BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1516.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1607 [GER] COG0697 Permeases of the drug/metabolite transport... 319 5e-87 PA3358 [GER] COG0697 Permeases of the drug/metabolite transporte... 202 6e-52 SMb20885 [GER] COG0697 Permeases of the drug/metabolite transpor... 201 2e-51 AGc4246 [GER] COG0697 Permeases of the drug/metabolite transport... 161 2e-39 mlr3480 [GER] COG0697 Permeases of the drug/metabolite transport... 158 1e-38 >RSc1607 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 307 Score = 319 bits (817), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 178/292 (60%), Positives = 209/292 (71%), Gaps = 16/292 (5%) Query: 19 VPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLLVLLPLVLLFRAPWPHG------ 72 +P LFVLIWSTGF+VAKFG+PYA P+TFL LRF GVL+ LLPLV + R P P Sbjct: 21 MPWLFVLIWSTGFVVAKFGMPYAEPITFLFLRFVGVLVCLLPLVWVARVPLPRRAGADAD 80 Query: 73 -----RIRHVALAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTAFAAPLLGESV 127 I H+A+AGVL+Q GYL GVW AIK+GMPAG+SALIVG+QPILTA + GE V Sbjct: 81 AVDWRTIGHLAVAGVLMQWGYLGGVWEAIKLGMPAGMSALIVGMQPILTALYVSMRGERV 140 Query: 128 RGRQWVGLALGLCGVGLVVANKISLIGLSTASIALCVFALLCITAGTLYQKRYCAHFDLR 187 RQW+GL G+ GVGLVVANK+ L G++ ++ CV ALL ITAGTLYQKR+C FDLR Sbjct: 141 SPRQWLGLLFGIAGVGLVVANKLHLAGVNVTTLGFCVGALLSITAGTLYQKRFCPVFDLR 200 Query: 188 TGTVIQFMASIVVVLPFAVALEGFDWHVSNVHWTPQFIGALLWSVLALSIGAIFLLFALI 247 G IQF AS ++ LPF A E V WT IGAL+WSVLALSIGAI LLF LI Sbjct: 201 MGACIQFGASALLCLPFMFAFE-----TRAVQWTGPMIGALVWSVLALSIGAISLLFMLI 255 Query: 248 RRSAATSVTSLLYLTPPTTAVMAWLIFGEAFSLIGALGMLLGVIGVAFVVRK 299 R+ AAT VTSLLYLTPPTTA MAW +FGE F + ALGM++ GVA V+R+ Sbjct: 256 RQGAATKVTSLLYLTPPTTAAMAWALFGERFPPLAALGMVIAACGVALVIRR 307 >PA3358 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 292 Score = 202 bits (515), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 144/291 (49%), Positives = 182/291 (62%), Gaps = 11/291 (3%) Query: 10 RSRQFLMRLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLLVLLPLVLLFRAPW 69 R+ +L +PLLFVL+WSTGF+ AKFGLPYA P TFL +R +L LL APW Sbjct: 2 RTPAWLGSGMPLLFVLLWSTGFLGAKFGLPYAEPFTFLAIRLLLAAALLAAFALLSGAPW 61 Query: 70 PHGRIR---HVALAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTA-FAAPLLGE 125 P G R HVA+AG+L+ YL GV+ AI+ GM AGL++L+VGLQP+ TA A LGE Sbjct: 62 