BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1361.p (1035 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1605 0.0 PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas ... 1452 0.0 YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1424 0.0 yegN [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1382 0.0 ZyegN [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1381 0.0 >RSp1198 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1041 Score = 1605 bits (4156), Expect = 0.0, Method: Compositional matrix adjust. Identities = 800/1030 (77%), Positives = 920/1030 (89%), Gaps = 1/1030 (0%) Query: 1 MNPSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMT 60 MNPSR FILRPVAT+LLM+AILL G+VAYR+LPLSALPEVDYPTIQV TLYPGASPDVMT Sbjct: 1 MNPSRIFILRPVATTLLMVAILLSGLVAYRMLPLSALPEVDYPTIQVTTLYPGASPDVMT 60 Query: 61 SSVTAPLERQFGQMPGLKQMASTSSGGASVITLQFNLDLSLDVAEQEVQAAINAGSNLLP 120 SS+TAPLERQFGQMPGLKQM S SSGGASVITLQF+L LSLD+AEQEVQAAINA NLLP Sbjct: 61 SSITAPLERQFGQMPGLKQMTSASSGGASVITLQFDLSLSLDIAEQEVQAAINAAGNLLP 120 Query: 121 SDLPMPPVYSKVNPADTPIITLAVTSKTMPLPKVQDLIDTRLAQKISQLSGVGLVSLSGG 180 +DLPMPP+YSKVNPAD PI+TLA+TS+T+PLPK++D++DTR+AQK+SQL G+GLVS+SGG Sbjct: 121 TDLPMPPIYSKVNPADAPILTLAITSRTLPLPKLEDIVDTRVAQKLSQLPGIGLVSISGG 180 Query: 181 QRPAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADE 240 QRPAVR+Q N +A+AALGL++DD+RTAIGNANVN AKGSFDGP RASTIDANDQLRSA E Sbjct: 181 QRPAVRIQANTQALAALGLSIDDIRTAIGNANVNGAKGSFDGPMRASTIDANDQLRSAAE 240 Query: 241 YRKLIIAYKNGAPIRVSDVADVIDGAENVRLGAWANQQPAVIVNIQRQPGANVIAVVDSI 300 Y +I+AYKNGAPIR++DVA +IDGAEN +L AWAN PA+I+N+QRQPGANVI VV+ Sbjct: 241 YGTMIVAYKNGAPIRLTDVAQIIDGAENSKLAAWANTTPAIILNVQRQPGANVIDVVNRA 300 Query: 301 KKILPQLQANLPGSIDVHILTDRTTTIRASVADVKFELLLSVALVVMVIFVFLRNVPATI 360 K +LPQL+ LP +IDV +LTDRTTTIRASVADV+FELLL+VALVVMVIF+FLRN+PATI Sbjct: 301 KALLPQLKDTLPANIDVAVLTDRTTTIRASVADVQFELLLAVALVVMVIFLFLRNIPATI 360 Query: 361 IPSVAVPLSLVGTFAVMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKP 420 IP+VAVPLSLVGTF VMYLAGFS+NNLTLMALTIATGFVVDDAIVMIENI+RYIE+G P Sbjct: 361 IPAVAVPLSLVGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMIENIARYIEDGDPP 420 Query: 421 MQAALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLT 480 M+AALKGA QIGFTIISLTFSLIAVLIPLLFM DVVGRLF EFA+TLAVSILISAVVSLT Sbjct: 421 MEAALKGARQIGFTIISLTFSLIAVLIPLLFMSDVVGRLFREFAITLAVSILISAVVSLT 480 Query: 481 LTPMMCARLLRHQPEEQQGWFYHQSQAFFDRIIARYGVMLQWVLQRQKMTLLVAVATLGL 540 LTPMMCARLLRH PE +Q FYH + FFD +IA+YG MLQWVL RQ+ TLLVA+ TL L Sbjct: 481 LTPMMCARLLRHIPEPEQTRFYHAAGQFFDNVIAQYGRMLQWVLDRQRTTLLVAIGTLAL 540 Query: 541 TALLYVFVPKGFFPLQDTGVIQGISEASQSISFGAMGAKQQELAKVVLEDPAVDSLSSFI 600 T LLYV+VPKGFFP+QDTGVIQGIS+A+QSISF AM +QQ+LA+V+L+DPAV+SLSSFI