BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1773.p (434 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMA1433 [L] COG2256 ATPase related to the helicase subunit of th... 614 e-175 NMB1258 [L] COG2256 ATPase related to the helicase subunit of th... 613 e-175 RSc2338 [L] COG2256 ATPase related to the helicase subunit of th... 601 e-171 PA2613 [L] COG2256 ATPase related to the helicase subunit of the... 516 e-146 PM0257 [L] COG2256 ATPase related to the helicase subunit of the... 473 e-133 >NMA1433 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase NmA Neisseria meningitidis Z2491 Length = 436 Score = 614 bits (1583), Expect = e-175, Method: Compositional matrix adjust. Identities = 311/436 (71%), Positives = 359/436 (82%), Gaps = 5/436 (1%) Query: 1 MADLFAQEPAAPLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGK 60 M DLFA+EP APLAE LRP TLD+V+GQ HL+GEGKPLR+A + GKPHSM+ WGPPGVGK Sbjct: 1 MTDLFAREPYAPLAERLRPHTLDDVVGQEHLIGEGKPLRVAVEGGKPHSMLLWGPPGVGK 60 Query: 61 TTLARLTATAFQCEFIALSAVFSGVKDIRAAMEQAEQNLSMGKHTILFVDEIHRFNKSQQ 120 TTLAR+ A +F +F+ +SAVFSGVKDIR A+++AE L G+ TILFVDE+HRFNK+QQ Sbjct: 61 TTLARILAQSFNAQFLPVSAVFSGVKDIREAIDKAEIALQQGRATILFVDEVHRFNKAQQ 120 Query: 121 DALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDDELKLLLKRAQEKALG 180 DA LP+ ESGL+TFIGATTENPSFEVN ALLSRAQVYVL+ L+ D+LK L+ A+ AL Sbjct: 121 DAFLPHVESGLLTFIGATTENPSFEVNPALLSRAQVYVLQPLSSDDLKKLI--AKVLALP 178 Query: 181 ELQ---FDAQATDTIIGYADGDARRFLNLLEQTETAARTTGTTLVTAEFLQNALTLNSRR 237 E Q + A ++ DGDARR LNLLEQ AA T +TAEFL ++L RR Sbjct: 179 EYQEFTIETDAQKLLVNTVDGDARRLLNLLEQLLRAADTRRLKNLTAEFLADSLGAQIRR 238 Query: 238 FDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGLAD 297 FDKGG++FY+QISALHKSVRGSHP+AALYW RMLDGG DPRYL+RRIVR+AWEDIGLAD Sbjct: 239 FDKGGESFYNQISALHKSVRGSHPNAALYWFCRMLDGGTDPRYLARRIVRIAWEDIGLAD 298 Query: 298 PRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKSRE 357 PRA+QIANDAA T+ERLGSPEGELAL QAV+YLA AAKSNAGY AYN R FVK++ S E Sbjct: 299 PRALQIANDAAATFERLGSPEGELALAQAVLYLAAAAKSNAGYKAYNQMRHFVKENASDE 358 Query: 358 VPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPEGIAEPGWYQPVPRGLEIKI 417 VPVHLRNAPTKLMKELGYG EYRYAHDEPNAYAAGE+Y+P+G+ EP +YQPVPRGLEIKI Sbjct: 359 VPVHLRNAPTKLMKELGYGREYRYAHDEPNAYAAGESYMPDGLDEPDFYQPVPRGLEIKI 418 Query: 418 GEKLATLRQWDEEVGK 433 GEKLA L+ DEEV K Sbjct: 419 GEKLAWLKSLDEEVLK 434 >NMB1258 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Nme