BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.1040.p (322 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value VCA0034 [T] COG1639 Predicted signal transduction protein Vch Vi... 85 3e-16 TM0854 [T] COG1639 Predicted signal transduction protein Tma The... 68 2e-11 PA5346_2 [T] COG1639 Predicted signal transduction protein Pae P... 57 4e-08 PA0356 [T] COG1639 Predicted signal transduction protein Pae Pse... 49 2e-05 TP0073 Non COG 47 5e-05 >VCA0034 [T] COG1639 Predicted signal transduction protein Vch Vibrio cholerae Length = 290 Score = 84.7 bits (208), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 63/236 (26%), Positives = 112/236 (47%), Gaps = 14/236 (5%) Query: 3 LTFIEPTLFEKLRSAQALPSPGGVRLTIMRMCAQDDPDMAELIHLVQADPALSGRIIRIV 62 + ++ T+ +L LP V ++ M Q D D +L + D L+ R++R+ Sbjct: 13 MNMVKNTMLNRLNE---LPRLSKVLQELLDMANQPDVDFHQLSKKITLDQILTARLLRMA 69 Query: 63 NVLNAERVRPIASVSMDSMLLVGLQAVRQLALALSLAETTAPASCTNFKLPAFWAHSFAM 122 N IA+V+ D+++ VG+++VR L +A S+ +T P T L +W ++F Sbjct: 70 NSAYFGGNGHIATVN-DAIIRVGIESVRTLVVA-SVLSSTFPKIET-LDLNDYWTNTFET 126 Query: 123 ACGAQAISGHTRVAPLGEMFTTGLLANIGKLTLASAHPSAYSSLLTRPLDASTQLTMEQS 182 A A I+ + E FTTG+L NIG+L + + P+ S + + L+ ++ Sbjct: 127 ALIASKIAEQVGLDK-SETFTTGVLHNIGELMIHTLMPTEASLIQQKIAQGMDPLSAQEE 185 Query: 183 LFGFNHLNIAAALMQDWKIPELFCDAVLHYEAPVPSEELPA-------PRSVEITW 231 + G + I A L ++WK P DA+ H++ P +E P R + +W Sbjct: 186 VLGISAPRIGAMLAKEWKFPSEMVDAIKHFDEPREAEISPKLAVAIHFARDINFSW 241 >TM0854 [T] COG1639 Predicted signal transduction protein Tma Thermotoga maritima Length = 285 Score = 68.2 bits (165), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 63/283 (22%), Positives = 121/283 (42%), Gaps = 25/283 (8%) Query: 20 LPSPGGVRLTIMRMCAQDDPDMAELIHLVQADPALSGRIIRIVNVLNAERVRPIASVSMD 79 LPSP V I+ +C++ D E+ + + D +LS R++++ N R I ++S + Sbjct: 16 LPSPNVVVQRIIAVCSKPDASSTEVANTLMMDASLSARVLKLANSAYYGVPRKITTLS-E 74 Query: 80 SMLLVGLQAVRQLALALSLAETTAPASCTNFKLPAFWAHSFAMACGAQAISGHTRVAPLG 139 +++++G + VR LAL++ + S + W H A A ++ ++ T PL Sbjct: 75 AVMILGFKTVRNLALSVFTYDMVFKNSSSGIDREKLWEHFIASAIASETVA-ETMGYPLK 133 Query: 140 -EMFTTGLLANIGKLTLASAHPSAYSSLLTRPLDASTQ---------LTMEQSLFGFNHL 189 E+F GLL ++GK+ Y L + L+ + + +E+ L H Sbjct: 134 EEIFIAGLLHDLGKVV--------YDLLFSDILETEAKIAQKTKKNLIDIEEELGIPPHS 185 Query: 190 NIAAALMQDWKIPELFC-DAVLHYEAPVPSEELPAPRSVEITWTLYLATAMAELGCAAPP 248 + A L++ W P+L A H+ E P V +++ +A L Sbjct: 186 EVGAKLLRKWNFPDLLVLSAEFHHNV----EGNPNELFVNQVSMVHIGDVIANLMMKGAS 241 Query: 249 VAEAALHKVARALPQLQLAPHDFPELYQQAGEDWQDWTQTMHI 291 ++ AL L++ P F + ++ E + + + I Sbjct: 242 LSWGDPKLSPFALNVLKVKPKTFLRILDKSKEKYNKAQEFLQI 