BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1365.p (446 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll8348 [GEPR] COG0477 Permeases of the major facilitator superf... 447 e-125 BMEII0596 [GEPR] COG0477 Permeases of the major facilitator supe... 429 e-120 SMc00813 [GEPR] COG0477 Permeases of the major facilitator super... 410 e-114 AGc1103 [GEPR] COG0477 Permeases of the major facilitator superf... 402 e-112 mll1728 [GEPR] COG0477 Permeases of the major facilitator superf... 333 5e-91 >mll8348 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 473 Score = 447 bits (1150), Expect = e-125, Method: Compositional matrix adjust. Identities = 237/440 (53%), Positives = 312/440 (70%), Gaps = 1/440 (0%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 MDSTVI+TSLP +A+D+ PI+LKLALT+YLVSLA+FIPISGWMADRFG+ IFRAAI Sbjct: 18 MDSTVIATSLPAIAIDIHTSPIALKLALTAYLVSLAIFIPISGWMADRFGAKNIFRAAIA 77 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 VF++GS+ C +S +LP FV +RFLQGIGGAMM PVGRLV++R+ K +LV A+S+LT+PA Sbjct: 78 VFIVGSVACALSGSLPAFVVSRFLQGIGGAMMTPVGRLVLVRATPKSDLVAAMSWLTVPA 137 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFVL 180 L GP++GPP+GGFITTYF W WIF IN+PI ++G++LATRF+P+ ++ + PLDF GFVL Sbjct: 138 LVGPLVGPPIGGFITTYFTWHWIFLINVPIGLVGIWLATRFLPETESMETPPLDFIGFVL 197 Query: 181 SALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVWHARRATAPLIDLALLKIPT 240 S L S ++ GL+ + V G L A Y+ HARRA PL+ L L + Sbjct: 198 SGLAASGVVFGLSVVSLPYLPPATGFITVGVGLLSGALYLMHARRAKNPLLALELFRNQV 257 Query: 241 LRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAARFLR 300 R+ V GGSL+R+GIGA+PFLLPLM Q+GFG TPF SG++T SA GA+ MK + A R Sbjct: 258 FRSSVLGGSLFRIGIGAVPFLLPLMFQIGFGLTPFQSGMITFVSAVGAIGMKFVTALIFR 317 Query: 301 RFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLNAISYADV 360 GFRRVL++ + + FTP TPY+LM+ ILL+GG RS+ FT +NA+SYA+V Sbjct: 318 VAGFRRVLIIGSLVAAASIAIYGLFTPETPYVLMLAILLVGGFIRSMFFTGVNALSYAEV 377 Query: 361 DNLRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEIQGHSELVAQDFWPAFLVVAAVAS 420 S+AT + +V QQLSI +GV LAG L++S I G L+ DF AF +VAAV++ Sbjct: 378 SAEDTSKATPITAVFQQLSIALGVALAGGILEVSTSIHG-GPLMLGDFHIAFFIVAAVSA 436 Query: 421 LALLMLRQLPPNAGAEMAGQ 440 A L +L P+AG ++G Sbjct: 437 AASLSFMRLAPDAGNAVSGH 456 >BMEII0596 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 469 Score = 429 bits (1103), Expect = e-120, Method: Compositional matrix adjust. Identities = 227/449 (50%), Positives = 302/449 (67%), Gaps = 5/449 (1%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 MDS VISTSLP +A D+ PI+LKLALT+YLV+LAVFIP+SGWMADRFG+ +FRAAI Sbjct: 18 MDSNVISTSLPAIAADIGTSPIALKLALTAYLVALAVFIPVSGWMADRFGAKNVFRAAIA 77 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 VF++GSI C S++LP FV ARFLQG+GGAMM PVGRLV++RS + LV A+++LTIPA Sbjct: 78 VFVVGSIACAASNSLPAFVIARFLQGMGGAMMTPVGRLVLIRSTPRNELVSAMAWLTIPA 137 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFVL 180 + GP++GPP+GGFITT+ W WIF IN+PI ++G++ AT F+PD + + LD+ GF L Sbjct: 138 MVGPLVGPPVGGFITTFLTWHWIFLINVPIGMIGIWFATHFLPDNEERIIKRLDWPGFFL 197 Query: 181 SALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVWHARRATAPLIDLALLKIPT 240 S S ++ GL+ + + A + G L YV HARR PL++L L Sbjct: 198 SGFAMSGVVFGLSVVSLPALPPVIGFATLAVGMLCTVLYVLHARRTPDPLLNLRLFDNQV 257 Query: 241 LRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAARFLR 300 R+ VFGGS++R GIGAIPFLLPLM QLGFG TPF SG++T SA GA+ MK A R Sbjct: 258 FRSAVFGGSIFRFGIGAIPFLLPLMFQLGFGLTPFQSGMMTFVSAIGAISMKFGAKRIFT 317 Query: 301 RFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLNAISYADV 360 R FRR L+ + + TFTP TPY +++ LL+GG RSL FT +NA+++A++ Sbjct: 318 RISFRRALMGGSLISAAFIAVNGTFTPATPYWIIIGFLLVGGFARSLFFTGVNALAFAEI 377 Query: 361 DNLRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEIQGHSELVAQDFWPAFLVVAAVAS 420 N + SQAT + +VAQQ+SI +GV LAG L++S ++G + L DF F VVA V+ Sbjct: 378 PNEKTSQATPLTAVAQQVSIAIGVALAGGILEISTMLRG-APLALVDFHIGFFVVACVSV 436 Query: 421 LALLMLRQLPPNAGAEMAG----QEENKP 445 LA +L P+AG E+A + KP Sbjct: 437 LAFFWFARLAPDAGKELATPSVIRHHGKP 465 >SMc00813 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 470 Score = 410 bits (1055), Expect = e-114, Method: Compositional matrix adjust. Identities = 212/441 (48%), Positives = 296/441 (67%), Gaps = 1/441 (0%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 MDSTVISTSLP +A DM V PI+LKLALTSY+V+LA+FIP+SGWMADRFG+ IFRAAI Sbjct: 18 MDSTVISTSLPAIARDMGVGPITLKLALTSYMVALAIFIPLSGWMADRFGAKRIFRAAIL 77 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 VF+ GS+ C ++ +L FV ARFLQG+GGAMM PV RLV++RS + LV A++ LTIPA Sbjct: 78 VFIAGSVFCAVADSLFAFVVARFLQGMGGAMMTPVARLVLVRSAPRSELVSAMALLTIPA 137 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFVL 180 L GP+ GPPLGGFITTYF W WIF IN+P+ ++G +L+ ++P+++ P+D GF+L Sbjct: 138 LVGPLAGPPLGGFITTYFSWHWIFLINVPVGIVGYFLSGIYLPEMERRNPPPVDIIGFLL 197 Query: 181 SALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVWHARRATAPLIDLALLKIPT 240 + + ++ GL+ + + +A V AG Y++HARR AP++DL L + Sbjct: 198 GGIAAAGVVFGLSVISLPALPPAIGIASVSAGVAASLLYIFHARRHPAPVLDLKLFRDGA 257 Query: 241 LRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAARFLR 300 RA GG+++R+ +GA+PFL+PLMLQ+GFG +PF SGL+T A GA+ K +A R Sbjct: 258 FRAASIGGTIFRISVGAVPFLMPLMLQVGFGLSPFQSGLITFVGAVGAITTKFLARRVFA 317 Query: 301 RFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLNAISYADV 360 GFR LL+ + + A FTP TPYLL++ +LLI G RS FT +NA+S+AD+ Sbjct: 318 FAGFRTTLLIAAVIAAVTTFANGFFTPATPYLLLISVLLIAGFARSFFFTGVNALSFADI 377 Query: 361 DNLRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEIQGHSELVAQDFWPAFLVVAAVAS 420 D+ S+ATSM++V QQ+S+ +GV +AG L+ + G L DF AF+++A Sbjct: 378 DDADASKATSMSAVLQQISLALGVAVAGAILEFETALSGK-PLELADFHVAFMIIAIANL 436 Query: 421 LALLMLRQLPPNAGAEMAGQE 441 LA + + NAGA ++G Sbjct: 437 LAAIPFIAMAKNAGASVSGHR 457 >AGc1103 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 475 Score = 402 bits (1034), Expect = e-112, Method: Compositional matrix adjust. Identities = 213/450 (47%), Positives = 311/450 (69%), Gaps = 7/450 (1%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 MDSTVI+TSLP +A D+ V PI+LKLALT+Y+V+LA+FIPISGWMAD++G+ IFR AI Sbjct: 28 MDSTVIATSLPAIAKDLHVGPITLKLALTAYMVALAIFIPISGWMADKYGAKKIFRIAIG 87 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 