BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1293.p (272 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA3508 [K] COG1414 Transcriptional regulator Pae Pseudomonas aer... 371 e-102 BMEII0642 [K] COG1414 Transcriptional regulator Bme Brucella mel... 114 2e-25 PA0155 [K] COG1414 Transcriptional regulator Pae Pseudomonas aer... 113 5e-25 yagI [K] COG1414 Transcriptional regulator Eco Escherichia coli K12 111 2e-24 Cgl2340 [K] COG1414 Transcriptional regulator Cgl Corynebacteriu... 108 1e-23 >PA3508 [K] COG1414 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 277 Score = 371 bits (952), Expect = e-102, Method: Compositional matrix adjust. Identities = 187/268 (69%), Positives = 222/268 (82%), Gaps = 2/268 (0%) Query: 4 EESQDKYSVPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVER 63 ++SQDKY VPGLERGL LLCEFSR+D+TL+APELARRL +PRST+FRLL TLE MGFV R Sbjct: 5 DDSQDKYIVPGLERGLLLLCEFSRKDRTLTAPELARRLKLPRSTIFRLLTTLEAMGFVTR 64 Query: 64 ADGGRDYRLGMSVLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAK 123 G +YRLGM+VLRLGFEYLASLELTE+G+PLL+RL DEI Y CNLVVRDGRSIVYVAK Sbjct: 65 --NGNEYRLGMAVLRLGFEYLASLELTELGQPLLNRLCDEIRYPCNLVVRDGRSIVYVAK 122 Query: 124 SVTQTAFTSHVNVGTRLPAHATVLGRVLLEDLSLPQLRALYPEQHLEVFSSNTPKTVVEL 183 T +S VNVGTRLPAHATVLGR+LL+DLSL +LR LYPE+ LE FS NTP++V+EL Sbjct: 123 VSPSTPLSSSVNVGTRLPAHATVLGRILLQDLSLGELRELYPEEQLEQFSPNTPRSVLEL 182 Query: 184 FDMVQADKERGFVLQEGFFETSISTVAAPVRDHSGLVVAALGATIPSPHIDASQLDVIVA 243 FDMVQ D++RGFV EGFFE SISTVAAPVRDHSG V+AA+GATI + HID +++ +V+ Sbjct: 183 FDMVQGDRQRGFVQGEGFFEASISTVAAPVRDHSGRVIAAMGATIAAGHIDPERIEGLVS 242 Query: 244 RVRETAAELSRLLDHAPERGAKVVNMWR 271 RVR +A ELS LLD+ + V ++R Sbjct: 243 RVRSSADELSYLLDYRADGQDNVTPIFR 270 >BMEII0642 [K] COG1414 Transcriptional regulator Bme Brucella melitensis Length = 256 Score = 114 bits (286), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 73/227 (32%), Positives = 118/227 (51%), Gaps = 2/227 (0%) Query: 12 VPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVERADGGRDYR 71 V G +GLR++ F LS ++++ + R+T R L TL +G+ E G+ + Sbjct: 7 VGGFAKGLRVIEAFGEDRPRLSIADVSKITGLDRATARRCLLTLAELGYAEY--DGKFFM 64 Query: 72 LGMSVLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAKSVTQTAFT 131 L +LRLG YL+ L I +P LDRL +G S + V DG IVY+A++ + Sbjct: 65 LLPRILRLGHAYLSGTPLPTIIQPHLDRLSQSVGESASASVLDGAEIVYIARASQMRVIS 124 Query: 132 SHVNVGTRLPAHATVLGRVLLEDLSLPQLRALYPEQHLEVFSSNTPKTVVELFDMVQADK 191 ++ G+RLPA+ +GRVLL L + R + + L + T K +L + ++ + Sbjct: 125 INLMAGSRLPAYCASMGRVLLAWLDESEARTILEQTELRARTPFTQKDPEKLMEELRRIR 184 Query: 192 ERGFVLQEGFFETSISTVAAPVRDHSGLVVAALGATIPSPHIDASQL 238 +GF + + E + ++A PV +H G VVAAL P H++ S L Sbjct: 185 AQGFAVNDQELELGLRSIAVPVFNHRGAVVAALNIGAPVAHVEVSDL 231 >PA0155 [K] COG1414 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 279 Score = 113 bits (282), Expect = 5e-25, Method: Compositional matrix