BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0978.p (203 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2454 [F] COG0299 Folate-dependent phosphoribosylglycinamide f... 296 2e-80 VC2227 [F] COG0299 Folate-dependent phosphoribosylglycinamide fo... 230 2e-60 YPO2829 [F] COG0299 Folate-dependent phosphoribosylglycinamide f... 222 5e-58 NMA1755 [F] COG0299 Folate-dependent phosphoribosylglycinamide f... 222 5e-58 PA0944 [F] COG0299 Folate-dependent phosphoribosylglycinamide fo... 219 3e-57 >RSc2454 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN Rso Ralstonia solanacearum Length = 216 Score = 296 bits (757), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 147/202 (72%), Positives = 167/202 (82%) Query: 1 MRSIVILISGRGSNMEAIVRAAQAERWPARIAAVISNRADASGLEFAASHGIATAVIANR 60 M++IVILISGRGSNMEAIVRA QAE WP RIAAVISNR DA+GL FAASHGIATAV+ ++ Sbjct: 1 MKNIVILISGRGSNMEAIVRACQAEGWPGRIAAVISNRPDAAGLRFAASHGIATAVVDHK 60 Query: 61 DYPTRDQFDAALRAQIDTFAPDLVVLAGFMRILTAPFVNHYQGRMLNIHPSLLPSFPGLA 120 +P RD FD AL A ID FAPDLVVLAGFMRILT FV Y GR+LNIHPSLLP FPGL Sbjct: 61 AFPDRDSFDTALAAAIDGFAPDLVVLAGFMRILTPGFVQRYAGRLLNIHPSLLPCFPGLH 120 Query: 121 THRQALAAGVKLHGATVHFVTPDLDHGPIVAQAAVPVLEDDSEETLAERVLEQEHVIYPR 180 TH QALA GVK+HGATVHFVT +LDHGPIV QAA+ V D+ ++LA R+LEQEHVIYPR Sbjct: 121 THEQALAMGVKVHGATVHFVTAELDHGPIVLQAAIEVRAGDTPDSLAARLLEQEHVIYPR 180 Query: 181 AVRWFVQGRLALDGARVRLAAE 202 AVRWFV+GRL ++ VR++ E Sbjct: 181 AVRWFVEGRLQMERGVVRVSPE 202 >VC2227 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN Vch Vibrio cholerae Length = 212 Score = 230 bits (586), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 110/202 (54%), Positives = 141/202 (69%) Query: 1 MRSIVILISGRGSNMEAIVRAAQAERWPARIAAVISNRADASGLEFAASHGIATAVIANR 60 M+SIV+LISG G+N++AI+ A ++ AV SN+A A GLE A G A I + Sbjct: 1 MKSIVVLISGNGTNLQAIIDACATSIQDGKVTAVFSNKATAYGLERAKQAGAAACFIDPK 60 Query: 61 DYPTRDQFDAALRAQIDTFAPDLVVLAGFMRILTAPFVNHYQGRMLNIHPSLLPSFPGLA 120 Y TRD FDAAL Q+D FAPDLVVLAG+MRIL++ FV HY GRM+NIHPSLLP +PGL Sbjct: 61 AYETRDAFDAALMEQMDKFAPDLVVLAGYMRILSSEFVRHYLGRMINIHPSLLPKYPGLN 120 Query: 121 THRQALAAGVKLHGATVHFVTPDLDHGPIVAQAAVPVLEDDSEETLAERVLEQEHVIYPR 180 T+++A+ AG + HG +VHFVT LD GP++ QA VP+ EDD+ E L RV +QEH IYP Sbjct: 121 TYQRAIHAGDEEHGTSVHFVTEQLDGGPVILQAKVPIFEDDTVEELTARVQDQEHRIYPL 180 Query: 181 AVRWFVQGRLALDGARVRLAAE 202 V+WFV+ RLA+ + L E Sbjct: 181 VVKWFVEERLAMKDGKAYLDGE 202 >YPO2829 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN Ype Yersinia pestis Length = 212 Score = 222 bits (565), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 113/206 (54%), Positives = 138/206 (66%), Gaps = 7/206 (3%) Query: 1 MRSIVILISGRGSNMEAIVRAAQAERWPARIAAVISNRADASGLEFAASHGIATAVIANR 60 M+ IV+LISG+GSN++A++ A Q R +I+AV SN A GLE A S GI + + Sbjct: 1 MKKIVVLISGQGSNLQALIDAQQQGRISGKISAVFSNNPAAYGLERAESAGIPHHALDAK 60 Query: 61 DYPTRDQFDAALRAQIDTFAPDLVVLAGFMRILTAPFVNHYQGRMLNIHPSLLPSFPGLA 120 + R FD AL ID + PDL+VLAG+MRIL+ FV HY GRMLNIHPSLLP +PGL Sbjct: 61 AFTDRVSFDLALAQAIDQYQPDLLVLAGYMRILSPEFVKHYAGRMLNIHPSLLPKYPGLH 120 Query: 121 THRQALAAGVKLHGATVHFVTPDLDHGPIVAQAAVPVLEDDSEETLAERVLEQEHVIYPR 180 THRQAL G + HG +VHFVT +LD GP++ QA VP+ DDSEE +AERV QEH IYP Sbjct: 121 THRQALENGDQEHGTSVHFVTEELDGGPVILQAKVPIFSDDSEEDVAERVQTQEHSIYPL 180 Query: 181 AVRWFVQGRLA-------LDGARVRL 199 V WF GRLA LDG R+ L Sbjct: 181 VVSWFTDGRLAMRDNAAWLDGVRLPL 206 >NMA1755 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN NmA Neisseria meningitidis Z2491 Length = 208 Score = 222 bits (565), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 110/198 (55%), Positives = 145/198 (73%), Gaps = 3/198 (1%) Query: 1 MRSIVILISGRGSNMEAIVRAAQAERWPARIAAVISNRADASGLEFAASHGIATAVIANR 60 M++IVILISGRGSNM+AIV AA RIAAV+SN A+GL++AA GI T + ++ Sbjct: 1 MKNIVILISGRGSNMQAIVNAAIPN---VRIAAVLSNSETAAGLQWAAGQGIPTDSLNHK 57 Query: 61 DYPTRDQFDAALRAQIDTFAPDLVVLAGFMRILTAPFVNHYQGRMLNIHPSLLPSFPGLA 120 ++ +R FD A+ +ID + PDLVVLAGFMRILT F HY+GR++NIHPS+LPSF GL Sbjct: 58 NFESRLAFDTAMMEKIDAYQPDLVVLAGFMRILTPEFCAHYEGRLMNIHPSVLPSFTGLH 117 Query: 121 THRQALAAGVKLHGATVHFVTPDLDHGPIVAQAAVPVLEDDSEETLAERVLEQEHVIYPR 180 TH +AL AG ++ G T+HFVT +LD GPIV+Q VP+L+ D+ + +A RVL EH +YP+ Sbjct: 118 THERALEAGCRVAGCTIHFVTAELDCGPIVSQGIVPILDGDTADDVAARVLAVEHKLYPK 177 Query: 181 AVRWFVQGRLALDGARVR 198 AV F GRL ++G RVR Sbjct: 178 AVADFAAGRLIIEGNRVR 195 >PA0944 [F] COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN Pae Pseudomonas aeruginosa Length = 222 Score = 219 bits (559), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 110/190 (57%), Positives = 138/190 (72%) Query: 3 SIVILISGRGSNMEAIVRAAQAERWPARIAAVISNRADASGLEFAASHGIATAVIANRDY 62 ++V+LISG GSN++A++ + + PARI AVISNRADA GLE A GI T V+ ++ Y Sbjct: 6 NVVVLISGSGSNLQALIDSLRDGATPARIRAVISNRADAYGLERARQAGIQTEVLDHKAY 65 Query: 63 PTRDQFDAALRAQIDTFAPDLVVLAGFMRILTAPFVNHYQGRMLNIHPSLLPSFPGLATH 122 R+ FD AL +ID P LV+LAGFMRIL+A FV HYQGR+LNIHPSLLP GL TH Sbjct: 66 ADRESFDEALAQRIDAHEPHLVILAGFMRILSADFVRHYQGRLLNIHPSLLPRHKGLHTH 125 Query: 123 RQALAAGVKLHGATVHFVTPDLDHGPIVAQAAVPVLEDDSEETLAERVLEQEHVIYPRAV 182 ++AL AG + HG +VHFVT +LD GP+V QA +PV D+ E LA RV E+EH IYP A+ Sbjct: 126 QRALEAGDREHGCSVHFVTEELDGGPLVVQAVIPVESQDTPERLARRVHEEEHRIYPLAM 185 Query: 183 RWFVQGRLAL 192 RWF +GRL L Sbjct: 186 RWFAEGRLRL 195