BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0927.p (493 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1611 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ra... 588 e-168 CC3140 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 554 e-157 gabD [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Esche... 543 e-154 ZgabD [C] COG1012 NAD-dependent aldehyde dehydrogenases EcZ Esch... 542 e-154 ECs3522 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ecs Es... 542 e-154 >RSp1611 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ralstonia solanacearum Length = 493 Score = 588 bits (1517), Expect = e-168, Method: Compositional matrix adjust. Identities = 327/489 (66%), Positives = 379/489 (77%), Gaps = 3/489 (0%) Query: 5 ELQRPDLMPGTQLIGAQWRAAADGRVLEVSNPATGQVFATVPDGNAEDARAAVDAAVAAF 64 +L+ L+ LI +W A ADG V++PATG + A V D +A DARAA DAA A Sbjct: 7 QLRHTGLIRTDNLIDGRWSAGADGARYAVTDPATGSIIAQVADSSAADARAATDAAARAL 66 Query: 65 PAWRATPAKQRATIIKRWNDLLLAHQEDLGRLISREQGKPLAEAKGEVAYAASYVEWFGE 124 PAWR T +RA I++RW+ ++A+ + LGRLIS EQGKP AE +GEV Y ASYV WF + Sbjct: 67 PAWRDTLPAERAAILRRWHAAIVANADALGRLISLEQGKPFAEGRGEVMYGASYVAWFAD 126 Query: 125 EATRANGDIIPAPVTGRRMMALKEPVGVVAAITPWNFPAAMIARKIAPALAAGCTVVCKP 184 EATR GD+IP G+RM A+KEP+G+VAAITPWNFP AMIARKIAPALAAGCTVV KP Sbjct: 127 EATRIYGDLIPQQQRGKRMSAIKEPIGIVAAITPWNFPLAMIARKIAPALAAGCTVVAKP 186 Query: 185 AEDTPLTSLAIIRLALEAGVPAGVINIVTASRERTPEVVDVWLADSRVRKISFTGSTAVG 244 AEDTPLT+LA+ +LA EAG+P GV+N++ ASRER V WL D RVRKI+FTGST VG Sbjct: 187 AEDTPLTALALAQLAQEAGLPPGVLNMIAASRERGVAAVADWLQDGRVRKITFTGSTPVG 246 Query: 245 KHLARHSADTLKKLSLELGGNAPFIVFDDADLDAAIDGVMAAKFRNGGQTCVSPNRIYVQ 304 KHLAR SA TLKKLSLELGGNAPFIVFDDADLDAAI G+++AKFRNGGQTCV PNR+YVQ Sbjct: 247 KHLARESAGTLKKLSLELGGNAPFIVFDDADLDAAIAGLLSAKFRNGGQTCVCPNRVYVQ 306 Query: 305 EKVYDAFVAKLGARVAALKVGPATDPASQIGPMINARAIAKIDQHVRDAIERGARVITGG 364 VYD F A L ARV+ALKV PATDP +QIGPMINARA+ KI++HV+DA+ GARV+ GG Sbjct: 307 AGVYDRFAAMLAARVSALKVAPATDPDAQIGPMINARAVDKIERHVQDAVAHGARVLAGG 366 Query: 365 KRLQGPGFDSDNYYAPTVLANVTGQMQCSCEETFGPVAPVTRFATEEEVVTAANATPFGL 424 KRL G ++YAPTVLA+ M EETFGPV P+ RF E E V AAN TPFGL Sbjct: 367 KRLPEVG---AHFYAPTVLADAHPGMALCGEETFGPVVPLFRFTDEAEAVQAANDTPFGL 423 Query: 425 AAYFYSTDVRRIHRVTDALESGIVGVNEGALAAEAAPFGGVKESGYGREGSVHGLDDYLH 484 AAYFYS DVRRI RV ALE+GIVG+NEGALA+EAAPFGGVKESGYGREGS +GLDDYL Sbjct: 424 AAYFYSQDVRRIDRVAHALEAGIVGINEGALASEAAPFGGVKESGYGREGSKYGLDDYLS 483 Query: 485 TKYVCQGQL 493 KY+CQG L Sbjct: 484 IKYLCQGGL 492 >CC3140 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 482 Score = 554 bits (1428), Expect = e-157, Method: Compositional matrix adjust. Identities = 283/483 (58%), Positives = 351/483 (72%), Gaps = 10/483 (2%) Query: 10 DLMPGTQLIGAQW-RAAADGRVLEVSNPATGQVFATVPDGNAEDARAAVDAAVAAFPAWR 68 +L+ LI QW R A +V NPA G + A V D A + A+DAA A PAW Sbjct: 5 NLVETAALIDGQWVRGEAS---FDVLNPADGTLIAAVADLGAAETTLAIDAAHRALPAWA 61 Query: 69 ATPAKQRATIIKRWNDLLLAHQEDLGRLISREQGKPLAEAKGEVAYAASYVEWFGEEATR 128 A AK+R I++RW+DL+LAH +DL RL++ EQGKPLAEAKGEV Y AS+++WF EEA R Sbjct: 62 ARTAKERGAILRRWSDLILAHADDLARLMTDEQGKPLAEAKGEVVYGASFIDWFAEEAKR 121 Query: 129 ANGDIIPAPVTGRRMMALKEPVGVVAAITPWNFPAAMIARKIAPALAAGCTVVCKPAEDT 188 A G IP P+ G+R+ ++K+PVGV AAI PWNFP AMI RK+ PALAAGCTVV KPA +T Sbjct: 122 AYGHTIPTPMPGKRLASIKQPVGVCAAIAPWNFPIAMITRKVGPALAAGCTVVVKPAAET 181 Query: 189 PLTSLAIIRLALEAGVPAGVINIVTASRERTPEVVDVWLADSRVRKISFTGSTAVGKHLA 248 PL++LAI RLA EAGVPAGV+NIVT + R+ EV V DSRVRK+SFTGST +GK L Sbjct: 182 PLSALAIARLATEAGVPAGVLNIVTTT--RSSEVGKVLCDDSRVRKLSFTGSTPIGKVLY 239 Query: 249 RHSADTLKKLSLELGGNAPFIVFDDADLDAAIDGVMAAKFRNGGQTCVSPNRIYVQEKVY 308 + A T+KKLSLELGGNAPFIVFDDADL+AA+DG +A+K+RN GQTCV NR+ VQ ++ Sbjct: 240 QQCAGTMKKLSLELGGNAPFIVFDDADLEAAVDGAIASKYRNAGQTCVCANRLIVQSGIH 299 Query: 309 DAFVAKLGARVAALKVGPATDPASQIGPMINARAIAKIDQHVRDAIERGARVITGGKRLQ 368 DAF A+L +VAALKVGP T QIGP+IN +A+ K+ V A++ GA V+TGG + Sbjct: 300 DAFAARLAEKVAALKVGPGTGEGVQIGPLINEKALTKVVGLVSGAVQAGAEVLTGGD-VH 358 Query: 369 GPGFDSDNYYAPTVLANVTGQMQCSCEETFGPVAPVTRFATEEEVVTAANATPFGLAAYF 428 G G ++Y PTVL T +M+ EE FGPVAP+ +F TE E V ANATPFGLAAYF Sbjct: 359 GLG---GHFYQPTVLVGATPEMRIFQEEIFGPVAPIVKFETEAEAVELANATPFGLAAYF 415 Query: 429 YSTDVRRIHRVTDALESGIVGVNEGALAAEAAPFGGVKESGYGREGSVHGLDDYLHTKYV 488 YS DV R RV + +E+G+VG+NEG ++ E APFGGVKESG GREG+ GLD+YL TKY+ Sbjct: 416 YSRDVGRCWRVAEQIEAGMVGINEGLISTEVAPFGGVKESGLGREGASEGLDEYLETKYL 475 Query: 489 CQG 491 C G Sbjct: 476 CFG 478 >gabD [C] COG1012 NAD-dependent aldehyde dehydrogenases Eco Escherichia coli K12 Length = 482 Score = 543 bits (1400), Expect = e-154, Method: Compositional matrix adjust. Identities = 260/488 (53%), Positives = 346/488 (70%), Gaps = 7/488 (1%) Query: 4 LELQRPDLMPGTQLIGAQWRAAADGRVLEVSNPATGQVFATVPDGNAEDARAAVDAAVAA 63 ++L +L LI +W A +G ++V+NPA G +VP A++ RAA+DAA A Sbjct: 1 MKLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRA 60 Query: 64 FPAWRATPAKQRATIIKRWNDLLLAHQEDLGRLISREQGKPLAEAKGEVAYAASYVEWFG 123 PAWRA AK+RATI++ W +L++ HQ+DL RL++ EQGKPLAEAKGE++YAAS++EWF Sbjct: 61 LPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 124 EEATRANGDIIPAPVTGRRMMALKEPVGVVAAITPWNFPAAMIARKIAPALAAGCTVVCK 183 EE R GD IP +R++ +K+P+GV