BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1762.p (506 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc02689 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme S... 852 0.0 BH0681 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bac... 825 0.0 mll6639 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Me... 822 0.0 DRA0348 [C] COG1012 NAD-dependent aldehyde dehydrogenases Dra De... 816 0.0 BMEI1747 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme B... 808 0.0 >SMc02689 [C] COG1012 NAD-dependent aldehyde dehydrogenases Sme Sinorhizobium meliloti Length = 502 Score = 852 bits (2200), Expect = 0.0, Method: Compositional matrix adjust. Identities = 402/496 (81%), Positives = 442/496 (89%) Query: 11 VRDPFKQRYDNFIGGKFVPPVKGEYFENISPVIGRAFCEVARSSAEDVELALDAAHAAKK 70 V +P+KQ+Y NFIGG++ PV G YF+N +P+ G CEVARS A D+E+ALDAAHAA++ Sbjct: 7 VENPYKQKYGNFIGGEWREPVAGRYFDNTTPITGGTLCEVARSDAADIEIALDAAHAARE 66 Query: 71 AWGKTSPTERANLLLKIADRMEANLELLATAETLDNGKPIRETMAADIPLAIDHFRYFAA 130 WG+TS TER+N+L+KIA RME NLELLA AET DNGKPIRETMAADIPLAIDHFRYFAA Sbjct: 67 KWGRTSTTERSNILMKIAARMEDNLELLARAETWDNGKPIRETMAADIPLAIDHFRYFAA 126 Query: 131 AVRTQEGSICPIDDDTYAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNCVVLKPA 190 +R QEGSI ID DT AYHFHEPLGVVGQIIPWNFPILMA WKLAPALAAGNCVVLKPA Sbjct: 127 CIRAQEGSIGEIDHDTVAYHFHEPLGVVGQIIPWNFPILMAAWKLAPALAAGNCVVLKPA 186 Query: 191 EQTPASIMVLVELIADLLPPGVLNIVQGFGVEAGKPLASNKRIAKIAFTGETTTGRLIMQ 250 EQTP SI+V ELI DLLPPGVLNIV GFG+EAGKPLA++ RIAKIAFTGETTTGRLIMQ Sbjct: 187 EQTPGSILVWAELIGDLLPPGVLNIVNGFGLEAGKPLATSPRIAKIAFTGETTTGRLIMQ 246 Query: 251 YASQNLIPVTLELGGKSPNIFFADVLDKDDAFFDKALEGFAMFALNQGEVCTCPSRVLVQ 310 YASQNLIPVTLELGGKSPNIFFADV +DD FFDKALEGFAMFALNQGEVCTCPSR LVQ Sbjct: 247 YASQNLIPVTLELGGKSPNIFFADVASEDDDFFDKALEGFAMFALNQGEVCTCPSRALVQ 306 Query: 311 ESIYERFIERALKRVAAIKQGNPLDKSTMIGAQASQEQLEKILSYIDIGKQEGAKVLAGG 370 ESIY+RF+ERA+KRV AI+QGNPLD++TMIGAQAS EQLEKIL+YI+IGK+EGA+VL GG Sbjct: 307 ESIYDRFMERAVKRVEAIRQGNPLDEATMIGAQASSEQLEKILAYIEIGKEEGAEVLTGG 366 Query: 371 GREELGGDLASGYYVKPTVFQGNNKMRIFQEEIFGPVVSVTTFKDEEEALAIANDTLYGL 430 GR L GDL+ GYYVKPTVF G+N+MRIFQEEIFGPVVSVTTFK E EAL