BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1478.p (289 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1873 [F] COG0788 Formyltetrahydrofolate hydrolase Rso Ralston... 414 e-116 XF1831 [F] COG0788 Formyltetrahydrofolate hydrolase Xfa Xylella ... 353 2e-97 AGl1261 [F] COG0788 Formyltetrahydrofolate hydrolase Atu Agrobac... 315 1e-85 BMEII0387 [F] COG0788 Formyltetrahydrofolate hydrolase Bme Bruce... 310 2e-84 AGc4474 [F] COG0788 Formyltetrahydrofolate hydrolase Atu Agrobac... 309 6e-84 >RSc1873 [F] COG0788 Formyltetrahydrofolate hydrolase Rso Ralstonia solanacearum Length = 288 Score = 414 bits (1065), Expect = e-116, Method: Compositional matrix adjust. Identities = 199/289 (68%), Positives = 229/289 (79%), Gaps = 1/289 (0%) Query: 1 MAHPEYILTLSCLDQRGIVHRVSGFLADHGCNIIDSAQFGDAQSKLFFMRVHFASEDGAM 60 M+H +ILTLSC DQ GIVH VSG L + GCNI+DS QFGD + FFMRVHF + + Sbjct: 1 MSHSGFILTLSCPDQPGIVHAVSGLLFEQGCNILDSDQFGDEFTGRFFMRVHFVPQGQPL 60 Query: 61 SDAALRADFGVLGDSLQMNWQLHDAGKKPRVMLMVSKIGHCLNDLLFRYKSGLLPVEIPA 120 ALR F +G+ M W + DA KPRVM++VSKIGHCLNDLLFR ++G LP+EI A Sbjct: 61 DLQALRERFAPIGERFSMQWGMFDAAVKPRVMILVSKIGHCLNDLLFRARAGQLPIEIAA 120 Query: 121 IVSNHTDFYQLAASYNIPFHHLPLATGSSAQVKRAQEQRIMEIVEANQIDLVVLARYMQI 180 IVSNH DFYQLAASY++PF HLPL G+ AQ K QE RI EI+E +IDLVVLARYMQI Sbjct: 121 IVSNHRDFYQLAASYDVPFLHLPLLKGTDAQ-KAQQEARIREIIEEQRIDLVVLARYMQI 179 Query: 181 LSPEMCEALRGRAINIHHSFLPSFKGAKPYYQAHDRGVKLIGATAHFVTGDLDEGPIIEQ 240 LS ++C L GRAINIHHSFLPSFKGAKPYYQAH+RGVKLIGATAH+VT +LDEGPIIEQ Sbjct: 180 LSDDLCRQLEGRAINIHHSFLPSFKGAKPYYQAHERGVKLIGATAHYVTAELDEGPIIEQ 239 Query: 241 GVERVDHSMGPDTLTAIGRDIECVVLARAVKWFTEHRILLNGHKTVIFN 289 +ERVDHSM P+ LTA+GRD+ECV LARAVKW EHRILLNGHKTV+F Sbjct: 240 EIERVDHSMDPEQLTAVGRDVECVALARAVKWHAEHRILLNGHKTVVFK 288 >XF1831 [F] COG0788 Formyltetrahydrofolate hydrolase Xfa Xylella fastidiosa 9a5c Length = 283 Score = 353 bits (907), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 177/284 (62%), Positives = 212/284 (74%), Gaps = 5/284 (1%) Query: 5 EYILTLSCLDQRGIVHRVSGFLADHGCNIIDSAQFGDAQSKLFFMRVHFASEDGAMSDAA 64 +YILTLSC D G+V+R+SG L GCNI+D+ QFGD +S LFF+RVHF D + S A Sbjct: 4 DYILTLSCPDCTGLVYRISGELFRAGCNILDAQQFGDKESHLFFLRVHFDVADSS-SLAQ 62 Query: 65 