BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1691.p (662 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0976 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, ... 1099 0.0 NMA1941 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, ... 857 0.0 NMB1682 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, ... 857 0.0 VC2431 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, t... 636 0.0 XF1286 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, t... 631 e-180 >RSc0976 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit Rso Ralstonia solanacearum Length = 661 Score = 1099 bits (2843), Expect = 0.0, Method: Compositional matrix adjust. Identities = 537/659 (81%), Positives = 585/659 (88%), Gaps = 4/659 (0%) Query: 7 TPSDYSESSIRVLKGLEPVKQRPGMYTRTENPLHILQEVIDNASDEALGGYGKSIIVTIN 66 TP YSE+SI+VLKGLEPVKQRPGMYTRT+NPLHI+QEVIDNA+DEALGGYGK I VT++ Sbjct: 4 TPQ-YSEASIKVLKGLEPVKQRPGMYTRTDNPLHIVQEVIDNAADEALGGYGKWIQVTLH 62 Query: 67 ADGSVSVEDDGRGIPVGLHPEEKVPTVEIVFTRLHAGGKFDKGSGGAYAFSGGLHGVGVS 126 DGSVSVED+ RGIPVG+HPEE VP VEIVFTRLHAGGKFDKG GGAYAFSGGLHGVGVS Sbjct: 63 KDGSVSVEDEARGIPVGIHPEEGVPVVEIVFTRLHAGGKFDKGRGGAYAFSGGLHGVGVS 122 Query: 127 VTNALATRLEITVWREGGVHTLAFSGGDVIEKLKSRPATREDKKSGTRVTVWPDAKYFDS 186 VTNAL+TRLE+ VWR+G V TLAFSGGDVIE L +R A R +KK+GTRV VWPD KYFDS Sbjct: 123 VTNALSTRLEVAVWRDGSVSTLAFSGGDVIEALATRRAERGEKKNGTRVRVWPDGKYFDS 182 Query: 187 ATIPLGELQRLLRSKAVLLPGVKVTLINAKNGDTQSWQYDQGLRGYLMEQLAQSGSGETL 246 IP ELQRLLRSKAVLLPGVKV+L K+G+T WQYDQGLRGYL+E LAQ + + Sbjct: 183 ENIPQAELQRLLRSKAVLLPGVKVSLTIEKSGETLEWQYDQGLRGYLIESLAQGSGADPV 242 Query: 247 IPLFEGEQFAGKD---TDGFAEGEGASWVVAWTEEGAVVRESYVNLIPTSNGGTHESGLR 303 IPLFEGE FA D +GFA GEGASWVVAWT+EG+ VRESYVNLIPT GGTHESGLR Sbjct: 243 IPLFEGEHFADPDRPGEEGFAFGEGASWVVAWTDEGSPVRESYVNLIPTPAGGTHESGLR 302 Query: 304 EGLFSAVKSFAEMHSLLPKGVKLLAEDVFARVSFVLSAKVLDPQFQGQIKERLNSRDAVR 363 EGLF AVKSF EMH+L PKGVKL+ EDVFAR SFVLSAKVLDPQFQGQIKERLNSRDAVR Sbjct: 303 EGLFQAVKSFVEMHALCPKGVKLMPEDVFARASFVLSAKVLDPQFQGQIKERLNSRDAVR 362 Query: 364 LVAGFSRPALELWLNQHVEYGKKLAELVIKQAQSRLRSAQKVEKKKSSGVAVLPGKLTDC 423 LV+ FSRPALELWLNQHVE+GKKLAELVI+QAQ+R R+AQKVEKKK SGVAVLPGKLTDC Sbjct: 363 LVSTFSRPALELWLNQHVEFGKKLAELVIRQAQARTRAAQKVEKKKGSGVAVLPGKLTDC 