IANDTLYGL Sbjct: 367 GRNVLEGDLSGGYYVKPTVFHGHNRMRIFQEEIFGPVVSVTTFKTEAEALEIANDTLYGL 426 Query: 431 GAGLWTRDGTRAFRMGREIQAGRVWTNCYHLYPAHAAFGGYKQSGIGRENHKMMLDHYQQ 490 GAG+W+RD R +R GR I+AGRVWTNCYH YPAHAAFGGYKQSGIGRE HKMMLDHYQQ Sbjct: 427 GAGVWSRDANRCYRFGRAIEAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLDHYQQ 486 Query: 491 TKNLLVSYSPKALGFF 506 TKN+LVSYSPKALGFF Sbjct: 487 TKNMLVSYSPKALGFF 502 >BH0681 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bha Bacillus halodurans Length = 506 Score = 825 bits (2132), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/492 (80%), Positives = 441/492 (89%) Query: 15 FKQRYDNFIGGKFVPPVKGEYFENISPVIGRAFCEVARSSAEDVELALDAAHAAKKAWGK 74 FK+RYDN++ G++ PPVKG+YFEN++PV G FCEVARS+AED++LALDAAHAAK+ WGK Sbjct: 15 FKKRYDNYVNGEWTPPVKGQYFENVTPVTGEVFCEVARSTAEDIDLALDAAHAAKEQWGK 74 Query: 75 TSPTERANLLLKIADRMEANLELLATAETLDNGKPIRETMAADIPLAIDHFRYFAAAVRT 134 TSP ERANLL KIADRME NLE LA AET +NGKP+RET+ ADIPLAIDHFRYFA A+R Sbjct: 75 TSPAERANLLNKIADRMEENLEKLAVAETWENGKPVRETLNADIPLAIDHFRYFAGAIRA 134 Query: 135 QEGSICPIDDDTYAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTP 194 QEG++ ID+DT AYHFHEPLGVVGQIIPWNFPILMA WKLAPALAAGNCV+LKPAEQTP Sbjct: 135 QEGTLSQIDNDTVAYHFHEPLGVVGQIIPWNFPILMATWKLAPALAAGNCVILKPAEQTP 194 Query: 195 ASIMVLVELIADLLPPGVLNIVQGFGVEAGKPLASNKRIAKIAFTGETTTGRLIMQYASQ 254 ASI VL+ELI DLLP GV+NIV GFGVEAGKPLAS+ R+AK+AFTGETTTGRLIMQYAS+ Sbjct: 195 ASIFVLLELIEDLLPKGVVNIVNGFGVEAGKPLASSSRVAKVAFTGETTTGRLIMQYASE 254 Query: 255 NLIPVTLELGGKSPNIFFADVLDKDDAFFDKALEGFAMFALNQGEVCTCPSRVLVQESIY 314 NLIPVTLELGGKSPNIFF DV+ KDDAF +KA+EGF +FALNQGEVCTCPSR L+QESIY Sbjct: 255 NLIPVTLELGGKSPNIFFDDVMAKDDAFLNKAIEGFVLFALNQGEVCTCPSRALIQESIY 314 Query: 315 ERFIERALKRVAAIKQGNPLDKSTMIGAQASQEQLEKILSYIDIGKQEGAKVLAGGGREE 374 + F+ERAL RV AIKQGNPLD +TMIGAQASQEQLEKILSY+ IGK+EGA+VLAGG R Sbjct: 315 DTFMERALARVQAIKQGNPLDPNTMIGAQASQEQLEKILSYLAIGKEEGAEVLAGGERNH 374 Query: 375 LGGDLASGYYVKPTVFQGNNKMRIFQEEIFGPVVSVTTFKDEEEALAIANDTLYGLGAGL 434 L G+LA+GYYV PTVF+G N MR+FQEEIFGPVVSVTTFKD EEALAIANDTLYGLGAG+ Sbjct: 375 LPGELANGYYVSPTVFKGTNDMRVFQEEIFGPVVSVTTFKDAEEALAIANDTLYGLGAGV 434 Query: 435 