BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1362.p (1078 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1418 0.0 YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1266 0.0 ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1240 0.0 yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1238 0.0 ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1234 0.0 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1418 bits (3670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 713/1057 (67%), Positives = 862/1057 (81%), Gaps = 47/1057 (4%) Query: 1 MNISLPFIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMA 60 MN+S FI RP+AT LLTIG+ALAGI AF LLPVSPLPQVD+PTIS++AS+PGASPETMA Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 ATVATPLERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLP 120 ATVATPLER++G IAG+TEMTS S+ STR+TLQFDL+RDIDGAARDVQAA+NA+R+LLP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 TGMPSNPTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGS 180 +G+PSNPTYRKVNPADAPI+IL +TSDT ++G++YDAA +I+AQKLSQ+ GVGQV++GG+ Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 SQPAVRIELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDADRNWQIYANDQAKTAAE 240 S PAVR+ELNPTALNKYGI + VRT + ATNAN+PKG+LE +R W +YANDQA+ A E Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 YAPLIVSYRNGTPVRVQDVAEVRDSVADVRNAGSANGKPSVLIIINRQPGANIIDTVDNV 300 Y PLI++YRNG PVR+ DVAEV DSV D+RN GSANGKPSVL+IINRQPGANIIDTVD + Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 301 RELLPQLQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATL 360 +LP L+ +IP+ I++ V++DRTPTIRASL++ E TLMLS+ LVIMVV+LFLRN RATL Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 361 IPAVAVPVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRHIEAGMKP 420 IP+VAVPVSLIGTFG+MYL G+SLDNLSLMALT+ATGFVVDDAIVVLEN+SRHIE GM+P Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVLENVSRHIENGMRP 420 Query: 421 YQAALLGAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLT 480 QAAL GAREVGFTV+SMS SLIAVFIP+LMM GIVGRLFREFA+TLSVAILVSL +SLT Sbjct: 421 MQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTLSVAILVSLAISLT 480 Query: 481 TTPMMCAQLLRHDPAADEARRQRRHPWLQKIADQSAAIFADMLLAYERSLAWALRAAPLM 540 TTPMMCA+LL+ PA++E W + ++ F +L Y SLAWALR + L Sbjct: 481 TTPMMCARLLK--PASEE-----EPGWFHR---KTEGFFNLLLDGYRHSLAWALRHSWLT 530 Query: 541 MVILVATIALNVHLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRAKLNEFIDIVKAD 600 ++IL+AT+ LN +LY +PKGFFPQQD GRL+G I+ DQAISFQAMR KL +FI IV+ D Sbjct: 531 LLILLATVCLNGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIVQQD 590 Query: 601 PAVSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVVGRLRIKTAKVAGARVFLVPVQD 660 PAV +VV FTGG + N G M++ LKPL+ERK SAD+V+ RLR K A+ GA +FL VQD Sbjct: 591 PAVENVVGFTGGSQINSGQMFIQLKPLAERKLSADQVINRLRGKLAREPGANLFLQAVQD 650 Query: 661 IRIGARQSDSEYEYSLKSDDVGLLRIWEPKIRLALTNLKELEDVSSDQQDNGLQTTLTID 720 IRIG R S+++Y+Y+L++D++ LR WEPKIR ALT +K L DV++D QD G QT L D Sbjct: 651 IRIGGRPSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTALVFD 710 Query: 721 RETAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPKYWQSPEILRDTYVS 780 R+ AM G+TP+ ID+ L++ FGQRQ+STIY+ +NQY VVMEAAP+YWQ+PE LRD Y+ Sbjct: 711 RDKAMALGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRDIYL- 769 Query: 781 LAGSSNLSPTTSSLSTPPALSASGQLNANTGLAQTLSTAPSKQVPLATFARFEPTTTSLA 840 ++ASG QVPL+TF+ + PT T LA Sbjct: 770 -------------------ITASG-----------------AQVPLSTFSHYGPTNTPLA 793 Query: 841 VNHDGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQSSTSSQ 