BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1518.p (253 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0259 [QR] COG0500 SAM-dependent methyltransferases Sty Salmon... 261 1e-69 Z0233 [QR] COG0500 SAM-dependent methyltransferases EcZ Escheric... 246 3e-65 ECs0206 [QR] COG0500 SAM-dependent methyltransferases Ecs Escher... 246 3e-65 yafE [QR] COG0500 SAM-dependent methyltransferases Eco Escherich... 192 5e-49 PA3119 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudom... 191 2e-48 >STM0259 [QR] COG0500 SAM-dependent methyltransferases Sty Salmonella typhimurium LT2 Length = 256 Score = 261 bits (666), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 137/251 (54%), Positives = 163/251 (64%) Query: 2 RSHQQVVSQQFGSTAAAYLTSAVHAQGADLQELAQIASTMSGARALDLGCGGGHASFAVA 61 SH V +QFGS A AYL SAVHA G DL LAQ S S A LD+GCG GHASF A Sbjct: 4 HSHHDNVEKQFGSQANAYLHSAVHAAGRDLARLAQRLSDFSHASVLDMGCGAGHASFVAA 63 Query: 62 PVVEKVIAYDLSAEMLEVVSRAAQERGLDNLAVRQGSADRLEFPDASFELVCTRFSAHHW 121 V+AYDLSA MLEVV+ AA+ER L N+ +RQG A++L F DASFE+V +R+SAHHW Sbjct: 64 QHANSVVAYDLSASMLEVVAGAAEERHLSNITLRQGYAEKLPFEDASFEVVISRYSAHHW 123 Query: 122 RHLPQALSEVFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKL 181 + QAL EV RVLKPGG I++D +P + D ++Q +E LRDTSHVRN S W + Sbjct: 124 HDVGQALREVNRVLKPGGVLIIMDVMSPGHPVRDIWLQTVEALRDTSHVRNYSSGEWLAM 183 Query: 182 VRAAGFTIASDKTWKLRLEFASWVARMRTPPDQVAAIRALWRAAPQEVKQYFALEADDSF 241 V A + T +L LEF SWV RMRTP V AIR +AP EVK+YF L+ D SF Sbjct: 184 VNNAMLVTNTVITDRLSLEFRSWVTRMRTPAPLVEAIRLYQASAPVEVKRYFELQDDGSF 243 Query: 242 SIDVAMLELRK 252 S D MLE K Sbjct: 244 SSDTIMLEAHK 254 >Z0233 [QR] COG0500 SAM-dependent methyltransferases EcZ Escherichia coli O157:H7 EDL933 Length = 256 Score = 246 bits (629), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 125/251 (49%), Positives = 165/251 (65%) Query: 2 RSHQQVVSQQFGSTAAAYLTSAVHAQGADLQELAQIASTMSGARALDLGCGGGHASFAVA 61 +SH V +QF S A+ YLTS VHA G DLQ LA + A LD+GCG GHASF A Sbjct: 4 QSHHDHVEKQFSSQASEYLTSTVHASGRDLQLLAVCLADYPDASVLDMGCGAGHASFVAA 63 Query: 62 PVVEKVIAYDLSAEMLEVVSRAAQERGLDNLAVRQGSADRLEFPDASFELVCTRFSAHHW 121 V V+AYDLSA+ML+VV++AA+ R L N+ RQG A+ L F D +F++V +R+SAHHW Sbjct: 64 QNVSTVVAYDLSAQMLDVVAQAAEVRQLKNITTRQGYAESLPFADNAFDIVISRYSAHHW 123 Query: 122 RHLPQALSEVFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKL 181 + AL EV R+LKPGGR IV+D +P + D ++Q +E L DTSHVRN + W +L Sbjct: 124 HDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQTVEALCDTSHVRNYASGEWLRL 183 Query: 182 VRAAGFTIASDKTWKLRLEFASWVARMRTPPDQVAAIRALWRAAPQEVKQYFALEADDSF 241 + A + + T KL LEF+SWVARMRTP V AIR ++A EV+ YFAL+ D SF Sbjct: 184 INEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEVRTYFALQNDGSF 243 Query: 242 SIDVAMLELRK 252 + D+ M++ K Sbjct: 244 TSDIIMVDAHK 254 >ECs0206 [QR] COG0500 SAM-dependent methyltransferases Ecs Escherichia coli O157:H7 Length = 256 Score = 