF+DDR R G P+ G ++D + + Sbjct: 146 AVIIGMTTQGQELSNNLLKNPELGIVMQGFYDDRAPERLKEGA--PVLGNINDALSLAKT 203 Query: 179 NNINMVYISMPISAQPRVLQMIDELQDTTASIYFIPDIYIFNLIQARFDYVGGMAVMAIC 238 + VYI++P+ AQ R+ Q++D D+T + Y +PD + FNL+ +R+ +G + +I Sbjct: 204 GQVQNVYIALPMQAQRRINQILDAFSDSTVNTYIVPDFFTFNLLHSRWYTIGDVNAFSIF 263 Query: 239 ETPFTGTNNIVKRLSDLVLASGILLMLLPVMVVIAICVKLTSPGPIIFKQRRYGLDGEEI 298 +TPF G N VKR DLVL+S ILL++ PV++ +AI VKL+SPGPIIFKQ RYGLDG+ I Sbjct: 264 DTPFNGLLNWVKRFEDLVLSSLILLLISPVLLAVAIGVKLSSPGPIIFKQNRYGLDGKPI 323 Query: 299 VVYKFRSMTVMEDGGKVTQATKGDMRLTKIGGFLRSSSLDELPQFFNVLQGRMSIVGPRP 358 V+KFRSM VM++G V QATKGD R+T+ G F+R +SLDELPQFFNVLQG MSIVGPRP Sbjct: 324 QVWKFRSMRVMDNGSHVQQATKGDPRVTRFGAFIRRTSLDELPQFFNVLQGSMSIVGPRP 383 Query: 359 HAVAHNELYRKQIKGYMLRHKVKPGITGWAQVNGLRGETETLDKMKARIEFDLEYLRRWS 418 HAVAHNE YR + YMLRHKVKPGITGWAQ+NG RGET+TLDKM+ R++FDL+Y+ RWS Sbjct: 384 HAVAHNEQYRTIVNRYMLRHKVKPGITGWAQINGWRGETDTLDKMEKRVQFDLDYIHRWS 443 Query: 419 LVFDLWIIFQTVRMVIKRDNAY 440 L FDL I+F T+ NAY Sbjct: 444 LWFDLKIVFLTIFKGFVGKNAY 465 >wcaJ [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis Eco Escherichia coli K12 Length = 464 Score = 341 bits (874), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 185/435 (42%), Positives = 276/435 (63%), Gaps = 13/435 (2%) Query: 1 LIVAYLWVLVRLSHHIFNGDYWVLAIMAFFLSSYF--FTEFHERRLRRNPRGPSSFAPVL 58 ++ A LW++ +S F + ++A++ + T+F+ R R R + FA +L Sbjct: 28 IMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFY--RSWRGVRAATEFALLL 85 Query: 59 -DW-LAVAAVLVVVAYICEFYQNLSMRAIFSWVVSTPIGLIISQHVQSRVMRDLHTKGEV 116 +W L+V +VA+ +F + ++ +W T IGL++ + L G Sbjct: 86 QNWTLSVIFSAGLVAFNNDF--DTQLKIWLAWYALTSIGLVVCRSCIRIGAGWLRNHGYN 143 Query: 117 SKAIIIGVNPAALK-LADRMEKYPSLMIKLMGFFDDRELNRQPPGTYTPLHGKMSDVAAY 175 + + + + AA + L + P L +++G + D +P G G + + Sbjct: 144 KRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDP----KPGGVSNDWAGNLQQLVED 199 Query: 176 VRQNNINMVYISMPISAQPRVLQMIDELQDTTASIYFIPDIYIFNLIQARFDYVGGMAVM 235 + I+ VYI+M + RV +++ +L DTT S+ IPD++ FN++ +R + + G+ V+ Sbjct: 200 AKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVV 259 Query: 236 AICETPFTGTNNIVKRLSDLVLASGILLMLLPVMVVIAICVKLTSPGPIIFKQRRYGLDG 295 + +TP +G N ++KR D+VLA+ ILL++ PV+ IA+ VKL+SPGP+IF+Q RYG+DG Sbjct: 260 PLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDG 319 Query: 296 EEIVVYKFRSMTVMEDGGKVTQATKGDMRLTKIGGFLRSSSLDELPQFFNVLQGRMSIVG 355 + I V+KFRSM VME+ VTQAT+ D R+TK+G FLR +SLDELPQF NVL G MSIVG Sbjct: 320 KPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVG 379 Query: 356 PRPHAVAHNELYRKQIKGYMLRHKVKPGITGWAQVNGLRGETETLDKMKARIEFDLEYLR 415 PRPHAVAHNE YR+ I+GYMLRHKVKPGITGWAQ+NG RGET+TL+KM+ R+EFDLEY+R Sbjct: 380 PRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIR 439 Query: 416 RWSLVFDLWIIFQTV 430 WS+ FD+ I+F TV Sbjct: 440 EWSVWFDIKIVFLTV 454 >ZwcaJ [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis EcZ Escherichia coli O157:H7 EDL933 Length = 464 Score = 338 bits (868), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 185/435 (42%), Positives = 276/435 (63%), Gaps = 13/435 (2%) Query: 1 LIVAYLWVLVRLSHHIFNGDYWVLAIMAFFLSSYF--FTEFHERRLRRNPRGPSSFAPVL 58 ++ A LW++ +S F + ++A++ + T+F+ R R R + FA +L Sbjct: 28 IMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFY--RSWRGVRAATEFALLL 85 Query: 59 -DW-LAVAAVLVVVAYICEFYQNLSMRAIFSWVVSTPIGLIISQHVQSRVMRDLHTKGEV 116 +W L+V +VA+ +F + ++ +W T IGL++ + L G Sbjct: 86 QNWTLSVIFSAGLVAFNNDF--DTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYN 143 Query: 117 SKAIIIGVNPAALK-LADRMEKYPSLMIKLMGFFDDRELNRQPPGTYTPLHGKMSDVAAY 175 + + + + AA + L + P L +++G + D +L G G + + Sbjct: 144 KRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDPKLG----GVSNDWAGNLQQLVED 199 Query: 176 VRQNNINMVYISMPISAQPRVLQMIDELQDTTASIYFIPDIYIFNLIQARFDYVGGMAVM 235 + I+ VYI+M + RV +++ +L DTT S+ IPD++ FN++ +R + + G+ V+ Sbjct: 200 AKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVV 259 Query: 236 AICETPFTGTNNIVKRLSDLVLASGILLMLLPVMVVIAICVKLTSPGPIIFKQRRYGLDG 295 + +TP +G N ++KR D+VLA+ ILL++ PV+ IA+ VKL+SPGP+IF+Q RYG+DG Sbjct: 260 PLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDG 319 Query: 296 EEIVVYKFRSMTVMEDGGKVTQATKGDMRLTKIGGFLRSSSLDELPQFFNVLQGRMSIVG 355 + I V+KFRSM VME+ VTQAT+ D R+TK+G FLR +SLDELPQF NVL G MSIVG Sbjct: 320 KPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVG 379 Query: 356 PRPHAVAHNELYRKQIKGYMLRHKVKPGITGWAQVNGLRGETETLDKMKARIEFDLEYLR 415 PRPHAVAHNE YR+ I+GYMLRHKVKPGITGWAQ+NG RGET+TL+KM+ R+EFDLEY+R Sbjct: 380 PRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIR 439 Query: 416 RWSLVFDLWIIFQTV 430 WS+ FD+ I+F TV Sbjct: 440 EWSVWFDIKIVFLTV 454 >ECs2852 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis Ecs Escherichia coli O157:H7 Length = 464 Score = 338 bits (868), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 185/435 (42%), Positives = 276/435 (63%), Gaps = 13/435 (2%) Query: 1 LIVAYLWVLVRLSHHIFNGDYWVLAIMAFFLSSYF--FTEFHERRLRRNPRGPSSFAPVL 58 ++ A LW++ +S F + ++A++ + T+F+ R R R + FA +L Sbjct: 28 IMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFY--RSWRGVRAATEFALLL 85 Query: 59 -DW-LAVAAVLVVVAYICEFYQNLSMRAIFSWVVSTPIGLIISQHVQSRVMRDLHTKGEV 116 +W L+V +VA+ +F + ++ +W T IGL++ + L G Sbjct: 86 QNWTLSVIFSAGLVAFNNDF--DTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYN 143 Query: 117 SKAIIIGVNPAALK-LADRMEKYPSLMIKLMGFFDDRELNRQPPGTYTPLHGKMSDVAAY 