BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1706.p (539 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0867 [E] COG0405 Gamma-glutamyltransferase Bha Bacillus halodu... 674 0.0 PA0164 [E] COG0405 Gamma-glutamyltransferase Pae Pseudomonas aer... 626 e-179 DR1524 [E] COG0405 Gamma-glutamyltransferase Dra Deinococcus rad... 537 e-152 Rv0773c [E] COG0405 Gamma-glutamyltransferase Mtu Mycobacterium ... 459 e-128 MT0797 [E] COG0405 Gamma-glutamyltransferase MtC Mycobacterium t... 459 e-128 >BH0867 [E] COG0405 Gamma-glutamyltransferase Bha Bacillus halodurans Length = 539 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/535 (61%), Positives = 409/535 (76%), Gaps = 2/535 (0%) Query: 7 FSSNHYPYLSRRSAVYARRGMVATSQPLAAQAGLEVLQRGGNAIDAAIAAAAALTVVEPT 66 F YPY SRR+ VYA+ GMVATSQPLAAQAGL++L+ GGNAIDAAIA A ALTV+EPT Sbjct: 5 FDPQSYPYPSRRNVVYAKNGMVATSQPLAAQAGLDILKAGGNAIDAAIATATALTVLEPT 64 Query: 67 ANGIGGDAFALVWHGGKLHGLNASGPAPQSISADKLTSAGL-KEMPKYGALPVTVPGTPS 125 +NGIG DAFALVW GKLHGLN SG AP S++ + + + G +E+P YG +PVTVPG P Sbjct: 65 SNGIGSDAFALVWTKGKLHGLNGSGRAPMSLTMEAVKAKGYEQELPPYGVIPVTVPGAPG 124 Query: 126 AWAAMAKRFGKLTLSDSMAGAITLAREGFPVSPMVAHAWQVAQQNFKREFKETHFQPWFD 185 AWA +AK +G L L+ S+A AI A EG+PV+P +A W+ A FK E+ + +QPWFD Sbjct: 125 AWAELAKMYGNLPLAASLAPAIRYAEEGYPVTPTLAKYWKAAYDRFKTEWTDDVYQPWFD 184 Query: 186 TFCIDGQAPQAGQLWRSAGHAATLQAIAEDGAESFYRGALAEQIAAFLQHAGGYLQAADL 245 TF G+AP+ G++WRS GHA TL++IAE ESFYRG LA+QI AF GGYL DL Sbjct: 185 TFAPKGRAPRVGEVWRSQGHADTLRSIAESNGESFYRGELADQIHAFFDKHGGYLTKEDL 244 Query: 246 AAFQAQWVDPIGVNYRGYEVWEIPPNGHGMVALMALNLLKAYDFTERDTLATYHRQIEAI 305 A ++ +WV+PI ++YRGY VWEIPPNG G+VAL ALN++K ++F +DT+ TYH+QIEA+ Sbjct: 245 ACYRPEWVEPISIDYRGYRVWEIPPNGQGLVALEALNIVKGFEFYHKDTVDTYHKQIEAM 304 Query: 306 KLAYADGLAHIADPAHMKVTVQQLLSDAYADERRQLIGPRATLPVAGDPSRGGTVYLCTA 365 KLA+ DG+ ++ +P+ M V+V+QLLSD YA ERR+ IG +A P G P RGGTVYL TA Sbjct: 305 KLAFVDGMKYVTEPSDMSVSVEQLLSDEYATERRKEIGEQALTPEPGTPPRGGTVYLATA 364 Query: 366 DAEGNMVSFIQSNYMGFGSGLVVPGTGIALHNRGNNFTLEAGHSNVLAGGKRPYHTIIPG 425 D +GNMVSFIQSNYMGFGSG+VVPGTGIA+ NRG+NF+L+ H N L GKR YHTIIPG Sbjct: 365 DGDGNMVSFIQSNYMGFGSGVVVPGTGIAMQNRGHNFSLDPNHDNALKPGKRTYHTIIPG 