BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1809.p (621 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex... 913 0.0 NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex... 629 e-180 NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex... 615 e-175 PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex ... 575 e-164 XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex ... 530 e-150 >RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex Rso Ralstonia solanacearum Length = 654 Score = 913 bits (2359), Expect = 0.0, Method: Compositional matrix adjust. Identities = 458/649 (70%), Positives = 518/649 (79%), Gaps = 29/649 (4%) Query: 2 SELPASPLPDPREVVLET---VARLPHLPGVYRYFDADDNVLYVGKARDLKKRVSSYFQK 58 ++ P +P DP E + +ARLP LPGVYRYFDA +VLYVGKARDLKKRVSSYF K Sbjct: 6 AQTPPAPAVDPSEAAFDAKAHIARLPSLPGVYRYFDAQGSVLYVGKARDLKKRVSSYFTK 65 Query: 59 TLTSPRIAMMVERIARLETTVTRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKLTG 118 TL SPRIAMMV +IA +ETTV RSEAEALLLENNLIK L PR+NILFRDDKSYPYLKLT Sbjct: 66 TLLSPRIAMMVAKIAHIETTVVRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTQ 125 Query: 119 HAFPRMAYYRGAVDKRNQYFGPFPNAGAVKESIQILQKVFRLRTCEDTVFANRTRPCLLH 178 HA+PRMAYYRGA D+++QYFGPFP+A AV+ES+QILQKVF+LRTCEDTVF NRTRPCLLH Sbjct: 126 HAYPRMAYYRGATDRKHQYFGPFPSAHAVRESMQILQKVFQLRTCEDTVFNNRTRPCLLH 185 Query: 179 QIHRCSGPCVNLVSSEDYAIDVENAAKFLRGRQSEVMQALEQKMHAFAADLKFEQAAAVR 238 QIHRC+ PCV +S+EDYA DV NAA FL GRQ EVMQ L+ KM AA L+FEQAA VR Sbjct: 186 QIHRCTAPCVQAISAEDYARDVANAAGFLLGRQDEVMQTLQDKMQRHAAALEFEQAATVR 245 Query: 239 DQIGSLSSVLHQQSMETVSDA-DIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVD 297 DQIG+LS+VL +QS+E V A DIDI+AV ++GG ACVNLAMVRGGRHLGD+AYFPTHV+ Sbjct: 246 DQIGALSTVLTRQSVEEVGQASDIDILAVAIKGGHACVNLAMVRGGRHLGDKAYFPTHVE 305 Query: 298 DAMDTAEDSIEVEV---------------------LKAFLAQHYIDKFIPGSLIVGTEFD 336 + +E +V L+AF+AQHY+D+F+P L+V Sbjct: 306 EGAAIVGVDVEADVPEGAETQPEPARDPERMARDILEAFVAQHYLDQFVPPVLVVSHPIR 365 Query: 337 DPALMLALMEQCGHRIALTFQPQGQRRQWLEMAAKGAEIALARLLSEQGSQQARTRALAE 396 L+ AL Q G R+++ QPQG RR WLEMA KGAE++LAR LSEQGSQQARTRALAE Sbjct: 366 AAGLIEALAAQAGRRVSVVRQPQGARRAWLEMAEKGAELSLARRLSEQGSQQARTRALAE 425 Query: 397 VLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYRRYNINDITPGDDYAA 456 + ++ EDL LR ECFDISHT GEATQASCVVFH HAMQNGEYRRYNI DI PGDDYAA Sbjct: 426 TIGVDLEDLAALRVECFDISHTAGEATQASCVVFHSHAMQNGEYRRYNIQDIIPGDDYAA 485 Query: 457 MRQVLTRRYEKV----ANGEGVMPDIVLIDGGRGQVEMARQVLTELGLDISLIVGVAKGE 512 MRQVLTRRY+KV A MP +VLIDGG+GQVE+ARQV ELGLDI L+VGVAKGE Sbjct: 486 MRQVLTRRYQKVVEQAAEDAPDMPRVVLIDGGKGQVEVARQVFEELGLDIGLLVGVAKGE 545 Query: 513 GRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKRAKARQSSRLEE 572 GRKVGLETLVFADGR ELG+ SAALML+AQIRDEAHRFAITGMRAKRAKAR +SRLEE Sbjct: 546 GRKVGLETLVFADGRPSLELGQGSAALMLVAQIRDEAHRFAITGMRAKRAKARNTSRLEE 605 Query: 573 IEGIGAKRRQRLLVRFGGLRGVADASVDELASVEGISRQLAEEIYRQLH 621 IEGIGAKRRQRLL RFGGLRGV ASV+ELA+VEGIS+ LAEEIYRQLH Sbjct: 606 IEGIGAKRRQRLLARFGGLRGVMAASVEELATVEGISQTLAEEIYRQLH 654 >NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex NmA Neisseria meningitidis Z2491 Length = 628 Score = 629 bits (1622), Expect = e-180, Method: Compositional matrix adjust. Identities = 325/610 (53%), Positives = 419/610 (68%), Gaps = 17/610 (2%) Query: 20 VARLPHLPGVYRYFDADDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 79 + LP LPGVYR+FD VLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 28 LKNLPKLPGVYRFFDEGGKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 87 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKLTGHAFPRMAYYRGAVDKRNQYFG 139 TRSEAEAL+LENN IK L P++NILFRDDKSYPYL L+GH +P+MAYYRG + K NQYFG Sbjct: 88 TRSEAEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 147 Query: 140 PFPNAGAVKESIQILQKVFRLRTCEDTVFANRTRPCLLHQIHRCSGPCVNLVSSEDYAID 199 P+PN+ AV++SIQILQKVF LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 148 PYPNSNAVRDSIQILQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 207 Query: 200 VENAAKFLRGRQSEVMQALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETV--- 256 V AA FL G+ E+ + L+ KM AA+L+FE+AA RDQI +L + Q +++ Sbjct: 208 VRQAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 267 Query: 257 SDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIEVEVLKAFL 316 + DID++A+ V G CV+ +RGGRH+GD+++FP +D +D E AF+ Sbjct: 268 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 322 Query: 317 AQHYIDKFIPGSLIVGTEFDDPALMLALMEQCGHRIALTFQPQGQRRQWLEMAAKGAEIA 376 AQHY+ K P +I D AL AL + G ++ + G+R+ WL+MA + A++A Sbjct: 323 AQHYLGKSKPDIIINNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVWLKMAEQNAQMA 381 Query: 377 LARLLSEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q +QQ R LA++L ++ + L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 382 IAQRRLQQSNQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 439 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGV-MPDIVLIDGGRGQVEMA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V PD VLIDGG+GQ+ +A Sbjct: 440 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGIA 499 Query: 492 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 551 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 500 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 558 Query: 552 FAITGMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDELASVEGISRQ 611 FAITG R KR KAR +S L +I G+G+KRRQ LL RFGGLRGV AS ++L VEGIS+ Sbjct: 559 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 618 Query: 612 LAEEIYRQLH 621 LAE IY LH Sbjct: 619 LAETIYEHLH 628 >NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex Nme Neisseria meningitidis MC58 Length = 617 Score = 615 bits (1586), Expect = e-175, Method: Compositional matrix adjust. Identities = 323/610 (52%), Positives = 420/610 (68%), Gaps = 17/610 (2%) Query: 20 VARLPHLPGVYRYFDADDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 79 + LP+LPGVYR+F+ NVLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 17 LKNLPNLPGVYRFFNESGNVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 76 Query: 80 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKLTGHAFPRMAYYRGAVDKRNQYFG 139 TRSE+EAL+LENN IK L P++NILFRDDKSYPYL L+GH +P+MAYYRG + K NQYFG Sbjct: 77 TRSESEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 136 Query: 140 PFPNAGAVKESIQILQKVFRLRTCEDTVFANRTRPCLLHQIHRCSGPCVNLVSSEDYAID 199 P+PN+ AV++SIQ+LQKVF LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 137 PYPNSNAVRDSIQVLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 