Sbjct: 541 TGLLYVYVPKGFFPVQDTGVIQGISDATQSISFPAMAERQQKLAEVILKDPAVESLSSFI 600 Query: 601 GVDGTNATLNSGRMLINLKPHEERDVSASDVIRRLQPKLAQQVPGVTLYMQPVQDLTIED 660 GVDGTN TLNSGRMLINLKP + RD A+++I+RLQP+LA +V G++L+MQPVQDLTIED Sbjct: 601 GVDGTNTTLNSGRMLINLKPKDARDADATEIIQRLQPELA-KVGGISLFMQPVQDLTIED 659 Query: 661 SVSRTQYQFTLEDADAGTLSSWVPKLIARLQQVPQLADVASNLQDQGLQAYIEIDRNAAS 720 VSRTQYQFT+ED D LS WVP+L+ RLQQ +L DVAS+LQD GL+AY++IDR+ A+ Sbjct: 660 RVSRTQYQFTVEDPDPNNLSKWVPRLVERLQQTGELRDVASDLQDNGLRAYVQIDRDKAA 719 Query: 721 RLGITTAAIDNALYNAFGQRLISTIYTQSNLYRVVMEVKPEFQHGPQALDSIFLVTSAGG 780 G+TTAA+D+ALY+A+GQRLISTI+TQSN YRVV+E P+ Q GPQ+L + + ++ G Sbjct: 720 VYGVTTAAVDSALYSAYGQRLISTIFTQSNQYRVVLEAAPQLQKGPQSLYDLRVASTGGQ 779 Query: 781 KVPLSSIATVTERTAPLVVNHIGQFPAATISFNLAKGASLGEAVKAIKAAEEEIGMPSST 840 +VPL + ATV E+ LVVNH GQFP+ATISFNLA+GASLG AV AI AAE+ IG+P+S Sbjct: 780 QVPLGAFATVVEQPGSLVVNHQGQFPSATISFNLARGASLGAAVDAINAAEQAIGLPASM 839 Query: 841 VTNFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLS 900 T+FQGAALAFQ+SLSN LWLILAAI+TMYIVLGVLYES IHP+TILSTLPSAGVGALLS Sbjct: 840 QTSFQGAALAFQSSLSNELWLILAAIITMYIVLGVLYESTIHPVTILSTLPSAGVGALLS 899 Query: 901 LMISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHQGKSPQEAIYQACLLRFRPI 960 L++SG D+GII IIGIILLIGIVKKNAIMMIDFALEAER QG +P++AIYQACLLRFRPI Sbjct: 900 LLVSGKDMGIIAIIGIILLIGIVKKNAIMMIDFALEAEREQGMAPRDAIYQACLLRFRPI 959 Query: 961 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRR 1020 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYL FDSLG R Sbjct: 960 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLAFDSLGHR 1019 Query: 1021 LRARFGRKAS 1030 LR R+A+ Sbjct: 1020 LRDWRERRAA 1029 >PA2527 [V] COG0841 Cation/multidrug efflux pump Pae Pseudomonas aeruginosa Length = 1043 Score = 1452 bits (3760), Expect = 0.0, Method: Compositional matrix adjust. Identities = 751/1023 (73%), Positives = 890/1023 (86%), Gaps = 1/1023 (0%) Query: 1 MNPSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMT 60 MNPSR FILRPVAT+LLM+AILL G++AYR LP+SALPEVDYPTIQVVTLYPGASP++MT Sbjct: 1 MNPSRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMT 60 Query: 61 SSVTAPLERQFGQMPGLKQMASTSSGGASVITLQFNLDLSLDVAEQEVQAAINAGSNLLP 120 SS+TAPLE Q GQ+PGL +M+S+SSGGASVITLQF+L +LDVAEQEVQAAINA +LLP Sbjct: 61 SSITAPLENQLGQIPGLNEMSSSSSGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLP 120 Query: 121 SDLPMPPVYSKVNPADTPIITLAVTSKTMPLPKVQDLIDTRLAQKISQLSGVGLVSLSGG 180 +DLP PV+SKVNPAD PI+TLAV S MPLP++QDL+DTRLAQKISQ+SGVGLVS+SGG Sbjct: 121 NDLPNQPVFSKVNPADAPILTLAVMSDGMPLPQIQDLVDTRLAQKISQISGVGLVSISGG 180 Query: 181 QRPAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADE 240 QRPAVR++ NP A+AA GL+L+D+R+ + + N+N KGSFDGPTRAST+DANDQLRSAD Sbjct: 181 QRPAVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRASTLDANDQLRSADA 240 Query: 241 YRKLIIAYKNGAPIRVSDVADVIDGAENVRLGAWANQQPAVIVNIQRQPGANVIAVVDSI 300 YR LIIAYKNG+P+R+ DVA V D AENVRL AWAN PAV++NIQRQPGANVI VVD I Sbjct: 241 YRDLIIAYKNGSPLRIRDVASVEDDAENVRLAAWANNLPAVVLNIQRQPGANVIEVVDRI 300 Query: 301 KKILPQLQANLPGSIDVHILTDRTTTIRASVADVKFELLLSVALVVMVIFVFLRNVPATI 360 K +LPQLQ+ LPG++DV +LTDRTTTIRASV DV+FEL L+VALVVMV F+FLRNV AT+ Sbjct: 301 KALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFLFLRNVYATL 360 Query: 361 IPSVAVPLSLVGTFAVMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKP 420 IPS AVPLSL+GTF VMYL+GFSINNLTLMALTIATGFVVDDAIVM+ENI+RY+E+G P Sbjct: 361 IPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIARYLEQGDSP 420 Query: 421 MQAALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLT 480 ++AALKG++QIGFTIISLTFSLIAVLIPLLFMGDV GRLF EFA+TLAV+ILIS VSLT Sbjct: 421 LEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAILISGFVSLT 480 Query: 481 LTPMMCARLLRHQPEEQQGWFYHQSQAFFDRIIARYGVMLQWVLQRQKMTLLVAVATLGL 540 LTPM+ A+LLRH E+QQG F + D +IA+Y L+ VL+ Q +TLLVA+ATL L Sbjct: 481 LTPMLSAKLLRHIDEDQQGRFARAAGRVIDGLIAQYAKALRVVLRHQPLTLLVAIATLAL 540 Query: 541 TALLYVFVPKGFFPLQDTGVIQGISEASQSISFGAMGAKQQELAKVVLEDPAVDSLSSFI 600 TALLY+ +PKGFFP+QDTGVIQG++EA QSISF AM +Q+ LA+VVL+DPAV SLSS+I Sbjct: 541 TALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLKDPAVASLSSYI 600 Query: 601 GVDGTNATLNSGRMLINLKPHEERDVSASDVIRRLQPKLAQQVPGVTLYMQPVQDLTIED 660 GVDG+N TLN+GR+LINLKPH ERDV+AS+VI+RLQP+L +PG+ LYMQPVQDLTIED Sbjct: 601 GVDGSNPTLNTGRLLINLKPHSERDVTASEVIQRLQPEL-DHLPGIKLYMQPVQDLTIED 659 Query: 661 SVSRTQYQFTLEDADAGTLSSWVPKLIARLQQVPQLADVASNLQDQGLQAYIEIDRNAAS 720 V+RTQYQFTL+DAD L+ WVPKL+ARLQ++PQLADVAS+ QD+GLQAY+ IDR+ AS Sbjct: 660 RVARTQYQFTLQDADPDVLAEWVPKLVARLQELPQLADVASDWQDKGLQAYLNIDRDTAS 719 Query: 721 RLGITTAAIDNALYNAFGQRLISTIYTQSNLYRVVMEVKPEFQHGPQALDSIFLVTSAGG 780 RLG+ + ID+ LYNAFGQRLISTI+TQ+ YRVV+EV P+FQ GPQAL+ +++ +S G Sbjct: 720 RLGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQFQLGPQALEQLYVPSSDGT 779 Query: 781 KVPLSSIATVTERTAPLVVNHIGQFPAATISFNLAKGASLGEAVKAIKAAEEEIGMPSST 840 +V LSS+A V ER L +NHI QFP+AT+SFNLAKG SLGEAV+AI+ E + +P S Sbjct: 780 QVRLSSLAKVEERHTLLAINHIAQFPSATLSFNLAKGYSLGEAVEAIRGVEASLELPLSM 839 Query: 841 VTNFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLS 900 +F+GAALAF+ASLSNTL LILA++VTMYIVLG+LYES+IHP+TILSTLPSAGVGALL+ Sbjct: 840 QGSFRGAALAFEASLSNTLLLILASVVTMYIVLGILYESFIHPVTILSTLPSAGVGALLA 899 Query: 901 LMISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHQGKSPQEAIYQACLLRFRPI 960 LM++G ++GI+ IIGIILLIGIVKKNAIMMIDFAL+AER++GK P EAIYQACLLRFRPI Sbjct: 900 LMLAGQEIGIVAIIGIILLIGIVKKNAIMMIDFALDAERNEGKPPHEAIYQACLLRFRPI 959 Query: 961 LMTTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRR 1020 LMTTMAALLGALPLML G G+ELRQPLGITMVGGLL+SQVLTLFTTPVIYL FD L RR Sbjct: 960 LMTTMAALLGALPLMLAGGAGAELRQPLGITMVGGLLLSQVLTLFTTPVIYLYFDRLARR 1019 Query: 1021 LRA 1023 A Sbjct: 1020 WAA 1022 >YPO2848 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1052 Score = 1424 bits (3686), Expect = 0.0, Method: Compositional matrix adjust. Identities = 720/1022 (70%), Positives = 851/1022 (83%), Gaps = 1/1022 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FILRPVAT+L M+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDV+TSS Sbjct: 12 PSRLFILRPVATTLFMIAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVVTSS 71 Query: 63 VTAPLERQFGQMPGLKQMASTSSGGASVITLQFNLDLSLDVAEQEVQAAINAGSNLLPSD 122 +TAPLERQFGQM GLKQMAS SSGGASVITLQF L L LDVAEQEVQAAINA +NLLPSD Sbjct: 72 ITAPLERQFGQMSGLKQMASQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSKTMPLPKVQDLIDTRLAQKISQLSGVGLVSLSGGQR 182 LP PP+Y+KVNPAD PI+TLAVT+ +P+ +V+D+++TR+AQKISQ++GVGLV+LSGGQR Sbjct: 132 LPYPPIYNKVNPADPPILTLAVTATAIPMTQVEDMVETRIAQKISQVTGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN AVAALGL+ + +RTAI NANVN AKGS DGPTR+ T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAPAVAALGLDSETIRTAISNANVNSAKGSLDGPTRSVTLSANDQMKSAEEYR 251 Query: 243 KLIIAYKNGAPIRVSDVADVIDGAENVRLGAWANQQPAVIVNIQRQPGANVIAVVDSIKK 302 LIIAY+NGAPIR+ DVA + GAEN +L AWAN Q A+++NIQRQPG NVIA DSI++ Sbjct: 252 DLIIAYQNGAPIRLQDVATIEQGAENNKLAAWANTQSAIVLNIQRQPGVNVIATADSIRE 311 Query: 303 ILPQLQANLPGSIDVHILTDRTTTIRASVADVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LP+L +LP S+DV +LTDRT+TIRASV DV+FELLL++ALVVMVI++FLRN ATIIP Sbjct: 312 MLPELIKSLPKSVDVKVLTDRTSTIRASVNDVQFELLLAIALVVMVIYLFLRNAAATIIP 371 Query: 363 SVAVPLSLVGTFAVMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 S+AVPLSLVGTFA MY GFSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 SIAVPLSLVGTFAAMYFLGFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLD 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFM D+VGRLF EFAVTLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMEDIVGRLFREFAVTLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHQSQAFFDRIIARYGVMLQWVLQRQKMTLLVAVATLGLTA 542 PMMCAR+L ++ +Q S+ FFD +IA Y V L+ VL +TL VA +TL LT Sbjct: 492 PMMCARMLSYESLRKQNRLSRASEKFFDWVIAHYAVALKKVLNHPWLTLSVAFSTLVLTV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEASQSISFGAMGAKQQELAKVVLEDPAVDSLSSFIGV 602 +LY+ +PKGFFPLQD G+IQG EA QS+SF M +QQ++A ++L+DPAV+SL+SF+GV Sbjct: 552 ILYLLIPKGFFPLQDNGLIQGTLEAPQSVSFSNMAERQQQVAAIILKDPAVESLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEERDVSASDVIRRLQPKLAQQVPGVTLYMQPVQDLTIEDSV 662 DGTNATLN+GR+ INLKP ERD +I RLQ ++ VPG+ LY+QPVQDLTI+ + Sbjct: 612 