Neisseria meningitidis MC58 Length = 436 Score = 613 bits (1580), Expect = e-175, Method: Compositional matrix adjust. Identities = 310/436 (71%), Positives = 358/436 (82%), Gaps = 5/436 (1%) Query: 1 MADLFAQEPAAPLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGK 60 M DLFA+EP APLAE LRP TLD+V+GQ HL+GEGKPLR+A + GKPHSM+ WGPPGVGK Sbjct: 1 MTDLFAREPDAPLAERLRPHTLDDVVGQEHLIGEGKPLRVAVEGGKPHSMLLWGPPGVGK 60 Query: 61 TTLARLTATAFQCEFIALSAVFSGVKDIRAAMEQAEQNLSMGKHTILFVDEIHRFNKSQQ 120 TTLAR+ A +F +F+ +SAVFSGVKDIR A+++AE L G+ TILFVDE+HRFNK+QQ Sbjct: 61 TTLARILAQSFNAQFLPVSAVFSGVKDIREAIDKAEIALQQGRATILFVDEVHRFNKAQQ 120 Query: 121 DALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDDELKLLLKRAQEKALG 180 DA LP+ ESGL+TFIGATTENPSFEVN ALLSRAQVYVL+ L+ D+LK L+ A+ AL Sbjct: 121 DAFLPHVESGLLTFIGATTENPSFEVNPALLSRAQVYVLQPLSSDDLKKLI--AKVLALP 178 Query: 181 ELQ---FDAQATDTIIGYADGDARRFLNLLEQTETAARTTGTTLVTAEFLQNALTLNSRR 237 E Q + A ++ ADGDARR LNLLEQ AA T +TAEFL ++L RR Sbjct: 179 EYQEFTIETDAQKLLVNTADGDARRLLNLLEQLLRAADTRRLKNLTAEFLADSLGAQIRR 238 Query: 238 FDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGLAD 297 FDKGG++FY+QISALHKSVRGSHP+AALYW RMLDGG DPRYL+RRIVR+AWEDIGLAD Sbjct: 239 FDKGGESFYNQISALHKSVRGSHPNAALYWFCRMLDGGTDPRYLARRIVRIAWEDIGLAD 298 Query: 298 PRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKSRE 357 PRA QIANDAA T+ERLGSPEGELAL QAV+YLA AAKSNAGY AYN R FVK++ S E Sbjct: 299 PRAFQIANDAAATFERLGSPEGELALAQAVLYLAAAAKSNAGYKAYNQMRHFVKENASDE 358 Query: 358 VPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPEGIAEPGWYQPVPRGLEIKI 417 VPVHLRNAPTKLMKELGYG EYRYAHDEPNAY+AGE+Y+P+G+ EP +YQPVPRGLEIKI Sbjct: 359 VPVHLRNAPTKLMKELGYGREYRYAHDEPNAYSAGESYMPDGLDEPDFYQPVPRGLEIKI 418 Query: 418 GEKLATLRQWDEEVGK 433 GEKL L+ DEEV K Sbjct: 419 GEKLEWLKSLDEEVLK 434 >RSc2338 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Rso Ralstonia solanacearum Length = 449 Score = 601 bits (1549), Expect = e-171, Method: Compositional matrix adjust. Identities = 311/435 (71%), Positives = 348/435 (80%), Gaps = 7/435 (1%) Query: 2 ADLFAQEPAA--PLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVG 59 A LF P A PLAE LRP ++DEVIGQ HLLG KPLR+AF SG+PHSMI WGPPGVG Sbjct: 3 ASLFPDAPPAHMPLAERLRPHSVDEVIGQQHLLGPSKPLRVAFASGEPHSMILWGPPGVG 62 Query: 60 KTTLARLTATAFQCEFIALSAVFSGVKDIRAAMEQAEQNLSMGKHTILFVDEIHRFNKSQ 119 KTTLARL A AF EFIALSAV SGVKDIR A+E+AEQ + G+ T++FVDE+HRFNKSQ Sbjct: 63 