BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1694.p (437 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2352 [GEPR] COG0477 Permeases of the major facilitator superf... 419 e-117 YPO2237 [GEPR] COG0477 Permeases of the major facilitator superf... 387 e-107 RSp1572 [GEPR] COG0477 Permeases of the major facilitator superf... 378 e-104 BMEII1096 [GEPR] COG0477 Permeases of the major facilitator supe... 353 4e-97 PA4126 [GEPR] COG0477 Permeases of the major facilitator superfa... 327 3e-89 >RSc2352 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 442 Score = 419 bits (1077), Expect = e-117, Method: Compositional matrix adjust. Identities = 227/427 (53%), Positives = 306/427 (71%), Gaps = 3/427 (0%) Query: 5 PSAATTAAPPGSAAAPLEATYGKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFS 64 PSA A PP SA+ EATY K++WRLIPFL+ +V+A++DRVNVGFAKLQML DL+FS Sbjct: 10 PSAG--ALPPQSASGFEEATYRKVSWRLIPFLLLCYVVAYLDRVNVGFAKLQMLNDLKFS 67 Query: 65 EAVYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVSTPTSFYV 124 E VYGLGAGIFFIGYFLFEVPSN++L ++GAR +ARI I WGL S AM +V+TP FYV Sbjct: 68 ETVYGLGAGIFFIGYFLFEVPSNVILHRVGARMWIARIMISWGLISAAMMFVTTPAMFYV 127 Query: 125 LRFLLGIFEAGFFPGVVLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGFIMSRMEG 184 +RFLLG+ EAGFFPG++LYLTYW+PA+RR R FMT+ A++G +GGPI+G+ + G Sbjct: 128 MRFLLGLAEAGFFPGIILYLTYWYPAERRGRTTTFFMTAVALSGVIGGPISGWALKTFGG 187 Query: 185 VGHLANWQWLFIIEGIPSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQALALENSAPGK 244 V LA WQW+F+IEGIPS++ G VLA+L + ++A+WL++ EK +T+ +A E A + Sbjct: 188 VYGLAGWQWMFLIEGIPSVVIGLCVLAYLDNRISHARWLTDEEKALLTRNIAAEE-AQKE 246 Query: 245 HFSFKDACSNYRVWICAAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFVAG 304 ++ RVW+ + +YF V G ++FW P++IK+ GV L +GL++AIP+ A Sbjct: 247 DAPIAAIMASPRVWLMSLIYFSFVMGLYGVSFWLPTLIKQTGVADPLSVGLLTAIPYGAA 306 Query: 305 TLAMIWNGFHSDKTGERRLHSAMATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAF 364 +AM+ +D+T ERR H A+ L IGLV + + N TLA+ +LTL +GIL Sbjct: 307 VVAMVLVARSADRTRERRWHIAIPALAGAIGLVLSAVWHTNTTLAMAALTLGTMGILTTL 366 Query: 365 PVFWSIPGAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALEF 424 P+FWS+P AFLAGT AA GIALINS+GNLAGF++PY +G LK +T S SG+Y +AA Sbjct: 367 PLFWSLPTAFLAGTGAAAGIALINSLGNLAGFLSPYAVGWLKDTTRSTDSGMYLLAASMV 426 Query: 425 LASFLVV 431 L + L + Sbjct: 427 LGALLTL 433 >YPO2237 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 436 Score = 387 bits (995), Expect = e-107, Method: Compositional matrix adjust. Identities = 202/433 (46%), Positives = 286/433 (66%), Gaps = 2/433 (0%) Query: 4 SPSAATTAAPPGSAAAPLEATYGKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQF 63 S S+ + + P A Y K W L+P L+ +VL ++DRVNVGFAKLQM DLQF Sbjct: 2 SESSTESLSQPTQLQEENNA-YRKTVWHLLPLLMLCYVLNYLDRVNVGFAKLQMADDLQF 60 Query: 64 SEAVYGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVSTPTSFY 123 S+ VYGLGAG+FFIGYF E+PSNL+L ++GAR +ARI I WG+ S MA+V+TP SFY Sbjct: 61 SDTVYGLGAGMFFIGYFFLEIPSNLILHRVGARLWIARIMITWGIISACMAFVTTPMSFY 120 Query: 124 VLRFLLGIFEAGFFPGVVLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGFIMSRME 183 V+RFLLG+ EAGFFPG++LY++YWFP+ RR RV GLF+ S ++G +G P++G+IM Sbjct: 121 VMRFLLGVAEAGFFPGIILYISYWFPSHRRGRVYGLFVISVPLSGIIGAPLSGWIMQYFN 180 Query: 184 GVGHLANWQWLFIIEGIPSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQALALENSAPG 243 G A WQW+FI+EGIPS+L G ++ L ++ +A WL++ EK+ + + E +A Sbjct: 181 GFQGYAGWQWMFILEGIPSVLVGILIIYKLKDRITHATWLTDKEKDILQTNIENE-AAHY 239 Query: 244 KHFSFKDACSNYRVWICAAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFVA 303 H +DA RVW+ +YFC++SG TI FW P++I++ GVK L IG ++AIP A Sbjct: 240 AHSRLRDAFLQPRVWLLTLIYFCLISGFYTIGFWLPTLIRDSGVKDILSIGFLTAIPSAA 299 Query: 304 GTLAMIWNGFHSDKTGERRLHSAMATLIACIGLVATGMTLGNATLALCSLTLAAIGILAA 363 + MI +D+ ERR H A+ ++ +G++ + N +A+ LT+ A+G L+ Sbjct: 300 AAVTMIVVSRSADRLRERRWHLALTAVLGAVGIILSTYFSDNIVVAMVCLTIGAMGALST 359 Query: 364 FPVFWSIPGAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALE 423 P+FWS+P AFL G+AAA GIA INS GNL GFVAPYM+G LK T S ++G+ ++ Sbjct: 360 IPLFWSLPTAFLGGSAAAAGIAFINSWGNLGGFVAPYMMGYLKDLTQSTTTGMLIISTTL 419 Query: 424 FLASFLVVVFVKK 436 F+ + LV + K Sbjct: 420 FIGAALVFLIPAK 432 >RSp1572 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 378 bits (971), Expect = e-104, Method: Compositional matrix adjust. Identities = 196/393 (49%), Positives = 266/393 (67%), Gaps = 3/393 (0%) Query: 23 ATYGKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFLF 82 + Y + R++PFL ++ A++DR+N+GFAKLQM DL S+A YGLGAGIFF GY LF Sbjct: 18 SVYSVVNRRILPFLATCYLFAYLDRINIGFAKLQMQNDLALSDAAYGLGAGIFFFGYMLF 77 Query: 83 EVPSNLLLEKIGARKTLARITILWGLASMAMAYVSTPTSFYVLRFLLGIFEAGFFPGVVL 142 EVPSNLLL KIGAR+TL+RI ILWG+ S +M +V+ +FY LRFLLG+FEAGF PG++ Sbjct: 78 EVPSNLLLVKIGARRTLSRILILWGIVSASMLFVTDVWTFYALRFLLGVFEAGFAPGMIY 137 Query: 143 YLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGFIMSRMEGVGHLANWQWLFIIEGIPS 202 YLT W+P +R AR + + + + G +GGP + +IM G G LA WQW+F+ EGIPS Sbjct: 138 YLTQWYPGERMARAMAVVLGAAPLGGVIGGPASTWIMGHFAGAGGLAGWQWMFLAEGIPS 197 Query: 203 ILAGFAVLAWLPEKPANAKWLSEAEKNAVTQALALENSAPGKHFSFKDACSNYRVWICAA 262 IL G A +L +KPA+A+WL++A+K + +A +APG+ SF A + ++++ AA Sbjct: 198 ILLGIAAYGYLVDKPADARWLTDAQKAVIAGDIA--RAAPGQASSFGKALTEPKLYVLAA 255 Query: 263 VYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFVAGTLAMIWNGFHSDKTGERR 322 YFC++ G + FW PSI+K G+ QIGL SAIP +A +AM G SD+ GER Sbjct: 256 AYFCLICGVYAVGFWLPSILKSAGLSDLFQIGLYSAIPNLAMIVAMYALGRRSDRRGERH 315 Query: 323 LHSAMATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVFWSIPGAFLAGTAAAG 382 LHSA+ ++ GL+A + AL S+TLA+ I A++ VFW+IP L GTAAAG Sbjct: 316 LHSAITAVLGA-GLLAWAAYATSFPAALISITLASAAIFASYSVFWAIPQQHLKGTAAAG 374 Query: 383 GIALINSIGNLAGFVAPYMIGALKTSTGSLSSG 415 GIALINSIG GF +P +IG K +TGSL +G Sbjct: 375 GIALINSIGLFGGFFSPTLIGWTKEATGSLQAG 407 >BMEII1096 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 451 Score = 353 bits (907), Expect = 4e-97, Method: Compositional matrix adjust. Identities = 184/408 (45%), Positives = 264/408 (64%), Gaps = 1/408 (0%) Query: 24 TYGKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAVYGLGAGIFFIGYFLFE 83 TY K+A+R+IP L+ +++A++DRVNVGFAKLQM ++L FSEA+YGLGAG+FFIGYF FE Sbjct: 36 TYRKVAFRIIPLLMICYIIAYLDRVNVGFAKLQMSEELGFSEAIYGLGAGLFFIGYFFFE 95 Query: 84 VPSNLLLEKIGARKTLARITILWGLASMAMAYVSTPTSFYVLRFLLGIFEAGFFPGVVLY 143 +PSN+LL K+GAR +ARI I WGL S A+V T FY+LRFLLG EAGF+PGV+LY Sbjct: 96 IPSNILLHKLGARLWIARIMITWGLLSALFAFVQTEWQFYILRFLLGAAEAGFYPGVILY 155 Query: 144 LTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGFIMSRMEGVGHLANWQWLFIIEGIPSI 203 LTYWFP+ RR + LF AG G P++G+IM + WQW+F++E IP++ Sbjct: 156 LTYWFPSHRRGNMFALFQAGSPAAGIFGNPLSGWIMDQFHDTAGWQGWQWMFVLEAIPAV 215 Query: 204 LAGFAVLAWLPEKPANAKWLSEAEKNAVTQALALENSAPGKHFSFKDACSNYRVWICAAV 263 + G +L +L AKWL+E EK +++ + ++ S N +W+ + Sbjct: 216 VLGVVILLYLDNSVKAAKWLTEEEKAIISRDIEADSKGKAASHSLMSLVKNPMLWVMMLI 275 Query: 264 YFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFVAGTLAMIWNGFHSDKTGERRL 323 YFC V G + W P++I+ GV N+ IGL+ AIPF+ +AM+ +D ERR Sbjct: 276 YFCFVMGQHGLTLWMPTLIRASGVTSNVTIGLLGAIPFICAIIAMVIFSRSADHYRERRW 335 Query: 324 HSAMATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVFWSIPGAFLAGTAAAGG 383 H + L+ +G V + N T+++ L++AA G+LA P+FWS+P A L+G AAA G Sbjct: 336 HLVVPALLGAVGFVVAA-SATNTTVSIIFLSMAAAGVLACAPLFWSLPTAILSGAAAAAG 394 Query: 384 IALINSIGNLAGFVAPYMIGALKTSTGSLSSGLYFVAALEFLASFLVV 431 IALINS+ NLAGF++PYM+G ++ +T S G+Y +A L + +V+ Sbjct: 395 IALINSVANLAGFISPYMVGIIRDATHSSELGMYVLAGFLILGAAIVL 442 >PA4126 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 434 Score = 327 bits (839), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 180/402 (44%), Positives = 260/402 (64%), Gaps = 2/402 (0%) Query: 9 TTAAPPGSAAAPL-EATYGKIAWRLIPFLVFLFVLAWIDRVNVGFAKLQMLQDLQFSEAV 67 +TA+ S PL ++T+ ++ WRL+P L+ +V A +DR+N+GFAKLQM DL FS+ V Sbjct: 2 STASTLNSTTLPLSDSTHDRVTWRLMPLLLVCYVFAHLDRINIGFAKLQMSADLHFSDTV 61 Query: 68 YGLGAGIFFIGYFLFEVPSNLLLEKIGARKTLARITILWGLASMAMAYVSTPTSFYVLRF 127 YGLGAG+FFI Y LF +PSNL+LE+IG R+ +A + ++WG S AM V T FY+LRF Sbjct: 62 YGLGAGLFFIAYALFGLPSNLMLERIGPRRWIACLMLVWGCLSTAMLLVETARGFYLLRF 121 Query: 128 LLGIFEAGFFPGVVLYLTYWFPAQRRARVNGLFMTSFAIAGAVGGPIAGFIMSRMEGVGH 187 LLG+ EAGFFPG+++YL WFPA+RR ++ LF + +AG +GGP++G+I+ Sbjct: 122 LLGVAEAGFFPGILVYLNRWFPARRRGQITALFAIAVPMAGVIGGPLSGWILEGFHDALG 181 Query: 188 LANWQWLFIIEGIPSILAGFAVLAWLPEKPANAKWLSEAEKNAVTQALALENSAPGKHFS 247 L WQW+F+IEG+P +L G V LPE WLS+ +K+ + + LA E S Sbjct: 182 LRGWQWMFLIEGLPVVLLGVVVWCSLPESFERVTWLSDEQKHLLREELAGEEQRKTIT-S 240 Query: 248 FKDACSNYRVWICAAVYFCVVSGNATIAFWAPSIIKEIGVKGNLQIGLISAIPFVAGTLA 307 F SN +VW+ A+YF V+ TIAFW PS+I G+ + +IG++SA+P++AG Sbjct: 241 FSGIFSNPQVWLLVAIYFAVMLAVNTIAFWMPSLIHGAGIAQDSRIGMLSAVPYLAGCAF 300 Query: 308 MIWNGFHSDKTGERRLHSAMATLIACIGLVATGMTLGNATLALCSLTLAAIGILAAFPVF 367 MI+ G SD+ ERR H + L+A GL + +A L + L +A +G AA P+F Sbjct: 301 MIFIGRSSDRLRERRWHLGIPLLMAAAGLSLAALAPTSAWLVMGGLVIAGMGASAALPMF 360 Query: 368 WSIPGAFLAGTAAAGGIALINSIGNLAGFVAPYMIGALKTST 409 W +P AFL+ A GIALI+S G++A F+APY+IG ++ +T Sbjct: 361 WQLPPAFLSSATLAAGIALISSFGSIAAFLAPYLIGWMRDTT 402