424 Query: 426 FMTRNGQAVGPFGVMGGFMQPQGHVQMVMNTVDFGLNPQAALDAPRWEWEKGNKVSIEHT 485 F+T+N Q +GPFGVMGGFMQPQGH+Q++MNT+DFGLNPQAALDAPRW+W G +V +E T Sbjct: 425 FLTKNDQPIGPFGVMGGFMQPQGHMQVMMNTIDFGLNPQAALDAPRWQWTNGKQVQVEPT 484 Query: 486 TAEHLFRGLGGLGHEVSWSGNQLGFGRGQIIWRN-DEGVLCGGTEPRTDGCVAAW 539 + + L GH++ ++ FGRGQIIWR+ GVL GGTEPRTDG VAAW Sbjct: 485 FPVDIAQALVRRGHKIQVVLDEGAFGRGQIIWRDPTTGVLAGGTEPRTDGQVAAW 539 >PA0164 [E] COG0405 Gamma-glutamyltransferase Pae Pseudomonas aeruginosa Length = 538 Score = 626 bits (1614), Expect = e-179, Method: Compositional matrix adjust. Identities = 316/536 (58%), Positives = 392/536 (73%), Gaps = 2/536 (0%) Query: 6 DFSSNHYPYLSRRSAVYARRGMVATSQPLAAQAGLEVLQRGGNAIDAAIAAAAALTVVEP 65 DFS++ PY S+RS V+ARRGMVATSQP AAQ GLE+L+RGGNAIDAAIA AAALTVVEP Sbjct: 3 DFSAHALPYASQRSPVHARRGMVATSQPQAAQVGLEILRRGGNAIDAAIATAAALTVVEP 62 Query: 66 TANGIGGDAFALVWHGGKLHGLNASGPAPQSISADKLTSAGLKEMPKYGALPVTVPGTPS 125 T GIGGDAFALVW G+LHGL+ASG AP + +++ +AG + MP YG PVTVPG P+ Sbjct: 63 TGCGIGGDAFALVWTRGRLHGLDASGRAPGLLDRERVRAAGHERMPLYGWTPVTVPGCPA 122 Query: 126 AWAAMAKRFGKLTLSDSMAGAITLAREGFPVSPMVAHAWQVAQQNFKREF-KETHFQPWF 184 AW +++RFGKL + AI LAR+GFPVSP++A WQ F+ + + WF Sbjct: 123 AWGELSRRFGKLPFEQLLRPAIELARDGFPVSPVIARLWQSGLDKFRAALPQRPELRAWF 182 Query: 185 DTFCIDGQAPQAGQLWRSAGHAATLQAIAEDGAESFYRGALAEQIAAFLQHAGGYLQAAD 244 D F IDG+AP+AG+++R G A TL +A ESFYRG LA I + +GGYL+A D Sbjct: 183 DEFLIDGRAPRAGEVFRQPGQADTLDELARSQCESFYRGELARAIVGHAECSGGYLRAED 242 Query: 245 LAAFQAQWVDPIGVNYRGYEVWEIPPNGHGMVALMALNLLKAYDFTERDTLATYHRQIEA 304 LA +QA+WV+PI +NYRGY+VWEIPP+G G++ALM LN+LK ++F ERD T+HRQ+EA Sbjct: 243 LAGYQAKWVEPISLNYRGYDVWEIPPSGQGLIALMTLNILKGFEFGERDCARTWHRQLEA 302 Query: 305 IKLAYADGLAHIADPAHMKVTVQQLLSDAYADERRQLIGPRATLPVAGDPSRGGTVYLCT 364 +KLAY DGL +I+ P M+V+V++LL + YA RR LIG RA P G P GGTVYL Sbjct: 303 MKLAYVDGLHYISQPQSMRVSVEELLHEDYAASRRALIGERALDPSPGQPRPGGTVYLAC 362 Query: 365 ADAEGNMVSFIQSNYMGFGSGLVVPGTGIALHNRGNNFTLEAGHSNVLAGGKRPYHTIIP 424 D EGN+VSFIQSNY GFGSG+VVPGTGIAL NRG F+L+ H N L GK+ +HTIIP Sbjct: 363 GDEEGNLVSFIQSNYHGFGSGVVVPGTGIALQNRGAEFSLDPDHVNCLEPGKQTFHTIIP 422 Query: 425 