422 Query: 424 ESSDVTRNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNAWETERDRLYANNEIHDI 483 ES DV+RNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLN WETERDRL+ANNE+HDI Sbjct: 423 ESDDVSRNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNTWETERDRLFANNEVHDI 482 Query: 484 AVAIGVDPHGINDTPDLSGLRYGKICILSDADVDGSHIQVLLLTLFFRHFPKLIENGNIC 543 AVAIGVDPHG D+ DLSGLRYGKICILSDADVDG+HIQVLLLTLFF+HFP+LI GN+C Sbjct: 483 AVAIGVDPHGPADSVDLSGLRYGKICILSDADVDGAHIQVLLLTLFFKHFPQLIGRGNVC 542 Query: 544 VARPPLYRVDAPARGKKPVQKLYALDDGELDAIEDKLRKDGLKEGAWSISRFKGLGEMNA 603 VARPPLYRVDAPARGKKP QKLYALDDGEL+AIEDKLRK+GLKEG+W ISRFKGLGEM+A Sbjct: 543 VARPPLYRVDAPARGKKPAQKLYALDDGELEAIEDKLRKEGLKEGSWQISRFKGLGEMSA 602 Query: 604 EQLWETTMNPDTRRLLPISFGEPGVQTSEERFNMLMGKGEAASRRAWIEEHGNEAEADI 662 EQLWETTMNPDTRRLLP+S GEPG + + NMLMGKGEA +RR W+E GNE EADI Sbjct: 603 EQLWETTMNPDTRRLLPVSIGEPGAEQTVHVMNMLMGKGEAGARRTWLEARGNEVEADI 661 >NMA1941 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit NmA Neisseria meningitidis Z2491 Length = 661 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/661 (64%), Positives = 526/661 (79%), Gaps = 11/661 (1%) Query: 9 SDYSESSIRVLKGLEPVKQRPGMYTRTENPLHILQEVIDNASDEALGGYGKSIIVTINAD 68 + YSESSI VLKGLEPVK+RPGMYTRT++P HI QEVIDNA+DEALGG+ +I V I+ D Sbjct: 5 NQYSESSITVLKGLEPVKERPGMYTRTDSPTHICQEVIDNAADEALGGFATAIDVQIHED 64 Query: 69 GSVSVEDDGRGIPVGLHPEEKVPTVEIVFTRLHAGGKFDKGSGG-AYAFSGGLHGVGVSV 127 GS+SV D+GRGIPVGLHPEE VP VE+VFTRLHAGGKF+K GG AYAFSGGLHGVGVSV Sbjct: 65 GSLSVRDNGRGIPVGLHPEEGVPVVELVFTRLHAGGKFNKKDGGSAYAFSGGLHGVGVSV 124 Query: 128 TNALATRLEITVWREGGVHTLAFSGGDVIEKLKSRPATREDKKSGTRVTVWPDAKYFDSA 187 TNAL+TRLE+TV REG +H + F+GGDV+E L ++ K SGT V VWPD KYF+S Sbjct: 125 TNALSTRLEVTVKREGKIHRIVFAGGDVVEPL-AQVGKCAVKDSGTEVRVWPDGKYFESP 183 Query: 188 TIPLGELQRLLRSKAVLLPGVKVTLINAKNGD----TQSWQYDQGLRGYLMEQLAQSGSG 243 + EL+RLLR+KAVLLPGV+V+L G+ TQ+W Y GL+ YL + +A + Sbjct: 184 NYSIPELERLLRAKAVLLPGVRVSLTRPVKGEDEAHTQTWHYPDGLKSYLTDLIADA--- 240 Query: 244 ETLIPLFEGEQFAGKDTDG-FAEGEGASWVVAWTEEGAVVRESYVNLIPTSNGGTHESGL 302 + +PLF E + + +G F+ GEGA++ + W EEG+ ESYVNLIPT GGTHE+GL Sbjct: 241 QEAVPLFSCENYISDEHNGDFSIGEGAAFALTWLEEGSCANESYVNLIPTPLGGTHEAGL 300 Query: 303 REGLFSAVKSFAEMHSLLPKGVKLLAEDVFARVSFVLSAKVLDPQFQGQIKERLNSRDAV 