BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1196.p (282 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1527 [H] COG0294 Dihydropteroate synthase and related enzymes... 327 2e-89 VC0638 [H] COG0294 Dihydropteroate synthase and related enzymes ... 270 3e-72 PA4750 [H] COG0294 Dihydropteroate synthase and related enzymes ... 266 3e-71 XF0091 [H] COG0294 Dihydropteroate synthase and related enzymes ... 261 1e-69 HI1464 [H] COG0294 Dihydropteroate synthase and related enzymes ... 257 2e-68 >RSc1527 [H] COG0294 Dihydropteroate synthase and related enzymes Rso Ralstonia solanacearum Length = 291 Score = 327 bits (838), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 166/279 (59%), Positives = 207/279 (74%), Gaps = 4/279 (1%) Query: 2 TQAFLKCGRFRLPVQIGRRPLVMGILNLTPDSFSDGGRHHSLELALSHAEQMIADGVDII 61 T +CGRFR P RRPLVMGILN+TPDSFSDGGRH + + AL HAEQ+IA+G D+I Sbjct: 7 TTTHFQCGRFRYPRD--RRPLVMGILNVTPDSFSDGGRHATRDAALRHAEQLIAEGADLI 64 Query: 62 DIGGESTRPGIAPLSLEQELERVMPVIYALRDCGKPLSLDTYKPAVMREALAAEVDMIND 121 DIGGES+RPG APL L++EL+RVMP++ ALR+CG+PLS+DTYKP VMR L A D+IND Sbjct: 65 DIGGESSRPGAAPLGLQEELDRVMPIVEALRECGRPLSIDTYKPDVMRATLDAGADLIND 124 Query: 122 INGFRAEGAIEVVKDSEAGLCVMHMQGQPQTMQQAPEYEDVVSEVEQFLQQQVDLMRDAG 181 I GFR GAIE V AGLC+MHMQ P+TMQ+AP Y D+++EV FLQ Q ++ AG Sbjct: 125 IWGFRKPGAIEAVAQGHAGLCLMHMQRDPETMQEAPSYTDLMAEVGAFLQAQAQVLLAAG 184 Query: 182 IGRERICIDPGFGFGKTVEHNLTLLKNTRRLIDTLGLPLLAGMSRKSMIGAVT-GKPLER 240 + ERI +DPGFGFGKT +HNL +L N + +GLPLL G+SRKS +GAV GKP Sbjct: 185 VAAERIALDPGFGFGKTPDHNLIML-NRLEHFERMGLPLLVGLSRKSTLGAVLGGKPPAE 243 Query: 241 RLAGSIGAALAAAQQGAMIIRVHDAAETVDALAMWQAGR 279 R+ S+ AAL AA++GA I+RVHD TV+A+ +W A R Sbjct: 244 RITASVAAALLAAERGAFIVRVHDVRPTVEAIQLWWAMR 282 >VC0638 [H] COG0294 Dihydropteroate synthase and related enzymes Vch Vibrio cholerae Length = 278 Score = 270 bits (689), Expect = 3e-72, Method: Compositional matrix adjust. Identities = 139/258 (53%), Positives = 181/258 (70%), Gaps = 3/258 (1%) Query: 21 PLVMGILNLTPDSFSDGGRHHSLELALSHAEQMIADGVDIIDIGGESTRPGIAPLSLEQE 80 P+VMGILN TPDSFSDGGR+ L++AL+ A+QMI GV IIDIGGESTRPG ++LE+E Sbjct: 16 