BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1719.p (532 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0663 [GEPR] COG0477 Permeases of the major facilitator superf... 665 0.0 DR0258 [GEPR] COG0477 Permeases of the major facilitator superfa... 230 7e-60 BS_yusP [GEPR] COG0477 Permeases of the major facilitator superf... 228 3e-59 DR1327 [GEPR] COG0477 Permeases of the major facilitator superfa... 211 4e-54 DRA0061 [GEPR] COG0477 Permeases of the major facilitator superf... 210 6e-54 >RSp0663 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 537 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/531 (65%), Positives = 429/531 (80%), Gaps = 3/531 (0%) Query: 1 MALHTDAAHSSGQVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAW 60 MALHT HS QVLPF+ESLLA LGICFV++LVALDQT+VGTALPT+VAELKGF+LYAW Sbjct: 8 MALHTALPHSHTQVLPFKESLLAMLGICFVVVLVALDQTVVGTALPTVVAELKGFDLYAW 67 Query: 61 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQG 120 VAT+YLLTSV+TVP+FGRLGD++GRKPFV+ASI+VF AS +CGMA SM FLV AR LQG Sbjct: 68 VATSYLLTSVVTVPVFGRLGDFYGRKPFVVASIVVFTLASVMCGMAGSMAFLVWARALQG 127 Query: 121 IGGGMLVGTCFASIADLFPDPRVRLRWQVILSASFGIATAVGPSLGGFLTEGLGWRWVFY 180 IGGGMLVGT +A IADLFPD RVRLRWQV+LSASFGIA A+GP+LGG++T+ LGWR VFY Sbjct: 128 IGGGMLVGTAYACIADLFPDARVRLRWQVLLSASFGIANAIGPTLGGWMTQALGWRSVFY 187 Query: 181 CNLPIGVISLFFVWRFVPHIRHMHHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGITG 240 N+P GV+ L+F WRF+PH+R HAG++R DW GALLI+ +LG+LQL VE LP+ G++ Sbjct: 188 VNVPFGVLGLWFAWRFLPHLRQSLHAGRIRPDWQGALLITAALGALQLSVEWLPRHGLSL 247 Query: 241 GMMALLAVSVAAFYALWKWEQRAAQAILPFEMLRDRALASLFLLSVLAGFAMFSLLMYAP 300 ++ L +S AAF LW WEQRA Q +LPFEM+RD ALA+LF+L+ L+GF+MF+LL YAP Sbjct: 248 PVLGWLVLSAAAFAGLWWWEQRAEQPLLPFEMVRDPALATLFVLAALSGFSMFALLFYAP 307 Query: 301 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGV 360 LLFQGGFG+SP++AGL+ITPLV CIT+ SI+NGR++TRIP P +M+ GFAL+A + G+ Sbjct: 308 LLFQGGFGMSPQQAGLVITPLVVCITLGSIINGRLVTRIPRPTVMLYAGFALLALALAGM 367 Query: 361 VLSDRNTGNGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 420 S R T L +ML G GLG VLPNLTVFAQQ+A R HLGIATALLQSLRM+GGM+ Sbjct: 368 AASSRATPQLALTLLMLLAGLGLGFVLPNLTVFAQQSAGRAHLGIATALLQSLRMVGGMI 427 Query: 421 GTAVTGTLVSQMYGAGVQKALESDHAAQWLKEFSDPEVLVNHDIQSVLLARLMQAGHDGS 480 GTA+ GTLVS+ Y AGV AL +D A QWL+ +DPE+L++H+ Q+ LLA++ AGHDG+ Sbjct: 428 GTALVGTLVSERYAAGVGDALRADGATQWLRRLADPEILIDHEAQTALLAQMQSAGHDGA 487 Query: 481 