BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1552.p (294 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0519 [GER] COG0697 Permeases of the drug/metabolite transport... 49 1e-05 AF0510 [GER] COG0697 Permeases of the drug/metabolite transporte... 45 2e-04 PA1411 [GER] COG0697 Permeases of the drug/metabolite transporte... 41 0.003 STM4400 [GER] COG0697 Permeases of the drug/metabolite transport... 41 0.004 PM1698 [GER] COG0697 Permeases of the drug/metabolite transporte... 40 0.006 >RSc0519 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 301 Score = 49.3 bits (116), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 74/284 (26%), Positives = 129/284 (45%), Gaps = 20/284 (7%) Query: 9 ILVALIWGIQPVISRYGLQQGLTPYDATLLRYLTSGLLVLPYACKRGLIGACGVGWSRGL 68 +++ L WG+Q V + + + P +R + +LVL +A RG G G Sbjct: 21 VVLCLCWGLQQVAIKVAVHD-VGPVMQAGVRSAIASVLVLAFALWRGTRLTLRDGTLPG- 78 Query: 69 VLFILSGPLFS---LVLVAGVNYAPASHGALIHPALTPLFGLAISRFVFGQRERFSLW-G 124 + +G LF L + G+ + AS A+ L + FV G+ R W G Sbjct: 79 --GLAAGTLFGIEFLCIFIGLGHTTASRMAVFLYTAPIFTALGLHAFVPGEHLRPRQWLG 136 Query: 125 MLLLLAGLVLVGLNGLLASGGLKPAG---AWRGDLLFVLSAFMWAWYLVLNRNWKI--AP 179 + + AG+VL A G L PA GD L VL+ +W+ ++ R ++ AP Sbjct: 137 IGVAFAGMVLA-----FADGMLHPAAGPSTSLGDALGVLAGVLWSATTLVVRASRLSEAP 191 Query: 180 LDAVALTQVLSLGCMVLTLPWLGGQTFGKPL-PALLLQSAYHGVLVSIVSVALFNWVVAR 238 L Q+ ++LT+ GQ + L P L AY VL++ S ++ W++ R Sbjct: 192 AAKTLLYQLAVSAVLLLTMAAGTGQAWTANLTPTALASLAYQSVLIAFASYLVWFWLLRR 251 Query: 239 -LGVKALMLNALSPLFGVIASAGVLREPLSVSMMVGAVVIVGGL 281 L + + + L+P+FGV + +L +P+ + + A +++ G+ Sbjct: 252 YLASRLSVFSFLTPMFGVAFAVLLLHDPVGLRFALAAALVLSGI 295 >AF0510 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Afu Archaeoglobus fulgidus Length = 289 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 68/281 (24%), Positives = 118/281 (41%), Gaps = 20/281 (7%) Query: 10 LVALIWGIQPVISRYGLQQGLTPYDATLLRYLTSGLLVLPYAC-KRGLIGACGVGWSRGL 68 L LIW + + GL++ L P++ R+L + L++ + KRGL G W Sbjct: 11 LTMLIWAGSFIFIKIGLKE-LDPFNLAFYRFLLASPLLMAWVFWKRGLAKPSGSEWLHLS 69 Query: 69 VLFILSGPLFSLVLVAGVNYAPASHGALI---HPALTPLFGLAISRFVFGQRERFSLWGM 125 VL + L + Y A++ +++ L+GL V G+ L G+ Sbjct: 70 VLALSGVTLLYAFQFLALKYTTATNASILINTSAVFVALWGL-----VKGEANPRKLAGV 124 Query: 126 LLLLAGLVLVGLNGLLASGGLKPAGAWRGDLLFVLSAFMWAWYLVLNRNWKIAPLDAVAL 185 L AG+VL+ G L K GD+L ++ F+WA Y VL + D L Sbjct: 125 FLSFAGVVLIVSKGTLEFFSSKTI---FGDVLMIVDGFLWAVYTVLGSK-MLLKYDHETL 180 Query: 186 T-QVLSLGCMVLTLPWLGGQTFGKPL---PALLLQSAYHGVLVSIVSVALFNWVVARLGV 241 T +LG + L +P+ F P+ P + Y +L S+ + ++ + + Sbjct: 181 TAYAFALGTIFL-IPFALMSGFANPVTFNPETVAALLYLSILCSVFAYVVWYYALTNADS 239 Query: 242 KALMLNA-LSPLFGVIASAGVLREPLSVSMMVGAVVIVGGL 281 ++ + L PLF I + L E +G ++ + G+ Sbjct: 240 TSVAVYVYLVPLFTAIFAFYALNEKPDFFTAIGGIITIAGV 280 >PA1411 