BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1469.p (382 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1161 [GEPR] COG0477 Permeases of the major facilitator superfa... 67 9e-11 BH0472 [GEPR] COG0477 Permeases of the major facilitator superfa... 66 2e-10 PA0334 [GEPR] COG0477 Permeases of the major facilitator superfa... 52 2e-06 ECs3206 [GEPR] COG0477 Permeases of the major facilitator superf... 46 1e-04 Z3585 [GEPR] COG0477 Permeases of the major facilitator superfam... 46 2e-04 >BH1161 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 406 Score = 66.6 bits (161), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 102/388 (26%), Positives = 161/388 (41%), Gaps = 36/388 (9%) Query: 14 RHAALSLSAALPCDIVLYLLLPMYADQFHVS-LAEAGVLLAANRLVRIAGYRWVASFYAR 72 R A+ + AL D ++ ++LP+Y ++F ++ + + GVLL+ NRL+R+ V FY Sbjct: 8 RWIAILTAIALLGDSMILIVLPLYWEEFGLTAIWQVGVLLSVNRLIRLPINPLVGWFYRT 67 Query: 73 RGDRPTCLMAVCTAVVCALGYTVASGFWALLPLRLLWGMAFAGLNLSTQSMSTSTAQGAA 132 R +A+ A+V L Y GF LL R+LWG+A+A + L T + Sbjct: 68 YERRTGFFIAMSLALVTTLAYGYVQGFIWLLIARILWGVAWAFIRLG--GYLTVLDHSNS 125 Query: 133 RRSGRSRGVIAIGPMLWLPTAALLAAHVGPRMVFGCVAMTALLGLLAAHRLPAHAYAPP- 191 R G G+ L L V + V T L A LP P Sbjct: 126 RNRGELIGLYNGLWGLGGLVGMLAGGIVVEQTSIAFV--TTLFAGAACFSLPTLFKVIPR 183 Query: 192 ---QPRRWKLPNALDWW----------SFLEGLTLDGLFIVGLAYMSKQSFGAD------ 232 + R K DW+ SF GL + G+F L+ ++ + Sbjct: 184 SVSEQVRDKTDGKGDWFSIHTGSILLLSFTTGLVIFGVFATTLSPFVERMIDDNWTWHGL 243 Query: 233 ---GELVAGVLMALRYAGEIVLSPLGGWLAERFGAVKVLVTLSLATCVALVGFGGGLLWL 289 VAG++ A+R+A + ++P+ G +R K V S+ +A + F G + Sbjct: 244 VIGAATVAGLIQAVRWAWDPFVAPMVGKRLDRMRT-KGPVVFSMLLMIASLFFIAGSVHD 302 Query: 290 FAGLIVILRALQL------PLLAPIVAARTPPGQRVHALAGRAIWRDIGAGLGPMLAGLL 343 F V L QL L + A RV + I D+GA LGP++ L+ Sbjct: 303 FVLASVFLLVFQLISTIFVTLTDSLAAEVANQTDRVRMMTAHTIAIDLGAALGPLIGFLV 362 Query: 344 LPVMSSLWLYGLAAAALALAAIA-CGRE 370 + + +LY + ++ L L AI C E Sbjct: 363 VATVHLSFLYFMTSSWLLLLAIYWCWYE 390 >BH0472 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 417 Score = 65.9 bits (159), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 101/382 (26%), Positives = 174/382 (45%), Gaps = 36/382 (9%) Query: 14 RHAALSLSAALPCDIVLYLLLPMYADQFHV-SLAEAGVLLAANRLVRIAGYRWVASFYAR 72 + AL + L D +LY+ LP+Y + + SL E G++L+ NR VRI V Y Sbjct: 14 KVVALVTALCLLGDSLLYVALPIYYREVGLQSLWEVGIILSLNRFVRIPINPLVGKCYQH 73 Query: 73 RGDRPTCLMAVCTAVVCALGYTVASGFWALLPLRLLWGMAFAGLNLS--TQSMSTSTAQG 130 R L+AV +V +GY V GF+ + LRLLWG+A++ L L + +T Sbjct: 74 VTLRTGLLIAVSLTLVTTIGYGVGYGFFVWVILRLLWGIAWSFLRLGGLFTVLEEATDSN 133 Query: 131 AARRSGRSRGVIAIGPMLWLPTAALLAAHVG---PRMVFGCVAMTAL------LGLLAAH 181 + G+ G+ +G + + +LA+ +G ++FG +A+ A+ + LA Sbjct: 134 RGKLMGQYNGLYRLGSLGGMLGGGILASFIGLSATAIIFGVLAVLAIPYVLRYVPSLAQE 193 Query: 182 RLPAHAYAPPQPRRWKL--PNALDWWSFLEGLTLDGLFIVG--LAYMSKQSFGADGELV- 236 R + +R L +A+ S L L + G L+ + + +G +V Sbjct: 194 RTGQPEGDSTEKKRKGLYGRHAILAISSGLLLALFLQGLFGSTLSLLMLEHYGETIYIVG 253 Query: 237 --------AGVLMALRYAGEIVLSPL-GGWLAERFGAVKVLVTLSLATCVALVGFGGGLL 287 +GVL +R+ E L+ L G W G + + + + T +G+G +L Sbjct: 254 MIVGVTALSGVLQGVRWVWEPFLAVLFGHWSDGDRGRLPLFILFLIMTA---LGYGAMVL 