BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1779.p (433 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2337 [J] COG0172 Seryl-tRNA synthetase Rso Ralstonia solanace... 682 0.0 NMB1684 [J] COG0172 Seryl-tRNA synthetase Nme Neisseria meningit... 620 e-177 NMA1943 [J] COG0172 Seryl-tRNA synthetase NmA Neisseria meningit... 614 e-175 PA2612 [J] COG0172 Seryl-tRNA synthetase Pae Pseudomonas aeruginosa 569 e-162 STM0963 [J] COG0172 Seryl-tRNA synthetase Sty Salmonella typhimu... 556 e-158 >RSc2337 [J] COG0172 Seryl-tRNA synthetase Rso Ralstonia solanacearum Length = 438 Score = 682 bits (1761), Expect = 0.0, Method: Compositional matrix adjust. Identities = 335/436 (76%), Positives = 365/436 (83%), Gaps = 5/436 (1%) Query: 1 MIDIQLLRKDIDNVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+DIQLLRKDID VAARL R + LDVAGF ALEAERK IQTRTEELQ +RNSLSKQIGM Sbjct: 1 MLDIQLLRKDIDAVAARLNDRGYELDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGM 60 Query: 61 LKGKGEDASAVMAEVNGIGDELKASATRLDEVQQQMTLFLQAVPNLPHESVPVGNDENGN 120 LKGKGEDASAVMAEV GIGDELKASA +LD VQ ++ L ++PN+PHESVP G E N Sbjct: 61 LKGKGEDASAVMAEVAGIGDELKASAAQLDVVQGRLQDLLLSIPNVPHESVPAGKSEAEN 120 Query: 121 VELRKVGTPRQFDFEIKDHVDVGAPLGLDFDTATKLTGSRFAVLKGGIARLHRALAQFML 180 VE+R+ GTPR FDF +KDHVD+GA LGLDFD A KL+GSRFAVLKG +ARLHRALAQFML Sbjct: 121 VEVRREGTPRAFDFPVKDHVDLGAGLGLDFDVAAKLSGSRFAVLKGPVARLHRALAQFML 180 Query: 181 NTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLF-AAKKGGQEGEAENAA----LYL 235 +THT EHGYTE Y PYIVNA S+RGTGQLPKFE DLF +K GQ EAE YL Sbjct: 181 DTHTQEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGQATEAEAGEHVENFYL 240 Query: 236 IPTAEVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQ 295 IPTAEVPLTN VRDEIVAGDALPMKF AHSPCFRSEAGSYG+DTRGMIRQHQFDKVEMVQ Sbjct: 241 IPTAEVPLTNLVRDEIVAGDALPMKFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQ 300 Query: 296 IVHPEQSYAALEEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYR 355 IV PE S+ AL+ M HAE IL+KL LP+R + LCTGDMGFG+ KTYDIEVW+PAQNTYR Sbjct: 301 IVQPETSFEALDAMTHHAENILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYR 360 Query: 356 EISSVSNCEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDI 415 EISS SN FQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQ ADGSV + Sbjct: 361 EISSCSNMGDFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQNADGSVTV 420 Query: 416 PEVLQPYMGGVSKLVP 431 P L+PY+GG + L P Sbjct: 421 PAALRPYLGGQAVLKP 436 >NMB1684 [J] COG0172 Seryl-tRNA synthetase Nme Neisseria meningitidis MC58 Length = 431 Score = 620 bits (1600), Expect = e-177, Method: Compositional matrix adjust. Identities = 295/431 (68%), Positives = 348/431 (80%), Gaps = 5/431 (1%) Query: 1 MIDIQLLRKDIDNVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+DIQLLR + VA RLA R + D A F+ LE RK +Q +TEELQ RNS+SKQIG Sbjct: 1 MLDIQLLRSNTAAVAERLARRGYDFDTARFDTLEERRKSVQVKTEELQASRNSISKQIGA 60 Query: 61 LKGKG--EDASAVMAEVNGIGDELKASATRLDEVQQQMTLFLQAVPNLPHESVPVGNDEN 118 LKG+G E+A A M +V I +L+ +A LD VQ+++ +L ++PNLPHESVP G DE Sbjct: 61 LKGQGKHEEAQAAMNQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPAGKDET 120 Query: 119 GNVELRKVGTPRQFDFEIKDHVDVGAPLGLDFDTATKLTGSRFAVLKGGIARLHRALAQF 178 NVE+RKVGTPR+FDFEIKDHVD+G PLGLDF+ KL+G+RF V++G IARLHRALAQF Sbjct: 