AAITPWNFPAAMI RK PALAAGCT+V K Sbjct: 121 EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK 180 Query: 184 PAEDTPLTSLAIIRLALEAGVPAGVINIVTASRERTPEVVDVWLADSRVRKISFTGSTAV 243 PA TP ++LA+ LA+ AGVPAGV N+VT S V + ++ VRK+SFTGST + Sbjct: 181 PASQTPFSALALAELAIRAGVPAGVFNVVTGS---AGAVGNELTSNPLVRKLSFTGSTEI 237 Query: 244 GKHLARHSADTLKKLSLELGGNAPFIVFDDADLDAAIDGVMAAKFRNGGQTCVSPNRIYV 303 G+ L A +KK+SLELGGNAPFIVFDDADLD A++G +A+KFRN GQTCV NR+YV Sbjct: 238 GRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYV 297 Query: 304 QEKVYDAFVAKLGARVAALKVGPATDPASQIGPMINARAIAKIDQHVRDAIERGARVITG 363 Q+ VYD F KL V+ L +G D IGP+I+ +A+AK+++H+ DA+E+GARV+ G Sbjct: 298 QDGVYDRFAEKLQQAVSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCG 357 Query: 364 GKRLQGPGFDSDNYYAPTVLANVTGQMQCSCEETFGPVAPVTRFATEEEVVTAANATPFG 423 GK + G N++ PT+L +V + S EETFGP+AP+ RF E +V+ AN T FG Sbjct: 358 GKAHERGG----NFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFG 413 Query: 424 LAAYFYSTDVRRIHRVTDALESGIVGVNEGALAAEAAPFGGVKESGYGREGSVHGLDDYL 483 LAAYFY+ D+ R+ RV +ALE GIVG+N G ++ E APFGG+K SG GREGS +G++DYL Sbjct: 414 LAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYL 473 Query: 484 HTKYVCQG 491 KY+C G Sbjct: 474 EIKYMCIG 481 >ZgabD [C] COG1012 NAD-dependent aldehyde dehydrogenases EcZ Escherichia coli O157:H7 EDL933 Length = 482 Score = 542 bits (1396), Expect = e-154, Method: Compositional matrix adjust. Identities = 258/488 (52%), Positives = 345/488 (70%), Gaps = 7/488 (1%) Query: 4 LELQRPDLMPGTQLIGAQWRAAADGRVLEVSNPATGQVFATVPDGNAEDARAAVDAAVAA 63 ++L +L LI +W A +G V++V+NPA G +VP A++ RAA+DAA A Sbjct: 1 MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA 60 Query: 64 FPAWRATPAKQRATIIKRWNDLLLAHQEDLGRLISREQGKPLAEAKGEVAYAASYVEWFG 123 P WRA AK+RA I++ W +L++ HQ+DL RL++ EQGKPLAEAKGE++YAAS++EWF Sbjct: 61 LPVWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 124 EEATRANGDIIPAPVTGRRMMALKEPVGVVAAITPWNFPAAMIARKIAPALAAGCTVVCK 183 EE R GD IP +R++ +K+P+GV AAITPWNFPAAMI RK PALAAGCT+V K Sbjct: 121 EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK 180 Query: 184 PAEDTPLTSLAIIRLALEAGVPAGVINIVTASRERTPEVVDVWLADSRVRKISFTGSTAV 243 PA TP ++LA+ LA+ AG+PAGV N+VT S V + ++ VRK+SFTGST + Sbjct: 181 PASQTPFSALALAELAIRAGIPAGVFNVVTGS---AGAVGNELTSNPLVRKLSFTGSTEI 237 Query: 244 GKHLARHSADTLKKLSLELGGNAPFIVFDDADLDAAIDGVMAAKFRNGGQTCVSPNRIYV 303 G+ L A +KK+SLELGGNAPFIVFDDADLD A++G +A+KFRN GQTCV NR+YV Sbjct: 238 GRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYV 297 Query: 304 QEKVYDAFVAKLGARVAALKVGPATDPASQIGPMINARAIAKIDQHVRDAIERGARVITG 363 Q+ VYD F KL V+ L +G D IGP+I+ +A+AK+++H+ DA+E+GARV+ G Sbjct: 298 QDGVYDRFAEKLQQAVSKLHIGDGLDKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCG 357 Query: 364 GKRLQGPGFDSDNYYAPTVLANVTGQMQCSCEETFGPVAPVTRFATEEEVVTAANATPFG 423 GK + G N++ PT+L +V + S EETFGP+AP+ RF E +V+ AN T FG Sbjct: 358 GKAHERGG----NFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFG 413 Query: 424 LAAYFYSTDVRRIHRVTDALESGIVGVNEGALAAEAAPFGGVKESGYGREGSVHGLDDYL 483 LAAYFY+ D+ R+ RV +ALE GIVG+N G ++ E APFGG+K SG GREGS +G++DYL Sbjct: 414 LAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYL 473 Query: 484 HTKYVCQG 491 KY+C G Sbjct: 474 EIKYMCIG 481 >ECs3522 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ecs Escherichia coli O157:H7 Length = 482 Score = 542 bits (1396), Expect = e-154, Method: Compositional matrix adjust. Identities = 258/488 (52%), Positives = 345/488 (70%), Gaps = 7/488 (1%) Query: 4 LELQRPDLMPGTQLIGAQWRAAADGRVLEVSNPATGQVFATVPDGNAEDARAAVDAAVAA 63 ++L +L LI +W A +G V++V+NPA G +VP A++ RAA+DAA A Sbjct: 1 MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA 60 Query: 64 FPAWRATPAKQRATIIKRWNDLLLAHQEDLGRLISREQGKPLAEAKGEVAYAASYVEWFG 123 P WRA AK+RA I++ W +L++ HQ+DL RL++ EQGKPLAEAKGE++YAAS++EWF Sbjct: 61 LPVWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA 120 Query: 124 EEATRANGDIIPAPVTGRRMMALKEPVGVVAAITPWNFPAAMIARKIAPALAAGCTVVCK 183 EE R GD IP +R++ +K+P+GV AAITPWNFPAAMI RK PALAAGCT+V K Sbjct: 121 EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK 180 Query: 184 PAEDTPLTSLAIIRLALEAGVPAGVINIVTASRERTPEVVDVWLADSRVRKISFTGSTAV 243 PA TP ++LA+ LA+ AG+PAGV N+VT S V + ++ VRK+SFTGST + Sbjct: 181 PASQTPFSALALAELAIRAGIPAGVFNVVTGS---AGAVGNELTSNPLVRKLSFTGSTEI 237 Query: 244 GKHLARHSADTLKKLSLELGGNAPFIVFDDADLDAAIDGVMAAKFRNGGQTCVSPNRIYV 303 G+ L A +KK+SLELGGNAPFIVFDDADLD A++G +A+KFRN GQTCV NR+YV Sbjct: 238 GRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYV 297 Query: 304 QEKVYDAFVAKLGARVAALKVGPATDPASQIGPMINARAIAKIDQHVRDAIERGARVITG 363 Q+ VYD F KL V+ L +G D IGP+I+ +A+AK+++H+ DA+E+GARV+ G Sbjct: 298 QDGVYDRFAEKLQQAVSKLHIGDGLDKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCG 357 Query: 364 GKRLQGPGFDSDNYYAPTVLANVTGQMQCSCEETFGPVAPVTRFATEEEVVTAANATPFG 423 GK + G N++ PT+L +V + S EETFGP+AP+ RF E +V+ AN T FG Sbjct: 358 GKAHERGG----NFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFG 413 Query: 424 LAAYFYSTDVRRIHRVTDALESGIVGVNEGALAAEAAPFGGVKESGYGREGSVHGLDDYL 483 LAAYFY+ D+ R+ RV +ALE GIVG+N G ++ E APFGG+K SG GREGS +G++DYL Sbjct: 414 LAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYL 473 Query: 484 HTKYVCQG 491 KY+C G Sbjct: 474 EIKYMCIG 481