WTRDGTRAFRMGREIQAGRVWTNCYHLYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNL 494 WTRD +A+R GREIQAGRVWTNCYH YPAHAAFGGYK+SGIGRE H MML HYQQTKNL Sbjct: 435 WTRDMNKAYRFGREIQAGRVWTNCYHAYPAHAAFGGYKKSGIGRETHLMMLSHYQQTKNL 494 Query: 495 LVSYSPKALGFF 506 LVSYS ALGFF Sbjct: 495 LVSYSEDALGFF 506 >mll6639 [C] COG1012 NAD-dependent aldehyde dehydrogenases Mlo Mesorhizobium loti Length = 505 Score = 822 bits (2124), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/506 (79%), Positives = 445/506 (87%), Gaps = 1/506 (0%) Query: 1 MNLADISKLGVRDPFKQRYDNFIGGKFVPPVKGEYFENISPVIGRAFCEVARSSAEDVEL 60 MN + S+ V+ PF +RY NFIGGK+ P G YFEN SPV G+ CEVARS A+D+E Sbjct: 1 MNKVEFSR-PVKAPFDKRYGNFIGGKWTEPRSGRYFENHSPVNGQLLCEVARSDADDIEA 59 Query: 61 ALDAAHAAKKAWGKTSPTERANLLLKIADRMEANLELLATAETLDNGKPIRETMAADIPL 120 ALDAAHAAK AWG+TS ER+ +L +IADRME NL+LLA AET DNGKPIRET AD+PL Sbjct: 60 ALDAAHAAKDAWGRTSVAERSLILNRIADRMEENLDLLACAETWDNGKPIRETTVADLPL 119 Query: 121 AIDHFRYFAAAVRTQEGSICPIDDDTYAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALA 180 AIDHFRYFA+AVR QEGS+ IDDDT AYHFHEPLGVVGQIIPWNFP+LMA WKLAPALA Sbjct: 120 AIDHFRYFASAVRGQEGSLSQIDDDTVAYHFHEPLGVVGQIIPWNFPLLMACWKLAPALA 179 Query: 181 AGNCVVLKPAEQTPASIMVLVELIADLLPPGVLNIVQGFGVEAGKPLASNKRIAKIAFTG 240 AGNCVVLKPAEQTPA+I++ +LI DLLPPGVLNIV GFG+EAGKPLAS+ RIAKIAFTG Sbjct: 180 AGNCVVLKPAEQTPAAILLWADLIGDLLPPGVLNIVNGFGLEAGKPLASSPRIAKIAFTG 239 Query: 241 ETTTGRLIMQYASQNLIPVTLELGGKSPNIFFADVLDKDDAFFDKALEGFAMFALNQGEV 300 ETTTGRLIMQYASQNLIPVTLELGGKSPNIFF DV+ +DD FFDKA+EGF MFALNQGEV Sbjct: 240 ETTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVVAEDDDFFDKAIEGFVMFALNQGEV 299 Query: 301 CTCPSRVLVQESIYERFIERALKRVAAIKQGNPLDKSTMIGAQASQEQLEKILSYIDIGK 360 CTCPSR L+ ESIY+RF+ERALKRV AI QG+PLD +TMIGAQAS EQLEKILSYIDIG+ Sbjct: 300 CTCPSRALIHESIYDRFMERALKRVEAIVQGDPLDPATMIGAQASSEQLEKILSYIDIGR 359 Query: 361 QEGAKVLAGGGREELGGDLASGYYVKPTVFQGNNKMRIFQEEIFGPVVSVTTFKDEEEAL 420 QEGA+VL GG R L GDLA GYYVKPTVF+G+NKMRIFQEEIFGPVVSVTTFKD++EAL Sbjct: 360 QEGAEVLTGGARNVLPGDLAGGYYVKPTVFRGHNKMRIFQEEIFGPVVSVTTFKDDDEAL 419 Query: 421 AIANDTLYGLGAGLWTRDGTRAFRMGREIQAGRVWTNCYHLYPAHAAFGGYKQSGIGREN 480 +IANDTLYGLGAG+WTRDG RA+R GR IQAGRVWTNCYH YPAHAAFGGYKQSGIGRE