BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1669.p (315 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0987 [GER] COG0697 Permeases of the drug/metabolite transport... 288 1e-77 SMb20040 [GER] COG0697 Permeases of the drug/metabolite transpor... 234 2e-61 AGc394 [GER] COG0697 Permeases of the drug/metabolite transporte... 224 3e-58 BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transport... 220 3e-57 mll1137 [GER] COG0697 Permeases of the drug/metabolite transport... 215 1e-55 >RSc0987 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 288 bits (737), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 183/312 (58%), Positives = 215/312 (68%), Gaps = 16/312 (5%) Query: 20 TESDASPARH-----ESRGMWLGLVGVAVFSLTLPFTRIAVAELNPAFVAFGRAVVAGLC 74 T S A P H E RG+ LG +GV +FS TLPFTR+AVAEL+ FVA AV+A L Sbjct: 2 TRSTALPLGHAPDHAERRGLLLGFIGVTIFSQTLPFTRMAVAELDATFVALAHAVLASLL 61 Query: 75 ALALLAWIKAP----RPTTQQLRGLIITALGVVVGFPLFSSIAMRHVPAAHGAVVVGLLP 130 ALALLA A RP Q L +TA GVVVGFPLFSS+AMR VPAAHGA++ GLLP Sbjct: 62 ALALLAATGALRAARRPRGGQWGRLAVTAAGVVVGFPLFSSLAMRDVPAAHGAIITGLLP 121 Query: 131 LATALFGALRFGERPSTGFWLAALAGSGIVIAFALREGGGSFHPADFALFAAVLTAAMGY 190 LATALF A ERPS FW ALAGS +V++FAL G G+ H AD+ LFAA++ A+GY Sbjct: 122 LATALFAAWFGRERPSPWFWACALAGSVLVVSFALLRGAGTLHRADWLLFAAMVAGALGY 181 Query: 191 AEGGRLAQSMGGQNVIAWALVVALPVMLPVSLWLGWQYGV-------SASAPAWLAFAYV 243 A GG+L++ +GG IAWALVV+LP +LPV L W G AS AWL AYV Sbjct: 182 AVGGKLSRELGGTQTIAWALVVSLPALLPVVGALAWLPGTHQAAALAQASGHAWLGLAYV 241 Query: 244 SLFSMFIGFFFWYKGLALGGIARVGQVQLLQPFMSLLGAAVIADEALDASNMLFALAVIV 303 S FSMF+GF FWY GLA GG+ARVGQ+QLLQPFM+L+G ++ E LDA MLFALAVI Sbjct: 242 SAFSMFVGFLFWYSGLAAGGVARVGQIQLLQPFMTLIGGWLLLGEPLDAPTMLFALAVIA 301 Query: 304 VVAIGRRMAVRR 315 VV +GRR AVRR Sbjct: 302 VVGLGRRTAVRR 313 >SMb20040 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 286 Score = 234 bits (597), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 131/285 (45%), Positives = 183/285 (64%), Gaps = 1/285 (0%) Query: 29 HESRGMWL-GLVGVAVFSLTLPFTRIAVAELNPAFVAFGRAVVAGLCALALLAWIKAPRP 87 +++ W+ GL+GV +FS +LP TR+AV + +P F+ RA +AG+ A LL + RP Sbjct: 2 NKATSGWMSGLIGVVIFSGSLPATRVAVMDFDPIFLTVARATIAGILAFCLLFAFRERRP 