PVVMGILNTTPDSFSDGGRYVDLDVALARAQQMIDLGVAIIDIGGESTRPGAPDVALEEE 75 Query: 81 LERVMPVIYALRDCGKP--LSLDTYKPAVMREALAAEVDMINDINGFRAEGAIEVVKDSE 138 L+RV+P+I A+R +S+DT K VMR+ALAA D+IND+ + GA+EV ++ Sbjct: 76 LQRVIPLIKAIRKQNAEVWISIDTSKAEVMRQALAAGADLINDVRALQEPGALEVAAQAQ 135 Query: 139 AGLCVMHMQGQPQTMQQAPEYEDVVSEVEQFLQQQVDLMRDAGIGRERICIDPGFGFGKT 198 +C+MHMQGQP+TMQ P Y +++ EV QFL +++ AGI RE I +DPGFGFGK+ Sbjct: 136 VPVCIMHMQGQPRTMQANPHYYNIIEEVCQFLAERIAQCEAAGIKRENIILDPGFGFGKS 195 Query: 199 VEHNLTLLKNTRRLIDTLGLPLLAGMSRKSMIGAVTGKPLERRLAGSIGAALAAAQQGAM 258 V+HN LL + + GLP+LAGMSRKSMI K +AGS+ A AAQ+GA Sbjct: 196 VQHNYHLLAHLEQF-HRFGLPVLAGMSRKSMIFKTLNKQPAECVAGSVACATLAAQKGAQ 254 Query: 259 IIRVHDAAETVDALAMWQ 276 IIRVHD +T+DAL M Q Sbjct: 255 IIRVHDVEQTIDALKMVQ 272 >PA4750 [H] COG0294 Dihydropteroate synthase and related enzymes Pae Pseudomonas aeruginosa Length = 283 Score = 266 bits (680), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 144/273 (52%), Positives = 187/273 (68%), Gaps = 5/273 (1%) Query: 6 LKCGRFRLPVQIGRRPLVMGILNLTPDSFSDGGRHHSLELALSHAEQMIADGVDIIDIGG 65 L CG L + RP VMGILN+TPDSFSDGGR+ L+ AL HAE+M+ +G +ID+GG Sbjct: 10 LPCGSRVLDLA---RPHVMGILNVTPDSFSDGGRYDRLDDALRHAERMVLEGATLIDVGG 66 Query: 66 ESTRPGIAPLSLEQELERVMPVIYAL-RDCGKPLSLDTYKPAVMREALAAEVDMINDING 124 ESTRPG +S +ELERV PV+ + R+ +S+DT PAVMRE +IND+ Sbjct: 67 ESTRPGARSVSPTEELERVAPVVERIARELDVVISVDTSTPAVMRETARLGAGLINDVRS 126 Query: 125 FRAEGAIEVVKDSEAGLCVMHMQGQPQTMQQAPEYEDVVSEVEQFLQQQVDLMRDAGIGR 184 + +GA++ DS +C+MHM+G+PQTMQ AP Y+DVV+EV FLQ++VD AGI R Sbjct: 127 LQRDGALDAAVDSGLAVCLMHMRGEPQTMQDAPAYQDVVAEVGAFLQERVDACVAAGIDR 186 Query: 185 ERICIDPGFGFGKTVEHNLTLLKNTRRLIDTLGLPLLAGMSRKSMIGAVTGKPLERRLAG 244 ER+ +DPGFGF KT+EHNL L ++ + L LGLPLL G+SRKSMIG V G+ ++ RL G Sbjct: 187 ERLLLDPGFGFAKTLEHNLVLFRHLQAL-HGLGLPLLVGVSRKSMIGKVLGREVDERLYG 245 Query: 245 SIGAALAAAQQGAMIIRVHDAAETVDALAMWQA 277 S+ A A +GA IIRVHD A TVD + M A Sbjct: 246 SLALAALALAKGARIIRVHDVAATVDVMRMISA 278 >XF0091 [H] COG0294 Dihydropteroate synthase and related enzymes Xfa Xylella fastidiosa 9a5c Length = 298 Score = 261 bits (667), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 140/260 (53%), Positives = 183/260 (70%), Gaps = 6/260 (2%) Query: 20 RPLVMGILNLTPDSFSDGGRHHSLELALSHAEQMIADGVDIIDIGGESTRPGIAPLSLEQ 79 RPLVMGILN+TPDSFSDGG H S++ A++H ++IA+G DIIDIGGESTRPG AP+ LE+ Sbjct: 19 RPLVMGILNVTPDSFSDGGLHDSVDAAVAHGLRLIAEGADIIDIGGESTRPGAAPVPLEE 78 Query: 80 ELERVMPVIYALRDCGKP-LSLDTYKPAVMREALAAEVDMINDINGFRAEGAIEVVKDSE 138 EL RV+PVI AL K +S+DT+KP VMR A+AA +INDI R GA+ + Sbjct: 79 ELLRVVPVIKALTAYDKAVISVDTFKPEVMRAAVAAGAGLINDIYALRTPGALGAAAELA 138 Query: 139 AGLCVMHMQGQPQTMQQAPEYEDVVSEVEQFLQQQVDLMRDAGIGRERICIDPGFGFGKT 198 + +MHM+G+P + Q P+Y+ VV EV +FL +++ AGI R R+ IDPGF F KT Sbjct: 139 VPVILMHMKGEPHS-TQTPQYDHVVDEVHRFLAERIFAAEIAGIERHRLLIDPGFSFSKT 197 Query: 199 VEHNLTLLKNTRRLIDTLGLPLLAGMSRKSMIGAVTGK--PLERRLAGSIGAALAAAQQG 256 EHN+ LL R + LG+PLLAG+SRKS +G +TG+ P+ER A S+ A L A Q+G Sbjct: 198 TEHNIALLAALERFTN-LGIPLLAGLSRKSSLGELTGRQLPIERVYA-SVAAHLIAVQRG 255 Query: 257 AMIIRVHDAAETVDALAMWQ 276 A+I+RVHD A VDAL +WQ Sbjct: 256 ALIVRVHDVAAMVDALKVWQ 275 >HI1464 [H] COG0294 Dihydropteroate synthase and related enzymes Hin Haemophilus influenzae Length = 275 Score = 257 bits (657), Expect = 2e-68, Method: Compositional matrix adjust. Identities = 132/260 (50%), Positives = 174/260 (66%), Gaps = 6/260 (2%) Query: 21 PLVMGILNLTPDSFSDGGRHHSLELALSHAEQMIADGVDIIDIGGESTRPGIAPLSLEQE 80 P +MGILN TPDSFSD G+ SL+ AL E+M+ +G IIDIGGESTRP +S ++E Sbjct: 15 PQIMGILNFTPDSFSDSGQFFSLDKALFQVEKMLEEGATIIDIGGESTRPNADEVSEQEE 74 Query: 81 LERVMPVIYALR---DCGKPLSLDTYKPAVMREALAAEVDMINDINGFRAEGAIEVVKDS 137 L RV+PV+ A+R DC +S+D+ K VMREA +D+INDI + A+E Sbjct: 75 LHRVVPVVEAVRNRFDCW--ISVDSSKAVVMREAANVGMDLINDIRALQEPNALETAVKL 132 Query: 138 EAGLCVMHMQGQPQTMQQAPEYEDVVSEVEQFLQQQVDLMRDAGIGRERICIDPGFGFGK 197 +C+MHMQGQP+TMQ P YE+VV +V FLQ++ + AGI +E + D GFGFGK Sbjct: 133 ALPVCIMHMQGQPRTMQANPYYENVVQDVLAFLQKRTNECLSAGIKKENLIWDMGFGFGK 192 Query: 198 TVEHNLTLLKNTRRLIDTLGLPLLAGMSRKSMIGAVTGKPLERRLAGSIGAALAAAQQGA 257 +V+HN LL+N +G P+LAG+SRKSMIGAV KP+++R+ GS AL A Q+GA Sbjct: 193 SVQHNYQLLQNLNEFCQ-IGYPVLAGLSRKSMIGAVLDKPVDQRIIGSAAGALIAVQKGA 251 Query: 258 MIIRVHDAAETVDALAMWQA 277 I+RVHD A T D L +WQA Sbjct: 252 KILRVHDVAATSDMLKVWQA 271