BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1254.p (189 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0666 [L] COG2818 3-methyladenine DNA glycosylase Rso Ralstoni... 207 1e-53 VC1672 [L] COG2818 3-methyladenine DNA glycosylase Vch Vibrio ch... 200 1e-51 lin1680 [L] COG2818 3-methyladenine DNA glycosylase Lin Listeria... 196 2e-50 STM3642 [L] COG2818 3-methyladenine DNA glycosylase Sty Salmonel... 195 4e-50 Ztag [L] COG2818 3-methyladenine DNA glycosylase EcZ Escherichia... 193 2e-49 >RSp0666 [L] COG2818 3-methyladenine DNA glycosylase Rso Ralstonia solanacearum Length = 190 Score = 207 bits (527), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 98/178 (55%), Positives = 125/178 (70%), Gaps = 1/178 (0%) Query: 7 RCGWVNLANPRYVDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRDSYREAFD 66 RC WV +P + YHD EWG P HD+ L+EML LEGAQAGLSW+T+L KR Y+E FD Sbjct: 3 RCCWVG-EDPLMIAYHDTEWGTPSHDDRHLYEMLVLEGAQAGLSWQTILRKRARYQEVFD 61 Query: 67 GWDADKIARYDERRVAQLLANPGIVRNRLKVAATIGNARAYLKLCEEVGGLDPYLWGHVD 126 G+D ++AR+ R+ LLA+PGIVRNR KV A + NAR L++ + VG LD +LW V Sbjct: 62 GFDPARVARFTPARIETLLADPGIVRNRAKVEAAVVNARKVLEVQDAVGSLDGFLWAFVG 121 Query: 127 GQPIVNRWASLADCPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVRDC 184 G+P+VNRW+S D PA T S A+SK LA RGFKFVG TI YA++Q G+++DH C Sbjct: 122 GRPVVNRWSSYRDAPASTEASKAMSKALAARGFKFVGPTICYAFMQATGMVDDHEAGC 179 >VC1672 [L] COG2818 3-methyladenine DNA glycosylase Vch Vibrio cholerae Length = 193 Score = 200 bits (509), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 96/188 (51%), Positives = 126/188 (67%), Gaps = 1/188 (0%) Query: 1 MNPSPIRCGWVNLANPRYVDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRDS 60 MN C W + +P +YHD EWG HD+T+LFE L LEGAQAGLSW TVL KR+ Sbjct: 2 MNAEQGVCAWA-MNHPLEREYHDKEWGRAVHDDTKLFEFLTLEGAQAGLSWLTVLKKREG 60 Query: 61 YREAFDGWDADKIARYDERRVAQLLANPGIVRNRLKVAATIGNARAYLKLCEEVGGLDPY 120 YR+AF G+D ++A+ DE V Q++A +V++R K+A+ NARA L L +E G LD Sbjct: 61 YRQAFLGYDLQRLAQCDESHVEQIIAEYDVVKHRGKIASVFSNARAALALQQEFGSLDAA 120 Query: 121 LWGHVDGQPIVNRWASLADCPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDH 180 LW V GQP +NRW S++D PA T S A+SK L +RGFKFVG TI YA++Q G++NDH Sbjct: 121 LWQFVGGQPKINRWVSMSDVPASTEESKAMSKFLKKRGFKFVGETICYAFMQACGLVNDH 180 Query: 181 VRDCHCHA 188 + C H+ Sbjct: 181 LVGCPNHS 188 >lin1680 [L] COG2818 3-methyladenine DNA glycosylase Lin Listeria innocua Length = 193 Score = 196 bits (499), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 92/183 (50%), Positives = 126/183 (68%), Gaps = 1/183 (0%) Query: 6 IRCGWVNLANPRYVDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRDSYREAF 65 +RC W ++ +P + YHD EW VP D+T LFEMLNLEGAQAGLSW+ +L+KR +Y+EAF Sbjct: 5 LRCPW-SINDPFELAYHDGEWCVPSKDDTYLFEMLNLEGAQAGLSWKLILHKRKAYQEAF 63 Query: 66 DGWDADKIARYDERRVAQLLANPGIVRNRLKVAATIGNARAYLKLCEEVGGLDPYLWGHV 125 +D DK AR + +A++++ IV+NRLKV A NA A K+ E G Y+W Sbjct: 64 FHFDIDKCARLTDEDLARIVSEAAIVKNRLKVKAVRTNALATQKVQAEFGSFANYIWSFT 123 Query: 126 DGQPIVNRWASLADCPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVRDCH 185 +G+ I+N W + + PAKT LS+ ISKDL +RGFKFVG IIY+YLQ +G+++DH+R C Sbjct: 124 NGERIINEWQGMGEVPAKTELSEKISKDLKKRGFKFVGPVIIYSYLQAIGILDDHLRSCP 183 Query: 186 CHA 188 H Sbjct: 184 FHT 186 >STM3642 [L] COG2818 3-methyladenine DNA glycosylase Sty Salmonella typhimurium LT2 Length = 193 Score = 195 bits (496), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 92/183 (50%), Positives = 123/183 (67%), Gaps = 1/183 (0%) Query: 7 RCGWVNLANPRYVDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRDSYREAFD 66 RC WV+ +P Y+ YHD+EWGVP D +LFEM+ LEG QAGLSW TVL KR++YR F Sbjct: 3 RCDWVS-QDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRACFH 61 Query: 67 GWDADKIARYDERRVAQLLANPGIVRNRLKVAATIGNARAYLKLCEEVGGLDPYLWGHVD 126 +D +IA E V LL N GI+R+R K+ A I NARA+L + + ++W VD Sbjct: 62 QFDPVRIAAMQEEDVEHLLQNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSFVD 121 Query: 127 GQPIVNRWASLADCPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVRDCHC 186 GQP + + ASL + P TP SDA++K L +RGFKFVG+TI Y+++Q G++NDH+ C C Sbjct: 122 GQPQITQAASLDEIPTSTPASDALAKALKKRGFKFVGTTICYSFMQACGLVNDHITGCFC 181 Query: 187 HAG 189 H G Sbjct: 182 HPG 184 >Ztag [L] COG2818 3-methyladenine DNA glycosylase EcZ Escherichia coli O157:H7 EDL933 Length = 187 Score = 193 bits (491), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 91/183 (49%), Positives = 126/183 (68%), Gaps = 1/183 (0%) Query: 7 RCGWVNLANPRYVDYHDHEWGVPCHDETRLFEMLNLEGAQAGLSWETVLNKRDSYREAFD 66 RCGWV+ +P Y+ YHD+EWGVP D +LFEM+ LEG QAGLSW TVL KR++YR F Sbjct: 3 RCGWVS-QDPLYIAYHDNEWGVPETDRKKLFEMICLEGQQAGLSWITVLKKRENYRACFH 61 Query: 67 GWDADKIARYDERRVAQLLANPGIVRNRLKVAATIGNARAYLKLCEEVGGLDPYLWGHVD 126 +D K+A E V +L+ + GI+R+R K+ A IGNARAYL++ + ++W V+ Sbjct: 62 QFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFADFVWSFVN 121 Query: 127 GQPIVNRWASLADCPAKTPLSDAISKDLARRGFKFVGSTIIYAYLQGVGVINDHVRDCHC 186 QP V + +L++ P TP SDA+SK L +RGFKFVG+TI Y+++Q G++NDHV C C Sbjct: 122 HQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTTICYSFMQACGLVNDHVVGCCC 181 Query: 187 HAG 189 + G Sbjct: 182 YPG 184