BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1093.p (401 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2949 [GEPR] COG0477 Permeases of the major facilitator superf... 205 2e-52 RSp1614 [GEPR] COG0477 Permeases of the major facilitator superf... 162 1e-39 BS_yjmG [GEPR] COG0477 Permeases of the major facilitator superf... 150 4e-36 yhaU [GEPR] COG0477 Permeases of the major facilitator superfami... 144 3e-34 ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfam... 144 3e-34 >lin2949 [GEPR] COG0477 Permeases of the major facilitator superfamily Lin Listeria innocua Length = 401 Score = 205 bits (521), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 125/380 (32%), Positives = 204/380 (53%), Gaps = 3/380 (0%) Query: 2 ISAVQTRIYKYAVLALLYLGWCISYIDRAAITFAATHIASEFHLKPSDLGLLLSSFFLGY 61 ++ V+ + VL +L++G+ Y+D+ I + ++ + PS GL+LS+FFLGY Sbjct: 1 MNQVKGEKHSLMVLLVLFIGYTSVYVDKYTIGISLVTVSQDLGFDPSQKGLILSAFFLGY 60 Query: 62 SLLQLPGGWLADRFGSRPVIVISILMWSLFTGLTGMAWSITSLVVIRFFFG-IGEGSFPA 120 +L Q+P G+L +R G+RPV+ ISI++ LF + G +S+ LVVIRF G G +P Sbjct: 61 TLFQIPMGYLNNRIGARPVLAISIIIVGLFLIIFGFGYSLLFLVVIRFLSGAFGHAGYPP 120 Query: 121 ASIKGVAEHFDKGERPKMSSVLMSSNYIGSMLAPVIIAPLILHFGWRNVFHYIGIVGIIF 180 + ++ H +R S +++S+ + + P++IA L+L GWRN +++IGIV +IF Sbjct: 121 SVSNYISLHIPLNKRGFAQSAMLASSGFAAFIGPLLIAQLLLSVGWRNTYYWIGIV-VIF 179 Query: 181 AVAYWLCVRPLSERTDGGKRPVNSKT-ISELMRLPLMWQLVAVWFGLSVVNKGLDSWMPT 239 L V P + + D + K SEL++ +W L+ ++ N GL SW+ + Sbjct: 180 IGLLILLVVPKAPKIDKSTQKEKIKVPFSELLKDKQLWILLLSALFINAANYGLTSWLAS 239 Query: 240 YLMTVRGLDLKAVGLLLPLPYVMAGISTAIGGWLMMRFFNGRERVMLVVSSALTAIFVYF 299 YL RG+ + V + L + I+ IGG+ + RFF G+E +++ S L A VY Sbjct: 240 YLNEARGISISEVSYISSLAGLCILIAGVIGGYFISRFFKGKEPIVIFTFSVLGAFTVYG 299 Query: 300 MYVASDVTGVIIFQCLAYFFKSFVLAACFALPTKILDTRLIGSSVGMVNLGGQAAGFISP 359 +Y+ + II CL F LP K+ I + +N GG GF +P Sbjct: 300 VYLFDQLMLSIICLCLCNIFLIMAFTTLMGLPHKLFKQSHIATKYAAINSGGVLGGFFAP 359 Query: 360 LVIGILVSAFSNYDYAFAFL 379 ++IG LV+A ++Y AF FL Sbjct: 360 MIIGDLVNATNSYQSAFLFL 379 >RSp1614 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 448 Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 123/426 (28%), Positives = 210/426 (49%), Gaps = 39/426 (9%) Query: 6 QTRIYKYAVLALLYLGWCISYIDRAAITFAATHIASEFHLKPSDLGLLLSSFFLGYSLLQ 65 Q ++ V L++ I+YIDR ++ AA HI EFHL ++G+++S+FF Y+LLQ Sbjct: 9 QRSKVRWLVAGLMWAAIAINYIDRTVLSAAAPHIQKEFHLSAVEMGVVMSAFFWSYALLQ 68 Query: 66 LPGGWLADRFGSRPVIVISILMWSLFTGLTGMAWSITSLVVIRFFFGIGE-GSFPAASIK 124 LP G LADRFG + V+ ++L WSL T +TG+A SLV +R G+GE G++P S Sbjct: 69 LPAGILADRFGQKKVLGFAVLWWSLATAVTGLATGFKSLVGLRVALGVGEAGAYP--SNA 126 Query: 125 GVAEH-FDKGERPKMSSVLMSSNYIGSMLAPVIIAPLILHFGWRNVFHYIGIVGIIFAVA 183 G+ F K ER ++++ S + +GS +A +IA L++ F W+ F G +GI++ V Sbjct: 127 GITSRWFPKQERATVAAIFDSGSKLGSAIALPLIAWLLVTFDWKITFTVAGSLGIVWCVV 186 Query: 184 