BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1084.p (454 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2518 [PR] COG4638 Phenylpropionate dioxygenase and related rin... 606 e-173 Cgl2352 [PR] COG4638 Phenylpropionate dioxygenase and related ri... 589 e-168 PA2512 [PR] COG4638 Phenylpropionate dioxygenase and related rin... 411 e-114 PA2083 [PR] COG4638 Phenylpropionate dioxygenase and related rin... 217 5e-56 hcaA1 [PR] COG4638 Phenylpropionate dioxygenase and related ring... 162 1e-39 >PA2518 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Pae Pseudomonas aeruginosa Length = 455 Score = 606 bits (1563), Expect = e-173, Method: Compositional matrix adjust. Identities = 277/437 (63%), Positives = 343/437 (78%), Gaps = 4/437 (0%) Query: 17 LETALEDNKEKGVFRCRRDIFTNPELFELEMKHIFESNWVYLAHESQIPNNNDYYTTWIG 76 L + LE++ E+GV+RC+R++FT+P LFELEMKHIFE NWVYLAHESQ+ NDY TT IG Sbjct: 8 LRSLLEEDPERGVYRCKREMFTDPRLFELEMKHIFEGNWVYLAHESQVAGVNDYLTTQIG 67 Query: 77 RQPVVITRDKNGELNALINACAHKGAMLCRRKHGNKSSFTCPFHGWTFSNSGKLLKVKDE 136 RQ +VI R+++G+LNA INAC+H+GAMLCR K GN+SS+TCPFHGWTF+NSGKLLKVKD Sbjct: 68 RQSIVIARNRDGQLNAFINACSHRGAMLCRHKSGNRSSYTCPFHGWTFNNSGKLLKVKDP 127 Query: 137 KNTEYPVSFNKDGSHDLTKVARFKSYRGFLFGSLNPDVLPLEEYLGETRVIIDQIVDQAP 196 YP FN +GSHDLT+VARF+SYRGFLFGSLNPDV PL E+LGE+ IID IVDQ+P Sbjct: 128 AEAGYPQGFNCEGSHDLTRVARFESYRGFLFGSLNPDVRPLAEHLGESAKIIDMIVDQSP 187 Query: 197 NGLEVLRGNSSYIYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRKEGGT----RATDAN 252 GLEVLRG+SSY+Y+GNWK+ ENG DGYHVS+VHWNYAAT +R++ R A Sbjct: 188 EGLEVLRGSSSYVYEGNWKLTAENGADGYHVSSVHWNYAATQSQRQQRDAADPLRTMSAA 247 Query: 253 NWSKAVAGVYGYENGHILLWTNTLNPEVRPIWNQREELAKRVGQERADIIVSQTRNLCIY 312 W++ G Y +E+GH+LLW+ NPE RP + +R ELA+ G+ RAD ++ +RNLC+Y Sbjct: 248 GWARQGGGFYSFEHGHMLLWSRWANPEDRPAFERRAELARDFGEARADWMIENSRNLCLY 307 Query: 313 PNVFLMDQFGTQIRVARPIGVDKTEISIFCFGPKGESAADRTTRIRQYEDFFNVSGMGTA 372 PNV+LMDQF +QIR+ARP+ VD+TEI+I+C PKGESA R RIRQYEDFFNVSGM T Sbjct: 308 PNVYLMDQFSSQIRIARPLSVDRTEITIYCIAPKGESAEARARRIRQYEDFFNVSGMATP 367 Query: 373 DDLEEFRACQAGYAGSAVRWNDMSRGAPLWIEGPDENAKKMGMKPLLSGERSEDEGLFIC 432 DDLEEFR+CQ GY GS V WND+SRGA WIEG D A + ++P LSG R+EDEGLF+ Sbjct: 368 DDLEEFRSCQQGYQGSVVGWNDLSRGAEHWIEGADAAAAAIDLRPRLSGVRTEDEGLFVL 427 Query: 433 