310 Query: 288 ------WLFAGLIVILRALQLPLLAPIVAARTPPGQRVH-ALAGRAIWRDIGAGLGPMLA 340 WL A ++V++ + L L + + GQ + + ++ D+GA LGP+LA Sbjct: 311 SLPLIIWLAAVIVVMVASTALTTLIDALTSDVAKGQDANRVMTSYTVFLDVGAALGPLLA 370 Query: 341 GLLLPVMSSLWLYGLAAAALAL 362 LL + SL L++A + L Sbjct: 371 YFLLDIGLSLTFVYLSSAVIFL 392 >PA0334 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 412 Score = 52.0 bits (123), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 35/99 (35%), Positives = 54/99 (54%), Gaps = 1/99 (1%) Query: 17 ALSLSAALPCDIVLYLLLPMYADQFHVS-LAEAGVLLAANRLVRIAGYRWVASFYARRGD 75 AL + L D +LY+ LP+Y + + L + GVLL+ NRL+R+ + Y Sbjct: 17 ALVTALCLAGDSMLYIALPIYWHEVGLEALWQVGVLLSINRLIRLPFNPLIGRLYKHLAL 76 Query: 76 RPTCLMAVCTAVVCALGYTVASGFWALLPLRLLWGMAFA 114 + L+AV V+ GY +ASGF A + LR LWG+ ++ Sbjct: 77 KTGLLLAVVIGVLSTAGYGLASGFLAWVLLRGLWGIGWS 115 >ECs3206 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 392 Score = 45.8 bits (107), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 117/279 (41%), Gaps = 43/279 (15%) Query: 102 LLPLRLLWGMAFAGLNLSTQSMSTSTAQGAARRSGRSRGVIAIGPMLWLPTAALLAAHVG 161 LL L WG+ G S + MS + G A G +A+G P L+ +H G Sbjct: 129 LLTGALTWGLGIVGPKHSGKVMSWN---GMA-----IYGALAVGA----PLGLLIHSHYG 176 Query: 162 PRMVFGCVAMTAL-LGLLA------AHRLPAHAYAPPQPRRWKLPNALDWWSFLEGLTLD 214 F +A+T + L LLA ++PA A +P W + + W GL L Sbjct: 177 ----FAALALTTMALPLLAWACNGTVRKVPA--LAGERPSLWSVVGLI--WKPGLGLALQ 228 Query: 215 GLFIVGLAYMSKQSFGADGELVAGVLMALRYAGEIVLSPLGGWLAERFGAVKVLVTLSLA 274 G+ + F + G +AG + +V+ + GW+ +RFG VKV + L Sbjct: 229 GVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLV 288 Query: 275 TCVALVGFGGGLLWLFAGLIVILR---------ALQLPLLAPIVAARTPPGQRVHALAGR 325 V L+ LLW G V L +L P L V R P R AL G Sbjct: 289 ETVGLL-----LLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGY 343 Query: 326 AIWRDIGAGLGPMLAGLLLPVM--SSLWLYGLAAAALAL 362 A ++DI G+ LAG+L SS++L G +A L + Sbjct: 344 AAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGI 382 >Z3585 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 392 Score = 45.8 bits (107), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 81/279 (29%), Positives = 117/279 (41%), Gaps = 43/279 (15%) Query: 102 LLPLRLLWGMAFAGLNLSTQSMSTSTAQGAARRSGRSRGVIAIGPMLWLPTAALLAAHVG 161 LL L WG+ G S + MS + G A G +A+G P L+ +H G Sbjct: 129 LLTGALTWGLGIVGPKHSGKVMSWN---GMA-----IYGALAVGA----PLGLLIHSHYG 176 Query: 162 PRMVFGCVAMTAL-LGLLA------AHRLPAHAYAPPQPRRWKLPNALDWWSFLEGLTLD 214 F +A+T + L LLA ++PA A +P W + + W GL L Sbjct: 177 ----FAALALTTMALPLLAWACNGTVRKVPA--LAGERPSLWSVVGLI--WKPGLGLALQ 228 Query: 215 GLFIVGLAYMSKQSFGADGELVAGVLMALRYAGEIVLSPLGGWLAERFGAVKVLVTLSLA 274 G+ + F + G +AG + +V+ + GW+ +RFG VKV + L Sbjct: 229 GVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLV 288 Query: 275 TCVALVGFGGGLLWLFAGLIVILR---------ALQLPLLAPIVAARTPPGQRVHALAGR 325 V L+ LLW G V L +L P L V R P R AL G Sbjct: 289 ETVGLL-----LLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGY 343 Query: 326 AIWRDIGAGLGPMLAGLLLPVM--SSLWLYGLAAAALAL 362 A ++DI G+ LAG+L SS++L G +A L + Sbjct: 344 AAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGI 382