246 bits (629), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 125/251 (49%), Positives = 165/251 (65%) Query: 2 RSHQQVVSQQFGSTAAAYLTSAVHAQGADLQELAQIASTMSGARALDLGCGGGHASFAVA 61 +SH V +QF S A+ YLTS VHA G DLQ LA + A LD+GCG GHASF A Sbjct: 4 QSHHDHVEKQFSSQASEYLTSTVHASGRDLQLLAVCLADYPDASVLDMGCGAGHASFVAA 63 Query: 62 PVVEKVIAYDLSAEMLEVVSRAAQERGLDNLAVRQGSADRLEFPDASFELVCTRFSAHHW 121 V V+AYDLSA+ML+VV++AA+ R L N+ RQG A+ L F D +F++V +R+SAHHW Sbjct: 64 QNVSTVVAYDLSAQMLDVVAQAAEVRQLKNITTRQGYAESLPFADNAFDIVISRYSAHHW 123 Query: 122 RHLPQALSEVFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKL 181 + AL EV R+LKPGGR IV+D +P + D ++Q +E L DTSHVRN + W +L Sbjct: 124 HDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQTVEALCDTSHVRNYASGEWLRL 183 Query: 182 VRAAGFTIASDKTWKLRLEFASWVARMRTPPDQVAAIRALWRAAPQEVKQYFALEADDSF 241 + A + + T KL LEF+SWVARMRTP V AIR ++A EV+ YFAL+ D SF Sbjct: 184 INEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEVRTYFALQNDGSF 243 Query: 242 SIDVAMLELRK 252 + D+ M++ K Sbjct: 244 TSDIIMVDAHK 254 >yafE [QR] COG0500 SAM-dependent methyltransferases Eco Escherichia coli K12 Length = 207 Score = 192 bits (488), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 97/203 (47%), Positives = 131/203 (64%) Query: 50 GCGGGHASFAVAPVVEKVIAYDLSAEMLEVVSRAAQERGLDNLAVRQGSADRLEFPDASF 109 G G +F A V V+AYDLSA ML+VV++AA+ R L N+ RQG A+ L F D +F Sbjct: 3 GLPQGRPTFGAAQNVSAVVAYDLSAHMLDVVAQAAEARQLKNITTRQGYAESLPFADNAF 62 Query: 110 ELVCTRFSAHHWRHLPQALSEVFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSH 169 ++V +R+SAHHW + AL EV R+LKPGGR IV+D +P + D ++Q +E LRDTSH Sbjct: 63 DIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWLQTVEALRDTSH 122 Query: 170 VRNVSLNSWRKLVRAAGFTIASDKTWKLRLEFASWVARMRTPPDQVAAIRALWRAAPQEV 229 VRN + W L+ A + + T KL LEF+SWVARMRTP V AIR ++A EV Sbjct: 123 VRNYASGEWLTLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEV 182 Query: 230 KQYFALEADDSFSIDVAMLELRK 252 + YFAL+ D F+ D+ M++ K Sbjct: 183 RTYFALQNDGFFTSDIIMVDAHK 205 >PA3119 [QR] COG0500 SAM-dependent methyltransferases Pae Pseudomonas aeruginosa Length = 187 Score = 191 bits (484), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 97/186 (52%), Positives = 124/186 (66%) Query: 67 VIAYDLSAEMLEVVSRAAQERGLDNLAVRQGSADRLEFPDASFELVCTRFSAHHWRHLPQ 126 ++AYDLSAEML VV+++A ERG+ N+ QG A+ L F D F+ V +R+S HHWR + Sbjct: 1 MVAYDLSAEMLAVVAQSAAERGMANIRTEQGKAESLPFADGEFDFVFSRYSTHHWRDVGL 60 Query: 127 ALSEVFRVLKPGGRFIVIDTAAPADVLADTYVQAIELLRDTSHVRNVSLNSWRKLVRAAG 186 AL EV RVLKPGG I +D AAP L DT++Q +ELLRDTSHVRN S W +L AG Sbjct: 61 ALREVRRVLKPGGVAIFVDVAAPGQALPDTFLQTVELLRDTSHVRNYSPAEWARLSGEAG 120 Query: 187 FTIASDKTWKLRLEFASWVARMRTPPDQVAAIRALWRAAPQEVKQYFALEADDSFSIDVA 246 + + +LRLEF SWV RMRTP AIR+L A +EV++YF + D SFS DV Sbjct: 121 LLVTGSRRQRLRLEFQSWVERMRTPEVFRQAIRSLQLAVGEEVREYFEIADDGSFSTDVL 180 Query: 247 MLELRK 252 +L LR+ Sbjct: 181 VLWLRR 186