900 VNH GQF ASTLSFNLA G SLS AT I AM ++GVPT+V G+F GTA AFQ S SSQ Sbjct: 794 VNHQGQFAASTLSFNLAPGASLSAATQQIQDAMNRIGVPTTVHGSFQGTARAFQDSLSSQ 853 Query: 901 PILILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMLTGTDFSLIALIGVIL 960 P+LIL AL+ +YIVLG+LYES +HPITI+STLPSAGVGALLAL++T TDFS+IALIGVIL Sbjct: 854 PVLILFALITIYIVLGVLYESYVHPITILSTLPSAGVGALLALIVTDTDFSVIALIGVIL 913 Query: 961 LIGIVKKNAIMMVDFAIDAERHRGLSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGH 1020 LIGIVKKNAIMM+DFA++AER +G+SP DAIF AC LRFRPI+MTTMAALLGA+PLA+GH Sbjct: 914 LIGIVKKNAIMMIDFALEAERSQGMSPADAIFHACVLRFRPILMTTMAALLGALPLALGH 973 Query: 1021 GDGAELRQPLGIAIVGGLVVSQLLTLYTTPVVYLYME 1057 GDGAELRQPLGI+IVGGL+VSQ+LTLYTTPVVYL ++ Sbjct: 974 GDGAELRQPLGISIVGGLLVSQILTLYTTPVVYLALD 1010 >YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1024 Score = 1266 bits (3276), Expect = 0.0, Method: Compositional matrix adjust. Identities = 653/1068 (61%), Positives = 807/1068 (75%), Gaps = 60/1068 (5%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FIQRP+ATTLLT+ I L+GI+ F LLPVSPLPQVDYP I +SASMPGA PETMA++VATP Sbjct: 7 FIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LERA+G IAGV EMTSTSS STRI LQFDLNRDI+GAARDVQAALNAA++LLP+GMPS Sbjct: 67 LERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK+NP+DAPI+I+ +TSDT +QGQ+YD A + +AQK++Q GV V+VGGSS PAVR Sbjct: 127 PTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDADRNWQIYANDQAKTAAEYAPLIV 246 +ELNP+AL G+ VR A++A N RP+G ++ A+ +WQ+ AND+ KTA Y PLIV Sbjct: 187 VELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIV 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSANGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG+PVR+QDVA V DSV DVRNAG + G+P+VL++I+R+PGANII TVD +R LP Sbjct: 247 HYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPA 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 L+ASIP++I + + DR+PTIRASL E E +L+++VALVI+VVF+FLR+ RATLIPAVAV Sbjct: 307 LRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRHIEAGMKPYQAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENISRH+EAG+KP AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPKVAALR 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMSISL+AVFIP+L+M G+ GRLFREFA+TLSVAI +SLV+SLT TPMMC Sbjct: 427 GVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMC 486 Query: 487 AQLLRHDPAADEARRQRRHPWLQKIADQSAAIFADMLLA----YERSLAWALRAAPLMMV 542 A LLR P + R + F +LLA Y RSL WAL +MV Sbjct: 487 AWLLRSHPKGQQQRIRG---------------FGKVLLAIQQGYGRSLNWALSHTRWVMV 531 Query: 543 ILVATIALNVHLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRAKLNEFIDIVKADPA 602 +L++TIALNV LY +IPK FFP+QDTGR++G I+ DQ+ISFQ+M+ KL +F+ IV ADPA Sbjct: 532 VLLSTIALNVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPA 591 Query: 603 VSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVVGRLRIKTAKVAGARVFLVPVQDIR 662 V V FTGG R N G M+++LKPLSER+++A +V+ RLR K AK GA +FL VQDIR Sbjct: 592 VDSVTGFTGGSRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIR 651 Query: 663 IGARQSDSEYEYSLKSDDVGLLRIWEPKIRLALTNLKELEDVSSDQQDNGLQTTLTIDRE 722 +G R S++ Y+++L +DD+ LR WEPK+R AL L +L DV+SDQQD G + LT DRE Sbjct: 652 VGGRHSNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRE 711 Query: 723 TAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPKYWQSPEILRDTYVSLA 782 T R G+ ++ L++ FGQRQISTIY +NQY VVME AP+Y Q L +V Sbjct: 712 TMARLGIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFV--- 768 Query: 783 GSSNLSPTTSSLSTPPALSASGQLNANTGLAQTLSTAPSKQVPLATFARFEPTTTSLAVN 842 +N+N + +PL+ FA+++P LAVN Sbjct: 769 -----------------------INSN-----------GQSIPLSYFAKWQPANAPLAVN 794 Query: 843 HDGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQSSTSSQPI 902 H G AST+SFNL +G SLS+ATAA++RAM +LGVP++V G FAGTA FQ + SQ Sbjct: 795 HQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGAFAGTAQVFQETLKSQLW 854 Query: 903 LILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMLTGTDFSLIALIGVILLI 962 LI+ A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL L FSLIALIG++LLI Sbjct: 855 LIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLI 914 Query: 963 GIVKKNAIMMVDFAIDAERHRGLSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGD 1022 GIVKKNAIMMVDFA+DA+R+ +S R+AIF+A LRFRPI+MTT+AAL GA+PL + GD Sbjct: 915 GIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMTTLAALFGALPLVLSSGD 974 Query: 1023 GAELRQPLGIAIVGGLVVSQLLTLYTTPVVYLYMERLSSWSKRRFGRK 1070 GAELRQPLGI IVGGLVVSQLLTLYTTPV+YLY +RL + RF ++ Sbjct: 975 GAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRL----RNRFSKQ 1018 >ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1025 Score = 1240 bits (3208), Expect = 0.0, Method: Compositional matrix adjust. Identities = 648/1070 (60%), Positives = 803/1070 (75%), Gaps = 60/1070 (5%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FI RP+AT LL++ I L GI+ FR+LPV+PLPQVD+P I +SAS+PGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD +RDI+GAARDVQAA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDADRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTA++ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSANGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG VR+ DVA V DSV DVRNAG N KP++L++I + P ANII TVD++R LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TL++SVALVI+VVFLFLR+ RAT+IPAVAV Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRHIEAGMKPYQAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENI+RH+EAGMKP QAAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMS+SL+AVF+P+L+M G+ GRL REFA+TLSVAI +SL+VSLT TPMMC Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 AQLLRHDPAADEARRQRRHPWLQKIADQSAAIFADMLLA----YERSLAWALRAAPLMMV 542 +L+ A + R Q+R F ML+A Y +SL W L L+ + Sbjct: 487 GWMLK----ASKPREQKRLRG-----------FGRMLVALQQGYGKSLKWVLNHTRLVGM 531 Query: 543 ILVATIALNVHLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRAKLNEFIDIVKADPA 602 +L+ TIALN+ LY +IPK FFP+QDTG L+GGI+ DQ+ISFQAMR KL +F+ I++ DPA Sbjct: 532 VLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPA 591 Query: 603 VSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVVGRLRIKTAKVAGARVFLVPVQDIR 662 V +V FTGG R N G M++TLKP ER ++A +++ RLR+K AK GA +FL+ VQDIR Sbjct: 592 VDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIR 651 Query: 663 IGARQSDSEYEYSLKSDDVGLLRIWEPKIRLALTNLKELEDVSSDQQDNGLQTTLTIDRE 722 +G RQS++ Y+Y+L SDD+ LR WEPKIR L L EL DV+SDQQDNG + L DR+ Sbjct: 652 VGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRD 711 Query: 723 TAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPKYWQSPEILRDTYVSLA 782 T R G+ Q +S L++ FGQRQISTIY MNQY VVME P+Y Q L +V Sbjct: 712 TMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFV--- 768 Query: 783 GSSNLSPTTSSLSTPPALSASGQLNANTGLAQTLSTAPSKQVPLATFARFEPTTTSLAVN 842 +N N G K +PL+ FA+++P L+VN Sbjct: 769 -----------------------IN-NEG----------KAIPLSYFAKWQPANAPLSVN 794 Query: 843 HDGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQSSTSSQPI 902 H G AST+SFNL G SLS A+AAIDRAM QLGVP++V G+FAGTA FQ + +SQ I Sbjct: 795 HQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVI 854 Query: 903 LILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMLTGTDFSLIALIGVILLI 962 LI+ A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL L FSLIALIG++LLI Sbjct: 855 LIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI 914 Query: 963 GIVKKNAIMMVDFAIDAERHRGLSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGD 1022 GIVKKNAIMMVDFA++A+RH L+P++AIF+AC LRFRPIMMTT+AAL GA+PL + GD Sbjct: 915 GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGD 974 Query: 1023 GAELRQPLGIAIVGGLVVSQLLTLYTTPVVYLYMERLSSWSKRRFGRKNK 1072 G+ELRQPLGI IVGGLV+SQLLTLYTTPVVYL+ +RL + RF RK+K Sbjct: 975 GSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL----RLRFSRKSK 1020 >yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1025 Score = 1238 bits (3204), Expect = 0.0, Method: Compositional matrix adjust. Identities = 649/1070 (60%), Positives = 802/1070 (74%), Gaps = 60/1070 (5%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FI RP+AT LL++ I L GI+ FR+LPV+PLPQVD+P I +SAS+PGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD +RDI+GAARDVQAA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDADRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTAV+ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSANGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG VR+ DVA V DSV DVRNAG N KP++L++I + P ANII TVD++R LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TL++SVALVI+VVFLFLR+ RAT+IPAV+V Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRHIEAGMKPYQAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENI+RH+EAGMKP QAAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMS+SL+AVF+P+L+M G+ GRL REFA+TLSVAI +SL+VSLT TPMMC Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 AQLLRHDPAADEARRQRRHPWLQKIADQSAAIFADMLLA----YERSLAWALRAAPLMMV 542 +L+ A + R Q+R F ML+A Y +SL W L L+ V Sbjct: 487 GWMLK----ASKPREQKRLRG-----------FGRMLVALQQGYGKSLKWVLNHTRLVGV 531 Query: 543 ILVATIALNVHLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRAKLNEFIDIVKADPA 602 +L+ TIALN+ LY +IPK FFP+QDTG L+GGI+ DQ+ISFQAMR KL +F+ I++ DPA Sbjct: 532 VLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPA 591 Query: 603 VSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVVGRLRIKTAKVAGARVFLVPVQDIR 662 V +V FTGG R N G M++TLKP ER ++A +++ RLR+K AK GA +FL+ VQDIR Sbjct: 592 VDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIR 651 Query: 663 IGARQSDSEYEYSLKSDDVGLLRIWEPKIRLALTNLKELEDVSSDQQDNGLQTTLTIDRE 722 +G RQS++ Y+Y+L SDD+ LR WEPKIR L L EL DV+SDQQDNG + L DR+ Sbjct: 652 VGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRD 711 Query: 723 TAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPKYWQSPEILRDTYVSLA 782 T R G+ Q +S L++ FGQRQISTIY MNQY VVME P+Y Q L +V Sbjct: 712 TMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFV--- 768 Query: 783 GSSNLSPTTSSLSTPPALSASGQLNANTGLAQTLSTAPSKQVPLATFARFEPTTTSLAVN 842 +N N G K +PL+ FA+++P L+VN Sbjct: 769 -----------------------IN-NEG----------KAIPLSYFAKWQPANAPLSVN 794 Query: 843 HDGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQSSTSSQPI 902 H G AST+SFNL G SLS A+AAIDRAM QLGVP++V G+FAGTA FQ + +SQ I Sbjct: 795 HQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVI 854 Query: 903 LILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMLTGTDFSLIALIGVILLI 962 LI+ A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL L FSLIALIG++LLI Sbjct: 855 LIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI 914 Query: 963 GIVKKNAIMMVDFAIDAERHRGLSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGD 1022 GIVKKNAIMMVDFA++A+RH L+P++AIF+AC LRFRPIMMTT+AAL GA+PL + GD