61 Query: 88 TTQQLRGLIITALGVVVGFPLFSSIAMRHVPAAHGAVVVGLLPLATALFGALRFGERPST 147 L L + +LGVVVGFPL +++A+RHV +AH V +GLLPLATA+FG LR GERP Sbjct: 62 ARGDLASLAVISLGVVVGFPLMTALALRHVTSAHSIVFIGLLPLATAIFGVLRGGERPRP 121 Query: 148 GFWLAALAGSGIVIAFALREGGGSFHPADFALFAAVLTAAMGYAEGGRLAQSMGGQNVIA 207 FW+ + GS IV+ FA R+G + D + AA++ +GYAEG +L++ +GG VI Sbjct: 122 TFWVFSGLGSAIVVGFAARQGFSASPIGDLLMLAAIVACGLGYAEGAKLSRRLGGWQVIC 181 Query: 208 WALVVALPVMLPVSLWLGWQYGVSASAPAWLAFAYVSLFSMFIGFFFWYKGLALGGIARV 267 WALV++LPVM + L SA +WL F YVS+FSM IGF FWY+GLALGGI V Sbjct: 182 WALVLSLPVMTALMLATMPSSLAGPSAASWLGFGYVSVFSMLIGFIFWYRGLALGGIVAV 241 Query: 268 GQVQLLQPFMSLLGAAVIADEALDASNMLFALAVIVVVAIGRRMA 312 GQ+QLLQPF L A+ + E + S + +A++ VA ++ A Sbjct: 242 GQLQLLQPFFGLALASTLLGENVSWSMLAATVAIVACVAGAKKFA 286 >AGc394 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 291 Score = 224 bits (570), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 136/289 (47%), Positives = 182/289 (62%), Gaps = 5/289 (1%) Query: 29 HESRGMWL-GLVGVAVFSLTLPFTRIAVAELNPAFVAFGRAVVAGLCALALLAWIKAPRP 87 ++ WL GL GV +FS +LP TR+AV +P F+ RA +AGL ALALL + RP Sbjct: 2 DKTTSGWLNGLTGVVIFSGSLPATRLAVTGFDPVFLTAARASIAGLLALALLFLFRQKRP 61 Query: 88 TTQQLRGLIITALGVVVGFPLFSSIAMRHVPAAHGAVVVGLLPLATALFGALRFGERPST 147 L LII ++GVVVGFPL +++A+RHV +AH + VGLLPLATA+F +R GERP Sbjct: 62 ARGDLTSLIIVSIGVVVGFPLLTALALRHVTSAHSIIFVGLLPLATAIFAVMRGGERPRP 121 Query: 148 GFWLAALAGSGIVIAFALREGGGSFHPA----DFALFAAVLTAAMGYAEGGRLAQSMGGQ 203 FWL + GS +V F+L + A D + A++ +GYAEG L++ +GG Sbjct: 122 VFWLFSCLGSALVAGFSLSNSFAARIEASLAGDLLMLGAIIVCGLGYAEGAALSRKLGGW 181 Query: 204 NVIAWALVVALPVMLPVSLWLGWQYGVSASAPAWLAFAYVSLFSMFIGFFFWYKGLALGG 263 VI+WALV++LPVMLP++ + G + AW AYVSLFSM IGF FWY+GLALGG Sbjct: 182 QVISWALVLSLPVMLPLAFFTGPETLGGIDPQAWGGLAYVSLFSMLIGFIFWYRGLALGG 241 Query: 264 IARVGQVQLLQPFMSLLGAAVIADEALDASNMLFALAVIVVVAIGRRMA 312 IA VGQ+QLLQPF L AA + E + + + L V++ VA R+ A Sbjct: 242 IAAVGQLQLLQPFFGLALAATLLHEEVSPAMIGVTLVVVLCVAGARKFA 290 >BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 287 Score = 220 bits (561), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 135/285 (47%), Positives = 191/285 (67%), Gaps = 