P-GSARLAGHVAVAGLLVHGLYLGGVFLAIEHGMSAGLTSLLVGLQPLATAALAGIWLGE 120 Query: 126 SVRGRQWVGLALGLCGVGLVVANKISLIGLSTASIALCVFALLCITAGTLYQKRYCAHFD 185 V RQW+GLALGL GV LVV +I G + A + AL IT GTLYQKR+C D Sbjct: 121 QVSRRQWLGLALGLAGVALVVLGRIH-GGADGLAWAAVLVALAAITCGTLYQKRFCGGMD 179 Query: 186 LRTGTVIQFMASIVVVLPFAVALEGFDWHVSNVHWTPQFIGALLWSVLALSIGAIFLLFA 245 LRTG V+Q++AS ++ A+ E V W+ F+ L W VL LS GA+ LL+ Sbjct: 180 LRTGGVVQYLASGALLGLAALLFE-----SREVQWSTPFVLTLGWLVLGLSFGAVGLLYT 234 Query: 246 LIRRSAATSVTSLLYLTPPTTAVMAWLIFGEAFSLIGALGMLLGVIGVAFV 296 LIR AA+ V SL YL PP TA+ +WL+F E + GMLL ++GVA V Sbjct: 235 LIRHGAASKVASLFYLVPPVTALASWLLFDERLAPAAIGGMLLVMLGVALV 285 Score = 30.0 bits (66), Expect = 6.8, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 4/67 (5%) Query: 232 VLALSIGAIFLLFALIRRSAATSVTSLLY-LTPPTTAVMAWLIFGEAFSLIGALGMLLGV 290 V L +G +FL I + +TSLL L P TA +A + GE S LG+ LG+ Sbjct: 78 VHGLYLGGVFLA---IEHGMSAGLTSLLVGLQPLATAALAGIWLGEQVSRRQWLGLALGL 134 Query: 291 IGVAFVV 297 GVA VV Sbjct: 135 AGVALVV 141 >SMb20885 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 306 Score = 201 bits (511), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 124/294 (42%), Positives = 172/294 (58%), Gaps = 13/294 (4%) Query: 14 FLMRLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLLVLLPLVLLFRAPWPHGR 73 L RL P +FVL+WSTG++VAK+ +A PL FL LR++ +L+ + LL A WP Sbjct: 1 MLARLAPAIFVLLWSTGWVVAKYAAIFADPLIFLALRYSFAILLFIGFCLLSGARWPRSA 60 Query: 74 --IRHVALAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTAFAAP-LLGESVRGR 130 I H ++G+ L YL VW AI G+PA +S +I GLQP++TA AP L+GE + G+ Sbjct: 61 TAIGHAVVSGIFLHGLYLGAVWWAIGQGVPAAISGIIAGLQPLMTAAVAPWLIGEKLAGQ 120 Query: 131 QWVGLALGLCGVGLVVANKISLIGLSTASI-----ALCVFALLCITAGTLYQKRYCAHFD 185 Q +GL LG CG+ L VA K+ I + I A+ V + +T GTLYQKRY D Sbjct: 121 QKLGLILGFCGIALAVAPKMLTIDATATPIHLLPLAVNVLGMAAVTYGTLYQKRYLQTGD 180 Query: 186 LRTGTVIQFMASIVVVLPFAVALEGFDWHVSNVHWTPQFIGALLWSVLALSIGAIFLLFA 245 +R+ +Q++ +++V +P A+ LE V W + + AL WSVL LS+GAI LL Sbjct: 181 IRSIAALQYVGALLVTIPLALMLEDL-----RVTWNIELVAALAWSVLGLSMGAIALLLY 235 Query: 246 LIRRSAATSVTSLLYLTPPTTAVMAWLIFGEAFSLIGALGMLLGVIGVAFVVRK 299 LIRR + SL+YL PP A A L FGEA + +G ++ V GV RK Sbjct: 236 LIRRGQVSRAASLIYLVPPLAAGEAALFFGEALTWPMIIGTVIAVTGVYLTNRK 289 >AGc4246 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 354 Score = 161 bits (407), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 114/298 (38%), Positives = 165/298 (55%), Gaps = 13/298 (4%) Query: 10 RSRQFLMRLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRFTGVLLVLLPLVLLFRAPW 69 R L RL P +FV +WSTG++ AK+ + Y PLTFL LR+ L+L + W Sbjct: 54 RCSMSLDRLAPAIFVFLWSTGWVTAKYAVYYTGPLTFLCLRYLLAGLLLWAICRFSGISW 113 Query: 70 PHGR--IRHVALAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTAFAAP-LLGES 126 P R + L+GV L YL +W AI G+PA + +I GLQP++TA AA ++GE Sbjct: 114 PKQRADVLRAILSGVFLHGIYLGMIWWAIGQGVPAAIGGIIAGLQPLMTAVAARFMIGER 173 Query: 127 VRGRQWVGLALGLCGVGLVVANKI---SLIGLSTA--SIALCVFALLCITAGTLYQKRYC 181 + Q GL LG G+ + V K+ +G+S ++A+ V ++ +T GTLYQK+Y Sbjct: 174 ISPLQRAGLLLGFAGIAIAVLPKVMATGALGMSVPLYAVAVNVLGMVSVTYGTLYQKKYV 233 Query: 182 AHFDLRTGTVIQFMASIVVVLPFAVALEGFDWHVSNVHWTPQFIGALLWSVLALSIGAIF 241 ++ +Q++ +++V +PFA+ LE D HV W+ L WSV A+SIGA+ Sbjct: 234 HGGNIMAVATLQYVGALLVTVPFALLLE--DGHVD---WSLGLAATLGWSVGAISIGAVA 288 Query: 242 LLFALIRRSAATSVTSLLYLTPPTTAVMAWLIFGEAFSLIGALGMLLGVIGVAFVVRK 299 LL LIRR + SL+YL PP AV A ++FGE + G +L V GV RK Sbjct: 289 LLLYLIRRGQVSRAASLIYLVPPLAAVEAAVLFGETLTPAMIAGTVLAVTGVYLANRK 346 >mlr3480 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 303 Score = 158 bits (400), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 113/293 (38%), Positives = 172/293 (58%), Gaps = 13/293 (4%) Query: 13 QFLMRLVPLLFVLIWSTGFIVAKFGLPYAPPLTFLLLRF--TGVLL-VLLPLVLLFRAPW 69 Q + R +P FV++W+TGFI A++ +P+A P TFL RF +LL VL+P++ RA Sbjct: 2 QSIKRFIPATFVVLWATGFIGARYAMPWAEPFTFLAARFVIAAILLAVLMPVLGSKRAT- 60 Query: 70 PHGRIRHVALAGVLLQAGYLAGVWCAIKIGMPAGLSALIVGLQPILTA-FAAPLLGESVR 128 H AGVL+ YL V+ AI GMPAG SALIVGLQP++TA A LGE++ Sbjct: 61 -RKEALHATGAGVLMHGVYLGAVFWAIHRGMPAGFSALIVGLQPLITAVLAGKFLGEAIL 119 Query: 129 GRQWVGLALGLCGVGLVVANKISLIG--LSTASIALCVFALLCITAGTLYQKRYCAHFDL 186 R W+GL +GL G+ +V+ K+ +G ++ A++ + ++L ++AGT++QKR+ + DL Sbjct: 120 PRHWLGLGIGLIGIVIVLWPKLGALGGGVTAATLTASLVSVLGMSAGTIWQKRFASGGDL 179 Query: 187 RTGTVIQFMASIVVVLPFAVALEGFDWHVSNVHWTPQFIGALLWSVLALSIGAIFLLFAL 246 T+ Q++ +++ A+A E V + I A+ W VL LS+GAIFLL + Sbjct: 180 VAATMWQYVGGASLMILAALAFE-----THTVIINGELIFAMAWLVLVLSLGAIFLLMVM 234 Query: 247 IRRSAATSVTSLLYLTPPTTAVMAWLIFGEAFSLIGALGMLLGVIGVAFVVRK 299 IR + V SL YL P TA++AW +F E + + +GM + GV + Sbjct: 235 IRDGEMSKVASLFYLVPAVTAIIAWALFDEQLNALQIVGMAITTFGVGLATAR 287