BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1559.p (480 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4132 [KE] COG1167 Transcriptional regulators containing a DNA-... 466 e-131 YPO1960 [KE] COG1167 Transcriptional regulators containing a DNA... 399 e-111 STM1598 [KE] COG1167 Transcriptional regulators containing a DNA... 389 e-108 ydcR [KE] COG1167 Transcriptional regulators containing a DNA-bi... 384 e-106 ECs2043 [KE] COG1167 Transcriptional regulators containing a DNA... 382 e-106 >PA4132 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Pae Pseudomonas aeruginosa Length = 471 Score = 466 bits (1198), Expect = e-131, Method: Compositional matrix adjust. Identities = 232/477 (48%), Positives = 319/477 (66%), Gaps = 12/477 (2%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESRGIIESQPQSG 66 Y++FAD++A IR GVL PG+++ SVR AS+ + VS +TV +AY LLESRG+I ++ +SG Sbjct: 4 YEKFADEIAELIRTGVLAPGQKVPSVRHASRTYGVSASTVFQAYYLLESRGLIMARARSG 63 Query: 67 YFVRQQAETIARPTASP---PVQADHPAWQQSTEVDVSRLVLATLKTIQQDGTVPLGSPY 123 YFV Q + RP P P QAD +TEVDVS LV + L +I+ TVP GS + Sbjct: 64 YFVCQH---VQRPLPEPEISPRQAD------ATEVDVSELVFSVLSSIKDPDTVPFGSAF 114 Query: 124 PNPALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPAEIVV 183 P+P LFP RLA+ R SV D+ PG+ L RQIA RY+ GL + E+V+ Sbjct: 115 PSPQLFPLPRLARSMAHAVRDMDPQSVVADMTPGNHGLRRQIALRYMVGGLLLPVEELVI 174 Query: 184 TVGATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPRRGIDVAALE 243 + GA EA+NLCLQ V RPGD +A+E P FYA L +ERL ++A+EIP PR GID+ L Sbjct: 175 SNGALEALNLCLQVVTRPGDLVAIEAPAFYATLQVLERLKLKAVEIPVHPREGIDLEVLA 234 Query: 244 ERLQTQAVAACMVMPNFQNPLGFQMPDSEKERLVRLAAQHQMPIIENAVYSELYYGNAHP 303 + L+ + AC M NFQNP+G M D +K L L A+HQ+P+IE+ VY+ELY+G P Sbjct: 235 DSLERLPIKACWFMSNFQNPMGASMDDEKKRALAELLARHQVPMIEDDVYAELYFGQQAP 294 Query: 304 SSLKNYDRDGLVLHCSSFSKSLTSAHRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIA 363 +K YD++GLV+HCSSFSKSL +R+GW GRY Q+E+LK + +L+ Q AIA Sbjct: 295 KPVKAYDQEGLVMHCSSFSKSLAPGYRVGWVAGGRYAEQIERLKLMTSLSASIPAQAAIA 354 Query: 364 EYLTQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPEGGYVLWVELPPQVDAM 423 +YL GGY+RHLR++R A Q++ M V R+FP T+VS P GGY LW+ELP VD++ Sbjct: 355 DYLQHGGYDRHLRKLRYALETQQNAMLAAVARYFPEQTRVSRPSGGYFLWLELPEAVDSL 414 Query: 424 ELYRRSLALGITVAPGRIFAATNRYSHFIRLNYSYTWSKETEQALKLVGKLVEELAG 480 L++ +LA GI++APG IF+AT R++H RLNY + WS E+A++ +G++ + LAG Sbjct: 415 RLFQLALAQGISLAPGPIFSATRRFAHCARLNYGHPWSARQEKAMETLGRITQSLAG 471 >YPO1960 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Ype Yersinia pestis Length = 473 Score = 399 bits (1025), Expect = e-111, Method: Compositional matrix adjust. Identities = 190/472 (40%), Positives = 299/472 (63%), Gaps = 7/472 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESRGIIESQPQSG 66 Y+Q A Q+ A I+ V + G+++ S+R + +Q +S+ TVV++Y+LLES+G I ++PQSG Sbjct: 4 YEQLAQQIRAQIQSKVWQAGDKLPSLRESCKQSGLSLMTVVQSYQLLESQGWIVARPQSG 63 Query: 67 YFVRQQAETIARPTASPPVQADHPAWQQSTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V + + +P + D +VD++ + L+ + +P GS +P+P Sbjct: 64 YYVASRPTQLPQPQRGNKLHLDE-------QVDINTFIFNVLQAGKDPAIMPFGSAFPDP 116 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPAEIVVTVG 186 +L RL++ +AR S S +LPPG+ L R IA+RY G+ V P EIV+T G Sbjct: 117 SLLLQPRLSRALASVARKISPQSSVTNLPPGNESLRRNIAQRYAACGMNVSPEEIVITAG 176 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPRRGIDVAALEERL 246 A E+++L LQAV +PGD + +E+P FY L AIERL ++A+ I TDP++G+D+ ALE+ + Sbjct: 177 AMESLSLSLQAVTQPGDWVVIESPAFYGALQAIERLRLKAIAITTDPQQGVDLEALEQVI 236 Query: 247 QTQAVAACMVMPNFQNPLGFQMPDSEKERLVRLAAQHQMPIIENAVYSELYYGNAHPSSL 306 + AC +MP+FQNP+G MP S+K+RLV L Q + +IE+ VY ELY+G Sbjct: 237 SQYPIKACWLMPHFQNPMGATMPWSQKQRLVTLLQQKAISLIEDDVYGELYFGAERLLPA 296 Query: 307 KNYDRDGLVLHCSSFSKSLTSAHRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K D+ +LHCSSFSK L R+GW G + +++ L+ ++T++ Q AIA+YL Sbjct: 297 KALDQHRQILHCSSFSKCLAPGFRVGWVAAGEHAQRIQHLQLMSTVSASVPTQLAIADYL 356 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPEGGYVLWVELPPQVDAMELY 426 +QGGY+ HLRR+RR Q+ + V+ FP ++S P GGY LW+EL P +A ELY Sbjct: 357 SQGGYDTHLRRLRRVMEQRMSTLHQAVVEHFPKNIKISHPAGGYFLWLELEPPFNASELY 416 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYTWSKETEQALKLVGKLVEEL 478 RR+L G+++APGR+F +++ H RLN S+ WS+++ +A++++ KL+ +L Sbjct: 417 RRALEQGVSIAPGRMFTTGSQFDHCFRLNASFAWSEQSAKAIRILAKLIGQL 468 >STM1598 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Sty Salmonella typhimurium LT2 Length = 474 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 196/472 (41%), Positives = 291/472 (61%), Gaps = 8/472 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESRGIIESQPQSG 66 Y++ A+Q+ I GV +PG+R+ S+R +S TV AY+LLES+G I ++PQSG Sbjct: 4 YQRLAEQIREQIASGVWQPGDRLPSLREQVASSGMSFMTVGHAYQLLESQGRIIARPQSG 63 Query: 67 YFVRQQAETIARPTASPPVQADHPAWQQSTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V + TA+ ++ + VD++ + L+ + VP S +P+P Sbjct: 64 YYVAPHPVCRSVATAAHVIRDE--------AVDINTYIFEMLQASRDTSVVPFASAFPDP 115 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPAEIVVTVG 186 LFP +L + ++++ A+ SV ++LPPG+ EL IARRY + G+ V P EIV+T G Sbjct: 116 RLFPLPQLNRSLAQVSKTATAMSVIENLPPGNAELRYAIARRYAQQGITVSPDEIVITAG 175 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPRRGIDVAALEERL 246 A EA+NL LQAV PGD + VE P FY L A+ERL ++AL IPTD + GID+ ALE+ L Sbjct: 176 ALEALNLSLQAVTAPGDWVVVENPCFYGALQALERLRLKALSIPTDVKEGIDLMALEQAL 235 Query: 247 QTQAVAACMVMPNFQNPLGFQMPDSEKERLVRLAAQHQMPIIENAVYSELYYGNAHPSSL 306 Q V AC +M N QNPLGF + +K RLV L H + +IE+ VYSELY+G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLSAEKKARLVALLTHHNVTLIEDDVYSELYFGREKPLPA 295 Query: 307 KNYDRDGLVLHCSSFSKSLTSAHRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K +DRD VLHCSSFSK L RIGW G + Q+++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRDDTVLHCSSFSKCLVPGFRIGWVAGGSHARQIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPEGGYVLWVELPPQVDAMELY 426 + Y+ HLRR+RR A+++ +LR PA ++ + GY LW+ELP Q+DA EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQQAWQTLLRHLPAEVKIHHNDSGYFLWLELPEQLDAGELS 415 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYTWSKETEQALKLVGKLVEEL 478 ++L I++APG++F+ + ++ F R N ++ W + EQA+K +G L+ E+ Sbjct: 416 AKALEHLISIAPGKMFSTSGAWTRFFRFNTAWHWGEREEQAVKQLGSLIREM 467 >ydcR [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Eco Escherichia coli K12 Length = 468 Score = 384 bits (985), Expect = e-106, Method: Compositional matrix adjust. Identities = 198/472 (41%), Positives = 290/472 (61%), Gaps = 10/472 (2%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESRGIIESQPQSG 66 Y+Q A+QL I G+ +PG+R+ S+R +S TV AY+LLES+G I ++PQSG Sbjct: 4 YQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSG 63 Query: 67 