BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1366.p (302 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA485 [GER] COG0697 Permeases of the drug/metabolite transport... 257 2e-68 PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 254 2e-67 YPO2761 [GER] COG0697 Permeases of the drug/metabolite transport... 253 3e-67 RSp1638 [GER] COG0697 Permeases of the drug/metabolite transport... 249 7e-66 AGc4446 [GER] COG0697 Permeases of the drug/metabolite transport... 130 5e-30 >AGpA485 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 309 Score = 257 bits (656), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 142/295 (48%), Positives = 202/295 (68%), Gaps = 2/295 (0%) Query: 2 RSDLSYKSLCFPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARSTWA 61 + + K L F L AVLIW GNT++SK++AG IAP I+F RW +A ++++P + R W Sbjct: 4 EAPMPVKYLLFSLLAVLIWVGNTIVSKLAAGAIAPGTIAFERWFIAFVILTPLVYRDAWR 63 Query: 62 ARAQIRPHLGKILVLALLGMVLYQSLAYFAAATASATSMGIISSLMPLMTLVLSIKLLAE 121 R I HL K+++L LLGM Q L Y+AA +AT+M I+ SL+PL+TL+LS LAE Sbjct: 64 HRRTIAAHLPKLILLGLLGMAACQGLGYYAAGLTTATNMAIMLSLVPLLTLILSAVFLAE 123 Query: 122 PPTVGTLAGGILSLFGLAVLIGRGHPLALFEQGVVAGDLLMLAATVAYGLYGVMLRRWAL 181 P+ + GGI+SL G+ +++G+G P L QGV GD +MLAA +AY YG++LRRWA+ Sbjct: 124 RPSSLAVIGGIISLSGIFIVLGQGDPSRLLSQGVGRGDAMMLAAVLAYAGYGILLRRWAI 183 Query: 182 PLRTWQLLYLQVLMATVLLFPGFLLGHHSPITRANLPILLYAGIGASIISQFLWMRGVVH 241 PL TW +Y+Q+ A VLL P +LL S +T N ++LYA I SI++ F+WM V H Sbjct: 184 PLATWTSIYVQIGAAVVLLVPSYLLSAPSALTLPNTAMVLYAAIPGSILAPFVWMTAVKH 243 Query: 242 LGASRCAIFVNLMPIFTVIIAVLALGESLHGYHALGGSITLVGVMLAQV--FKQR 294 LGA+R AIF+NL+PIFT I+A + LGE+L+ YH LGG +T+ G++L Q F+++ Sbjct: 244 LGAARTAIFMNLIPIFTAIVAAIFLGEALYIYHLLGGGMTVAGIILVQRKPFREK 298 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 254 bits (649), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 143/283 (50%), Positives = 197/283 (69%) Query: 12 FPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARSTWAARAQIRPHLG 71 FPL AV IWAGNTV++K++ G+I P +I F+RW+L L ++PF+ R I +LG Sbjct: 5 FPLLAVFIWAGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILANLG 64 Query: 72 KILVLALLGMVLYQSLAYFAAATASATSMGIISSLMPLMTLVLSIKLLAEPPTVGTLAGG 131 K +VL LLGM +YQSLAY+AAA SAT+MGII SLMPLM+L L+ +LA G L G Sbjct: 65 KFVVLGLLGMAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGALLGA 124 Query: 132 ILSLFGLAVLIGRGHPLALFEQGVVAGDLLMLAATVAYGLYGVMLRRWALPLRTWQLLYL 191 ++SL G+ ++I +GH AL E GV GD +M+ AT+AY +Y V+L++W+L L QLLYL Sbjct: 125 LVSLAGVVLVISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQLLYL 184 Query: 192 QVLMATVLLFPGFLLGHHSPITRANLPILLYAGIGASIISQFLWMRGVVHLGASRCAIFV 251 QVL+A + L P +LL + + ANLP++LYA + ASI++ WM GV LG SR A+F Sbjct: 185 QVLVAILALLPLYLLSPRTGLNAANLPLVLYAALFASIVAALAWMHGVARLGPSRMALFF 244 Query: 252 NLMPIFTVIIAVLALGESLHGYHALGGSITLVGVMLAQVFKQR 294 NL+PI T IA L LGE L +H +GG++TL GV+LA+ +++R Sbjct: 245 NLLPIITACIATLVLGERLTVHHLVGGALTLAGVLLAEFWQRR 287 >YPO2761 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ype Yersinia pestis Length = 305 Score = 253 bits (647), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 148/288 (51%), Positives = 204/288 (70%) Query: 9 SLCFPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARSTWAARAQIRP 68 ++ FPL AV+IW+ N V+SK+SA I P ISFYRW+LA L +SPFL IR Sbjct: 