196 Query: 200 VENAAKFLRGRQSEVMQALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETV--- 256 V AA FL G+ E+ + L+ KM AA+L+FE+AA RDQI +L + Q +++ Sbjct: 197 VREAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 256 Query: 257 SDADIDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIEVEVLKAFL 316 + DID++A+ V G CV+ +RGGRH+GD+++FP +D +D E AF+ Sbjct: 257 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 311 Query: 317 AQHYIDKFIPGSLIVGTEFDDPALMLALMEQCGHRIALTFQPQGQRRQWLEMAAKGAEIA 376 AQHY+ K P +I D AL AL + G ++ + G+R+ L+MA + A++A Sbjct: 312 AQHYLGKSKPDIIISNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVRLKMAEQNAQMA 370 Query: 377 LARLLSEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 436 +A+ +Q SQQ R LA++L ++ + L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 371 IAQRRLQQSSQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 428 Query: 437 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGV-MPDIVLIDGGRGQVEMA 491 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V PD VLIDGG+GQ+ +A Sbjct: 429 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGVA 488 Query: 492 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 551 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 489 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 547 Query: 552 FAITGMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDELASVEGISRQ 611 FAITG R KR KAR +S L +I G+G+KRRQ LL RFGGLRGV AS ++L VEGIS+ Sbjct: 548 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 607 Query: 612 LAEEIYRQLH 621 LAE IY LH Sbjct: 608 LAETIYNHLH 617 >PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex Pae Pseudomonas aeruginosa Length = 608 Score = 575 bits (1483), Expect = e-164, Method: Compositional matrix adjust. Identities = 303/600 (50%), Positives = 405/600 (67%), Gaps = 16/600 (2%) Query: 27 PGVYRYFDADDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEA 86 PGVYR FDA+ +LYVGKA+ LKKR++SYF+K+ +P+ A +V RIA++ETT+T +E EA Sbjct: 18 PGVYRMFDAEAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTITANETEA 77 Query: 87 LLLENNLIKTLRPRFNILFRDDKSYPYLKLTGH-AFPRMAYYRGAVDKRNQYFGPFPNAG 145 LLLE LIK RP +NIL RDDKSYP++ L+ +PR++ +RGA ++ +YFGP+P+AG Sbjct: 78 LLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAG 137 Query: 146 AVKESIQILQKVFRLRTCEDTVFANRTRPCLLHQIHRCSGPCVNLVSSEDYAIDVENAAK 205 A++ES+ +LQK F +R CED+ F NRTRPCL +QI RC GPCV LVS E+YA DV ++ Sbjct: 138 AIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAEDVRHSVM 197 Query: 206 FLRGRQSEVMQALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIA 265 FL GR + + L M A L FE+AA +RDQ+ L V QQSME + D+DI+A Sbjct: 198 FLEGRSNALADELNVGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSMEG-GNGDVDIVA 256 Query: 266 VVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIEVEVLKAFLAQHYI---D 322 +V G ACV+L VRGGR LG + +FP A + EVL AFL Q+Y+ + Sbjct: 257 AIVTPGGACVHLISVRGGRVLGSKNFFP-------QVAIEEEVGEVLLAFLGQYYLSHQE 309 Query: 323 KFIPGSLIVGTEFDD-PALMLALMEQCGHRIALTFQPQGQRRQWLEMAAKGAEIALARLL 381 + +P LIV +D P L+ A+ E G + ++++ +G R +W ++A AE AL L Sbjct: 310 RDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTNAEQALGARL 369 Query: 382 SEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYR 441 + + AR ALAE L+L R