121 ENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQF 180 Query: 179 MLNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPT 238 ML+THT++HGYTE YTPYIV+ +L+GTGQLPKF DLF +GG E + YLIPT Sbjct: 181 MLDTHTLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQ---YLIPT 237 Query: 239 AEVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVH 298 AEV LTN V D I+ + LP+K TAHSPCFRSEAGSYG+DTRG+IRQHQFDKVEMVQIVH Sbjct: 238 AEVTLTNTVADSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVH 297 Query: 299 PEQSYAALEEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREIS 358 PE+SY LEEM+GHAE ILK L LPYRVITLCTGDMGFGAAKTYD+EVW+PAQNTYREIS Sbjct: 298 PEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFGAAKTYDLEVWVPAQNTYREIS 357 Query: 359 SVSNCEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEV 418 S SNCE FQARR++ARF++ GK L+HTLNGSGLAVGRTLVAVLEN+Q ADGS++IP Sbjct: 358 SCSNCEDFQARRLKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAA 417 Query: 419 LQPYMGGVSKL 429 LQPYMGGV+KL Sbjct: 418 LQPYMGGVAKL 428 >NMA1943 [J] COG0172 Seryl-tRNA synthetase NmA Neisseria meningitidis Z2491 Length = 431 Score = 614 bits (1584), Expect = e-175, Method: Compositional matrix adjust. Identities = 293/431 (67%), Positives = 345/431 (80%), Gaps = 5/431 (1%) Query: 1 MIDIQLLRKDIDNVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+DIQLLR + VA RLA R + D A F+ALE RK +Q +TEELQ RNS+SKQIG Sbjct: 1 MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGA 60 Query: 61 LKGKG--EDASAVMAEVNGIGDELKASATRLDEVQQQMTLFLQAVPNLPHESVPVGNDEN 118 LKG+G E+A M +V I +L+ +A LD VQ+++ +L ++PNLPHE VP G DE Sbjct: 61 LKGQGKHEEAQVAMDQVAQIKTDLEQAAADLDAVQKELDAWLLSIPNLPHEDVPFGKDET 120 Query: 119 GNVELRKVGTPRQFDFEIKDHVDVGAPLGLDFDTATKLTGSRFAVLKGGIARLHRALAQF 178 NVE+RKVGTPR+FDFEIKDHVD+G PLGLDF+ KL+G+RF V++G IARLHRALAQF Sbjct: 121 ENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSGARFTVMRGQIARLHRALAQF 180 Query: 179 MLNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPT 238 ML+THT++HGYTE YTPYIV+ +L+GTGQLPKF DLF +GG E + YLIPT Sbjct: 181 MLDTHTLKHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDESKTTQ---YLIPT 237 Query: 239 AEVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVH 298 AEV LTN V I+ + LP+K TAHSPCFRSEAGSYG+DTRG+IRQHQFDKVEMVQIVH Sbjct: 238 AEVTLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVH 297 Query: 299 PEQSYAALEEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREIS 358 PE+SY LEEM+GHAE ILK L LPYRVITLCTGDMGFGA KTYD+EVW+PAQNTYREIS Sbjct: 298 PEKSYETLEEMVGHAENILKALELPYRVITLCTGDMGFGATKTYDLEVWVPAQNTYREIS 357 Query: 359 SVSNCEAFQARRMQARFRNAQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEV 418 S SNCE FQARRM+ARF++ GK L+HTLNGSGLAVGRTLVAVLEN+Q ADGS++IP Sbjct: 358 SCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVAVLENHQNADGSINIPAA 417 Query: 419 LQPYMGGVSKL 429 LQPYMGGV+KL Sbjct: 418 LQPYMGGVAKL 428 >PA2612 [J] COG0172 Seryl-tRNA synthetase Pae Pseudomonas aeruginosa Length = 426 Score = 569 bits (1467), Expect = e-162, Method: Compositional matrix adjust. Identities = 277/428 (64%), Positives = 338/428 (78%), Gaps = 8/428 (1%) Query: 1 MIDIQLLRKDIDNVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+D +L+R VAARLA R F LDVA ALE +RK +QTRTE+LQ +RN+ SK IG Sbjct: 1 