284 >PA5346_2 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 293 Score = 57.4 bits (137), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 83/187 (44%), Gaps = 14/187 (7%) Query: 30 IMRMCAQDDPDMAELIHLVQADPALSGRIIRIVNVLNAERVRPIASVSMDSMLLVGLQAV 89 I+++ + + ++ LV+ DPAL+ +++ I SV + ++G V Sbjct: 29 IIKLRVDPNASVDDITGLVETDPALAAQVVSWAASPYYAAPGKIRSVEDAIVRVLGFDLV 88 Query: 90 RQLALALSLAETTAPASCTNFKLPAFWAHSFAMACGAQAISGHTRVAPL------GEMFT 143 LAL L+L ++ + + +W + A I G TR P G + Sbjct: 89 INLALGLALGKSLSLPKDQPQQATPYWQQAIYTAA---VIEGLTRAMPRELRPESGLSYL 145 Query: 144 TGLLANIGKLTLASAHPSAYSSLLTRPLDASTQL---TMEQSLFGFNHLNIAAALMQDWK 200 GLL N G L LA P +S L+ R L+ + L +EQ L G I A LM+ W Sbjct: 146 GGLLHNFGYLVLAHVFPPHFS-LICRHLEVNPHLGHAYIEQHLLGITREQIGAWLMRVWD 204 Query: 201 IP-ELFC 206 +P +L+C Sbjct: 205 MPDDLYC 211 >PA0356 [T] COG1639 Predicted signal transduction protein Pae Pseudomonas aeruginosa Length = 274 Score = 48.5 bits (114), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 49/218 (22%), Positives = 92/218 (42%), Gaps = 13/218 (5%) Query: 38 DPDMAELIHLVQADPALSGRIIRIVNVLNAERVRPIASVSMDSMLLVGLQAVRQLALALS 97 +PD+ + L+ DP LSG ++++VN I S+ ++ L+G ++V L A S Sbjct: 19 NPDLKNIARLISQDPGLSGALLKLVNSPFFGLANRITSIQR-AVNLLGSRSVINLINAQS 77 Query: 98 LAETTAPASCTNFKLPAFW--AHSFAMACGAQAISGHTRVAPLGEMFTTGLLANIGKLTL 155 + + + L FW A AM+C +++ + E + GL N G + Sbjct: 78 IKGEMSDDTIV--TLNRFWDTAQDVAMSC--LSLAKRIGYESVDEAYALGLFHNCGIPLM 133 Query: 156 ASAHPSAYSSLLTRPLDASTQ----LTMEQSLFGFNHLNIAAALMQDWKIPELFCDAVLH 211 P Y ++L A++ + E + NH + + W++PE C+A+ + Sbjct: 134 LKRFPH-YMAVLEEAYAAASDERRVVDTENRVLNTNHAVVGYYTARSWRLPEHVCEAIAN 192 Query: 212 YEAPVPSEELPAPRSVEITWTLYLATAMAELGCAAPPV 249 + + + R ++ L MAE C + V Sbjct: 193 HHNALSIFGDESARDTQLK-NLLAILKMAEHICGSHRV 229 >TP0073 Non COG Length = 513 Score = 47.0 bits (110), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 45/203 (22%), Positives = 85/203 (41%), Gaps = 21/203 (10%) Query: 28 LTIMRMCAQDDPDMAELIHLVQADPALSGRIIRIVNVLNAERVRPIASVSMDSMLLVGLQ 87 L I R D +++++ L+ D AL ++++VN + +S +++ VGL+ Sbjct: 262 LEIQRAIENPDVQLSDIVALISQDVALVTDLLKLVNSARFGMNKRCLDIS-EAVKRVGLR 320 Query: 88 AVRQLALALSLAETTAPASCTNFKL------PAFWAHSFAMACGAQAISGHTRVAPLGEM 141 ++ L ++ +L ++A A A G QA+ + + Sbjct: 321 GLQNLLYSVGAGRVLQSTDDERKQLWNQAYRTGYFALGLAKATGDQAL--------IADS 372 Query: 142 FTTGLLANIGKLTLASAHPSAYSSLLTRPLDASTQL---TMEQSLFGFNHLNIAAALMQD 198 + GLL N+G++ SA+P L + A + ++ + H I AAL Q Sbjct: 373 YICGLLHNLGEVVFTSAYPEMLIKLT--EIQAERNIPPHVLDTIMSDVGHAEIGAALAQR 430 Query: 199 WKIPELFCDAV-LHYEAPVPSEE 220 W +PE + + H+ P EE Sbjct: 431 WNLPEPVINTIRFHHNLPHAPEE 453