BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1428.p (1085 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1622_1 [T] COG0642 Signal transduction histidine kinase Rso R... 524 e-148 CC2988_1 [T] COG0642 Signal transduction histidine kinase Ccr Ca... 207 1e-52 slr2098_3 [T] COG0642 Signal transduction histidine kinase Syn S... 206 4e-52 rcsC_1 [T] COG0642 Signal transduction histidine kinase Eco Esch... 201 1e-50 ECs3107_1 [T] COG0642 Signal transduction histidine kinase Ecs E... 201 1e-50 >RSp1622_1 [T] COG0642 Signal transduction histidine kinase Rso Ralstonia solanacearum Length = 869 Score = 524 bits (1349), Expect = e-148, Method: Compositional matrix adjust. Identities = 326/863 (37%), Positives = 478/863 (55%), Gaps = 20/863 (2%) Query: 1 MPHKILARSERYYRRLLYSCASLLSVAIVCAMLFLGYSAFSQFRERQIASFTGKREQIKS 60 MP ++L ++ RY RR+LY C + LS+AIV A+L LG Q+ +RQ+A F ++++ Sbjct: 1 MPQRLLTKTGRYSRRVLYGCTAALSIAIVGAVLLLGRGIIDQYGDRQVARFVRTSGEVRT 60 Query: 61 EVDRLTARVIQFAEMYARLQHLYKKELLVLDSYADLIDAE-PIIRSPESLTVVPFSLLVG 119 EVD L+AR+ QFA++Y + +L + +++ YA + A+ + LT P +L+ Sbjct: 61 EVDGLSARLAQFADLYEGVWNLRQNDVVPTRRYAGKLAADRGATVTGADLTATPVTLISS 120 Query: 120 RDTATDRGRLANLLLLLRQASALPMFNPSAPGVTLDGFIYTGDAGFLAVSPPLSEEESDQ 179 D D RLA L +LR S P+ + GVTLDGF+YT DA FLA P L + Sbjct: 121 LDRPADGARLAMALRVLRDVSGAPLMDAQKLGVTLDGFLYTPDATFLAAFPALRPADLRS 180 Query: 180 VRQLGVSRFINAISAPVNTAFAAERERAAQAQGSNGQRVLWMSPTLSTPLRRAAVTRLAV 239 R+ G FI A V A+ A + G+R LW + A+V++L V Sbjct: 181 AREQGPQPFIRERIAAVEQRIASSAPEAVR-----GRRPLWYPADETNG--HASVSQLIV 233 Query: 240 RISLEKGDEATAVFSVPASQFRQFFLKDE-QTPGLFVFEGQGSTRLLSQPDERIDTAMMQ 298 + + T ++P +QF +FFL+ E + PG F+ G L P + + ++ Sbjct: 234 PMYRDNARVLTIALTLPDAQFTRFFLRKESRRPGFFLLSQTGQRSLGDLPADLEERRLLD 293 Query: 299 HILEHVRHDMAPHDLNGHFHDDGTFFIAQTIEGPEWVVVYIFTWRDVLAGLQGNFTTGAL 358 +L + F+ DG FF+++ I GP+W+ VY + W+DV + LQ F G + Sbjct: 294 TVLANADWSRQAGAEPTTFYKDGVFFVSRRIAGPDWIAVYAYRWQDVWSDLQHEFFAGMV 353 Query: 359 WGLFALLFVWVATLYFDRCVIGPLQKKALAMVETRQFSQTIIDTLPVGIAVYAHGSGELV 418 + + L +W YFD V PL A ++E FS+ IIDTLP+GI VY+ + ++ Sbjct: 354 FCVLVLGLLWATAAYFDLRVTRPLLSDAKKLIEAEHFSKAIIDTLPIGIGVYSPETDSIL 413 Query: 419 LRNAVTTQMLDQSALSASSFYAQILIAVRAADDL---RQSMIEAELPLRDGGVSHLGAVW 475 L N+V +ML + + + ++ R A+ + R S IE +G