362 ++ +F+AV +F +H+LLP+GVK+ ++DVF + +FVLSA+VLDPQFQGQ K++L +RDA+ Sbjct: 301 KQAVFNAVSNFINLHNLLPRGVKVQSDDVFGKTAFVLSARVLDPQFQGQTKDKLTNRDAL 360 Query: 363 RLVAGFSRPALELWLNQHVEYGKKLAELVIKQAQSRLRSAQKVEKKKSSGVAVLPGKLTD 422 +LVA S LELWLNQ+V++GKK+AEL I+QAQ+R+RS +K+EKKK SGVAVLPGKLTD Sbjct: 361 KLVATVSGDPLELWLNQNVDFGKKIAELAIRQAQARMRSVKKIEKKKGSGVAVLPGKLTD 420 Query: 423 CESSDVTRNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNAWETERDRLYANNEIHD 482 CES D+ NELFLVEGDSAGGSAK+ RDK QAILPLRGKVLN++E D+L+ N EIHD Sbjct: 421 CESEDIRENELFLVEGDSAGGSAKLARDKATQAILPLRGKVLNSFEVHPDQLFGNAEIHD 480 Query: 483 IAVAIGVDPHGINDTPDLSGLRYGKICILSDADVDGSHIQVLLLTLFFRHFPKLIENGNI 542 I+VAIGVDPHGIND PDLSGLRYGKI ILSDADVDGSHIQVLLLTLF+RHFPKL+ +G+I Sbjct: 481 ISVAIGVDPHGINDHPDLSGLRYGKIAILSDADVDGSHIQVLLLTLFYRHFPKLVADGHI 540 Query: 543 CVARPPLYRVDAPARGK-KPVQKLYALDDGELDAIEDKLRKDGLKEGAWSISRFKGLGEM 601 VA+PPL+RVD A+GK KP +K YALD ELD I ++L+K+G+KE A+SISRFKGLGEM Sbjct: 541 YVAQPPLFRVDVNAQGKSKPARKFYALDQNELDGILERLQKEGVKETAYSISRFKGLGEM 600 Query: 602 NAEQLWETTMNPDTRRLLPISFGEPGVQTSEERFNMLMGKGEAASRRAWIEEHGNEAEAD 661 N +QL +TTM+PDTRRLL + E + + F LMGKGEAA+RRAW+E G+ AE D Sbjct: 601 NPDQLKDTTMHPDTRRLLQVQIPEGADDETRDIFFKLMGKGEAAARRAWMEREGDTAELD 660 Query: 662 I 662 I Sbjct: 661 I 661 >NMB1682 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit Nme Neisseria meningitidis MC58 Length = 661 Score = 857 bits (2215), Expect = 0.0, Method: Compositional matrix adjust. Identities = 425/661 (64%), Positives = 526/661 (79%), Gaps = 11/661 (1%) Query: 9 SDYSESSIRVLKGLEPVKQRPGMYTRTENPLHILQEVIDNASDEALGGYGKSIIVTINAD 68 + YSESSI VLKGLEPVK+RPGMYTRT++P HI QEVIDNASDEALGG+ +I V I+ D Sbjct: 5 NQYSESSITVLKGLEPVKERPGMYTRTDSPTHICQEVIDNASDEALGGFATAIDVQIHED 64 Query: 69 GSVSVEDDGRGIPVGLHPEEKVPTVEIVFTRLHAGGKFDKGSGG-AYAFSGGLHGVGVSV 127 GS+SV D+GRGIPVGLHPEE V VE+VFTRLHAGGKF+K GG AYAFSGGLHGVGVSV Sbjct: 65 GSLSVHDNGRGIPVGLHPEEGVSVVELVFTRLHAGGKFNKKDGGSAYAFSGGLHGVGVSV 124 Query: 128 TNALATRLEITVWREGGVHTLAFSGGDVIEKLKSRPATREDKKSGTRVTVWPDAKYFDSA 187 TNAL+TRLE+TV REG +H + F+GGDV+E L ++ K SGT V VWPD KYF+S Sbjct: 125 TNALSTRLEVTVKREGKIHRIVFAGGDVVEPL-AQVGKCAVKDSGTEVRVWPDGKYFESP 183 Query: 188 TIPLGELQRLLRSKAVLLPGVKVTLINAKNGD----TQSWQYDQGLRGYLMEQLAQSGSG 