KTTLARLMADAFDAEFIALSAVLSGVKDIRDAVERAEQFRAHGRRTLVFVDEVHRFNKSQ 122 Query: 120 QDALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDDELKLLLKRAQEKAL 179 QDA LP+ ESGL TFIGATTENPSFEVN ALLSRA VYVLKSL+DDELK L +RA+++ L Sbjct: 123 QDAFLPHVESGLFTFIGATTENPSFEVNGALLSRAAVYVLKSLSDDELKQLAERARQE-L 181 Query: 180 GELQFDAQATDTIIGYADGDARRFLNLLEQTETAART-TGTTLVTA---EFLQNALTLNS 235 G L++ A D ++ ADGD R+ LN +E AAR G+ V A L +AL+ N Sbjct: 182 GGLEWAPAAVDAVVASADGDGRKLLNNIEIVTRAARAQAGSETVPAIDEALLASALSENL 241 Query: 236 RRFDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGL 295 RRFDKGGD FYDQISALHKSVRGS PDAALYW RMLDGGADPRYL+RRIVRMAWEDIGL Sbjct: 242 RRFDKGGDAFYDQISALHKSVRGSDPDAALYWFCRMLDGGADPRYLARRIVRMAWEDIGL 301 Query: 296 ADPRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKS 355 ADPRA +I DAA TYERLGSPEGELAL QA+IYLA+A KSNAGYNAYNAARAFV DKS Sbjct: 302 ADPRAARITLDAAETYERLGSPEGELALAQALIYLAIAPKSNAGYNAYNAARAFVGHDKS 361 Query: 356 REVPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPEGIAEPGWYQPVPRGLEI 415 R VPVHLRNAPT+LMKELGYGH YRYAHDEP AYAAGETY P+ ++ GWY P PRGLE Sbjct: 362 RAVPVHLRNAPTRLMKELGYGHAYRYAHDEPEAYAAGETYFPDDLSPQGWYVPTPRGLEG 421 Query: 416 KIGEKLATLRQWDEE 430 KIG+KL LR+ D + Sbjct: 422 KIGDKLRHLRELDAQ 436 >PA2613 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Pae Pseudomonas aeruginosa Length = 441 Score = 516 bits (1330), Expect = e-146, Method: Compositional matrix adjust. Identities = 267/432 (61%), Positives = 316/432 (73%), Gaps = 8/432 (1%) Query: 3 DLFAQEPAA-PLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGKT 61 DLF EP A PLA LRP LDE +GQ HLL GKPLR A + G HSMIFWGPPGVGKT Sbjct: 2 DLFRSEPVAQPLAARLRPANLDEYVGQEHLLARGKPLREALEQGALHSMIFWGPPGVGKT 61 Query: 62 TLARLTATAFQCEFIALSAVFSGVKDIRAAMEQAEQNLSM-GKHTILFVDEIHRFNKSQQ 120 TLARL A F +SAV SGVK+IR A+E A+Q+ + G+ TILFVDE+HRFNKSQQ Sbjct: 62 TLARLLAQVSDAHFETISAVLSGVKEIRQAVEVAKQHAAQYGRRTILFVDEVHRFNKSQQ 121 Query: 121 DALLPYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDDELKLLLKRA--QEKA 178 DA LPY E G + FIGATTENPSFE+N+ALLSRA+VYVLKSL + L+ L+ RA ++K Sbjct: 122 DAFLPYVEDGTLIFIGATTENPSFELNNALLSRARVYVLKSLDEAALRKLVGRALNEDKG 181 Query: 179 LGE--LQFDAQATDTIIGYADGDARRFLNLLEQTETAARTTGTTLVTAEFLQNALTLNSR 236 LG+ L+ ++ ++ ADGD RR LNLLE A ++ E LQN L R Sbjct: 182 LGKRKLRLPEESFQVLLAAADGDGRRLLNLLENAADLAEDGSE--ISPELLQNLLGDTRR 239 Query: 237 RFDKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGLA 296 RFDKGG+ FYDQISALHKSVRGS+PDAALYW RMLDGG DP Y++RR+VRMA E++G A Sbjct: 240 RFDKGGEAFYDQISALHKSVRGSNPDAALYWFARMLDGGCDPLYIARRVVRMASEEVGNA 299 Query: 297 DPRAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKSR 356 DPRA+ + A ERLGSPEGELA+ QA++YLA A KSNA Y+A+NAA V + SR Sbjct: 300 DPRALGLCLSAWDVQERLGSPEGELAVAQAIVYLACAPKSNAVYSAFNAAMRDVAESGSR 359 Query: 357 EVPVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPEGIAEPGWYQPVPRGLEIK 416 EVP+HLRNAPTKLMK LGYG EYRYAHDEP+AYAAGE Y PE + +YQPVPRGLE+K Sbjct: 360 EVPLHLRNAPTKLMKSLGYGEEYRYAHDEPDAYAAGEDYFPEDLEPRRYYQPVPRGLELK 419 Query: 417 IGEKLATLRQWD 428 I +KL L + D Sbjct: 420 IRDKLEHLAELD 431 >PM0257 [L] COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase Pmu Pasteurella multocida Length = 445 Score = 473 bits (1216), Expect = e-133, Method: Compositional matrix adjust. Identities = 241/436 (55%), Positives = 303/436 (69%), Gaps = 6/436 (1%) Query: 5 FAQEPAAPLAEALRPKTLDEVIGQSHLLGEGKPLRLAFQSGKPHSMIFWGPPGVGKTTLA 64 FAQ+ PLA +RP T + GQSHL+GEGKPLR A +G HSMI WGPPG GKTTLA Sbjct: 8 FAQQAFQPLAARMRPTTFAQYCGQSHLIGEGKPLRKALDAGHVHSMILWGPPGTGKTTLA 67 Query: 65 RLTATAFQCEFIALSAVFSGVKDIRAAMEQAEQNLSMGKHTILFVDEIHRFNKSQQDALL 124 + A + +SAV SG+K+IR A+E+A++N + TILFVDE+HRFNKSQQDA L Sbjct: 68 EIIAHQIHADVERISAVTSGIKEIREAIERAKENRLAERRTILFVDEVHRFNKSQQDAFL 127 Query: 125 PYAESGLVTFIGATTENPSFEVNSALLSRAQVYVLKSLTDDELKLLLKRA---QEKALGE 181 P+ E G + FIGATTENPSFE+N+ALLSRA+VY+LKSL+ E+ +LK+A +E+ LG+ Sbjct: 128 PHIEDGTIIFIGATTENPSFELNNALLSRAKVYILKSLSTQEITEVLKQALLDEERGLGK 187 Query: 182 LQF--DAQATDTIIGYADGDARRFLNLLE-QTETAARTTGTTLVTAEFLQNALTLNSRRF 238 ++F + + + Y +GDAR LN LE + A T +T L+N L RF Sbjct: 188 VRFVLEENVLECLAEYVNGDARLALNSLELMADMAEETEAGKALTLSLLKNVLGERQARF 247 Query: 239 DKGGDNFYDQISALHKSVRGSHPDAALYWLTRMLDGGADPRYLSRRIVRMAWEDIGLADP 298 DK GD FYD ISALHKSVRGS PDAALYW R+L G DP Y++RR++ +A ED+G ADP Sbjct: 248 DKQGDRFYDAISALHKSVRGSAPDAALYWYARILAAGGDPLYVARRLLAIASEDVGNADP 307 Query: 299 RAMQIANDAALTYERLGSPEGELALGQAVIYLAVAAKSNAGYNAYNAARAFVKQDKSREV 358 RAMQ+A A + R+G+ EGE A+ QA++YLAVA KSNA Y A+N A+ VK+ EV Sbjct: 308 RAMQVALAAWDCFTRVGAAEGERAIAQAIVYLAVAPKSNAVYRAFNQAKQHVKETPDYEV 367 Query: 359 PVHLRNAPTKLMKELGYGHEYRYAHDEPNAYAAGETYLPEGIAEPGWYQPVPRGLEIKIG 418 P HLRNAPT LMK LGYG YRYAHDE +AYAAGE Y PE + + +Y P RG+EIKI Sbjct: 368 PAHLRNAPTHLMKTLGYGEAYRYAHDEEHAYAAGENYFPEALKDTQYYFPTHRGMEIKIK 427 Query: 419 EKLATLRQWDEEVGKK 434 EKL LRQ D++ KK Sbjct: 428 EKLDWLRQQDQQSKKK 443