MLDPKLVRTQPQEVAARLATRGFQLDVARIEALEEQRKSVQTRTEQLQAERNARSKAIGQ 60 Query: 61 LKGKGEDASAVMAEVNGIGDELKASATRLDEVQQQMTLFLQAVPNLPHESVPVGNDENGN 120 K +GED + ++A+V+ +G EL+ +LD +Q ++ L +PNLPHESVPVG DE+ N Sbjct: 61 AKQRGEDIAPLLADVDRMGSELEEGKRQLDAIQGELDAMLLGIPNLPHESVPVGADEDAN 120 Query: 121 VELRKVGTPRQFDFEIKDHVDVGAPLG-LDFDTATKLTGSRFAVLKGGIARLHRALAQFM 179 VE+R+ GTP+ FDFE+KDHV +G G LDF+TA KL+G+RFA+++G IARLHRALAQFM Sbjct: 121 VEVRRWGTPKTFDFEVKDHVALGERHGWLDFETAAKLSGARFALMRGPIARLHRALAQFM 180 Query: 180 LNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPTA 239 +N HT EHGY E YTPY+V A +L+GTGQLPKFE DLF K G++GEA+ LYLIPTA Sbjct: 181 INLHTAEHGYEEAYTPYLVQAPALQGTGQLPKFEEDLF---KIGRDGEAD---LYLIPTA 234 Query: 240 EVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVHP 299 EV LTN V +I+ LP+KF AH+PCFRSEAG+ GRDTRGMIRQHQFDKVEMVQIV P Sbjct: 235 EVSLTNIVSGQILDAKQLPLKFVAHTPCFRSEAGASGRDTRGMIRQHQFDKVEMVQIVDP 294 Query: 300 EQSYAALEEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREISS 359 SY ALE + +AE +L+ L LPYRV+ LCTGDMGFGA KTYD+EVW+P+Q+ YREISS Sbjct: 295 ATSYEALEGLTANAERVLQLLELPYRVLALCTGDMGFGATKTYDLEVWVPSQDKYREISS 354 Query: 360 VSNCEAFQARRMQARFRNAQ-GKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEV 418 SNC FQARRMQAR+RN + GKPEL+HTLNGSGLAVGRTLVAVLENYQQADGS+ +PEV Sbjct: 355 CSNCGDFQARRMQARYRNPETGKPELVHTLNGSGLAVGRTLVAVLENYQQADGSIRVPEV 414 Query: 419 LQPYMGGV 426 L+PYM G+ Sbjct: 415 LKPYMAGI 422 >STM0963 [J] COG0172 Seryl-tRNA synthetase Sty Salmonella typhimurium LT2 Length = 430 Score = 556 bits (1434), Expect = e-158, Method: Compositional matrix adjust. Identities = 274/428 (64%), Positives = 323/428 (75%), Gaps = 4/428 (0%) Query: 1 MIDIQLLRKDIDNVAARLAARKFVLDVAGFNALEAERKQIQTRTEELQGKRNSLSKQIGM 60 M+D LLR + D VA +LA R F LDV ALE RK +Q TE LQ +RNS SK IG Sbjct: 1 MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVNTENLQAERNSRSKSIGQ 60 Query: 61 LKGKGEDASAVMAEVNGIGDELKASATRLDEVQQQMTLFLQAVPNLPHESVPVGNDENGN 120 K +GED + EVN +G+EL A+ LD + ++ +PNLP + VPVG DEN N Sbjct: 61 AKARGEDIEPLRLEVNKLGEELDAAKAELDTLLAEIRDIALTIPNLPADEVPVGKDENDN 120 Query: 121 VELRKVGTPRQFDFEIKDHVDVG-APLGLDFDTATKLTGSRFAVLKGGIARLHRALAQFM 179 VE+ + GTPR+FDFEI+DHV +G GLDF A KLTGSRF V+KG IAR+HRAL+QFM Sbjct: 121 VEVSRWGTPREFDFEIRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFM 180 Query: 180 LNTHTMEHGYTECYTPYIVNADSLRGTGQLPKFEADLFAAKKGGQEGEAENAALYLIPTA 239 L+ HT +HGY+E Y PY+VN D+L GTGQLPKF DLF + +E ++ N AL IPTA Sbjct: 181 LDLHTEQHGYSENYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLEEEADSSNYAL--IPTA 238 Query: 240 EVPLTNFVRDEIVAGDALPMKFTAHSPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQIVHP 299 EVPLTN VRDEI+ D LP+K TAH+PCFRSEAGSYGRDTRG+IR HQFDKVEMVQIV P Sbjct: 239 EVPLTNLVRDEIIDEDQLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRP 298 Query: 300 EQSYAALEEMLGHAETILKKLGLPYRVITLCTGDMGFGAAKTYDIEVWLPAQNTYREISS 359 E S AALEEM GHAE +L+ LGLPYR I LCTGDMGFGA KTYD+EVW+PAQNTYREISS Sbjct: 299 EDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWVPAQNTYREISS 358 Query: 360 VSNCEAFQARRMQARFRN-AQGKPELLHTLNGSGLAVGRTLVAVLENYQQADGSVDIPEV 418 SN FQARRMQAR R+ + K L+HTLNGSGLAVGRTLVAV+ENYQQADG +++PEV Sbjct: 359 CSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEV 418 Query: 419 LQPYMGGV 426 L+PYM G+ Sbjct: 419 LRPYMNGL 426