243 + EL+RLLR+KAVLLPGV+V+L G+ TQ+W Y GL+ YL + +A + Sbjct: 184 NYSIPELERLLRAKAVLLPGVRVSLTRPVKGEDEAHTQTWHYPDGLKSYLTDLIADA--- 240 Query: 244 ETLIPLFEGEQFAGKDTDG-FAEGEGASWVVAWTEEGAVVRESYVNLIPTSNGGTHESGL 302 + +PLF E + + +G F+ GEGA++ + W EEG+ ESYVNLIPT GGTHE+GL Sbjct: 241 QEAVPLFSCENYISDEHNGDFSIGEGAAFALTWLEEGSCANESYVNLIPTPLGGTHEAGL 300 Query: 303 REGLFSAVKSFAEMHSLLPKGVKLLAEDVFARVSFVLSAKVLDPQFQGQIKERLNSRDAV 362 ++ +F+AV +F +H+LLP+GVK+ ++DVF + +FVLSA+VLDPQFQGQ K++L +RDA+ Sbjct: 301 KQAVFNAVNNFINLHNLLPRGVKVQSDDVFGKTAFVLSARVLDPQFQGQTKDKLTNRDAL 360 Query: 363 RLVAGFSRPALELWLNQHVEYGKKLAELVIKQAQSRLRSAQKVEKKKSSGVAVLPGKLTD 422 +LVA S LELWLNQ+V++GKK+AEL I+QAQ+R+RS +K+EKKK SGVAVLPGKLTD Sbjct: 361 KLVATVSGDPLELWLNQNVDFGKKIAELAIRQAQARMRSVKKIEKKKGSGVAVLPGKLTD 420 Query: 423 CESSDVTRNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNAWETERDRLYANNEIHD 482 CES D+ NELFLVEGDSAGGSAK+ RDK QAILPLRGKVLN++E D+L+ N EIHD Sbjct: 421 CESEDIRENELFLVEGDSAGGSAKLARDKATQAILPLRGKVLNSFEVHPDQLFGNAEIHD 480 Query: 483 IAVAIGVDPHGINDTPDLSGLRYGKICILSDADVDGSHIQVLLLTLFFRHFPKLIENGNI 542 I+VAIGVDPHGIND PDLSGLRYGKI ILSDADVDGSHIQVLLLTLF+RHFPKL+ +G+I Sbjct: 481 ISVAIGVDPHGINDHPDLSGLRYGKIAILSDADVDGSHIQVLLLTLFYRHFPKLVADGHI 540 Query: 543 CVARPPLYRVDAPARGK-KPVQKLYALDDGELDAIEDKLRKDGLKEGAWSISRFKGLGEM 601 VA+PPL+RVD A+GK KP +K YALD ELD+I ++L+K+G+KE A+SISRFKGLGEM Sbjct: 541 YVAQPPLFRVDVNAQGKSKPARKFYALDQNELDSILERLQKEGVKETAYSISRFKGLGEM 600 Query: 602 NAEQLWETTMNPDTRRLLPISFGEPGVQTSEERFNMLMGKGEAASRRAWIEEHGNEAEAD 661 N +QL +TTM+PDTRRLL + E + + F LMGKGEAA+RRAW+E G+ AE D Sbjct: 601 NPDQLKDTTMHPDTRRLLQVQIPEGADDETRDIFVKLMGKGEAAARRAWMEREGDTAELD 660 Query: 662 I 662 I Sbjct: 661 I 661 >VC2431 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit Vch Vibrio cholerae Length = 626 Score = 636 bits (1640), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/650 (50%), Positives = 438/650 (67%), Gaps = 30/650 (4%) Query: 11 YSESSIRVLKGLEPVKQRPGMYTRTENPLHILQEVIDNASDEALGGYGKSIIVTINADGS 70 Y+ +I VL GLEPV++RPGMYT T P H+ QEVIDN+ DEAL GY I V ++AD S Sbjct: 5 YNAGAIEVLNGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGYASKIQVILHADQS 64 Query: 71 VSVEDDGRGIPVGLHPEEKVPTVEIVFTRLHAGGKFDKGSGGAYAFSGGLHGVGVSVTNA 130 + V DDGRG+PV +HPEEKV VE++ +LHAGGKF S Y FSGGLHGVG+SV NA Sbjct: 65 LEVIDDGRGMPVDIHPEEKVSGVELILCKLHAGGKF---SNKNYQFSGGLHGVGISVVNA 121 Query: 131 LATRLEITVWREGGVHTLAFSGGDVIEKLKSRPATREDKKSGTRVTVWPDAKYFDSATIP 190 L+ R+E+ V R+G V+ +AF GD + +L + T + +GT V WPD KYFDS Sbjct: 122 LSKRVEVAVRRDGQVYEIAFEHGDKVTEL-TVTGTCGRRNTGTSVHFWPDTKYFDSPNFS 180 Query: 191 LGELQRLLRSKAVLLPGVKVTLINAKNGDTQSWQYDQGLRGYLMEQLAQSGSGETLIPLF 250 + L LR+KAVL PG+++ + N + W Y+ GL+ YL E + G TL+P Sbjct: 181 VSRLINNLRAKAVLCPGLEIIFTDKVNNNEHRWLYEDGLKDYLAEGV----KGYTLLP-- 234 Query: 251 EGEQFAGKDTDGFAEGEGASWVVAWTEEGA-VVRESYVNLIPTSNGGTHESGLREGLFSA 309 E F G+ T A+ E A+W V W EG ++ ESYVNLIPT+ GGTH +GLR+GL A Sbjct: 235 -EEPFTGEFT---AQTEAATWAVIWLPEGGELITESYVNLIPTAQGGTHVNGLRQGLLDA 290 Query: 310 VKSFAEMHSLLPKGVKLLAEDVFARVSFVLSAKVLDPQFQGQIKERLNSRDAVRLVAGFS 369 ++ F E +LLP+GVKL EDVF R ++VLS K+ DPQF GQ KERL+SR + V+G Sbjct: 291 MREFCEFRNLLPRGVKLTGEDVFDRCAYVLSIKMQDPQFAGQTKERLSSRQSAAFVSGVV 350 Query: 370 RPALELWLNQHVEYGKKLAELVIKQAQSRLRSAQKVEKKKSSGVAVLPGKLTDCESSDVT 429 + A LWLN+ + ++LAE+ I A SR+R+++KV +KK + LPGKLTDC D+ Sbjct: 351 KDAFSLWLNEKPQLAEQLAEVCIANAHSRMRASKKVVRKKIASGPALPGKLTDCTVQDLN 410 Query: 430 RNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNAWETERDRLYANNEIHDIAVAIGV 489 R ELFLVEGDSAGGSAK RD+EFQA++PLRGK+LN WE D++ A+ E+HDI+VA+G+ Sbjct: 411 RTELFLVEGDSAGGSAKQARDREFQAVMPLRGKILNTWEVSADQVLASQEVHDISVALGI 470 Query: 490 DPHGINDTPDLSGLRYGKICILSDADVDGSHIQVLLLTLFFRHFPKLIENGNICVARPPL 549 DP D+ +L LRYGK+CIL+DAD DG HI LL LF RHF L++ G++ VA PPL Sbjct: 471 DP----DSDNLEALRYGKVCILADADSDGLHIATLLCALFTRHFRALVKAGHVYVAMPPL 526 Query: 550 YRVDAPARGKKPVQKLYALDDGELDAIEDKLRKDGLKEGAWSISRFKGLGEMNAEQLWET 609 YR+D GK + YALDD E + + ++L + K+ ++ RFKGLGEMN QL ET Sbjct: 527 YRIDC---GK---EVFYALDDQEKEGVLERLSQ---KKAKVNVQRFKGLGEMNPLQLRET 577 Query: 610 TMNPDTRRLLPISFGEPGVQTSEERFNMLMGKGEAASRRAWIEEHGNEAE 659 TM+P+TRRL+ ++ + + ++E +ML+GK A RRAW++ +G+ AE Sbjct: 578 TMDPNTRRLVQLTIDD--AEATDEMMDMLLGKKRADDRRAWLQRNGDMAE 625 >XF1286 [L] COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit Xfa Xylella fastidiosa 9a5c Length = 629 Score = 631 bits (1627), Expect = e-180, Method: Compositional matrix adjust. Identities = 330/657 (50%), Positives = 437/657 (66%), Gaps = 33/657 (5%) Query: 9 