QHHYWTKAMRKAIKEER 449 QH YW +A+ A++ ER Sbjct: 428 QHRYWQEALLAALERER 444 >Cgl2352 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Cgl Corynebacterium glutamicum Length = 497 Score = 589 bits (1519), Expect = e-168, Method: Compositional matrix adjust. Identities = 271/453 (59%), Positives = 341/453 (75%), Gaps = 7/453 (1%) Query: 1 MSTIAPIDKYNEVETLLETALEDNKEKGVFRCRRDIFTNPELFELEMKHIFESNWVYLAH 60 MST P+ V+ L+ ALED E+G+ R R+IFT+PE+FELEM+HIFE NW+YLAH Sbjct: 1 MST--PVSNLASVQKTLDHALEDRPEEGIVRVNRNIFTDPEIFELEMRHIFEGNWIYLAH 58 Query: 61 ESQIPNNNDYYTTWIGRQPVVITRDKNGELNALINACAHKGAMLCRRKHGNKSSFTCPFH 120 ESQIPN DY+TT+IGRQP++ITR K+G LN LINAC+H+GAMLCRRK N+++ TCPFH Sbjct: 59 ESQIPNAGDYFTTYIGRQPIMITRSKDGTLNCLINACSHRGAMLCRRKTDNRTTLTCPFH 118 Query: 121 GWTFSNSGKLLKVKDEKNTEYPVSFNKDGSHDLTKVARFKSYRGFLFGSLNPDVLPLEEY 180 GWTFSN G LLKVKDEK YP +F DGSHDL +V +F+SYRGFLFGSLN DV+ LEE+ Sbjct: 119 GWTFSNDGALLKVKDEKEGAYPENFRTDGSHDLRRVPKFESYRGFLFGSLNDDVVSLEEH 178 Query: 181 LGETRVIIDQIVDQAPNGLEVLRGNSSYIYDGNWKMQMENGCDGYHVSTVHWNYAATMGR 240 LG+TR +ID +VDQ+P GLEVLRG+S+Y YDGNWK+Q ENG DGYHVS+ HWNYAAT R Sbjct: 179 LGDTRTVIDMLVDQSPEGLEVLRGSSTYTYDGNWKLQTENGADGYHVSSTHWNYAATTSR 238 Query: 241 RKEG----GTRATDANNWSKAVAGVYGYENGHILLWTNTLNPEVRPIWNQREELAKRVGQ 296 R G T+A DA W K G + Y GH+LLW NPE RP++ +R+E K G+ Sbjct: 239 RGTGESANETKAMDAGTWGKQGGGYFSYPYGHMLLWMWWGNPEDRPLFERRDEFKKEFGE 298 Query: 297 ERADIIVSQTRNLCIYPNVFLMDQFGTQIRVARPIGVDKTEISIFCFGPKGESAADRTTR 356 E+ + +V +RNLC+YPNV+LMDQF +QIR RPI VD+TE++I+C PKGESA R R Sbjct: 299 EKGEFMVGASRNLCLYPNVYLMDQFSSQIRHIRPISVDQTEVTIYCIAPKGESAEARANR 358 Query: 357 IRQYEDFFNVSGMGTADDLEEFRACQAGYAGSAVRWNDMSRGAPLWIEGPDENAKKMGMK 416 IRQYEDFFN +GM T DDLEEFR+CQ Y SA WNDM+RG ++GP+E AK +GM Sbjct: 359 IRQYEDFFNATGMATPDDLEEFRSCQKTYQASAFPWNDMTRGLGHQVQGPNEVAKGLGMN 418 Query: 417 PLL-SGERSEDEGLFICQHHYWTKAMRKAIKEE 448 +L SG R+EDEGL+ QH +W + M++A+ ++ Sbjct: 419 EVLSSGARTEDEGLYPIQHGFWHELMQEAVNKQ 451 >PA2512 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Pae Pseudomonas aeruginosa Length = 464 Score = 411 bits (1057), Expect = e-114, Method: Compositional matrix adjust. Identities = 212/443 (47%), Positives = 294/443 (66%), Gaps = 25/443 (5%) Query: 21 LEDNKEKGVFRCRRDIFTNPELFELEMKHIFESNWVYLAHESQIPNNNDYYTTWIGRQPV 80 L+ E+G+FR RD+FT PELF+LEM+ IFE NW+Y HES++ +D+ T GRQP+ Sbjct: 19 LDFRPEEGIFRIARDMFTEPELFDLEMELIFEKNWIYACHESELARPHDFVTLRAGRQPL 78 Query: 81 VITRDKNGELNALINACAHKGAMLCRRKHGNKSSFTCPFHGWTFSNSGKLLKVKDEKNTE 140 ++TRD NG+L+AL+NAC H+GA L R GN+S+FTCPFH W + N G+L+KVK E Sbjct: 79 IVTRDGNGQLHALVNACQHRGATLVRVGKGNQSTFTCPFHAWCYKNDGRLVKVK--APGE 136 Query: 141 YPVSFNKDGSHDLTKVARFKSYRGFLFGSLNPDVL---PLEEYLGETRVIIDQIVDQAPN 197 YP F+K + L K AR +SYRGF+F SL DV L ++LG+ RV +D +V Q+P+ Sbjct: 137 YPEGFDK-ATRGLKK-ARIQSYRGFVFVSL--DVAGEDDLVDFLGDARVFLDMLVAQSPS 192 Query: 198 G-LEVLRGNSSYIYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRKE-----GGTRATDA 251 G LEVL G S+Y Y+GNWK+Q ENG DGYHVSTVH+NY AT+ R++ GG AT Sbjct: 193 GELEVLPGTSTYTYEGNWKLQNENGLDGYHVSTVHYNYVATVQHRQQVEAERGGVAAT-- 250 Query: 252 NNWSKAVAGV-------YGYENGHILLWTNTLNPEVRPIW-NQREELAKRVGQERADIIV 303 ++SK AG + + NGH +L++ NP VRP + + L GQ RA+ ++ Sbjct: 251 LDYSKLGAGDAATDDGWFSFANGHSVLFSEMPNPAVRPGYASVMPRLVAEYGQARAEWMM 310 Query: 304 SQTRNLCIYPNVFLMDQFGTQIRVARPIGVDKTEISIFCFGPKGESAADRTTRIRQYEDF 363 + RNL +YP++F++DQ +Q+R+ RP+ ++TEI C G KGES ADR RIRQ+EDF Sbjct: 311 HRLRNLNLYPSLFVIDQISSQLRIVRPLAWNRTEIVSQCIGVKGESDADRENRIRQFEDF 370 Query: 364 FNVSGMGTADDLEEFRACQAGYAGSAVRWNDMSRGAPLWIEGPDENAKKMGMKPLLSGER 423 FNVSGMGT DDL EFR Q G+ RW+D+SRG W+EG N++ +G+ PLL+G Sbjct: 371 FNVSGMGTPDDLVEFREAQRGFQARLERWSDISRGHGKWLEGATPNSQALGIAPLLTGTE 430 Query: 424 SEDEGLFICQHHYWTKAMRKAIK 446 EGL++ QH +W + + ++ Sbjct: 431 ITHEGLYVNQHAHWRRFLLDGLE 453 >PA2083 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Pae Pseudomonas aeruginosa Length = 424 Score = 217 bits (552), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 125/390 (32%), Positives = 193/390 (49%), Gaps = 24/390 (6%) Query: 23 DNKEKGVFRCRRDIFTNPELFELEMKHIFESNWVYLAHESQIPNNNDYYTTWIGRQPVVI 82 + + FR RR + + EL E+ IF+ +W+Y AH S++ D+ T +G + ++I Sbjct: 6 ETDDASYFRVRRQAYVSAELHRRELHEIFDDSWLYAAHLSELREPGDFITRDVGGRNLII 65 Query: 83 TRDKNGELNALINACAHKGAMLCRRKHGNKSSFTCPFHGWTFSNSGKLLKVKDEKNTEYP 142 R +GE +NACAH+GA +C + GN FTCP+HGWT+ + G L+ + D+ ++ Sbjct: 66 QRRADGEPAVYLNACAHRGAKVCAERQGNSQRFTCPYHGWTYDSHGSLIGLPDKAAYQHA 125 Query: 143 VSFNKDGSHDLTKVARFKSYRGFLFGSLNPDVLPLEEYLGETRVIIDQIVDQAPNGLEVL 202 + + S LT+V + YR FLF LE YLG+ + ID I DQ+ LE++ Sbjct: 126 GQCHPELS--LTQV-KHAVYRNFLFIHYGARQASLETYLGQAKDYIDLICDQSEAELEII 