Sbjct: 915 GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGD 974 Query: 1023 GAELRQPLGIAIVGGLVVSQLLTLYTTPVVYLYMERLSSWSKRRFGRKNK 1072 G+ELRQPLGI IVGGLV+SQLLTLYTTPVVYL+ +RL + RF RK K Sbjct: 975 GSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL----RLRFSRKPK 1020 >ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1025 Score = 1234 bits (3192), Expect = 0.0, Method: Compositional matrix adjust. Identities = 646/1070 (60%), Positives = 800/1070 (74%), Gaps = 60/1070 (5%) Query: 7 FIQRPIATTLLTIGIALAGIVAFRLLPVSPLPQVDYPTISISASMPGASPETMAATVATP 66 FI RP+AT LL++ I L GI+ FR+LPV+PLPQVD+P I +SAS+PGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD RDI+ AARDV AA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFXRDINXAARDVXAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDADRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTA++ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSANGKPSVLIIINRQPGANIIDTVDNVRELLPQ 306 Y NG VR+ DVA V DSV DVRNAG N KP++L++I + P ANII TVD++R LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TL++SVALVI+VVFLFLR+ RAT+IPAVAV Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRHIEAGMKPYQAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENI+RH+EAGMKP QAAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMS+SL+AVF+P+L+M G+ GRL REFA+TLSVAI +SL+VSLT TPMMC Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 AQLLRHDPAADEARRQRRHPWLQKIADQSAAIFADMLLA----YERSLAWALRAAPLMMV 542 +L+ A + R Q+R F ML+A Y +SL W L L+ + Sbjct: 487 GWMLK----ASKPREQKRLRG-----------FGRMLVALQQGYGKSLKWVLNHTRLVGM 531 Query: 543 ILVATIALNVHLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRAKLNEFIDIVKADPA 602 +L+ TIALN+ LY +IPK FFP+QDTG L+GGI+ DQ+ISFQAMR KL +F+ I++ DPA Sbjct: 532 VLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPA 591 Query: 603 VSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKVVGRLRIKTAKVAGARVFLVPVQDIR 662 V +V FTGG R N G M++TLKP ER ++A +++ RLR+K AK GA +FL+ VQDIR Sbjct: 592 VDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIR 651 Query: 663 IGARQSDSEYEYSLKSDDVGLLRIWEPKIRLALTNLKELEDVSSDQQDNGLQTTLTIDRE 722 +G RQS++ Y+Y+L SDD+ LR WEPKIR L L EL DV+SDQQDNG + L DR+ Sbjct: 652 VGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRD 711 Query: 723 TAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPKYWQSPEILRDTYVSLA 782 T R G+ Q +S L++ FGQRQISTIY MNQY VVME P+Y Q L +V Sbjct: 712 TMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFV--- 768 Query: 783 GSSNLSPTTSSLSTPPALSASGQLNANTGLAQTLSTAPSKQVPLATFARFEPTTTSLAVN 842 +N N G K +PL+ FA+++P L+VN Sbjct: 769 -----------------------IN-NEG----------KAIPLSYFAKWQPANAPLSVN 794 Query: 843 HDGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQSSTSSQPI 902 H G AST+SFNL G SLS A+AAIDRAM QLGVP++V G+FAGTA FQ + +SQ I Sbjct: 795 HQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVI 854 Query: 903 LILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMLTGTDFSLIALIGVILLI 962 LI+ A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL L FSLIALIG++LLI Sbjct: 855 LIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI 914 Query: 963 GIVKKNAIMMVDFAIDAERHRGLSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGD 1022 GIVKKNAIMMVDFA++A+RH L+P++AIF+AC LRFRPIMMTT+AAL GA+PL + GD Sbjct: 915 GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGD 974 Query: 1023 GAELRQPLGIAIVGGLVVSQLLTLYTTPVVYLYMERLSSWSKRRFGRKNK 1072 G+ELRQPLGI IVGGLV+SQLLTLYTTPVVYL+ +RL + RF RK+K Sbjct: 975 GSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL----RLRFSRKSK 1020