BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0001.1122.p         (95 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA2508 Non COG                                                        108   2e-24
Cgl2349 [Q] COG4829 Muconolactone delta-isomerase Cgl Corynebact...    94   8e-20
Rv0316 [Q] COG4829 Muconolactone delta-isomerase Mtu Mycobacteri...    54   7e-08
MT0330 [Q] COG4829 Muconolactone delta-isomerase MtC Mycobacteri...    54   7e-08
SSO2865 [H] COG0190 5,10-methylene-tetrahydrofolate dehydrogenas...    42   3e-04

>PA2508 Non COG
          Length = 96

 Score =  108 bits (271), Expect = 2e-24,   Method: Compositional matrix adjust.
 Identities = 46/91 (50%), Positives = 66/91 (72%)

Query: 1  MLFMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVVGQYANVSIFNVSG 60
          MLF V+M V +P  +D   A++LK +EKEM+Q+LQREG WR LWR+ G YAN S+F++  
Sbjct: 1  MLFHVKMTVKLPVDMDPQQAERLKAEEKEMAQRLQREGSWRHLWRIAGHYANYSLFDLPS 60

Query: 61 NDELHNLLSALPLYPFMTISVTPLTQHPSAI 91
           + LH+ L+ LPL+P+M I +  L +HPS+I
Sbjct: 61 VEALHDTLTRLPLFPYMDIEIDGLCRHPSSI 91


>Cgl2349 [Q] COG4829 Muconolactone delta-isomerase Cgl Corynebacterium
          glutamicum
          Length = 97

 Score = 94.0 bits (232), Expect = 8e-20,   Method: Compositional matrix adjust.
 Identities = 40/91 (43%), Positives = 59/91 (64%)

Query: 1  MLFMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVVGQYANVSIFNVSG 60
          MLF+ +M V  P ++D  V    +  EK  S  LQ  G  + +WRVVG+YAN SIF+V  
Sbjct: 1  MLFLARMDVVFPDSMDADVMADFQAKEKAYSGDLQSRGIMKAIWRVVGEYANYSIFDVDD 60

Query: 61 NDELHNLLSALPLYPFMTISVTPLTQHPSAI 91
          +DELH +LS  P++ +M + +TPL +HP+A+
Sbjct: 61 HDELHAILSGFPMFKYMNVKITPLAKHPNAL 91


>Rv0316 [Q] COG4829 Muconolactone delta-isomerase Mtu Mycobacterium
          tuberculosis H37Rv
          Length = 204

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 1  MLFMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVV---GQYANVSIFN 57
          M F+V M   +P ++     ++++  E   S++L  +GK   LWR     G++  + +F 
Sbjct: 1  MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60

Query: 58 VSGNDELHNLLSALPLYPFMTISVTPLTQHPS 89
             N EL  LL+++P   + T  VTPL  HP+
Sbjct: 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92



 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 3   FMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVV----GQYANVSIFNV 58
           F++   + +P      V D     E   + +L   G    LW +     GQ   + ++  
Sbjct: 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167

Query: 59  SGNDELHNLLSALPLYPFMTISVTPLTQHP 88
               EL  +L +LPL  +MTI  TPL+ HP
Sbjct: 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197


>MT0330 [Q] COG4829 Muconolactone delta-isomerase MtC Mycobacterium
          tuberculosis CDC1551
          Length = 204

 Score = 54.3 bits (129), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 28/92 (30%), Positives = 48/92 (52%), Gaps = 3/92 (3%)

Query: 1  MLFMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVV---GQYANVSIFN 57
          M F+V M   +P ++     ++++  E   S++L  +GK   LWR     G++  + +F 
Sbjct: 1  MEFLVTMTTRVPDSMPADAVERVRAREAARSRELAAQGKLLRLWRPPLRPGEWRTLGLFA 60

Query: 58 VSGNDELHNLLSALPLYPFMTISVTPLTQHPS 89
             N EL  LL+++P   + T  VTPL  HP+
Sbjct: 61 ADDNGELEQLLASMPPRSWRTDDVTPLGAHPN 92



 Score = 38.1 bits (87), Expect = 0.005,   Method: Compositional matrix adjust.
 Identities = 25/90 (27%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 3   FMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVV----GQYANVSIFNV 58
           F++   + +P      V D     E   + +L   G    LW +     GQ   + ++  
Sbjct: 109 FLIATTIMVPPGTPAQVVDDTVAREARRAPELAGRGHLVRLWALPDGPDGQR-TLGLWRA 167

Query: 59  SGNDELHNLLSALPLYPFMTISVTPLTQHP 88
               EL  +L +LPL  +MTI  TPL+ HP
Sbjct: 168 RDPGELMAILESLPLAGWMTIETTPLSPHP 197


>SSO2865 [H] COG0190 5,10-methylene-tetrahydrofolate
          dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
          Sso Sulfolobus solfataricus
          Length = 104

 Score = 42.0 bits (97), Expect = 3e-04,   Method: Compositional matrix adjust.
 Identities = 26/92 (28%), Positives = 49/92 (53%), Gaps = 6/92 (6%)

Query: 1  MLFMVQMQVNIPATLDKAVADQLKKDEKEMSQKLQREGKWRDLWRVVGQYANVSIFNVSG 60
          MLF++  ++  P  + +    ++ K E E +    + GK + L++V G+   V+I +V+ 
Sbjct: 2  MLFLLWFKIKQPTNITQKQLMEIWKREAEAAMPAVKAGKIKGLYKVTGRREVVAIIDVNS 61

Query: 61 NDELHNLLSALPLYP----FMTISVTPLTQHP 88
          ++EL  +L  LP+       +TI VT +  HP
Sbjct: 62 HEELDGILETLPIVKELGHSLTIEVTAI--HP 91