ALLEAAREALVGAIHMGIAIAIVAALVGLWMVGRVPPIRFDQDQKVDPVMS 531 ALL AAR LV AIH+G+ +A V A+VGLW V RVPP+ V+PV + Sbjct: 488 ALLGAARHVLVSAIHLGLIVAAVVAVVGLWRVRRVPPVAL---YHVEPVQT 535 >DR0258 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 544 Score = 230 bits (586), Expect = 7e-60, Method: Compositional matrix adjust. Identities = 182/520 (35%), Positives = 275/520 (52%), Gaps = 36/520 (6%) Query: 13 QVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVATAYLLTSVIT 72 L RE LLA GI V+ L +L+ T+VG+A+P ++++L GF LYAW TAY LT+ +T Sbjct: 13 NTLSEREKLLAFAGILTVLFLSSLNMTVVGSAMPRVISDLGGFHLYAWAFTAYSLTTTVT 72 Query: 73 VPIFGRLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFA 132 +PI G L D +GR+P ++ I+VF S G SM L+ R +QGIGGG L+ F Sbjct: 73 IPIVGTLSDRYGRRPLILLGIVVFALGSMGLGFVQSMEQLIALRAIQGIGGGTLMAMSFT 132 Query: 133 SIADLFPDPRVRLRWQVILSASFGIATAVGPSLGGFLTEGLGWRWVFYCNLPIGVISLFF 192 +IADLF P R R+Q A +GI++ VGP +GGFLT+ GWR VF+ NLP +++LFF Sbjct: 133 AIADLF-TPIERGRYQGYTGAVWGISSVVGPLVGGFLTDHFGWRSVFFLNLPFALLALFF 191 Query: 193 VWRFVPHIRHMHHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGITGGMMA-------- 244 +WRF + K D GA L++ ++ +L L V GG A Sbjct: 192 IWRFFRLPAPTPGSVKGGFDALGATLLAGAVTTLTLAVSW------GGGTYAWDSPRILG 245 Query: 245 --LLAVSVAAFYALWKWEQRAAQAILPFEMLRDRALASLFLLSVLAGF----AMFSLLMY 298 +++ A+YA R +AIL +LRDR + LL+ LAGF M++ ++Y Sbjct: 246 LLGATLALGAWYA--AHSARQERAILDLGLLRDRGI----LLASLAGFLVSAGMYAAILY 299 Query: 299 APLLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCL 358 PL QG G S +GL + PL+ + + S ++G++++R ++ +G AL+A+ L Sbjct: 300 LPLYMQGVRGSSASGSGLALAPLMGGMILTSTLSGQLVSRTGRYKRLI-VGGALVASLAL 358 Query: 359 GVVLSDRNTGNGFL-LAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIG 417 + + + +L + +M+ G GLG V LT+ Q AA R+ LG AT Q R IG Sbjct: 359 VLSSTLSLSTPLWLAVTMMILLGLGLGPVNSQLTLAVQNAAPRQKLGSATGGNQFFRQIG 418 Query: 418 GMLGTAVTGTLVSQMYGAGVQKALES---DHAAQWLKEFSDPEVLVNHDIQSVLLARLMQ 474 G L ++ G LV+ + L + A ++P +L + +L L + Sbjct: 419 GTLAVSLFGALVNAHLSHDLSAKLPAAVRRLPAPMQDAIANPNLLTSERATHLLGWALKK 478 Query: 475 AGHDG--SALLEAAREALVGAIHMGIAIAIVAALVGLWMV 512 GH + +++A R +VGAI + A LVGL V Sbjct: 479 MGHHEMLAPIMQALRGVMVGAIDQ--VFLVSAGLVGLAFV 516 >BS_yusP [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 541 Score = 228 bits (580), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 148/434 (34%), Positives = 240/434 (55%), Gaps = 38/434 (8%) Query: 18 RESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVATAYLLTSVITVPIFG 77 + +LL T G+ + ALD TIVGTA+P IV +L G + W+ TAYLLTS VPI G Sbjct: 11 KRTLLIT-GLIIAMFFSALDGTIVGTAMPKIVGDLGGLSMMTWLTTAYLLTSTTIVPIAG 69 Query: 78 RLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFASIADL 137 +L D GR+ ++ +I+F+ ASALCGMAN+M L++ RGLQGIGGG+++ I DL Sbjct: 70 KLADLLGRRIVYVSGLIIFMAASALCGMANNMTELIIFRGLQGIGGGIMMPMAMIVIGDL 129 Query: 138 FPDPRVRLRWQVILSASFGIATAVGPSLGGFLTEGLGWRWVFYCNLPIGVISLFFVWRFV 197 F + R ++Q + A +G+A+ +GP +GG++ + L W+WVFY NLP+G+I++ F+ R Sbjct: 130 FTGKQ-RAKFQGVFGAIYGLASVIGPQIGGWIVDSLNWKWVFYINLPVGIIAVIFIAR-- 186 Query: 198 PHIRHMHHAGKMRLDWPG---------ALLISLSLG-------SLQLLVELLPKRGITGG 241 ++ G + D G +LL++LS G S Q+L G Sbjct: 187 -GLQGRQQTGPINFDIAGIFTMIVGVVSLLLALSFGGKDYAWDSWQIL-----------G 234 Query: 242 MMALLAVSVAAFYALWKWEQRAAQAILPFEMLRDRALASLFLLSVLAGFAMFSLLMYAPL 301 + AL + + +F + E +A + ILP + ++R L L+ MF + + P Sbjct: 235 LFALALIGIVSFIIV---ESKAKEPILPMYLFKNRTFTFLNLIGFFMSIGMFGAITFVPF 291 Query: 302 LFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIP-NPNLMMNLGFALIAASCLGV 360 QG G+S E+G ++TP++ + + SI+ G+++ +I P ++ G ++A L + Sbjct: 292 FMQGIVGVSASESGTIMTPMMISMIITSIIGGQLVYKIGIKPQIIT--GMLVMAGGFLLL 349 Query: 361 VLSDRNTGNGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 420 D +T + M G G+GLV+P LT+ Q++ ++E LG+ T+ Q R IGG Sbjct: 350 TTLDLDTSKLVATSFMAIIGLGMGLVMPILTLALQESFSKEELGVVTSSSQFFRSIGGTF 409 Query: 421 GTAVTGTLVSQMYG 434 G + G +++ G Sbjct: 410 GITMLGAVMNARSG 423 >DR1327 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 477 Score = 211 bits (537), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 153/420 (36%), Positives = 225/420 (53%), Gaps = 30/420 (7%) Query: 18 RESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVATAYLLTSVITVPIFG 77 R LLAT+G+ + L AL+ ++V TA+P+++ +L G LYA YLLTS + P++G Sbjct: 14 RARLLATVGLIVGVFLNALESSVVATAMPSVINDLHGQSLYALPFAMYLLTSTVGSPLWG 73 Query: 78 RLGDYFGRKPFVIASIIVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFASIADL 137 R D GRK + ++F+ SALCG A SM +L+ AR LQG+G G L+ + +L Sbjct: 74 RASDLVGRKRLYLVGAVLFLVGSALCGAAQSMGWLIGARALQGLGAGALLTLSMTIVGEL 133 Query: 138 FPDPRVRLRWQVILSASFGIATAVGPSLGGFLTEGLGWRWVFYCNLPIGVISLFFVWRFV 197 + + R R Q +SA +GI+ GP LGG+LTE L WRW FY +LP G+++LF V RF Sbjct: 134 Y-SLQERSRVQAFISAVWGISGLAGPLLGGWLTETLSWRWTFYVSLPFGLLALFMVSRF- 191 Query: 198 PHIRHMHHAGKMR---LDWPGALLISLSLGSLQLLVELLPKRGITGGMMALLAVSVAAFY 254 +H G+ R LDW GA L +L G L G+ + +L+ + VA Sbjct: 192 -----LHETGERRAAQLDWAGAALFTLGSG--------LTIWGLEMKLWSLVGLGVATLV 238 Query: 255 ALWKWEQRAAQAILPFEMLRDRALASLFLLSVLAGFAMFSLLMYAPLLFQGGFGLSPREA 314 E R +LP LR+R A F + L G A F ++ Y PL QG G A Sbjct: 239 GAVLLELRHPAPLLPMRALRERTPAVAFAGNFLGGAAYFGVIAYLPLYAQGVSGKGATAA 298 Query: 315 GLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGVVLSDRN-----TGN 369 G ++TP++ T+ SI++ ++I IP L +GFAL+ L + + + + Sbjct: 299 GAILTPMLVGWTLTSILSAQLIRFIPLARL-SQIGFALLTLMFLALTFTVHSPLWVTSAL 357 Query: 370 GFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGMLGTAVTGTLV 429 GF A G G+G + +L + AQQAA+R LG T+ + R +GG LGTA+ L+ Sbjct: 358 GF------AVGMGMGFSMLSLLLAAQQAASRGELGAVTSGVMFARQMGGALGTALMALLI 411 >DRA0061 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 643 Score = 210 bits (535), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 159/444 (35%), Positives = 234/444 (52%), Gaps = 31/444 (6%) Query: 6 DAAH--SSGQVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFELYAWVAT 63 D AH + ++L R G+ + L ALDQTIV ALP IV+EL G LY+WV T Sbjct: 12 DPAHYINYAELLDLRTKKFIVFGVLLALFLSALDQTIVSAALPRIVSELNGLNLYSWVTT 71 Query: 64 AYLLTSVITVPIFGRLGDYFGRKPFVIASIIVFVGASALCGMA----------NSMLFLV 113 AYLL+S VPI+G+L D +GRKP ++ I+VF+ SALCG++ + M+ LV Sbjct: 72 AYLLSSAALVPIYGKLSDLYGRKPVLVFGIVVFLIGSALCGLSGEPFLGNLFGSPMMQLV 131 Query: 114 LARGLQGIGGGMLVGTCFASIADLFPDPRVRLRWQVILSASFGIATAVGPSLGGFLTEGL 173 + RGLQGIG L FA +ADLF +PR R ++Q + A FG+++ VGP LGGFLT+ L Sbjct: 132 VFRGLQGIGAAALATVAFAIVADLF-EPRERAKYQGLFGAVFGLSSVVGPLLGGFLTDQL 190 Query: 174 GWRWVFYCNLPIGVISLFFVWRFVPHIRHMHHAGKMR--LDWPGALLISLSLGSLQLLVE 231 WRWVFY N+PIG+++L ++ +P + A +R +D+ GA+LI + ++ LL+ Sbjct: 191 SWRWVFYVNVPIGLVALAVIFARMPRL-----ASGLRGSVDYLGAVLIVIF--TVPLLLA 243 Query: 232 LLPKRGITGG-----MMALLAVSVAAFYALWKWEQRAAQAILPFEMLRDRALASLFLLSV 286 L T G M+ L S+AA A WE+R I+P + D +A Sbjct: 244 LTWGADGTAGWTDAKMLGLFGTSLAALLAFIFWERRHESPIVPLTLFADPTIAWTMTSRF 303 Query: 287 LAGFAMFSLLMYAPLLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMM 346 L G +++ L G S AGL PL + + +G + R + ++ Sbjct: 304 LLGAGFLGAVLFLTLYLVNVAGFSATGAGLATLPLTLGFVIGAQGSGLLAARSGHYKSLL 363 Query: 347 NLGF--ALIAASCLGVVLSDRNTGNGFLLAVMLAGGFGLGLVLPNLTVFAQQAAAREHLG 404 + A++A L V D T G L A M G GLG + T+ AQ A A +G Sbjct: 364 VGAYVVAVLAFWWLSTVQVD--TPYGLLAARMFLVGLGLGPSVSLFTLAAQNAVAPYQIG 421 Query: 405 IATALLQSLRMIGGMLGTAVTGTL 428 + T++ + +GG +G A+ G + Sbjct: 422 VVTSVGTFFQQLGGTIGIALFGAI 445