GFMTRNGQAVGPFGVMGGFMQPQGHVQMVMNTVDFGLNPQAALDAPRWEWEKGNKVSIEH 484 GF++++G +GPFGVMG +MQPQGHVQMVMN VDFGLNPQAALDAPRW+W G +V IEH Sbjct: 423 GFLSKDGVPLGPFGVMGAYMQPQGHVQMVMNLVDFGLNPQAALDAPRWQWLGGLRVGIEH 482 Query: 485 TTAEHLFRGLGGLGHEVSWSGNQLGFGRGQIIWRND-EGVLCGGTEPRTDGCVAAW 539 L L GH+V + + +GRGQI+ R+ GVLCGGTEPRTD +A W Sbjct: 483 AAPRALAAELAQRGHQVEIAYDSTSYGRGQIVLRDPASGVLCGGTEPRTDSQIAVW 538 >DR1524 [E] COG0405 Gamma-glutamyltransferase Dra Deinococcus radiodurans Length = 535 Score = 537 bits (1384), Expect = e-152, Method: Compositional matrix adjust. Identities = 303/538 (56%), Positives = 371/538 (68%), Gaps = 9/538 (1%) Query: 5 PDFSSNHYPYLSRRSAVYARRGMVATSQPLAAQAGLEVLQRGGNAIDAAIAAAAALTVVE 64 P + YP + R YARRGMVATSQPLAAQAGL +LQ GGNA+DAA+A AAALTVVE Sbjct: 4 PMTHNPEYPVVRR--PAYARRGMVATSQPLAAQAGLSILQAGGNAVDAAVATAAALTVVE 61 Query: 65 PTANGIGGDAFALVWHGGKLHGLNASGPAPQSISADKLTSAGLKEMPKYGALPVTVPGTP 124 PT+NG+GGDAFALVW GG+LHGLNASG AP ++S + L EMPKYG PVTVPG Sbjct: 62 PTSNGLGGDAFALVWAGGELHGLNASGAAPAALSLEALPGG---EMPKYGWTPVTVPGAV 118 Query: 125 SAWAAMAKRFGKLTLSDSMAGAITLAREGFPVSPMVAHAWQVAQQNFKREFKETHFQPWF 184 W + RFG+L + +A AI AREG+P+SP++A W A +++ F+ WF Sbjct: 119 RGWTDLHGRFGRLDFAQVLAPAIRYAREGYPLSPVLAANWARAIRSYW-ALNLPIFEDWF 177 Query: 185 DTFCIDGQAPQAGQLWRSAGHAATLQAIAEDGAESFYRGALAEQIAAFLQHAGGYLQAAD 244 TF DG P+ G LWRS GHA TL+ IA+ G +FY G LA QI A Q GG L+ +D Sbjct: 178 RTFAPDGFTPRPGALWRSEGHARTLELIAQTGGAAFYEGELAGQIDAHAQATGGLLRGSD 237 Query: 245 LAAFQAQWVDPIGVNYRGYEVWEIPPNGHGMVALMALNLLKAYDFTE-RDTLATYHRQIE 303 LAA +++WV PI ++ G+ V+EIPPNG G+ AL+ALN+L A E RD A H QIE Sbjct: 238 LAAHRSEWVKPIHTDWLGHRVYEIPPNGQGIAALVALNVLGAERLPELRDDPAGLHLQIE 297 Query: 304 AIKLAYADGLAHIADPAHMKVTVQQLLSDAYADERRQLIGPRATLPVAGDPSRGGTVYLC 363 A+K + D +++ADP H+ V V+ LLS A A+ R L+G +A P PS GGTVYL Sbjct: 298 AMKRGFHDAHSYVADPRHVPVDVEGLLSAANAERHRALLGEQAHDPATHAPSTGGTVYLA 357 Query: 364 TADAEGNMVSFIQSNYMGFGSGLVVPGTGIALHNRGNNFTLEAGHSNVLAGGKRPYHTII 423 AD EG MVS IQSNYMGFGSG+VVPGTGIALHNRG+NF + H N LA GKRPYHTII Sbjct: 358 AADDEGGMVSMIQSNYMGFGSGVVVPGTGIALHNRGHNFHTDPAHPNALAPGKRPYHTII 417 Query: 424 PGFMTR-NGQAVGPFGVMGGFMQPQGHVQMVMNTVDFGLNPQAALDAPRWEWEKGNKVSI 482 PGF+ R +G VGPFGVMGGFMQPQG +Q+V+NTV +G+NPQ ALDAPRW+W +G V + Sbjct: 418 PGFLGRADGTPVGPFGVMGGFMQPQGQLQVVVNTVRYGMNPQQALDAPRWQWLQGRTVEV 477 Query: 483 EHTTAEHLFRGLGGLGHEVSWSGNQLGFGRGQIIWRN-DEGVLCGGTEPRTDGCVAAW 539 E + L R L GH+V + FGRGQ+I R+ D GVL GGTE RTDG +A W Sbjct: 478 EPALGDQLARALVARGHDVRVQLDPGSFGRGQMIRRDPDTGVLEGGTESRTDGHIALW 535 >Rv0773c [E] COG0405 Gamma-glutamyltransferase Mtu Mycobacterium tuberculosis H37Rv Length = 512 Score = 459 bits (1180), Expect = e-128, Method: Compositional matrix adjust. Identities = 255/515 (49%), Positives = 322/515 (62%), Gaps = 14/515 (2%) Query: 27 MVATSQPLAAQAGLEVLQRGGNAIDAAIAAAAALTVVEPTANGIGGDAFALVWHGGKLHG 86 +V TSQPLAAQAGL +L GGNA+DAA+A A LTVVEP +NGIG DAF++VW G KLHG Sbjct: 8 VVCTSQPLAAQAGLRMLADGGNAVDAAVATAITLTVVEPVSNGIGSDAFSIVWDGQKLHG 67 Query: 87 LNASGPAPQSISADKLTSAGLKEMPKYGALPVTVPGTPSAWAAMAKRFGKLTLSDSMAGA 146 LNASG +P + + + G +P G VTVPG SAW + RFG+L A Sbjct: 68 LNASGRSPSAWTPEYF---GGNAVPVLGWNSVTVPGAVSAWVELHARFGRLPFETLFEPA 124 Query: 147 ITLAREGFPVSPMVAHAWQVAQQNFKREFKETHFQPWF-DTFCIDGQAPQAGQLWRSAGH 205 I+ R GF VSP VA W F QP F D F G+AP+ G+L+ H Sbjct: 125 ISYGRNGFLVSPTVAAQWAAQVPLFAS-------QPGFADAFMPGGRAPKPGELFTFPDH 177 Query: 206 AATLQAIAEDGAESFYRGALAEQIAAFLQHAGGYLQAADLAAFQAQWVDPIGVNYRGYEV 265 AATL+ IA E FYRG LA ++ A GG ++A DLAA + WVD I YRGY + Sbjct: 178 AATLEKIAATNGEEFYRGELAAKLEAHSAANGGVMRADDLAAHRVDWVDTITGTYRGYTI 237 Query: 266 WEIPPNGHGMVALMALNLLKAYDFTE--RDTLATYHRQIEAIKLAYADGLAHIADPAHMK 323 +IPPNG G+VAL+AL +L+ +D + D+ + H QIEA+KLA+AD A +AD +M Sbjct: 238 HQIPPNGQGIVALIALGILEHFDMSSWSVDSAESVHVQIEALKLAFADAQACVADIDYMP 297 Query: 324 VTVQQLLSDAYADERRQLIGPRATLPVAGDPSRGGTVYLCTADAEGNMVSFIQSNYMGFG 383 V ++LL Y +R LI P+ +P A RGGTVYL ADA G MVS IQSNY+GFG Sbjct: 298 VHPKRLLDKEYLRQRATLIDPKRAMPAATGIPRGGTVYLAAADAAGMMVSMIQSNYLGFG 357 Query: 384 SGLVVPGTGIALHNRGNNFTLEAGHSNVLAGGKRPYHTIIPGFMTRNGQAVGPFGVMGGF 443 SG+VVPGTGI+LHNRG++FT+ H N + KRPYHTIIPGF+TR+G V FGVMGG Sbjct: 358 SGVVVPGTGISLHNRGSDFTVVPRHPNRVGPRKRPYHTIIPGFVTRDGAPVMSFGVMGGM 417 Query: 444 MQPQGHVQMVMNTVDFGLNPQAALDAPRWEWEKGNKVSIEHTTAEHLFRGLGGLGHEVSW 503 MQPQGHVQ+++ D+G NPQAA D PR+ W G +VS E+ + L GH++ Sbjct: 418 MQPQGHVQVLVRIADYGQNPQAACDGPRFRWVNGMRVSFENGFPDSTLDELRQRGHDLVA 