DGTNATLNNGRLQINLKPLSERDDRIPQIITRLQESVS-GVPGIKLYLQPVQDLTIDTQL 670 Query: 663 SRTQYQFTLEDADAGTLSSWVPKLIARLQQVPQLADVASNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LS+WVPKL+ LQQ DV S+ QDQGL A++ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLEELSTWVPKLVNELQQKAPFQDVTSDWQDQGLVAFVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNLYRVVMEVKPEFQHGPQALDSIFLVTSAGGKV 782 GIT AAIDNALYNAFGQRLISTIYTQSN YRVV+E + G A + I L G V Sbjct: 731 GITMAAIDNALYNAFGQRLISTIYTQSNQYRVVLEHDVQATPGLAAFNDIRLTGIDGKGV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATISFNLAKGASLGEAVKAIKAAEEEIGMPSSTVT 842 PLSSIAT+ ER PL +NH+ QFP+AT+SFNLA+G SLGEAV A+ AE+EI +P+ T Sbjct: 791 PLSSIATIEERFGPLSINHLNQFPSATVSFNLAQGYSLGEAVAAVTLAEKEIQLPADITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQA+L +TLWLI+AAIV MYIVLGVLYES+IHPITILSTLP+AGVGALL+LM Sbjct: 851 RFQGSTLAFQAALGSTLWLIIAAIVAMYIVLGVLYESFIHPITILSTLPTAGVGALLALM 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHQGKSPQEAIYQACLLRFRPILM 962 ++G +L +I IIGIILLIGIVKKNAIMMIDFAL AER QG +P +AIYQACLLRFRPILM Sbjct: 911 LTGNELDVIAIIGIILLIGIVKKNAIMMIDFALAAERDQGMTPYDAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AAL GALPLML TGVG+ELRQPLG+ MVGGL+VSQVLTLFTTPVIYL FD L R R Sbjct: 971 TTLAALFGALPLMLSTGVGAELRQPLGVCMVGGLIVSQVLTLFTTPVIYLLFDKLARNTR 1030 Query: 1023 AR 1024 + Sbjct: 1031 GK 1032 >yegN [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1040 Score = 1382 bits (3577), Expect = 0.0, Method: Compositional matrix adjust. Identities = 713/1026 (69%), Positives = 858/1026 (83%), Gaps = 1/1026 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FI+RPVAT+LLM+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDVMTS+ Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQFGQMPGLKQMASTSSGGASVITLQFNLDLSLDVAEQEVQAAINAGSNLLPSD 122 VTAPLERQFGQM GLKQM+S SSGGASVITLQF L L LDVAEQEVQAAINA +NLLPSD Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSKTMPLPKVQDLIDTRLAQKISQLSGVGLVSLSGGQR 182 LP PPVYSKVNPAD PI+TLAVTS MP+ +V+D+++TR+AQKISQ+SGVGLV+LSGGQR Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN +A+AALGL + VRTAI ANVN AKGS DGP+RA T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 KLIIAYKNGAPIRVSDVADVIDGAENVRLGAWANQQPAVIVNIQRQPGANVIAVVDSIKK 302 +LIIAY+NGAPIR+ DVA V GAEN LGAWAN++ A+++N+QRQPGAN+I+ DSI++ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 ILPQLQANLPGSIDVHILTDRTTTIRASVADVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LPQL +LP S+ V +L+DRTT IRASV D +FEL++++ALVVM+I++FLRN+PATIIP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFAVMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 VAVPLSL+GTFAVM FSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFMGD+VGRLF EFA+TLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHQSQAFFDRIIARYGVMLQWVLQRQKMTLLVAVATLGLTA 