Sbjct: 420 SIANDTLYGLGAGVWTRDGNRAYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRET 479 Query: 481 HKMMLDHYQQTKNLLVSYSPKALGFF 506 HKMMLDHYQQTKN+LVSYSPK LGFF Sbjct: 480 HKMMLDHYQQTKNMLVSYSPKKLGFF 505 >DRA0348 [C] COG1012 NAD-dependent aldehyde dehydrogenases Dra Deinococcus radiodurans Length = 515 Score = 816 bits (2109), Expect = 0.0, Method: Compositional matrix adjust. Identities = 385/492 (78%), Positives = 435/492 (88%), Gaps = 1/492 (0%) Query: 15 FKQRYDNFIGGKFVPPVKGEYFENISPVIGRAFCEVARSSAEDVELALDAAHAAKKAWGK 74 FK+RYDNFIGG++VPPVKG+YF+N SPV G+ F + ARS+AEDVELALDAAH A AWG+ Sbjct: 25 FKKRYDNFIGGQWVPPVKGQYFDNASPVDGKVFTQAARSTAEDVELALDAAHRAAPAWGR 84 Query: 75 TSPTERANLLLKIADRMEANLELLATAETLDNGKPIRETMAADIPLAIDHFRYFAAAVRT 134 TS TER+N+LLKIADRME NLE+LA AET DNGKP+RET+AAD+PLAIDHFRYFA +R Sbjct: 85 TSVTERSNILLKIADRMEQNLEMLAVAETWDNGKPVRETLAADLPLAIDHFRYFAGCIRA 144 Query: 135 QEGSICPIDDDTYAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTP 194 QEG + IDD T AYHFHEPLGVVGQIIPWNFP+LM VWKLAPALAAGN VVLKPAEQTP Sbjct: 145 QEGGLSQIDDSTVAYHFHEPLGVVGQIIPWNFPLLMGVWKLAPALAAGNAVVLKPAEQTP 204 Query: 195 ASIMVLVELIADLLPPGVLNIVQGFGVEAGKPLASNKRIAKIAFTGETTTGRLIMQYASQ 254 ASIMVL+ELIADLLP GV+N+V GFG+EAGKPLAS+ RIAKIAFTGET TGRLIM YA+ Sbjct: 205 ASIMVLMELIADLLPEGVVNVVNGFGLEAGKPLASSPRIAKIAFTGETNTGRLIMGYAAD 264 Query: 255 NLIPVTLELGGKSPNIFFADVLDKDDAFFDKALEGFAMFALNQGEVCTCPSRVLVQESIY 314 NLIPVTLELGGKSPNIFF DV+ +DDAF DKA+EG MFALNQGEVCTCPSR L+QESIY Sbjct: 265 NLIPVTLELGGKSPNIFFDDVMMEDDAFLDKAVEGMVMFALNQGEVCTCPSRALIQESIY 324 Query: 315 ERFIERALKRVAAIKQGNPLDKSTMIGAQASQEQLEKILSYIDIGKQEGAKVLAGGGREE 374 +RF+ERA++RV AI G+PLD TMIGAQAS EQL+KILSY+DIG+ EGA+VL GG R + Sbjct: 325 DRFMERAVQRVEAITMGHPLDPGTMIGAQASTEQLDKILSYLDIGRAEGAEVLTGGERGQ 384 Query: 375 LGGDLASGYYVKPTVFQGNNKMRIFQEEIFGPVVSVTTFKDEEEALAIANDTLYGLGAGL 434 G L G+YVKPT+F+G+NKMRIFQEEIFGPV++ TFKDE EAL +ANDTLYGLGAGL Sbjct: 385 REG-LEEGFYVKPTIFKGHNKMRIFQEEIFGPVLAAATFKDEAEALELANDTLYGLGAGL 443 Query: 435 WTRDGTRAFRMGREIQAGRVWTNCYHLYPAHAAFGGYKQSGIGRENHKMMLDHYQQTKNL 494 WTRD +RA+RMGR IQAGRVWTNCYH+YPAHAAFGGYKQSGIGRENH+MMLDHYQQTKNL Sbjct: 444 WTRDISRAYRMGRGIQAGRVWTNCYHVYPAHAAFGGYKQSGIGRENHRMMLDHYQQTKNL 