VF++GSI C +SS++ +FV +RFLQG+GGAMM PVGRLV+LR+ ++ LV A++ LTIP Sbjct: 88 VFVVGSICCAVSSSVFEFVLSRFLQGMGGAMMTPVGRLVLLRTTKRSELVSAMALLTIPG 147 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFVL 180 L GP+ GPP+GGFITTYF W WIF IN+PI ++G++L+T F+P+++ P+D KGF+L Sbjct: 148 LVGPLTGPPIGGFITTYFSWHWIFLINVPIGIIGIWLSTIFLPEIETTNPPPMDGKGFIL 207 Query: 181 SALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGYVW--HARRATAPLIDLALLKI 238 S + S ++ G++ + + +A V G F+ G+++ HA R AP++D + + Sbjct: 208 SGIAASGVVFGVSVVSLPALPPAIGIASTVIG--FICGFLYMRHAARHPAPILDFRIFQN 265 Query: 239 PTLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAARF 298 T RA GG+++R+ GAIPFL+PLMLQ+GFG PF SG++T A A GA+ K +A R Sbjct: 266 ATFRAASVGGTVFRISTGAIPFLMPLMLQIGFGLNPFQSGMITFAGAIGAITTKFMAKRV 325 Query: 299 LRRFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLNAISYA 358 GFR L+ G +G A + FTP TPY L+++ L+ G RS FT NA+SY+ Sbjct: 326 FAATGFRSTLIGAGIVGAFTTLANSFFTPETPYPLIMIFLVTAGFARSFFFTGSNALSYS 385 Query: 359 DVDNLRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEIQGHSELVAQDFWPAFLVVAAV 418 D+++ + SQATSMASV QQ+S+ +GV A L++S+ + G + L DF AF +VA V Sbjct: 386 DIEDSQASQATSMASVLQQISLALGVAFAASILEVSSMMSG-THLQLADFHIAFTIVALV 444 Query: 419 ASLALLMLRQLPPNAGAEMAGQ--EENKPA 446 + A++ + ++ AGA ++G + ++PA Sbjct: 445 SLFAIVPIIRMDAQAGAAVSGHRGKVSQPA 474 >mll1728 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 477 Score = 333 bits (854), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 193/443 (43%), Positives = 279/443 (62%), Gaps = 5/443 (1%) Query: 1 MDSTVISTSLPPLALDMKVDPISLKLALTSYLVSLAVFIPISGWMADRFGSLTIFRAAIC 60 +DST+ISTSLP + V +++ + +T Y++++AVF+P+SGW+ADRFG+ IF AI Sbjct: 33 LDSTIISTSLPQMGQSYGVPAVAMSVGITVYMLTMAVFVPLSGWLADRFGARNIFLVAIA 92 Query: 61 VFMLGSILCGMSSTLPQFVAARFLQGIGGAMMVPVGRLVILRSVEKVNLVKALSYLTIPA 120 +F L S+ CG S L QFVAAR +QG+G A+M PVGR+++LR+ K L+ A + +T PA Sbjct: 93 LFTLASLACGFSQNLTQFVAARAVQGLGSALMTPVGRILVLRNASKSELLNATALITWPA 152 Query: 121 LFGPVLGPPLGGFITTYFHWRWIFFINIPISVLGLYLATRFIPDLKAEQVSPLDFKGFVL 180 LF PV+GP LGGFITT W W FFINIP+ ++GL L RFIP + PLD+ GF L Sbjct: 153 LFAPVVGPVLGGFITTTLSWHWNFFINIPLGLIGLALVARFIPGDRVANPKPLDWPGFFL 212 Query: 181 SALGCSLLMMGLATAGRHLVSGDVALACVVAGTLFLAGY--VWHARRATAPLIDLALLKI 238 ++LG + L+ GL H G + ++A + + G+ V H RRA PL+DL+ K+ Sbjct: 213 TSLGLACLLYGLERIA-HPEDGMLPTVLLIAAGIVI-GWLAVRHLRRAPHPLLDLSSFKV 270 Query: 239 PTLRAGVF-GGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCASAAGAMFMKTIAAR 297 T G+++RV I A PFLLPL+ QLGFG +P +GL+ A G + MKT+ Sbjct: 271 LTFAISTLAAGTIFRVAINATPFLLPLLFQLGFGLSPVDAGLMILAYFVGNLGMKTVTTP 330 Query: 298 FLRRFGFRRVLLVNGALGVLGLCAIATFTPTTPYLLMVLILLIGGCFRSLQFTSLNAISY 357 LRRFGFR V++VNG + + A +P TP L+V+++LI G RS+QFT+LN +++ Sbjct: 331 TLRRFGFRSVMVVNGIIASASIMACGVISPQTPQALVVVLMLIAGLSRSMQFTALNTLAF 390 Query: 358 ADVDNLRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEIQGHSELVAQDFWPAFLVVAA 417 AD+D R S A +++S+ QQ+++ GV +A L +S + L DF AF V+ A Sbjct: 391 ADIDAARRSSAATLSSMLQQVAMLFGVAVAAAILNLSQIARAQPSLDLVDFRIAFFVIGA 450 Query: 418 VASLALLMLRQLPPNAGAEMAGQ 440 + +A L LP AGAE++G Sbjct: 451 IGLVAALRFLVLPRAAGAEVSGH 473