YFVRQQAETIARPTASP-PVQADHPAWQQSTEVDVSRLVLATLKTIQQDGTVPLGSPYPN 125 Y+V QA I P A PV D VD++ + L+ + VP S +P+ Sbjct: 64 YYVAPQA--IKMPKAPVIPVTRDE-------AVDINTYIFDMLQASRDPSVVPFASAFPD 114 Query: 126 PALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPAEIVVTV 185 P LFP +L + ++++ A+ SV ++LPPG+ EL + IARRY G+ + P EIV+T Sbjct: 115 PRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITA 174 Query: 186 GATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPRRGIDVAALEER 245 GA EA+NL LQAV PGD + VE P FY L A+ERL ++AL + TD + GID+ ALE Sbjct: 175 GALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELA 234 Query: 246 LQTQAVAACMVMPNFQNPLGFQMPDSEKERLVRLAAQHQMPIIENAVYSELYYGNAHPSS 305 LQ V AC +M N QNPLGF + +K +LV L Q+ + +IE+ VYSELY+G P Sbjct: 235 LQEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLP 294 Query: 306 LKNYDRDGLVLHCSSFSKSLTSAHRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEY 365 K +DR VLHCSSFSK L RIGW G++ ++++L+ ++TL+T + Q A+ +Y Sbjct: 295 AKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDY 354 Query: 366 LTQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPEGGYVLWVELPPQVDAMEL 425 L+ Y+ HLRR+RR A+++ +LR+ PA ++ + GY LW+ELP +DA EL Sbjct: 355 LSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGEL 414 Query: 426 YRRSLALGITVAPGRIFAATNRYSHFIRLNYSYTWSKETEQALKLVGKLVEE 477 +L I++APG++F+ +S F R N ++ W + EQA+K +GKL++E Sbjct: 415 SLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWGEREEQAVKQLGKLIQE 466 >ECs2043 [KE] COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Ecs Escherichia coli O157:H7 Length = 468 Score = 382 bits (981), Expect = e-106, Method: Compositional matrix adjust. Identities = 193/471 (40%), Positives = 289/471 (61%), Gaps = 8/471 (1%) Query: 7 YKQFADQLAASIRDGVLRPGERIASVRIASQQHKVSVTTVVRAYELLESRGIIESQPQSG 66 Y+Q A+QL I G+ +PG+R+ S+R +S TV AY+LLES+G I ++PQSG Sbjct: 4 YQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSG 63 Query: 67 YFVRQQAETIARPTASPPVQADHPAWQQSTEVDVSRLVLATLKTIQQDGTVPLGSPYPNP 126 Y+V QA + + P + + VD++ + L+ + VP S +P+P Sbjct: 64 YYVAPQAIKMPKVPVIPVTRDE--------AVDINTYIFDMLQASRDPSVVPFASAFPDP 115 Query: 127 ALFPSHRLAQYAGRIARHASQSSVFDDLPPGHPELLRQIARRYLENGLKVDPAEIVVTVG 186 LFP +L + ++++ A+ SV ++LPPG+ EL + IARRY G+ + P EIV+T G Sbjct: 116 RLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYALQGITISPDEIVITAG 175 Query: 187 ATEAINLCLQAVARPGDTIAVETPTFYAMLHAIERLGMRALEIPTDPRRGIDVAALEERL 246 A EA+NL LQAV PGD + VE P FY L A+ERL ++AL + TD + GID+ ALE L Sbjct: 176 ALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELAL 235 Query: 247 QTQAVAACMVMPNFQNPLGFQMPDSEKERLVRLAAQHQMPIIENAVYSELYYGNAHPSSL 306 Q V AC +M N QNPLGF + +K +LV L Q+ + +IE+ VYSELY+G P Sbjct: 236 QEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPA 295 Query: 307 KNYDRDGLVLHCSSFSKSLTSAHRIGWAMPGRYRAQVEKLKFLNTLATPTAPQRAIAEYL 366 K +DR VLHCSSFSK L RIGW G++ ++++L+ ++TL+T + Q A+ +YL Sbjct: 296 KAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYL 355 Query: 367 TQGGYERHLRRVRRAFAQQRDMMRHFVLRFFPAGTQVSEPEGGYVLWVELPPQVDAMELY 426 + Y+ HLRR+RR A+++ +LR+ PA ++ + GY LW+ELP +DA EL Sbjct: 356 STRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYFLWLELPEPLDAGELS 415 Query: 427 RRSLALGITVAPGRIFAATNRYSHFIRLNYSYTWSKETEQALKLVGKLVEE 477 +L I++APG++F+ +S F R N ++ W + EQA+K +GKL++E Sbjct: 416 LAALTHHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQE 466