S++G Sbjct: 414 LENSVAVRMLGNVSNEQRLRFYRYVMHERDAEPVPGARHSFIEVRWERAEGQSSYIGVAS 473 Query: 476 SRTRFSGQDVLLLGLIDLNMQKAHEALMREAKSMADRANQAKSMFLAQVSHEIRTPLHGA 535 S TRF G+ +LLGL+D+N +KA+E L+ EAK AD AN+AKSMFLA V HEIRTPLHGA Sbjct: 474 SWTRFGGRSAVLLGLVDMNERKANEILLMEAKQTADEANRAKSMFLAIVGHEIRTPLHGA 533 Query: 536 IGHMELLAREHLSPSQHQRVELIRHAFDMLMSLVNDILDITKIETQSITLAAEELRVNDL 595 +GH+ELLAR LS Q + V++ +FD L++LVND+LD TK+E ++ ++ + N++ Sbjct: 534 MGHLELLARSALSLEQREWVDMTSRSFDALLTLVNDLLDSTKLEANALQISPVPMCPNEV 593 Query: 596 LEECAQLFAPLALDKGLQFHCLPCAALEQPVRGDPRRLLQILQNLVGNAVKFTASGGITL 655 LE CA+ F + G+ FHC+ L+ V GD +RL QILQNL+ NA KFT G IT+ Sbjct: 594 LERCARSFGAAIVQGGVAFHCITDPDLDLVVDGDDQRLTQILQNLLSNAAKFTERGTITI 653 Query: 656 SAQLLQSSQDKSIVRFEVADTGIGISPSARQRIFKSLQQADDSISQRFGGTGLGLSLCRR 715 +++ L+ K RFEVADTGIGI + + IF L QADDSIS+RFGGTGLGL LCR Sbjct: 654 ASRCLKREDGKVWARFEVADTGIGIPAAMQSTIFNPLAQADDSISRRFGGTGLGLFLCRN 713 Query: 716 LAELMGGDITLDSEVGKGSTFGAEISLARIQQAEQACVPPLQGRKVVVHVQDPATAAMLR 775 LA LMGG I++ SE G GS F ++ A+ +A P L G V + ML Sbjct: 714 LAHLMGGRISVRSEPGIGSAFRVDLPFAQNTRAPAPPPPVLTGLSVELLCPVSQWRGMLA 773 Query: 776 AYLQHWGAEFVAPASATPAM-LHL---VAPDGIAAFMSTPMNTS--IASVLIRPDVVRQS 829 L+ WGA V PA A+ A LH+ V DG A+ + + T + +V + + Sbjct: 774 ERLRRWGAT-VRPAEASAAEPLHIRLAVEADG-RAWHAADLGTVPLLGTVFVTAKGPLHA 831 Query: 830 SSMGHWRQVSAFDRRAWCSALAD 852 G +VS+F R +AL + Sbjct: 832 HRDGQKIEVSSFTREGLLAALTE 854 >CC2988_1 [T] COG0642 Signal transduction histidine kinase Ccr Caulobacter vibrioides Length = 451 Score = 207 bits (527), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 106/225 (47%), Positives = 151/225 (67%), Gaps = 3/225 (1%) Query: 512 RANQAKSMFLAQVSHEIRTPLHGAIGHMELLAREHLSPSQHQRVELIRHAFDMLMSLVND 571 +A++AKS FLA +SHEIRTP++G + + L+R L P Q ++ L++ + + LM+L+ND Sbjct: 194 KASEAKSAFLAMISHEIRTPMNGVLAMTDALSRADLGPDQARQTALLKRSGEDLMTLLND 253 Query: 572 ILDITKIETQSITLAAEELRVNDLLEECAQLFAPLALDKGLQFHCLPCAALEQPVRGDPR 631 +LDI++IE + + + + +LL + L+ P A DKGL L+ GDP Sbjct: 254 VLDISRIEAGKLEIECQPFDLPELLGDLRALWTPAATDKGLDLVLTIAPGLDAYRLGDPT 313 Query: 632 RLLQILQNLVGNAVKFTASGGITLSAQLLQSSQDKSIVRFEVADTGIGISPSARQRIFKS 691 RL QIL NLV NAVKFT SGG+ LSA + + V F+VADTGIG++P + R+F+S Sbjct: 314 RLRQILGNLVSNAVKFTRSGGVALSA---RPGEAPGAVVFDVADTGIGMTPEQQGRLFQS 370 Query: 692 