BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1048.p (312 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc2648 [GER] COG0697 Permeases of the drug/metabolite transport... 345 1e-94 CC0848 [GER] COG0697 Permeases of the drug/metabolite transporte... 236 5e-62 RSc0233 [GER] COG0697 Permeases of the drug/metabolite transport... 226 6e-59 RSc1428 [GER] COG0697 Permeases of the drug/metabolite transport... 203 5e-52 STM4400 [GER] COG0697 Permeases of the drug/metabolite transport... 150 5e-36 >AGc2648 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 310 Score = 345 bits (884), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 171/306 (55%), Positives = 223/306 (72%) Query: 3 SNPILQGMFYSALAGAAWGLVFLAPELTRAFSPWQLTAGRYLAYGLFAALLIAPRIKKLL 62 +N G+FY LAGA WG +FLAP+L FS QL+ RYL YGL + ++I PR+K++ Sbjct: 2 NNRTGLGVFYGMLAGALWGGIFLAPKLVPDFSALQLSTARYLTYGLISLIIIGPRLKRVS 61 Query: 63 PHLGRAEWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAV 122 H G EW AL WLS++GN+ YYVF+++AV+L G+A TS++IGFLPVAV+IIGSR HGAV Sbjct: 62 AHFGAREWIALGWLSMIGNIAYYVFISTAVKLSGVAFTSIIIGFLPVAVTIIGSRDHGAV 121 Query: 123 PLRKLAPSLALGLAGIACVAWQSLAGSATGDMKESVIGFFCALAALASWTTYAVGNSRWL 182 L++L PSLA G GI ++WQSL + G +IG AL ALASWT +AVGN+RWL Sbjct: 122 SLKRLWPSLAFGAIGIVGISWQSLTENDAGLDVSRLIGLASALGALASWTAFAVGNARWL 181 Query: 183 ARLHEVSAHDWNLLIGVVTGLLSLFIAVPAFTVKLQPHPGSQWLHFVVVSAGVAIFASLF 242 +RLH+VSA DWN++ GVVTG L+L +A+PAF + H WLHF ++AG+ AS+ Sbjct: 182 SRLHDVSADDWNMMTGVVTGGLALLLAIPAFGFGGESHSSGDWLHFAAIAAGLGFTASIL 241 Query: 243 GNACWNKATRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTGSVLLCVS 302 GNA WN+ +R+LPLTM+GQMILFETLFALLYGFLWE PT +EI A+ V SV+LC+ Sbjct: 242 GNAFWNRMSRMLPLTMVGQMILFETLFALLYGFLWEGHGPTFVEIVAICSVVLSVVLCMR 301 Query: 303 AHRVDE 308 AHR ++ Sbjct: 302 AHRPEK 307 >CC0848 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ccr Caulobacter vibrioides Length = 312 Score = 236 bits (602), Expect = 5e-62, Method: Compositional matrix adjust. Identities = 149/291 (51%), Positives = 193/291 (66%) Query: 15 LAGAAWGLVFLAPELTRAFSPWQLTAGRYLAYGLFAALLIAPRIKKLLPHLGRAEWRALV 74 +AGA WG VFLAP+L F+P Q TAGRYLAYGL AA+L+AP K ++ + +WR L+ Sbjct: 16 IAGAFWGGVFLAPKLLADFTPLQATAGRYLAYGLAAAVLLAPSWKAVMARMDGRDWRDLL 75 Query: 75 WLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVPLRKLAPSLALG 134 LSLLGN++YYV LA AVQ G+A+ SLVIG LPV ++++G++ PLR+L LAL Sbjct: 76 LLSLLGNLIYYVGLAIAVQSAGVALASLVIGLLPVTITLVGAKAGEGTPLRRLVWPLALI 135 Query: 135 LAGIACVAWQSLAGSATGDMKESVIGFFCALAALASWTTYAVGNSRWLARLHEVSAHDWN 194 +AG C+ + A + M ++++G AL ALA WT YAV N+R LA + ++H+W+ Sbjct: 136 VAGGVCINLDAFAAAGRAGMSKTLVGLLGALLALAVWTAYAVWNARRLAATPKFNSHEWS 195 Query: 195 LLIGVVTGLLSLFIAVPAFTVKLQPHPGSQWLHFVVVSAGVAIFASLFGNACWNKATRLL 254 LL GV TGLLSL I VPAF + H W F VS VAI AS+ GN WN A+RLL Sbjct: 196 LLTGVATGLLSLVIVVPAFAFDGKTHAAGAWGLFWGVSFAVAIGASVIGNGLWNAASRLL 255 Query: 255 PLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTGSVLLCVSAHR 305 PL++ GQ+I+FET+FALLYGFL E RWP LE AM L+ VL HR Sbjct: 256 PLSLSGQLIVFETVFALLYGFLHEGRWPRSLESVAMALMLAGVLWSARLHR 306 >RSc0233 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 326 Score = 226 bits (575), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 139/302 (46%), Positives = 190/302 (62%), Gaps = 4/302 (1%) Query: 7 LQGMFYSALAGAAWGLVFLAPELTRAFSPWQLTAGRYLAYGLFAALLIAPRIKKLLPHLG 66 L G+ AGA WG++F+AP + AFSP L+A RYL YG+ + L P + L Sbjct: 24 LTGLGCGIAAGALWGIIFVAPRMLPAFSPLALSAARYLLYGVLSLALALPVWRPLWRKTT 83 Query: 67 RAEWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVPLRK 126 R +W ALV LSL GNV+YY+ +A VQ G+A SL++G LPV V++ G+ HG++PLR+ Sbjct: 84 RRDWLALVLLSLPGNVLYYLCVAGGVQRAGVAPVSLIVGLLPVTVTLAGAAEHGSLPLRR 143 Query: 127 LAPSLALGLAGIACVAWQSLAGSATGDMKESVIGFFCALAALASWTTYAVGNSRWLARLH 186 LA L + AG+AC+ + A A ++G A ALA WT YAV N+R+L R Sbjct: 144 LALPLLMAAAGVACIYADAPATQAGAGGATHLLGLLMAAGALACWTVYAVCNARYLRRHP 203 Query: 187 EVSAHDWNLLIGVVTGLLSLFIAVPAFTV----KLQPHPGSQWLHFVVVSAGVAIFASLF 242 + ++ +W+LL G+ TG LSL +AVPAF + P P S W F +V+ GVA+ AS+ Sbjct: 204 QFTSREWSLLTGIATGALSLVLAVPAFLMPGMATAAPQPASAWGLFWLVNTGVALGASVL 263 Query: 243 GNACWNKATRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTGSVLLCVS 302 GN+ WN A+R LPLT+ GQMI+FET+FALLYGF+ E RWP LE+AA +L+ V L Sbjct: 264 GNSLWNTASRKLPLTLSGQMIVFETVFALLYGFIQEGRWPHGLEVAAALLLMSGVGLAAR 323 Query: 303 AH 304 H Sbjct: 324 RH 325 >RSc1428 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 203 bits (516), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 143/308 (46%), Positives = 183/308 (59%), Gaps = 8/308 (2%) Query: 9 GMFYSALAGAAWGLVFLAPELTRAFSPWQLTAGRYLAYGLFAALLIAPRIKKLLPHLGRA 68 G+ + LAGA WG+VF+AP