1/285 (0%) Query: 29 HESRGMWL-GLVGVAVFSLTLPFTRIAVAELNPAFVAFGRAVVAGLCALALLAWIKAPRP 87 +++ W+ G +GV +FS +LP TR+AV++ +P F+ RA +AG+ A LL + P Sbjct: 2 NKTTNGWINGFIGVLIFSGSLPATRLAVSDFDPLFLTVCRAAIAGVLAGGLLLIFRQQHP 61 Query: 88 TTQQLRGLIITALGVVVGFPLFSSIAMRHVPAAHGAVVVGLLPLATALFGALRFGERPST 147 + L L++ A GVV+GFPL +++A++HV +AH V +GLLPLATA+FG LR GERP Sbjct: 62 AKRDLISLLVVAFGVVIGFPLLTALALQHVTSAHAIVFIGLLPLATAVFGVLRGGERPRP 121 Query: 148 GFWLAALAGSGIVIAFALREGGGSFHPADFALFAAVLTAAMGYAEGGRLAQSMGGQNVIA 207 FW+ + AGS +V FAL +GGGS D + A+++ +GYAEG +L++ +G VI+ Sbjct: 122 VFWIFSAAGSLLVAGFALIQGGGSSPLGDAYMLASIVVCGLGYAEGAKLSRRLGNWQVIS 181 Query: 208 WALVVALPVMLPVSLWLGWQYGVSASAPAWLAFAYVSLFSMFIGFFFWYKGLALGGIARV 267 WALV++LP+MLP+S + + PA L+ AYVSLFSM IGF FWY+GLA GGIA V Sbjct: 182 WALVLSLPLMLPLSFFFTPDSWSAIGVPALLSLAYVSLFSMLIGFVFWYRGLAQGGIAAV 241 Query: 268 GQVQLLQPFMSLLGAAVIADEALDASNMLFALAVIVVVAIGRRMA 312 GQ+QLLQPF LL A+VI E + + + +AVI+ VA RR A Sbjct: 242 GQLQLLQPFFGLLLASVILHEKVGWALVAVNIAVIMCVAAARRFA 286 >mll1137 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 291 Score = 215 bits (548), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 129/289 (44%), Positives = 178/289 (61%), Gaps = 1/289 (0%) Query: 25 SPARHESRGMWL-GLVGVAVFSLTLPFTRIAVAELNPAFVAFGRAVVAGLCALALLAWIK 83 P ++ W+ G +GV +FS +LP TR+AV + +P FV RA +AGL LA+L + Sbjct: 2 EPGMDKTASGWVNGFIGVLIFSGSLPATRVAVMDFDPTFVTSARAAIAGLLGLAMLLLFR 61 Query: 84 APRPTTQQLRGLIITALGVVVGFPLFSSIAMRHVPAAHGAVVVGLLPLATALFGALRFGE 143 RP L L+I ALGVVVGFPL +++A++H+ +AH + +GLLPLATA+FG LR G+ Sbjct: 62 EKRPDRGDLVSLVIVALGVVVGFPLLTALALKHITSAHSIIFIGLLPLATAIFGVLRGGD 121 Query: 144 RPSTGFWLAALAGSGIVIAFALREGGGSFHPADFALFAAVLTAAMGYAEGGRLAQSMGGQ 203 RP WL + GS +V FAL +G + D + AAV+ +GYAEG L++ +GG Sbjct: 122 RPRPALWLFSCIGSALVAGFALTQGVTASPVGDGLMLAAVIVCGLGYAEGAALSRRLGGW 181 Query: 204 NVIAWALVVALPVMLPVSLWLGWQYGVSASAPAWLAFAYVSLFSMFIGFFFWYKGLALGG 263 VI WAL ++LPVML +S + + AW+ YVSLFSM IGF FWY+GLA GG Sbjct: 182 QVICWALTLSLPVMLVLSFATLPPSFAAVGSHAWIGLGYVSLFSMLIGFVFWYRGLAQGG 241 Query: 264 IARVGQVQLLQPFMSLLGAAVIADEALDASNMLFALAVIVVVAIGRRMA 312 IA VGQ+QLLQPF L AA + E + ++ L V+ V ++ A Sbjct: 242 IAAVGQLQLLQPFFGLALAASLLHEQVSPLMVVVTLGVVACVFGAKKFA 290