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 303 Score = 41.2 bits (95), Expect = 0.003, Method: Compositional matrix adjust. Identities = 74/287 (25%), Positives = 124/287 (43%), Gaps = 26/287 (9%) Query: 9 ILVALIWGIQPVISRYGLQQGLTPYDATLLRYLTSGLLVLPYACKRG-----LIGACGVG 63 +L+ +IWGIQ V ++ + P +R + LV C RG G G G Sbjct: 14 LLLCVIWGIQQVTIKWAATD-IAPVMQAAIRSGIAAALVGLLMCWRGGWEGLRQGTLGAG 72 Query: 64 WSRGLVLFILSGPLFSL---VLVAGVNYAPASH-GALIHPALTPLF-GLAISRFVFGQRE 118 +L+G LF+L + G+ Y ASH ++ A P+F L + + +R Sbjct: 73 --------LLTGTLFALEFLFIALGLQYTTASHMSVFLYTA--PIFSALGLHFLLPSERL 122 Query: 119 RFSLWGMLLLLAGLVLVGLNGLLASGGLKPAGAWRGDLLFVLSAFMWAWYLVLNRNWKIA 178 R W + + G + V G L+ + GD +L+ W V R +++ Sbjct: 123 RPLQWLGVAVCFGGIAVAFGGGLSWAEMD-GRMLLGDAFGLLAGMSWGATTVAVRGTRLS 181 Query: 179 PLD-AVALTQVLSLGCMVLTLPWLGGQTFGKP--LPALLLQSAYHGVLVSIVSVALFNWV 235 ++ L L + C L L L FG+ P + GV+VS S + W+ Sbjct: 182 EAPPSLTLFYQLFVACAGLLLIALFSGQFGEVRWTPVSTASVLFQGVVVSFASYFCWFWL 241 Query: 236 VAR-LGVKALMLNALSPLFGVIASAGVLREPLSVSMMVGAVVIVGGL 281 + R L + + ++PLFGV +L EPLS++ + GA +++ G+ Sbjct: 242 LRRYLANNLAIFSFMTPLFGVTFGVLLLGEPLSLNFVAGAALVLAGI 288 >STM4400 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 321 Score = 40.8 bits (94), Expect = 0.004, Method: Compositional matrix adjust. Identities = 43/148 (29%), Positives = 63/148 (42%), Gaps = 15/148 (10%) Query: 39 RYLTSGLLVLPYAC--KRGLIGACGVGWSRGLVLFILSGPLFSLVLVAGVNYAPASHGAL 96 RYL GL+ LP A + L WS L L ++ ++ L + + A + Sbjct: 37 RYLALGLIALPIAWLGRTRLRQLTRKDWSTALSLTLMGNVIYYACLASAIQRTGAPVSTM 96 Query: 97 IH---PALTPLFGLAISRFVFGQRERFSLWGML---LLLAGLVLVGLNGLLASGGLKPAG 150 I P + PLF + ++ QR+ W L L L G L+ +N S GL Sbjct: 97 IIGTLPVVIPLF----ANVLYSQRDGRLSWRRLAPALALIGFGLLCVNIAELSQGLSDVS 152 Query: 151 AWR---GDLLFVLSAFMWAWYLVLNRNW 175 WR G +L ++S WAWY + N W Sbjct: 153 GWRYGSGIVLALISVACWAWYALRNARW 180 >PM1698 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pmu Pasteurella multocida Length = 301 Score = 40.0 bits (92), Expect = 0.006, Method: Compositional matrix adjust. Identities = 65/219 (29%), Positives = 97/219 (44%), Gaps = 23/219 (10%) Query: 77 LFSLVLVAGVNYAPASHGALIHPALTPLFGLAISRFVFGQRERFS-LWGMLLLLAGLVLV 135 +F + L G+ S A I+ A+ P+F L ++R VFG F+ L G L V Sbjct: 82 IFPVFLYQGLQ-TTTSLNASIYLAVVPIFVLFLNRLVFGDPINFTGLTGAL-----FSFV 135 Query: 136 GLNGLLASGGLK---PAGAWRGDLLFVLSAFMWAWYLVLNRNWKIAPLDAVALTQVLSLG 192 G+ LL+ G ++ +GDL + SA W+ Y L R K A L L L Sbjct: 136 GVLWLLSRGDIQRLTQLEVNQGDLWALGSALSWSIYCCLIR-LKPAQLPNTVLLTTLVCM 194 Query: 193 CMVLTLPWLGGQTFGKPLPALL--LQSAYHGVLV------SIVSVALFNWVVARLGVK-- 242 M+L P Q P PA L + ++ SI+S +N+ ++ +G Sbjct: 195 AMLLFTPLFIWQYQQLP-PAFFSTLTPTQYSIITYLIIGPSILSYGFWNYGISLVGADKG 253 Query: 243 ALMLNALSPLFGVIASAGVLREPLSVSMMVGAVVIVGGL 281 A NA +PLF + VL E L+ M+ A +I+ GL Sbjct: 254 AAFTNA-TPLFAALLGVLVLNEALAFYHMISAGLIITGL 291