SDYSESSIRVLKGLEPVKQRPGMYTRTENPLHILQEVIDNASDEALGGYGKSIIVTINAD 68 S Y+ + I VL GL+PVK+RPGMYT T P H+ QEVIDN+ DEAL GY I VT+ D Sbjct: 3 SRYNAADIEVLTGLDPVKRRPGMYTDTTRPNHLAQEVIDNSVDEALAGYANRIEVTLYKD 62 Query: 69 GSVSVEDDGRGIPVGLHPEEKVPTVEIVFTRLHAGGKFDKGSGGAYAFSGGLHGVGVSVT 128 GS V D+GRG+PV +HPEEK+P VE++ TRLHAGGKF S Y FSGGLHGVGVSV Sbjct: 63 GSCEVADNGRGMPVDIHPEEKIPGVELILTRLHAGGKF---SNRNYTFSGGLHGVGVSVV 119 Query: 129 NALATRLEITVWREGGVHTLAFSGGDVIEKLKSRPATREDKKSGTRVTVWPDAKYFDSAT 188 NAL++++++ + REG H + F G + KLK T K +GTR+ WPD+KYFD+ Sbjct: 120 NALSSKVDLFIKREGSEHHMEFREGFAVSKLKVL-GTVSKKNTGTRLRFWPDSKYFDTPK 178 Query: 189 IPLGELQRLLRSKAVLLPGVKVTLINAKNGDTQSWQYDQGLRGYLMEQLAQSGSGETLIP 248 + L+ LLR+KAVL PG+ V L+ G+ +W + GLR YL ++ +S Sbjct: 179 FNVRVLRHLLRAKAVLCPGLTVELLEEATGEINTWHFKDGLRDYLKGEMTES-------E 231 Query: 249 LFEGEQFAG---KDTDGFAEGEGASWVVAWTEEGAVVRESYVNLIPTSNGGTHESGLREG 305 L E F G KDT E W VAW EG + +ESYVNLIPT GTH +GLR G Sbjct: 232 LLPAELFIGCLKKDT------EVVDWAVAWVPEGELTQESYVNLIPTPQHGTHVNGLRSG 285 Query: 306 LFSAVKSFAEMHSLLPKGVKLLAEDVFARVSFVLSAKVLDPQFQGQIKERLNSRDAVRLV 365 L A++ F + +LLP+G+KL EDV+ RV+FVLS K+ DPQF GQ KERL+SR A + Sbjct: 286 LTDALREFCDFRNLLPRGIKLAPEDVWDRVTFVLSLKMSDPQFSGQTKERLSSRQAAGFI 345 Query: 366 AGFSRPALELWLNQHVEYGKKLAELVIKQAQSRLRSAQKVEKKKSSGVAVLPGKLTDCES 425 G A LWLNQ+V+ G+++A++ I++A +RL++ ++V +KK + LPGKL DC S Sbjct: 346 EGTVHDAFSLWLNQNVDIGEQIAQIAIERASARLKTEKQVTRKKITHGPALPGKLADCIS 405 Query: 426 SDVTRNELFLVEGDSAGGSAKMGRDKEFQAILPLRGKVLNAWETERDRLYANNEIHDIAV 485 D++R ELFLVEGDSAGGSAK RDK+FQAILPLRGK+LN WE + A++E+H++A+ Sbjct: 406 LDLSRTELFLVEGDSAGGSAKQARDKDFQAILPLRGKILNTWEVASGNVLASDEVHNLAI 465 Query: 486 AIGVDPHGINDTPDLSGLRYGKICILSDADVDGSHIQVLLLTLFFRHFPKLIENGNICVA 545 AIG DP N LSGLRYGK+ IL+DAD DG HI LL LF +HFP L+ G++ VA Sbjct: 466 AIGCDPGKDN----LSGLRYGKVVILADADSDGLHIATLLTALFLKHFPALVAAGHVFVA 521 Query: 546 RPPLYRVDAPARGKKPVQKLYALDDGELDAIEDKLRKDGLKEGAWSISRFKGLGEMNAEQ 605 PPL+RVD GK Q YALDD E + +K++++ +K G S++RFKGLGEMN +Q Sbjct: 522 MPPLFRVDV---GK---QVFYALDDEEKTMLLEKIKREKIK-GQVSVTRFKGLGEMNPQQ 574 Query: 606 LWETTMNPDTRRLLPISFGEPGVQTSEERFNMLMGKGEAASRRAWIEEHGNEAEADI 662 L E+T++PDTRRL+ ++ + QT +ML+ K A+ R+ W+E GN A DI Sbjct: 575 LRESTIHPDTRRLVQLTMDD-NTQTC-SLMDMLLAKKRASDRKQWLETKGNLASLDI 629