YWLCVRPLSERTDGGKRPVNSKTISELMR---------LPLM-----------WQLVAVW 223 + L R +G VN+ ++ + + P M W + + Sbjct: 187 WALVFRDSPAEHEG----VNAAELAHIQKGLPPARGADAPAMPWTKLLTHRNVWAMCIGF 242 Query: 224 FGLSVVNKGLDSWMPTYLMTVRGLDLKAVGLLLPLPYVMAGISTAIGGWLMMRFF-NGR- 281 F ++ + +W+PTYL+ RG+ L +G + LP ++ GW R + +GR Sbjct: 243 FMINYNSYFFITWLPTYLVKERGMGLMEMGFMASLPLFVSMFVEVFAGWASDRVYASGRL 302 Query: 282 -----ERVMLVVSSALTAIFVYFMYVASDVTGVIIFQCLAYFFKSFVLAACFALPTKILD 336 ++ LV+ + + + S V VI+ C+A + + +ALP + Sbjct: 303 SLTATRKLFLVIGLVMASSIGLAAFAQSAVVAVILL-CIAKSGTTVAASQVWALPADVAP 361 Query: 337 TRLIGSSVGMVNLGGQAAGFISPLVIGILVSAFSNYDYAFAFLISAAIFSV-VVSFFIRT 395 + G+ N G + P+V G +V A ++ A F SAA+ + ++++ Sbjct: 362 GNTVSMVAGLQNSVSNMGGVVGPIVTGAIVGATGSFIPALVF--SAALIGLAILNYLFLL 419 Query: 396 EKSQPI 401 K +PI Sbjct: 420 GKVEPI 425 >BS_yjmG [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 422 Score = 150 bits (380), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 111/416 (26%), Positives = 204/416 (49%), Gaps = 26/416 (6%) Query: 11 KYAVLALLYLGWCISYIDRAAITFAATHIASEFHLKPSDLGLLLSSFFLGYSLLQLPGGW 70 K V+ L+L I+Y+DR+A++ AA I + L + +GL+ SSF +GY++ GG Sbjct: 6 KLPVILFLFLAGVINYLDRSALSIAAPFIQDDLTLSATQMGLIFSSFSIGYAIFNFLGGV 65 Query: 71 LADRFGSRPVIVISILMWSLFTGLTGMAWSITSLVVIRFFFGIGEGSFPAASIKGVAEHF 130 +DR+G++ + +++++WSLF+G +A+ SL++IR FG+GEG A K V F Sbjct: 66 ASDRYGAKLTLFVAMVVWSLFSGAVALAFGFVSLLIIRILFGMGEGPLSATINKMVNNWF 125 Query: 131 DKGERPKMSSVLMSSNYIGSMLAPVIIAPLILHFGWRNVFHYIGIVGIIFAVAYWLCVRP 190 +R + V S +G ++ I+ + + F W+ F I I+G+I+AV ++ V+ Sbjct: 126 PPTQRASVIGVTNSGTPLGGAISGPIVGMIAVAFSWKVSFVLIMIIGLIWAVLWFKFVKE 185 Query: 191 LSERTDGGKRPVNSKTISELMRLPLMWQLVA--------VWFGLSVVNKGLDSWMPTYLM 242 + T + ++T S ++PL + L +F + + +W P+YL+ Sbjct: 186 KPQETIKEAPAIKAET-SPGEKIPLTFYLKQKTVLFTAFAFFAYNYILFFFLTWFPSYLV 244 Query: 243 TVRGLDLKAVGLLLPLPYVMAGISTAIGGWLMMRFFNGRER--------VMLVVSSALTA 294 RGL ++++ ++ +P+++ I A GG++ + R V+LV +A Sbjct: 245 DERGLSVESMSVITVIPWILGFIGLAAGGFVSDYVYKKTARKGVLFSRKVVLVTCLFSSA 304 Query: 295 IFVYFMYVASDVTGVIIFQCLAYFFKSFVLAACFALPTKILDTRLIGSSVGMVNLGGQAA 354 + + F + + G + L+ FF A +A+ ++D +GS G ++ A Sbjct: 305 VLIGFAGLVATTAGAVTLVALSVFFLYLTGAIYWAVIQDVVDQNNVGSVGGFMHFLANTA 364 Query: 355 GFISPLVIGILVSAFSNYDYAFAFLISAAIF-SVVVSFFIR--------TEKSQPI 401 G I P + G +V + AF A+F S+ V F+R TE P+ Sbjct: 365 GIIGPALTGFIVDQTGTFSGAFLLAGGLAVFASLAVIRFVRPIIGKPAGTEAENPV 420 >yhaU [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 444 Score = 144 bits (363), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 121/431 (28%), Positives = 204/431 (47%), Gaps = 48/431 (11%) Query: 3 SAVQTRIYKYAVLALLYLGWCISYIDRAAITFAATHIASEFHLKPSDLGLLLSSFFLGYS 62 V TR Y +L ++++ ++Y DRA ++ A T +A E L +G + S+F Y Sbjct: 11 KGVHTR---YLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYL 67 Query: 63 LLQLPGGWLADRFGSRPVIVISILMWSLFTGLTG------MAWSITSLVVIRFFFGIGEG 116 