182 Query: 203 RGNSSYIYDGNWKMQMENGCDGYHVSTVHWNYAATMGRRKEGGTRATDANNWSKAVAGVY 262 G + NWK+ ENG D YH+ H Y + T TD + + G Sbjct: 183 PGGFEHSIKANWKLLAENGVDAYHLPFAHKRYLEYL------NTLGTDPESHKRHGRGE- 235 Query: 263 GYENGHILL-------------WTNTLNPEVRP-IWNQREELAKRVGQERADIIVSQTRN 308 NGH L+ W+ ++P I + E L +R GQ RA+ I ++ Sbjct: 236 ALGNGHALIISGPPSTGRPIAYWSPLFPEALKPSIAAKFERLVERFGQARAEDIAHTNKS 295 Query: 309 LCIYPNVFLMDQFGTQIRVARPIGVDKTEISIFCFGPKGESAADRTTRIRQYEDFFNVSG 368 L I+PN+ + D G IR P D+ ++++ G E+ +R RI F G Sbjct: 296 LFIFPNLVINDILGLNIRSFFPTAADEVSVTVWGAGFADETREERAARINGLISFIGPGG 355 Query: 369 MGTADDLEEFRACQAGYAGSAVRWNDMSRG 398 GT DD+E +CQ YA +A+ ++D SRG Sbjct: 356 FGTPDDVEILESCQRAYAHAALGYSDFSRG 385 >hcaA1 [PR] COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Eco Escherichia coli K12 Length = 453 Score = 162 bits (411), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 107/373 (28%), Positives = 175/373 (46%), Gaps = 25/373 (6%) Query: 36 IFTNPELFELEMKHIFESNWVYLAHESQIPNNNDYYTTWIGRQPVVITRDKNGELNALIN 95 I+T+P++++LE++ IF W++LAHESQIP D++ T++G VV+ R K+G + A +N Sbjct: 24 IYTDPDIYQLELERIFGRCWLFLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLN 83 Query: 96 ACAHKGAMLCRRKHGNKSSFTCPFHGWTFSNSGKLLKVKDEKNTEYPVSFNKDGSH-DLT 154 C H+ + GN +FTCP+HGW++ +G+L+ V E YP K SH L Sbjct: 84 QCRHRAMRVSYADCGNTRAFTCPYHGWSYGINGELIDVPLEPRA-YPQGLCK--SHWGLN 140 Query: 155 KVARFKSYRGFLFGSLNPDVLPLEEYLGETRVIIDQIVDQAPNGLEVLRGNSSYIYDGNW 214 +V +SY+G +FG+ + L +YLG+ +D ++D+ G E++ G ++ + NW Sbjct: 141 EVPCVESYKGLIFGNWDTSAPGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNW 200 Query: 215 KMQMEN-GCDGYHVSTVHWNYAATMGRRKEG-----GTRATDANNWSKAVAGVYGYENGH 268 K E D YH H + +G + +G G T W A + ++GH Sbjct: 201 KFPAEQFASDQYHALFSHASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGH 260 Query: 269 ILLWTNTLNPEVRPIW----------NQREELAKRVGQERADIIVSQTRNLCIYPNVFLM 318 + T P+ +W E +R+G+ RA + I+P + + Sbjct: 261 GSGFFFTEKPDAN-VWVDGAVSSYYRETYAEAEQRLGEVRALRLAGHNN---IFPTLSWL 316 Query: 319 DQFGTQIRVARPIGVDKTEISIFCFGPKGESAADRTTRIRQYEDFFNVSGMGTADDLEEF 378 + T +RV P G D+ E+ FC K S + F +G DD E + Sbjct: 317 NGTAT-LRVWHPRGPDQVEVWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENW 375 Query: 379 RACQAGYAGSAVR 391 Q G R Sbjct: 376 CEIQKLLKGHRAR 388