LRADFGVLGDSLQMNWQLHDAGKKPRVMLMVSKIGHCLNDLLFRYKSGLLPVEIPAIVSN 124 L+ +L ++ M WQLHDA + R+++MVSK GHCLNDLLFR S L +I +VSN Sbjct: 63 LQDQINILAEAYAMQWQLHDARRGSRLLVMVSKQGHCLNDLLFRIHSRQLQAKIVTVVSN 122 Query: 125 HTDFYQLAASYNIPFHHLPLATGSSAQVKRAQEQRIMEIVEANQIDLVVLARYMQILSPE 184 H DF L ASY +PF HLP+ +A + QE RI+++VE QIDLV+LARYMQILSP Sbjct: 123 HNDFAPLTASYGVPFQHLPV----NADNRTEQEARILQMVEREQIDLVILARYMQILSPA 178 Query: 185 MCEALRGRAINIHHSFLPSFKGAKPYYQAHDRGVKLIGATAHFVTGDLDEGPIIEQGVER 244 +CEAL GRAINIHHSFLPSFKGA+PY+QAH RGVK+IGATAH+VT DLDEGPIIEQ V R Sbjct: 179 LCEALLGRAINIHHSFLPSFKGAQPYHQAHARGVKIIGATAHYVTHDLDEGPIIEQDVAR 238 Query: 245 VDHSMGPDTLTAIGRDIECVVLARAVKWFTEHRILLNGHKTVIF 288 VDHSM L IG DIE +VLARAV EHRILLNGH+TV+F Sbjct: 239 VDHSMTAHDLVRIGSDIESLVLARAVSRHIEHRILLNGHRTVVF 282 >AGl1261 [F] COG0788 Formyltetrahydrofolate hydrolase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 300 Score = 315 bits (806), Expect = 1e-85, Method: Compositional matrix adjust. Identities = 149/283 (52%), Positives = 200/283 (70%), Gaps = 5/283 (1%) Query: 6 YILTLSCLDQRGIVHRVSGFLADHGCNIIDSAQFGDAQSKLFFMRVHFASEDGAMSDAAL 65 ++LT++C RGIV +SG LA+ GCNI+DS+QF D + FFMRV F SE+GA +A L Sbjct: 10 FVLTVTCKSTRGIVAALSGLLAEKGCNIVDSSQFDDLGTGRFFMRVGFISEEGATREA-L 68 Query: 66 RADFGVLGDSLQMNWQLHDAGKKPRVMLMVSKIGHCLNDLLFRYKSGLLPVEIPAIVSNH 125 A + + M LHD ++ +V+LMVS+ GHCLNDLL+R++ G LP++I +VSNH Sbjct: 69 MAGLAPISKTFGMEVALHDQAERMKVLLMVSRFGHCLNDLLYRWRIGALPIDIVGVVSNH 128 Query: 126 TDFYQLAASYNIPFHHLPLATGSSAQVKRAQEQRIMEIVEANQIDLVVLARYMQILSPEM 185 D+ ++ +++IPFHH+P+ + Q E RIMEI E+ +LVVLARYMQ+LS M Sbjct: 129 FDYQKVVVNHDIPFHHIPVTKENKPQA----EARIMEIAESTGTELVVLARYMQVLSDRM 184 Query: 186 CEALRGRAINIHHSFLPSFKGAKPYYQAHDRGVKLIGATAHFVTGDLDEGPIIEQGVERV 245 CEA+ G+ INIHHSFLPSFKGA PY QA+ RGVKLIGATAH+VT DLDEGPIIEQ + R+ Sbjct: 185 CEAMSGKIINIHHSFLPSFKGANPYKQAYQRGVKLIGATAHYVTADLDEGPIIEQDIVRI 244 Query: 246 DHSMGPDTLTAIGRDIECVVLARAVKWFTEHRILLNGHKTVIF 288 H+ + ++GRD+E VLARA+ R+ LNG +TV+F Sbjct: 245 THAQSAEDYVSLGRDVEAQVLARAIHAHIHRRVFLNGSRTVVF 287 >BMEII0387 [F] COG0788 Formyltetrahydrofolate hydrolase Bme Brucella melitensis Length = 294 Score = 310 bits (794), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 149/284 (52%), Positives = 197/284 (69%), Gaps = 