LQQADDSISQRFGGTGLGLSLCRRLAELMGGDITLDSEVGKGSTF 736 QAD SI++RFGG+GLGLS+C +LA LM G IT+DS++G GSTF Sbjct: 371 FSQADASIARRFGGSGLGLSICSQLATLMDGAITVDSDLGSGSTF 415 >slr2098_3 [T] COG0642 Signal transduction histidine kinase Syn Synechocystis Length = 280 Score = 206 bits (523), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 114/273 (41%), Positives = 169/273 (61%), Gaps = 2/273 (0%) Query: 473 AVWSRTRFSGQDVLLLGLIDLNMQKAHEALMREAKSMADRANQAKSMFLAQVSHEIRTPL 532 A + T + GQ +L L D+ KA EA M+ AK +A+ A++ K+ FLA +SHEIRTP+ Sbjct: 3 ATFLATDYEGQKGILGWLADITPIKAAEAEMKRAKELAEEASRIKADFLANMSHEIRTPM 62 Query: 533 HGAIGHMELLAREHLSPSQHQRVELIRHAFDMLMSLVNDILDITKIETQSITLAAEELRV 592 + IG L + L+P Q + + IR + L+ ++NDILD +KIE + + + + + Sbjct: 63 NAVIGMTHLALKTDLTPRQREYLHKIRFSGQHLLGVINDILDFSKIEAGKLPMESIDFDL 122 Query: 593 NDLLEECAQLFAPLALDKGLQFHCLPCAALEQPVRGDPRRLLQILQNLVGNAVKFTASGG 652 + +L+ A L + A +KGL+ L + GDP RL QIL N NAVKFT G Sbjct: 123 DKVLDNVATLISEKATNKGLELLFDIDRNLPRHFIGDPLRLGQILINYANNAVKFTEQGD 182 Query: 653 ITLSAQLLQSSQDKSIVRF-EVADTGIGISPSARQRIFKSLQQADDSISQRFGGTGLGLS 711 IT+ +L Q +D+ +V + V DTGIGI P +F S QQAD S ++ FGGTGLGL+ Sbjct: 183 ITIVVRL-QEYRDQDVVLYLAVKDTGIGIKPEHIANLFNSFQQADSSTTRNFGGTGLGLA 241 Query: 712 LCRRLAELMGGDITLDSEVGKGSTFGAEISLAR 744 +C+R+AELMGG++ ++SE G+GSTF A++ L + Sbjct: 242 ICKRIAELMGGEVGVESEYGQGSTFWAKVCLQK 274 >rcsC_1 [T] COG0642 Signal transduction histidine kinase Eco Escherichia coli K12 Length = 700 Score = 201 bits (510), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 119/396 (30%), Positives = 204/396 (51%), Gaps = 19/396 (4%) Query: 374 FDRCVIGPLQKKALAMVETRQFSQTIIDTLPVGIAVYAHGSGELVLRNAVTTQMLDQSAL 433 ++R + P + AL + E QF++ I+ + PVGI + G +L N + L+ Sbjct: 321 YERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLNMLTH 380 Query: 434 SASSFYAQILIA--VRAADDLRQSMIEAELPLRDGGVSHLGAVWSRTRFSGQDVLLLGLI 491 QI+ V D L + ++L + +R+ ++V + L+ Sbjct: 381 EDRQRLTQIICGQQVNFVDVLTSNN------------TNLQISFVHSRYRNENVAICVLV 428 Query: 492 DLNMQKAHEALMREAKSMADRANQAKSMFLAQVSHEIRTPLHGAIGHMELLAREHLSPSQ 551 D++ + E ++E A++A+Q+KSMFLA VSHE+RTPL+G IG+++LL + L Sbjct: 429 DVSSRVKMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGV 488 Query: 552 HQRVELIRHAFDMLMSLVNDILDITKIETQSITLAAEELRVNDLLEECAQLFAPLALDKG 611 + V + ++ +L+ +++DILD +KIE++ + + E +++ + PL + K Sbjct: 489 DRLVTAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQ 548 Query: 612 LQFHCLPCAALEQPVRGDPRRLLQILQNLVGNAVKFTASGGITLSAQLLQSSQDKSIVRF 671 L +C + + GDP RL Q++ NL+ NA+KFT +G I L + D + Sbjct: 549 LGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVR-----ADGDYLSI 603 Query: 672 EVADTGIGISPSARQRIFKSLQQADDSISQRFGGTGLGLSLCRRLAELMGGDITLDSEVG 731 V DTG+GI R+F Q + + F GTGLGL++C +L +M GDI++DSE G Sbjct: 604 RVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPG 663 Query: 732 KGSTFGAEISLARIQQAEQACVPPLQGRKVVVHVQD 767 GS F I L Q ++ V L G++ + V++ Sbjct: 664 MGSQFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRN 699 >ECs3107_1 [T] COG0642 Signal transduction histidine kinase Ecs Escherichia coli O157:H7 Length = 700 Score = 201 bits (510), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 119/396 (30%), Positives = 204/396 (51%), Gaps = 19/396 (4%) Query: 374 FDRCVIGPLQKKALAMVETRQFSQTIIDTLPVGIAVYAHGSGELVLRNAVTTQMLDQSAL 433 ++R + P + AL + E QF++ I+ + PVGI + G +L N + L+ Sbjct: 321 YERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLNMLTH 380 Query: 434 SASSFYAQILIA--VRAADDLRQSMIEAELPLRDGGVSHLGAVWSRTRFSGQDVLLLGLI 491 QI+ V D L + ++L + +R+ ++V + L+ Sbjct: 381 EDRQRLTQIICGQQVNFVDVLTSNN------------TNLQISFVHSRYRNENVAICVLV 428 Query: 492 DLNMQKAHEALMREAKSMADRANQAKSMFLAQVSHEIRTPLHGAIGHMELLAREHLSPSQ 551 D++ + E ++E A++A+Q+KSMFLA VSHE+RTPL+G IG+++LL + L Sbjct: 429 DVSSRVKMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGV 488 Query: 552 HQRVELIRHAFDMLMSLVNDILDITKIETQSITLAAEELRVNDLLEECAQLFAPLALDKG 611 + V + ++ +L+ +++DILD +KIE++ + + E +++ + PL + K Sbjct: 489 DRLVTAMNNSSSLLLKIISDILDFSKIESEQLMIEPREFSPREVMNHITANYLPLVVRKQ 548 Query: 612 LQFHCLPCAALEQPVRGDPRRLLQILQNLVGNAVKFTASGGITLSAQLLQSSQDKSIVRF 671 L +C + + GDP RL Q++ NL+ NA+KFT +G I L + D + Sbjct: 549 LGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVR-----ADGDYLSI 603 Query: 672 EVADTGIGISPSARQRIFKSLQQADDSISQRFGGTGLGLSLCRRLAELMGGDITLDSEVG 731 V DTG+GI R+F Q + + F GTGLGL++C +L +M GDI++DSE G Sbjct: 604 RVRDTGVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPG 663 Query: 732 KGSTFGAEISLARIQQAEQACVPPLQGRKVVVHVQD 767 GS F I L Q ++ V L G++ + V++ Sbjct: 664 MGSQFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRN 699