ECFDISH+ GEAT ASCVVF +YR Sbjct: 370 ANRQHVAARFEALAEALDLAEPPQ---RLECFDISHSSGEATVASCVVFGPEGPLKSDYR 426 Query: 442 RYNINDITPGDDYAAMRQVLTRRYEKVANGEGVMPDIVLIDGGRGQVEMARQVLTELGLD 501 RYNI +T GDDYAAM Q LTRR+ ++ +GEG MPDI+L+DGG+GQ+ MA++VL EL + Sbjct: 427 RYNIEGVTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEVLQELAVA 486 Query: 502 ISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKR 561 +++GVAKG RK GLETL D L +S AL LI QIRDEAHRFAITG RA+R Sbjct: 487 GLILLGVAKGVTRKPGLETLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAITGHRARR 546 Query: 562 AKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDELASVEGISRQLAEEIYRQLH 621 KAR++S LE++ G+G KRR+ LL FGGL+ ++ AS+DELA GIS++LAE+IY LH Sbjct: 547 GKARRTSTLEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAEQIYAVLH 606 >XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex Xfa Xylella fastidiosa 9a5c Length = 627 Score = 530 bits (1366), Expect = e-150, Method: Compositional matrix adjust. Identities = 282/606 (46%), Positives = 394/606 (65%), Gaps = 19/606 (3%) Query: 21 ARLPHLPGVYRYFDADDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVT 80 A L PGVY + ADD +LYVGKA L+KRV+SYF T + R+ M+ ++ R++ T+T Sbjct: 22 AHLSMAPGVYCMYAADDTLLYVGKAGALRKRVASYFNGTPKNTRLTAMLAQVVRMDVTIT 81 Query: 81 RSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKLTGHAFPRMAYYRGAVDKRNQYFGP 140 R+EAEALLLEN LIK+L PR+N+L RDDKSYPY+ LT A+PR+A +RG +YFGP Sbjct: 82 RNEAEALLLENQLIKSLAPRYNVLLRDDKSYPYVLLTREAWPRIALHRGPQIVPGRYFGP 141 Query: 141 FPNAGAVKESIQILQKVFRLRTCEDTVFANRTRPCLLHQIHRCSGPCVNLVSSEDYAIDV 200 +P AV++ + ++ K+F+LR+CED+VF NR+RPCL +QI RCS PCVN+V+ ++Y V Sbjct: 142 YPGVTAVRDMLNLIHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVNVVTHDNYTEAV 201 Query: 201 ENAAKFLRGRQSEVMQALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDAD 260 FL G+ + + L Q M + L+FEQAA +RD + SL S+ ++Q ++ + AD Sbjct: 202 RRVTLFLEGKSDLLAEELIQAMQVASEHLEFEQAARLRDLLTSLRSMQNRQYVDGRA-AD 260 Query: 261 IDIIAVVVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEDSIEVEVLKAFLAQHY 320 +D++A G ACV L R GR+LG R +FP T + E+L AF++Q+Y Sbjct: 261 LDVLACAALSGHACVLLLSFRDGRNLGTRMFFP-------KTNGEERTAEILSAFVSQYY 313 Query: 321 IDKFIPGSLIVGTEFDDPALM-LALMEQCGHRIALTFQPQGQRRQWLEMAAKGAEIALAR 379 + P +++ E D L+ A H+I+L + +G+R ++E+A + A++AL+ Sbjct: 314 AEYPPPPEILLDQEIPDHTLLEAAFSRSSAHKISLRWNVRGERAGYVELAVRNAQVALST 373 Query: 380 LLSEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGE 439 L+ Q +Q+ R+ A+ ++L LE E + R ECFDISHT GEAT ASCVVF + Sbjct: 374 ELTSQRAQRVRSEAVRQLLGLE-EPIK--RVECFDISHTMGEATVASCVVFDAVGPVRSQ 430 Query: 440 YRRYNINDITPGDDYAAMRQVLTRRYEKVA--NGEGVMPDIVLIDGGRGQVEMARQVLTE 497 YRRYNI ITPGDDYAAMRQ + RR+ + + +G PD++ IDGG GQ+ A+ L Sbjct: 431 YRRYNITGITPGDDYAAMRQAIERRFRRAVEEDKQGERPDVLFIDGGAGQLAQAKMALNA 490 Query: 498 LGLDISLIVGVAKGEGRKVGLETLVFADGRAPKEL--GKESAALMLIAQIRDEAHRFAIT 555 +G++ L+VGV+KGE R+ G ETL+ DG +EL G S AL I Q+RDEAHRFAIT Sbjct: 491 VGVESVLLVGVSKGEERRAGHETLIMLDG---QELHPGAASPALQFIQQVRDEAHRFAIT 547 Query: 556 GMRAKRAKARQSSRLEEIEGIGAKRRQRLLVRFGGLRGVADASVDELASVEGISRQLAEE 615 G RA+R K R +S+LE+I GIG++RR LL FGGL GV A E+A VEGIS LA + Sbjct: 548 GHRARRQKTRMTSKLEDIPGIGSRRRANLLKHFGGLAGVKAAGQTEIARVEGISTALAAK 607 Query: 616 IYRQLH 621 IY LH Sbjct: 608 IYASLH 613