BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.1235.p         (242 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSp0355 [QR] COG0500 SAM-dependent methyltransferases Rso Ralsto...   244   1e-64
HP1483 [H] COG2226 Methylase involved in ubiquinone/menaquinone ...    63   7e-10
ML1723 [QR] COG0500 SAM-dependent methyltransferases Mle Mycobac...    62   2e-09
CAC3419 [QR] COG0500 SAM-dependent methyltransferases Cac Clostr...    61   2e-09
Rv3038c [QR] COG0500 SAM-dependent methyltransferases Mtu Mycoba...    61   2e-09

>RSp0355 [QR] COG0500 SAM-dependent methyltransferases Rso Ralstonia
           solanacearum
          Length = 246

 Score =  244 bits (623), Expect = 1e-64,   Method: Compositional matrix adjust.
 Identities = 125/233 (53%), Positives = 165/233 (70%), Gaps = 2/233 (0%)

Query: 9   PAALPEHVPETAFGLWFLRTPTWTLHVLERAMLDLERLIPQRRSSYPVVADVGCGWGRSL 68
           P  +   VPETAFG+WFLRT TW  HVL  A+ DL+RLI       PV+ADVGCG G S 
Sbjct: 10  PERIGSFVPETAFGIWFLRTHTWAHHVLRVAVNDLKRLITTSLPVAPVIADVGCGQGISF 69

Query: 69  KKLQTRFTPQRLIGMDIDPAMIEAARAEADAEGLHAEFIQCSSAQMRLEDSSVDLLFCHQ 128
           + L++ F PQR+IG+D     + AA+  A A     + +    A + L D+SVD++FCHQ
Sbjct: 70  RLLESAFAPQRMIGIDFHRPSLAAAKQAAAALATPVDLLHGDCAALPLPDASVDMVFCHQ 129

Query: 129 TFHHLVDQEEAIREFYRVLKPGGILLFAESTKRYIHSWIIRLLFRHPMEVQKTAEQYLAL 188
           TFHHLV+Q+ A+ EF+RVLKPGG+LLFAEST+ YI SW+IRLLFRHPM VQK+A+ YL +
Sbjct: 130 TFHHLVEQDRALAEFHRVLKPGGLLLFAESTEVYIKSWVIRLLFRHPMHVQKSAQGYLDM 189

Query: 189 VRSAGFQVAPQSISYPYLWWSR-EDLGILERVFGIKPR-AEREETLINLVAVK 239
           +R+ GF    ++IS PYLWWSR  D G+LER+   +P+  +R ETL+N+VA+K
Sbjct: 190 IRAGGFAFEDRNISLPYLWWSRARDFGLLERLGLHRPKPGKRRETLVNVVAIK 242


>HP1483 [H] COG2226 Methylase involved in ubiquinone/menaquinone
           biosynthesis Hpy Helicobacter pylori 26695
          Length = 246

 Score = 62.8 bits (151), Expect = 7e-10,   Method: Compositional matrix adjust.
 Identities = 46/157 (29%), Positives = 76/157 (48%), Gaps = 16/157 (10%)

Query: 20  AFGLWFLRTPTWTLHVLERAMLDLERLIPQRRSSYPVVADVGCGWGRSL-----KKLQTR 74
           +FGL       W     E A L LE     R      + DV CG G  L       L   
Sbjct: 31  SFGL----DVKWRERACEHAFLFLENKKALR------LVDVACGTGDMLVAWQKSALNCG 80

Query: 75  FTPQRLIGMDIDPAMIEAARAEADAEGLHAEFIQCSSAQMR-LEDSSVDLLFCHQTFHHL 133
              +  +G+D    M+E A  + +     A FIQ  +  ++ +E++SVD+L       ++
Sbjct: 81  IEFKECLGIDPSNNMLELAIKKCEELENKASFIQAQAKDLKGVENNSVDILSIAYGLRNV 140

Query: 134 VDQEEAIREFYRVLKPGGILLFAESTKRYIHSWIIRL 170
           V+++EA++EF+RVLKP G+L+  E  K+   +W+ ++
Sbjct: 141 VERQEALKEFFRVLKPRGVLVILEFLKKDNPTWLDKI 177


>ML1723 [QR] COG0500 SAM-dependent methyltransferases Mle Mycobacterium
           leprae
          Length = 327

 Score = 61.6 bits (148), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 33/103 (32%), Positives = 50/103 (48%)

Query: 54  YPVVADVGCGWGRSLKKLQTRFTPQRLIGMDIDPAMIEAARAEADAEGLHAEFIQCSSAQ 113
           Y    ++GCG G  L  L      +R    D+ P M++ A     + GL        +  
Sbjct: 78  YDCALELGCGTGFFLLNLIQSGVARRGSVTDLSPGMVKIATRNGQSLGLDINGRVADAEG 137

Query: 114 MRLEDSSVDLLFCHQTFHHLVDQEEAIREFYRVLKPGGILLFA 156
           +  +D++ DL+  H   HH+ D E ++RE  RVLKPGG  +FA
Sbjct: 138 IPYDDNTFDLVVGHAVLHHIPDVELSLREVLRVLKPGGRFVFA 180


>CAC3419 [QR] COG0500 SAM-dependent methyltransferases Cac Clostridium
           acetobutylicum
          Length = 207

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 4/120 (3%)

Query: 51  RSSYPVVADVGCGWGRSLKKLQTRFTPQRLIGMDIDPAMIEAARAEADAEGLHAEFIQCS 110
           R++   V DVGCG G  LK L  +     L G+D+   MIE A+         AE     
Sbjct: 45  RANPKTVLDVGCGTGNVLKIL-AKDENLSLYGLDLSEKMIEIAKKNLKG---RAELKLGD 100

Query: 111 SAQMRLEDSSVDLLFCHQTFHHLVDQEEAIREFYRVLKPGGILLFAESTKRYIHSWIIRL 170
           S  M  + +S D++ C+ +FHH  + ++ + E  R+LK  G L+  + T   I+  I+ L
Sbjct: 101 SENMPWKSNSFDVIVCNASFHHYPNPKKVLIEMKRILKKDGTLIIGDPTAPVIYRQILNL 160


>Rv3038c [QR] COG0500 SAM-dependent methyltransferases Mtu Mycobacterium
           tuberculosis H37Rv
          Length = 327

 Score = 61.2 bits (147), Expect = 2e-09,   Method: Compositional matrix adjust.
 Identities = 34/103 (33%), Positives = 50/103 (48%)

Query: 54  YPVVADVGCGWGRSLKKLQTRFTPQRLIGMDIDPAMIEAARAEADAEGLHAEFIQCSSAQ 113
           Y    ++GCG G  L  L      +R    D+ P M++ A     A GL  +     +  
Sbjct: 78  YDRALELGCGTGFFLLNLIQAGVARRGSVTDLSPGMVKVATRNGQALGLDIDGRVADAEG 137

Query: 114 MRLEDSSVDLLFCHQTFHHLVDQEEAIREFYRVLKPGGILLFA 156
           +  +D + DL+  H   HH+ D E ++RE  RVLKPGG  +FA
Sbjct: 138 IPYDDDAFDLVVGHAVLHHIPDVELSLREVVRVLKPGGRFVFA 180