542 PMMCAR+L + +Q F S+ FDRIIA YG L VL +TL VA++TL L+ Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEASQSISFGAMGAKQQELAKVVLEDPAVDSLSSFIGV 602 LL+VF+PKGFFP+QD G+IQG +A QS SF M +Q+++A V+L+DPAV SL+SF+GV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEERDVSASDVIRRLQPKLAQQVPGVTLYMQPVQDLTIEDSV 662 DGTN +LNS R+ INLKP +ERD VI RLQ + +VPGV L++QP QDLTI+ V Sbjct: 612 DGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAV-DKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 SRTQYQFTLEDADAGTLSSWVPKLIARLQQVPQLADVASNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LS+WVP+L+ +LQQ+PQL+DV+S+ QD+GL AY+ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNLYRVVMEVKPEFQHGPQALDSIFLVTSAGGKV 782 GI+ A +DNALYNAFGQRLISTIYTQ+N YRVV+E E G ALD+I L +S GG V Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATISFNLAKGASLGEAVKAIKAAEEEIGMPSSTVT 842 PLSSIA + +R APL +NH+ QFP TISFN+ SLG+AV+AI E+ + +P T Sbjct: 791 PLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQ++L +T+WLI+AA+V MYIVLG+LYES+IHPITILSTLP+AGVGALL+L+ Sbjct: 851 QFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALL 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHQGKSPQEAIYQACLLRFRPILM 962 I+G++L +I IIGIILLIGIVKKNAIMMIDFAL AER QG SP+EAIYQACLLRFRPILM Sbjct: 911 IAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AALLGALPLML TGVG+ELR+PLGI MVGGL+VSQVLTLFTTPVIYL FD L + Sbjct: 971 TTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK 1030 Query: 1023 ARFGRK 1028 +RF R Sbjct: 1031 SRFARH 1036 >ZyegN [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1040 Score = 1381 bits (3575), Expect = 0.0, Method: Compositional matrix adjust. Identities = 712/1026 (69%), Positives = 858/1026 (83%), Gaps = 1/1026 (0%) Query: 3 PSRQFILRPVATSLLMLAILLVGIVAYRLLPLSALPEVDYPTIQVVTLYPGASPDVMTSS 62 PSR FI+RPVAT+LLM+AILL GI+ YR LP+SALPEVDYPTIQVVTLYPGASPDVMTS+ Sbjct: 12 PSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSA 71 Query: 63 VTAPLERQFGQMPGLKQMASTSSGGASVITLQFNLDLSLDVAEQEVQAAINAGSNLLPSD 122 VTAPLERQFGQM GLKQM+S SSGGASVITLQF L L LDVAEQEVQAAINA +NLLPSD Sbjct: 72 VTAPLERQFGQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 Query: 123 LPMPPVYSKVNPADTPIITLAVTSKTMPLPKVQDLIDTRLAQKISQLSGVGLVSLSGGQR 182 LP PPVYSKVNPAD PI+TLAVTS MP+ +V+D+++TR+AQKISQ+SGVGLV+LSGGQR Sbjct: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVEDMVETRVAQKISQISGVGLVTLSGGQR 191 Query: 183 PAVRMQLNPRAVAALGLNLDDVRTAIGNANVNQAKGSFDGPTRASTIDANDQLRSADEYR 242 PAVR++LN +A+AALGL + VRTAI ANVN AKGS DGP+RA T+ ANDQ++SA+EYR Sbjct: 192 PAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSANDQMQSAEEYR 251 Query: 243 KLIIAYKNGAPIRVSDVADVIDGAENVRLGAWANQQPAVIVNIQRQPGANVIAVVDSIKK 302 +LIIAY+NGAPIR+ DVA V GAEN LGAWAN++ A+++N+QRQPGAN+I+ DSI++ Sbjct: 252 QLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQ 311 Query: 303 ILPQLQANLPGSIDVHILTDRTTTIRASVADVKFELLLSVALVVMVIFVFLRNVPATIIP 362 +LPQL +LP S+ V +L+DRTT IRASV D +FEL++++ALVVM+I++FLRN+PATIIP Sbjct: 312 MLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIP 371 Query: 363 SVAVPLSLVGTFAVMYLAGFSINNLTLMALTIATGFVVDDAIVMIENISRYIEEGMKPMQ 422 VAVPLSL+GTFAVM FSINNLTLMALTIATGFVVDDAIV+IENISRYIE+G KP+ Sbjct: 372 GVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLA 431 Query: 423 AALKGAEQIGFTIISLTFSLIAVLIPLLFMGDVVGRLFHEFAVTLAVSILISAVVSLTLT 482 AALKGA +IGFTIISLTFSLIAVLIPLLFMGD+VGRLF EFA+TLAV+ILISAVVSLTLT Sbjct: 432 AALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLT 491 Query: 483 PMMCARLLRHQPEEQQGWFYHQSQAFFDRIIARYGVMLQWVLQRQKMTLLVAVATLGLTA 542 PMMCAR+L + +Q F S+ FDRIIA YG L VL +TL VA++TL L+ Sbjct: 492 PMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSV 551 Query: 543 LLYVFVPKGFFPLQDTGVIQGISEASQSISFGAMGAKQQELAKVVLEDPAVDSLSSFIGV 602 LL+VF+PKGFFP+QD G+IQG +A QS SF M +Q+++A V+L+DPAV SL+SF+GV Sbjct: 552 LLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGV 611 Query: 603 DGTNATLNSGRMLINLKPHEERDVSASDVIRRLQPKLAQQVPGVTLYMQPVQDLTIEDSV 662 DGTN +LNS R+ INLKP +ERD VI RLQ + +VPGV L++QP QDLTI+ V Sbjct: 612 DGTNPSLNSARLQINLKPLDERDDRVQKVIARLQTAV-DKVPGVDLFLQPTQDLTIDTQV 670 Query: 663 SRTQYQFTLEDADAGTLSSWVPKLIARLQQVPQLADVASNLQDQGLQAYIEIDRNAASRL 722 SRTQYQFTL+ LS+WVP+L+ +LQQ+PQ++DV+S+ QD+GL AY+ +DR++ASRL Sbjct: 671 SRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQISDVSSDWQDKGLVAYVNVDRDSASRL 730 Query: 723 GITTAAIDNALYNAFGQRLISTIYTQSNLYRVVMEVKPEFQHGPQALDSIFLVTSAGGKV 782 GI+ A +DNALYNAFGQRLISTIYTQ+N YRVV+E E G ALD+I L +S GG V Sbjct: 731 GISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVV 790 Query: 783 PLSSIATVTERTAPLVVNHIGQFPAATISFNLAKGASLGEAVKAIKAAEEEIGMPSSTVT 842 PLSSIA + +R APL +NH+ QFP TISFN+ SLG+AV+AI E+ + +P T Sbjct: 791 PLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITT 850 Query: 843 NFQGAALAFQASLSNTLWLILAAIVTMYIVLGVLYESYIHPITILSTLPSAGVGALLSLM 902 FQG+ LAFQ++L +T+WLI+AA+V MYIVLG+LYES+IHPITILSTLP+AGVGALL+LM Sbjct: 851 QFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALM 910 Query: 903 ISGTDLGIIGIIGIILLIGIVKKNAIMMIDFALEAERHQGKSPQEAIYQACLLRFRPILM 962 I+G++L +I IIGIILLIGIVKKNAIMMIDFAL AER QG SP++AIYQACLLRFRPILM Sbjct: 911 IAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQACLLRFRPILM 970 Query: 963 TTMAALLGALPLMLGTGVGSELRQPLGITMVGGLLVSQVLTLFTTPVIYLGFDSLGRRLR 1022 TT+AALLGALPLML TGVG+ELR+PLGI MVGGL+VSQVLTLFTTPVIYL FD L + Sbjct: 971 TTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK 1030 Query: 1023 ARFGRK 1028 +RF R Sbjct: 1031 SRFARH 1036