477 Query: 504 SGNQLGFGRGQIIWRNDEGVLCGGTEPRTDGCVAA 538 + FG Q IWR D+G L ++PR DG AA Sbjct: 478 VADYSQFGSCQAIWRLDDGYLA-ASDPRRDGQAAA 511 >MT0797 [E] COG0405 Gamma-glutamyltransferase MtC Mycobacterium tuberculosis CDC1551 Length = 512 Score = 459 bits (1180), Expect = e-128, Method: Compositional matrix adjust. Identities = 255/515 (49%), Positives = 322/515 (62%), Gaps = 14/515 (2%) Query: 27 MVATSQPLAAQAGLEVLQRGGNAIDAAIAAAAALTVVEPTANGIGGDAFALVWHGGKLHG 86 +V TSQPLAAQAGL +L GGNA+DAA+A A LTVVEP +NGIG DAF++VW G KLHG Sbjct: 8 VVCTSQPLAAQAGLRMLADGGNAVDAAVATAITLTVVEPVSNGIGSDAFSIVWDGQKLHG 67 Query: 87 LNASGPAPQSISADKLTSAGLKEMPKYGALPVTVPGTPSAWAAMAKRFGKLTLSDSMAGA 146 LNASG +P + + + G +P G VTVPG SAW + RFG+L A Sbjct: 68 LNASGRSPSAWTPEYF---GGNAVPVLGWNSVTVPGAVSAWVELHARFGRLPFETLFEPA 124 Query: 147 ITLAREGFPVSPMVAHAWQVAQQNFKREFKETHFQPWF-DTFCIDGQAPQAGQLWRSAGH 205 I+ R GF VSP VA W F QP F D F G+AP+ G+L+ H Sbjct: 125 ISYGRNGFLVSPTVAAQWAAQVPLFAS-------QPGFADAFMPGGRAPKPGELFTFPDH 177 Query: 206 AATLQAIAEDGAESFYRGALAEQIAAFLQHAGGYLQAADLAAFQAQWVDPIGVNYRGYEV 265 AATL+ IA E FYRG LA ++ A GG ++A DLAA + WVD I YRGY + Sbjct: 178 AATLEKIAATNGEEFYRGELAAKLEAHSAANGGVMRADDLAAHRVDWVDTITGTYRGYTI 237 Query: 266 WEIPPNGHGMVALMALNLLKAYDFTE--RDTLATYHRQIEAIKLAYADGLAHIADPAHMK 323 +IPPNG G+VAL+AL +L+ +D + D+ + H QIEA+KLA+AD A +AD +M Sbjct: 238 HQIPPNGQGIVALIALGILEHFDMSSWSVDSAESVHVQIEALKLAFADAQACVADIDYMP 297 Query: 324 VTVQQLLSDAYADERRQLIGPRATLPVAGDPSRGGTVYLCTADAEGNMVSFIQSNYMGFG 383 V ++LL Y +R LI P+ +P A RGGTVYL ADA G MVS IQSNY+GFG Sbjct: 298 VHPKRLLDKEYLRQRATLIDPKRAMPAATGIPRGGTVYLAAADAAGMMVSMIQSNYLGFG 357 Query: 384 SGLVVPGTGIALHNRGNNFTLEAGHSNVLAGGKRPYHTIIPGFMTRNGQAVGPFGVMGGF 443 SG+VVPGTGI+LHNRG++FT+ H N + KRPYHTIIPGF+TR+G V FGVMGG Sbjct: 358 SGVVVPGTGISLHNRGSDFTVVPRHPNRVGPRKRPYHTIIPGFVTRDGAPVMSFGVMGGM 417 Query: 444 MQPQGHVQMVMNTVDFGLNPQAALDAPRWEWEKGNKVSIEHTTAEHLFRGLGGLGHEVSW 503 MQPQGHVQ+++ D+G NPQAA D PR+ W G +VS E+ + L GH++ Sbjct: 418 MQPQGHVQVLVRIADYGQNPQAACDGPRFRWVNGMRVSFENGFPDSTLDELRQRGHDLVA 477 Query: 504 SGNQLGFGRGQIIWRNDEGVLCGGTEPRTDGCVAA 538 + FG Q IWR D+G L ++PR DG AA Sbjct: 478 VADYSQFGSCQAIWRLDDGYLA-ASDPRRDGQAAA 511