2 NVLFPLFAVIIWSVNAVVSKISATAIDPAAISFYRWLLALLTLSPFLLLGVVRNWQAIRV 61 Query: 69 HLGKILVLALLGMVLYQSLAYFAAATASATSMGIISSLMPLMTLVLSIKLLAEPPTVGTL 128 + K+++L +LGMVLYQSLAY+AA + SA MGI+SSL+PL+T+++SI LL PTVG Sbjct: 62 YWWKLMLLGMLGMVLYQSLAYYAAHSVSALFMGILSSLIPLLTVLISIVLLRVAPTVGIA 121 Query: 129 AGGILSLFGLAVLIGRGHPLALFEQGVVAGDLLMLAATVAYGLYGVMLRRWALPLRTWQL 188 G +LSL GL LI G+P+ L + G+ G+L+ML A+ +Y LYGV+ +RWA+ L WQ Sbjct: 122 LGSLLSLGGLVWLISAGNPVQLLQHGIGKGELMMLGASASYALYGVLTKRWAIQLPNWQS 181 Query: 189 LYLQVLMATVLLFPGFLLGHHSPITRANLPILLYAGIGASIISQFLWMRGVVHLGASRCA 248 LY+Q++ VLL PGFL+ +T N+P++L+AGI ASI++ +LW++GV+ LGA+ + Sbjct: 182 LYMQIVFGVVLLLPGFLMTPDVQLTAQNIPLVLFAGIPASILAPYLWIQGVMRLGANTAS 241 Query: 249 IFVNLMPIFTVIIAVLALGESLHGYHALGGSITLVGVMLAQVFKQRLR 296 IF+NL P+FT IIAV+ L E LH YH +GG ITL GV+LAQ + LR Sbjct: 242 IFMNLTPVFTAIIAVVFLHEQLHSYHLIGGGITLAGVVLAQRLRSPLR 289 >RSp1638 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 297 Score = 249 bits (635), Expect = 7e-66, Method: Compositional matrix adjust. Identities = 129/291 (44%), Positives = 195/291 (67%), Gaps = 6/291 (2%) Query: 12 FPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARSTWAARAQIRPHLG 71 +PL AVL+WA NT++SK +AGV+ P IS YRWV+AA +++PF AR W R + P L Sbjct: 5 YPLLAVLVWAANTIVSKAAAGVLDPAAISLYRWVIAAAVLTPFWARPLWRQRRDVLPWLP 64 Query: 72 KILVLALLGMVLYQSLAYFAAATASATSMGIISSLMPLMTLVLSIKLLAEPPTVGTLAGG 131 ++ VLALLG+V+YQ L+Y+AA + SAT++G+I +L+P++ L+++ + +P +AG Sbjct: 65 RLSVLALLGLVMYQCLSYYAAYSTSATNIGVICALIPMLGLIINGVVFRQPVGAPAVAGI 124 Query: 132 ILSLFGLAVLIGRGHPLALFEQGVVAGDLLMLAATVAYGLYGVMLRRWALPLRTWQLLYL 191 +SL G+ L+GRGHP +LF+ GV GD+L+L + AY LY ++ RRWA P W LYL Sbjct: 125 AVSLLGVLYLLGRGHPASLFDGGVNRGDVLVLIGSAAYALYNILYRRWAPPFGQWLNLYL 184 Query: 192 QVLMATVLLFPGFLLGHHSPITRANLPILLYAGIGASIISQFLWMRGVVHLGASRCAIFV 251 Q L+A V+L P I + + ++L+AGIGASI++ + WM G+ LG+ R + + Sbjct: 185 QALLAVVMLLPLAFTARSLAIPQQGIGMVLFAGIGASIVAMYWWMLGLARLGSERTVVMM 244 Query: 252 NLMPIFTVIIAVLALGESLHGYHALGGSITLVGVMLAQ------VFKQRLR 296 NL+P+FT ++A LGE++HGYH +GG + L+GV L Q + + RLR Sbjct: 245 NLLPVFTALMASAMLGETIHGYHWIGGGLILLGVSLVQGIVTLPMGRDRLR 295 >AGc4446 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 302 Score = 130 bits (326), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 93/285 (32%), Positives = 151/285 (52%), Gaps = 19/285 (6%) Query: 16 AVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLM----SPFLARSTWAARAQIRPHLG 71 A L W GNTV K++ G I+P +F RWVLA ++ P L + W Q P+ Sbjct: 19 ATLCWGGNTVAGKLAVGHISPMAFTFLRWVLAVAIIFAISVPQLIKD-WPVVKQRLPYF- 76 Query: 72 KILVLALLGMVLYQSLAYFAAATASATSMGIISSLMPLMTLVLSIKLLAEPPTVGTLAGG 131 VL +G + Y A SA + +I + +P++ VL+ L G +AG Sbjct: 77 --FVLGSVGYTAFNVFLYTALQHTSAINAAVIQAGIPMVIFVLNFVLFRTRVLFGQIAGF 134 Query: 132 ILSLFGLAVLIGRGHPLALFEQGVVAGDLLMLAATVAYGLYGVMLRRWALPLRTWQLL-- 189 L++ G+A+L G PL+L + + GD +ML A + Y +Y V+LR W P W+ L Sbjct: 135 CLTISGVALLASHGDPLSLLQLEMNVGDAVMLLAVLVYAIYTVILR-WK-PAVDWRTLMA 192 Query: 190 ---YLQVLMATVLLFPGFLLGHHSPI--TRANLPILLYAGIGASIISQFLWMRGVVHLGA 244 + +L + L+F F + S I + +++YAGI AS+I+Q L+++GV +GA Sbjct: 193 IPAFFALLTSVPLVF--FEMSRESLIWPDQKGWMLVVYAGIFASLIAQILYIKGVEQIGA 250 Query: 245 SRCAIFVNLMPIFTVIIAVLALGESLHGYHALGGSITLVGVMLAQ 289 +R +F+NL+P+F +++V L E+LH Y + L G+ +A+ Sbjct: 251 NRAGLFINLVPVFGTLLSVFVLSETLHTYQIAALFMALAGIAVAE 295