AFSPW+L GRYLAYG AAL AP + ++ L RA Sbjct: 4 GVLCALLAGAMWGMVFIAPRALPAFSPWELALGRYLAYGAIAALAAAPILPRIARKLTRA 63 Query: 69 EWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAVSIIGSRGHGAVPLRKLA 128 + AL+ + GN+VYYV LA VQL G+A SL+IG LP+ V+++G R HGAVPL +LA Sbjct: 64 DCLALMRQACSGNLVYYVLLAFGVQLAGVAPVSLIIGVLPITVTVLGRRDHGAVPLSRLA 123 Query: 129 PSLALGLAGIACVAWQ--SLAGSATGDMK---ESVIGFFCALAALASWTTYAVGNSRWLA 183 L + AGIAC+ S A GD + G CA AL SWT YA+ N+R L Sbjct: 124 WPLLVVAAGIACINIDLFSHDAVAAGDAHPIWSRIAGIACAAGALCSWTWYAIDNARHLQ 183 Query: 184 RLHEVSAHDWNLLIGVVTGLLSLFIAVPAFTVKLQ---PHPGSQWLHFVVVSAGVAIFAS 240 R S+++W+ L G+ TG LS + A G W F V+A VA+ AS Sbjct: 184 RNPHFSSNEWSALYGISTGALSAALTAAAVLAAGTGWAEGGGRVWTTFWAVNAAVALGAS 243 Query: 241 LFGNACWNKATRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIAAMVLVTGSVLLC 300 L GN WN A R LPLT+ GQMI+FETLFAL YGF+++ RWP LE+AA+ L+ V Sbjct: 244 LIGNNLWNIAARRLPLTLSGQMIVFETLFALAYGFVYDHRWPRPLEMAAIALLIVGVGWS 303 Query: 301 VSAHRVDE 308 V H D Sbjct: 304 VRLHADDN 311 >STM4400 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sty Salmonella typhimurium LT2 Length = 321 Score = 150 bits (378), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 109/316 (34%), Positives = 164/316 (51%), Gaps = 24/316 (7%) Query: 6 ILQGMFYSALAGAAWGLVFLAPELTRAFSPWQLTAGRYLAYGLFAALLIAPRIKKLLPHL 65 ++ G+ Y+ LAG WGL+F+ P + + + GRYLA GL A L IA + L L Sbjct: 1 MISGVLYALLAGLMWGLIFVGPLIVPDYPALLQSMGRYLALGLIA-LPIAWLGRTRLRQL 59 Query: 66 GRAEWRALVWLSLLGNVVYYVFLASAVQLGGMAMTSLVIGFLPVAV----SIIGSRGHGA 121 R +W + L+L+GNV+YY LASA+Q G +++++IG LPV + +++ S+ G Sbjct: 60 TRKDWSTALSLTLMGNVIYYACLASAIQRTGAPVSTMIIGTLPVVIPLFANVLYSQRDGR 119 Query: 122 VPLRKLAPSLALGLAGIACVAWQSLA---GSATGDMKESVIGFFCALAALASWTTYAVGN 178 + R+LAP+LAL G+ CV L+ +G S G AL ++A W YA+ N Sbjct: 120 LSWRRLAPALALIGFGLLCVNIAELSQGLSDVSGWRYGS--GIVLALISVACWAWYALRN 177 Query: 179 SRWLARLHEVSAHDWNL----------LIGVVTGLLSLFIAVPAFTVKLQPHPGSQWLHF 228 +RWL + W LIG L L I P FT+ PHP F Sbjct: 178 ARWLRENPDKHPMMWATAQALVTLPVSLIGYAAVCLWLSIQKPLFTLPFGPHPA----LF 233 Query: 229 VVVSAGVAIFASLFGNACWNKATRLLPLTMIGQMILFETLFALLYGFLWEQRWPTLLEIA 288 + + +A+ S G CWN A++ LP ++G +I+FETL LLY F+ Q P L ++ Sbjct: 234 IGLMIAIAVLCSWVGALCWNIASQKLPTVILGPLIVFETLAGLLYTFILRQEIPPFLTLS 293 Query: 289 AMVLVTGSVLLCVSAH 304 + L+ V++ V A Sbjct: 294 GIALLVAGVVIAVRAK 309