5/284 (1%) Query: 5 EYILTLSCLDQRGIVHRVSGFLADHGCNIIDSAQFGDAQSKLFFMRVHFASEDGAMSDAA 64 ++LT++C RGIV +SG+LA GCNIIDSAQF D + FFMRV F SE+G + D Sbjct: 3 NFVLTVTCKSTRGIVAAISGYLAGKGCNIIDSAQFDDLDTGRFFMRVSFISEEGVLLDE- 61 Query: 65 LRADFGVLGDSLQMNWQLHDAGKKPRVMLMVSKIGHCLNDLLFRYKSGLLPVEIPAIVSN 124 L F + +MN+ +D + + +LMVS+ GHCLNDLL+R+K G LP++I +VSN Sbjct: 62 LCDGFAAVAAPFEMNFNFYDNAHRVKTLLMVSRFGHCLNDLLYRWKIGALPIDIVGVVSN 121 Query: 125 HTDFYQLAASYNIPFHHLPLATGSSAQVKRAQEQRIMEIVEANQIDLVVLARYMQILSPE 184 H D+ ++ +++IPFHH+ + + K E+ +MEIVE +LVVLARYMQ+LS E Sbjct: 122 HFDYQKVVVNHDIPFHHIAVTKAN----KPEAERHLMEIVEDTNTELVVLARYMQVLSDE 177 Query: 185 MCEALRGRAINIHHSFLPSFKGAKPYYQAHDRGVKLIGATAHFVTGDLDEGPIIEQGVER 244 C+ + GR INIHHSFLPSFKGA PY QA++RGVKLIGATAH+VT +LDEGPIIEQ V R Sbjct: 178 FCQKMSGRIINIHHSFLPSFKGANPYKQAYERGVKLIGATAHYVTANLDEGPIIEQDVAR 237 Query: 245 VDHSMGPDTLTAIGRDIECVVLARAVKWFTEHRILLNGHKTVIF 288 + H+ +IGRD+E VLARAV HR LNG++TV+F Sbjct: 238 ITHAQNSADYVSIGRDVEAQVLARAVHAHIHHRSFLNGNRTVVF 281 >AGc4474 [F] COG0788 Formyltetrahydrofolate hydrolase Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 294 Score = 309 bits (791), Expect = 6e-84, Method: Compositional matrix adjust. Identities = 145/283 (51%), Positives = 203/283 (71%), Gaps = 5/283 (1%) Query: 6 YILTLSCLDQRGIVHRVSGFLADHGCNIIDSAQFGDAQSKLFFMRVHFASEDGAMSDAAL 65 Y+LT++C RGIV +SG+LA+ GCNI+DS+QF D ++ FFMRV F SE+GA S A+ Sbjct: 4 YVLTVACKSTRGIVAAISGYLAEKGCNIVDSSQFDDLETGKFFMRVSFISEEGA-SLQAI 62 Query: 66 RADFGVLGDSLQMNWQLHDAGKKPRVMLMVSKIGHCLNDLLFRYKSGLLPVEIPAIVSNH 125 F + + M ++ G++ + MLMVS+ GHCLNDLL+R+K G LP++I +VSNH Sbjct: 63 TEGFQPVSEKFGMASDIYPDGQRMKAMLMVSRFGHCLNDLLYRWKIGALPIDIVGVVSNH 122 Query: 126 TDFYQLAASYNIPFHHLPLATGSSAQVKRAQEQRIMEIVEANQIDLVVLARYMQILSPEM 185 D+ ++ +++IPFHH+ + + + K E ++M+++E + +LVVLARYMQ+LS EM Sbjct: 123 FDYQKVVVNHDIPFHHIKV----TKENKPKAEAQLMDLIETSGTELVVLARYMQVLSDEM 178 Query: 186 CEALRGRAINIHHSFLPSFKGAKPYYQAHDRGVKLIGATAHFVTGDLDEGPIIEQGVERV 245 C + G+ INIHHSFLPSFKGA PY QA++RGVKLIGATAH+VTGDLDEGPIIEQ RV Sbjct: 179 CRKMSGKIINIHHSFLPSFKGANPYKQAYERGVKLIGATAHYVTGDLDEGPIIEQDTVRV 238 Query: 246 DHSMGPDTLTAIGRDIECVVLARAVKWFTEHRILLNGHKTVIF 288 H+ + ++GRD+E VLARA+ HR +NG++TV+F Sbjct: 239 THAQSAEDYVSLGRDVESQVLARAIHAHIHHRTFINGNRTVVF 281