503 Query: 495 LVSYSPKALGFF 506 LVSYSP +GFF Sbjct: 504 LVSYSPNKMGFF 515 >BMEI1747 [C] COG1012 NAD-dependent aldehyde dehydrogenases Bme Brucella melitensis Length = 505 Score = 808 bits (2087), Expect = 0.0, Method: Compositional matrix adjust. Identities = 396/506 (78%), Positives = 437/506 (86%), Gaps = 1/506 (0%) Query: 1 MNLADISKLGVRDPFKQRYDNFIGGKFVPPVKGEYFENISPVIGRAFCEVARSSAEDVEL 60 MN + S+ V+ F +RY NFIGGK+V P G YFEN SPV G+ CEVARS A DVE Sbjct: 1 MNKVEFSRT-VKPAFAKRYGNFIGGKWVEPRSGRYFENTSPVNGQVLCEVARSDAADVEA 59 Query: 61 ALDAAHAAKKAWGKTSPTERANLLLKIADRMEANLELLATAETLDNGKPIRETMAADIPL 120 ALDAAHAA++ WG+TS ERA +L +IADR+E NL LA AET DNGKPIRET AD+PL Sbjct: 60 ALDAAHAARELWGRTSVAERALILNRIADRIEENLPALAAAETWDNGKPIRETTNADLPL 119 Query: 121 AIDHFRYFAAAVRTQEGSICPIDDDTYAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALA 180 A+DHFRYFA +R QEG I ID DT AYHFHEPLGVVGQIIPWNFP+LMA WKLAPALA Sbjct: 120 AVDHFRYFAGVIRAQEGGISEIDHDTVAYHFHEPLGVVGQIIPWNFPLLMATWKLAPALA 179 Query: 181 AGNCVVLKPAEQTPASIMVLVELIADLLPPGVLNIVQGFGVEAGKPLASNKRIAKIAFTG 240 AGNCVVLKPAEQTPASI+VL+ELIAD+LPPGV+NIV GFG+EAGKPLAS+ RIAKIAFTG Sbjct: 180 AGNCVVLKPAEQTPASILVLMELIADILPPGVVNIVNGFGLEAGKPLASSPRIAKIAFTG 239 Query: 241 ETTTGRLIMQYASQNLIPVTLELGGKSPNIFFADVLDKDDAFFDKALEGFAMFALNQGEV 300 ETTTGRLIMQYASQNLIPVTLELGGKSPNIFF DV +DD F DKA+EGF MFALNQGEV Sbjct: 240 ETTTGRLIMQYASQNLIPVTLELGGKSPNIFFKDVAAEDDDFLDKAIEGFVMFALNQGEV 299 Query: 301 CTCPSRVLVQESIYERFIERALKRVAAIKQGNPLDKSTMIGAQASQEQLEKILSYIDIGK 360 CTCPSR L+QESIY+RF+E+ALKRV AI QG+PLD +TMIGAQAS EQLEKILSY+DIG+ Sbjct: 300 CTCPSRALIQESIYDRFMEKALKRVEAIVQGDPLDPATMIGAQASSEQLEKILSYLDIGR 359 Query: 361 QEGAKVLAGGGREELGGDLASGYYVKPTVFQGNNKMRIFQEEIFGPVVSVTTFKDEEEAL 420 QEGA+VLAG R L GDLA GYYVKPTVF+G+NKMRIFQEEIFGPVVSV TFKD+ EAL Sbjct: 360 QEGAEVLAGNERNMLPGDLAGGYYVKPTVFKGHNKMRIFQEEIFGPVVSVATFKDDAEAL 419 Query: 421 AIANDTLYGLGAGLWTRDGTRAFRMGREIQAGRVWTNCYHLYPAHAAFGGYKQSGIGREN 480 +IANDTLYGLGAG+WTRDGTRA+R GR I+AGRVWTNCYH YPAHAAFGGYKQSGIGREN Sbjct: 420 SIANDTLYGLGAGIWTRDGTRAYRFGRAIKAGRVWTNCYHAYPAHAAFGGYKQSGIGREN 479 Query: 481 HKMMLDHYQQTKNLLVSYSPKALGFF 506 H MLDHYQ TKN+LVSYSPK LGFF Sbjct: 480 HLKMLDHYQNTKNMLVSYSPKKLGFF 505