175 + + + + AA + L + P L +++G + D +L G G + + Sbjct: 144 KRMVAVAGDLAAGQMLMESFRNQPWLGFEVVGVYHDPKLG----GVSNDWAGNLQQLVED 199 Query: 176 VRQNNINMVYISMPISAQPRVLQMIDELQDTTASIYFIPDIYIFNLIQARFDYVGGMAVM 235 + I+ VYI+M + RV +++ +L DTT S+ IPD++ FN++ +R + + G+ V+ Sbjct: 200 AKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDVFTFNILHSRLEEMNGVPVV 259 Query: 236 AICETPFTGTNNIVKRLSDLVLASGILLMLLPVMVVIAICVKLTSPGPIIFKQRRYGLDG 295 + +TP +G N ++KR D+VLA+ ILL++ PV+ IA+ VKL+SPGP+IF+Q RYG+DG Sbjct: 260 PLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDG 319 Query: 296 EEIVVYKFRSMTVMEDGGKVTQATKGDMRLTKIGGFLRSSSLDELPQFFNVLQGRMSIVG 355 + I V+KFRSM VME+ VTQAT+ D R+TK+G FLR +SLDELPQF NVL G MSIVG Sbjct: 320 KPIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVG 379 Query: 356 PRPHAVAHNELYRKQIKGYMLRHKVKPGITGWAQVNGLRGETETLDKMKARIEFDLEYLR 415 PRPHAVAHNE YR+ I+GYMLRHKVKPGITGWAQ+NG RGET+TL+KM+ R+EFDLEY+R Sbjct: 380 PRPHAVAHNEQYRQLIEGYMLRHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIR 439 Query: 416 RWSLVFDLWIIFQTV 430 WS+ FD+ I+F TV Sbjct: 440 EWSVWFDIKIVFLTV 454 >STM2103 [M] COG2148 Sugar transferases involved in lipopolysaccharide synthesis Sty Salmonella typhimurium LT2 Length = 464 Score = 322 bits (824), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 168/363 (46%), Positives = 240/363 (66%), Gaps = 7/363 (1%) Query: 69 VVAYICEFYQNLSMRAIFSWVVSTPIGLIISQHVQSRVMRDLHTKG-EVSKAIIIGVNPA 127 +VA+ +F L+ +W + +GL++ + L +G + + G PA Sbjct: 98 LVAFNDDFDNRLA--TWLAWYALSSLGLVLCRSFIRFGAGWLRNRGYNTRRVAVAGDLPA 155 Query: 128 ALKLADRMEKYPSLMIKLMGFFDDRELNRQPPGTYTPLHGKMSDVAAYVRQNNINMVYIS 187 L D P L +++G + D +P G G + + + I+ VYI+ Sbjct: 156 GQALLDSFRNEPWLGFEVVGVYHDP----KPGGVSADWAGNFEQLIDDAKASRIHNVYIA 211 Query: 188 MPISAQPRVLQMIDELQDTTASIYFIPDIYIFNLIQARFDYVGGMAVMAICETPFTGTNN 247 M +S V +++ EL DTT S+ IPD++ FN++ +R + + G+ V+ + +TP +G N Sbjct: 212 MSMSDGAMVKKLVRELADTTCSVILIPDVFTFNILHSRVEEMSGVPVVPLYDTPLSGINR 271 Query: 248 IVKRLSDLVLASGILLMLLPVMVVIAICVKLTSPGPIIFKQRRYGLDGEEIVVYKFRSMT 307 ++KR D+VLAS ILL++ PV+ IA+ VKL+SPGP+IF+Q RYG+DG+ I V+KFRSM Sbjct: 272 LLKRAEDIVLASLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGKPIKVWKFRSMK 331 Query: 308 VMEDGGKVTQATKGDMRLTKIGGFLRSSSLDELPQFFNVLQGRMSIVGPRPHAVAHNELY 367 VME+ VTQAT+ D R+T++G FLR +SLDELPQF NVL G MSIVGPRPHAVAHNE Y Sbjct: 332 VMENDKVVTQATQNDPRVTRVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQY 391 Query: 368 RKQIKGYMLRHKVKPGITGWAQVNGLRGETETLDKMKARIEFDLEYLRRWSLVFDLWIIF 427 R+ I+GYMLRHK+KPGITGWAQ+NG RGET+TL+KM+ R+EFDLEY+R WS+ FD+ I+F Sbjct: 392 RQLIEGYMLRHKMKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSIWFDIKIVF 451 Query: 428 QTV 430 T+ Sbjct: 452 LTI 454