L+Q+PGGWL D+FGS+ V S+ WSLFT L G +AW+ S+ +RF G E Sbjct: 68 LMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEA 127 Query: 117 -SFPAASIKGVAEHFDKGERPKMSSVLMSSNYIGSMLAPVIIAPLILHFGWRNVFHYIGI 175 SFPA + + VA F ER S++ S+ Y L ++ L +GW +VF +G+ Sbjct: 128 PSFPANA-RIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGV 186 Query: 176 VGIIFAVAYWLCVRPLSERTDGGKRPVNS-KTISE------------------------L 210 +G + A W ++ + TD + K ISE + Sbjct: 187 IGFVL-TALW--IKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYI 243 Query: 211 MRLPLMWQLVAVWFGLSVVNK---GLDSWMPTYLMTVRGLDLKAVGLLLPLPYVMAGIST 267 +L ++ V+FG +N +W P YL+ +G+ + VGL+ +P + Sbjct: 244 KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGG 303 Query: 268 AIGG----WLMMRFFN-GRERVMLVVSSALTAIFVYFMYVASDVTGVIIFQCLAYFFKSF 322 +GG +L+ R + R + +V L A + ++ T V++ LA+F K F Sbjct: 304 VLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGF 363 Query: 323 VLAACFALPTKILDTRLIGSSVGMVNLGGQAAGFISPLVIGILVSAFSNYDYAFAFLISA 382 A + + + ++G G+ N+ G A ++PLVIG LVS +++ A F+ + Sbjct: 364 G-ALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCS 422 Query: 383 AIFSVVVSFFI 393 A+ ++V F+ Sbjct: 423 ALMAMVCYLFV 433 >ZyhaU [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 444 Score = 144 bits (363), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 121/431 (28%), Positives = 204/431 (47%), Gaps = 48/431 (11%) Query: 3 SAVQTRIYKYAVLALLYLGWCISYIDRAAITFAATHIASEFHLKPSDLGLLLSSFFLGYS 62 V TR Y +L ++++ ++Y DRA ++ A T +A E L +G + S+F Y Sbjct: 11 KGVHTR---YLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYL 67 Query: 63 LLQLPGGWLADRFGSRPVIVISILMWSLFTGLTG------MAWSITSLVVIRFFFGIGEG 116 L+Q+PGGWL D+FGS+ V S+ WSLFT L G +AW+ S+ +RF G E Sbjct: 68 LMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEA 127 Query: 117 -SFPAASIKGVAEHFDKGERPKMSSVLMSSNYIGSMLAPVIIAPLILHFGWRNVFHYIGI 175 SFPA + + VA F ER S++ S+ Y L ++ L +GW +VF +G+ Sbjct: 128 PSFPANA-RIVAAWFPTKERGTASAIFNSAQYFSLALFSPLLGWLTFAWGWEHVFTVMGV 186 Query: 176 VGIIFAVAYWLCVRPLSERTDGGKRPVNS-KTISE------------------------L 210 +G + A W ++ + TD + K ISE + Sbjct: 187 IGFVL-TALW--IKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKLHYI 243 Query: 211 MRLPLMWQLVAVWFGLSVVNK---GLDSWMPTYLMTVRGLDLKAVGLLLPLPYVMAGIST 267 +L ++ V+FG +N +W P YL+ +G+ + VGL+ +P + Sbjct: 244 KQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGG 303 Query: 268 AIGG----WLMMRFFN-GRERVMLVVSSALTAIFVYFMYVASDVTGVIIFQCLAYFFKSF 322 +GG +L+ R + R + +V L A + ++ T V++ LA+F K F Sbjct: 304 VLGGVFSDYLIKRGLSLTLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGF 363 Query: 323 VLAACFALPTKILDTRLIGSSVGMVNLGGQAAGFISPLVIGILVSAFSNYDYAFAFLISA 382 A + + + ++G G+ N+ G A ++PLVIG LVS +++ A F+ + Sbjct: 364 G-ALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPLVIGYLVSELHSFNAALVFVGCS 422 Query: 383 AIFSVVVSFFI 393 A+ ++V F+ Sbjct: 423 ALMAMVCYLFV 433