adjust. Identities = 73/224 (32%), Positives = 123/224 (54%), Gaps = 3/224 (1%) Query: 3 EEESQDKYSVPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVE 62 E + D + L RGL ++ F + + L+ +++ R +IPR+ V R L TL ++G+ Sbjct: 24 EAFTGDPNFMTSLARGLAVIHAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLMQLGYA- 82 Query: 63 RADGGRDYRLGMSVLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVA 122 GR Y L VL LG YL+S L +P+LDRL +++ +C++ +G ++Y+A Sbjct: 83 -TTDGRTYSLLPKVLTLGHAYLSSTPLAITAQPILDRLSEQLHEACSMATLEGDDVLYIA 141 Query: 123 KSVT-QTAFTSHVNVGTRLPAHATVLGRVLLEDLSLPQLRALYPEQHLEVFSSNTPKTVV 181 +S T Q + +NVG+RLPA+ T +GR+LL L L A + ++ +S T T Sbjct: 142 RSATPQRLISVDLNVGSRLPAYCTSMGRILLAALDDDALHAYFGGVEMQAKTSRTLYTPE 201 Query: 182 ELFDMVQADKERGFVLQEGFFETSISTVAAPVRDHSGLVVAALG 225 L + + +G+ + + E + ++A PVRD +G V+AAL Sbjct: 202 TLLPCLVEIRRQGWCIVDQELEVGLRSLAVPVRDSAGHVLAALN 245 >yagI [K] COG1414 Transcriptional regulator Eco Escherichia coli K12 Length = 252 Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 68/247 (27%), Positives = 125/247 (50%) Query: 12 VPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVERADGGRDYR 71 + +ER L++L F+ Q L ++++ + + +ST+ LL TL+ G++++ YR Sbjct: 4 IQSVERALQILDLFNEQATELKITDISKLMGLSKSTLHSLLKTLQLHGYIDQNPENGKYR 63 Query: 72 LGMSVLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAKSVTQTAFT 131 LGM ++ G + S+++ + + L L G + +L + DGR VY+ K + A Sbjct: 64 LGMKLVERGHFVVGSIDIRQKAKGWLTELSRRTGQTTHLGILDGREGVYIEKIEGKLAAI 123 Query: 132 SHVNVGTRLPAHATVLGRVLLEDLSLPQLRALYPEQHLEVFSSNTPKTVVELFDMVQADK 191 ++ +G RLP HAT +G+VL+ L +L AL F+ T + L + + Sbjct: 124 AYSRIGRRLPVHATAIGKVLIAWLGEAELNALLEGYQYTTFTPATLASREALMSALAQTR 183 Query: 192 ERGFVLQEGFFETSISTVAAPVRDHSGLVVAALGATIPSPHIDASQLDVIVARVRETAAE 251 E+G+ L E + VA PV +H V+AAL + + +D ++L ++++ Sbjct: 184 EQGYALDSEENEQGVRCVAVPVWNHESRVIAALSLSTLTSRVDDAELANFREQLQQAGLA 243 Query: 252 LSRLLDH 258 LSR L + Sbjct: 244 LSRALGY 250 >Cgl2340 [K] COG1414 Transcriptional regulator Cgl Corynebacterium glutamicum Length = 255 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 65/219 (29%), Positives = 118/219 (53%), Gaps = 2/219 (0%) Query: 12 VPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVERADGGRDYR 71 V RGL ++ FS + + + E+A + + R+T R L TL +G+ D ++ Sbjct: 9 VQSFARGLSVIRSFSADNPSQTLSEVASQTGLSRATARRFLHTLTDLGYAVNNDS--RFQ 66 Query: 72 LGMSVLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAKSVTQTAFT 131 L VL LG YL++L L I +P L+ L ++G S ++ V DG I+YV + + T Sbjct: 67 LTPRVLELGASYLSALSLPAIAQPRLEVLSRQVGESSSMSVLDGTDIIYVCRVPVRRIMT 126 Query: 132 SHVNVGTRLPAHATVLGRVLLEDLSLPQLRALYPEQHLEVFSSNTPKTVVELFDMVQADK 191 ++ +GTR PA+AT +GR++L +L +L + E ++ + ++ + + + A + Sbjct: 127 VNITIGTRFPAYATSMGRIMLANLPEEELDEMLAAAPPEQLTTRSLTSIASIREEIIATR 186 Query: 192 ERGFVLQEGFFETSISTVAAPVRDHSGLVVAALGATIPS 230 ERG+ L + E + ++AAP+ + G VVA++ + S Sbjct: 187 ERGWSLVDQELEPGLRSLAAPITNAQGEVVASINVSTQS 225