BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0918.p (447 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1093 [GEPR] COG0477 Permeases of the major facilitator superf... 307 3e-83 RSp0896 [GEPR] COG0477 Permeases of the major facilitator superf... 276 5e-74 PA0235 [GEPR] COG0477 Permeases of the major facilitator superfa... 275 2e-73 ECs3031 [GEPR] COG0477 Permeases of the major facilitator superf... 261 2e-69 Z3394 [GEPR] COG0477 Permeases of the major facilitator superfam... 261 2e-69 >RSc1093 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 454 Score = 307 bits (787), Expect = 3e-83, Method: Compositional matrix adjust. Identities = 180/442 (40%), Positives = 255/442 (57%), Gaps = 9/442 (2%) Query: 10 PTVHVDQVVEQGRFGAFQFSLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPV 69 P + V +++ RF AFQ+S++LLC + IDGFD +G++APA+ DW + A LG V Sbjct: 6 PVIDVRAWLDRQRFSAFQWSVVLLCFFVVAIDGFDTACVGFIAPALAQDWHIGPAVLGTV 65 Query: 70 FGAGLLGMLLGSLVLTPVGDRYGRRPVLIVSTLFFAVCMLVTPLVSSLDQLLVVRFITGF 129 F AGL G+++G+L+ P+ DR GR+ L+ + F + +++ S+ L+ +RF+TG Sbjct: 66 FSAGLAGLMVGALIFGPLADRIGRKQTLLFTVGAFGLASVLSAFAPSVGALVALRFLTGL 125 Query: 130 GLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPHHGWHSVFWVG 189 GLG MPNA+AL E+ P R ++ CGFT+G+ GG V+A L+P GW SV G Sbjct: 126 GLGGAMPNAIALTSEYCPERRRAFLTTVMFCGFTLGSGFGGIVAAQLVPEFGWRSVLLFG 185 Query: 190 GAVPLVLGLAMLVWLPESIQFLVLHRRPHAQVARWLRKLDPAIVIDDKSNIVVKEAK--A 247 G +PL+L M+ LPES+++LV A V R L ++ P V D ++ + A A Sbjct: 186 GVIPLLLLPVMVFALPESVRYLVAKGGQSAAVGRLLNRIAPVQVTPDTRFVLHETAAKGA 245 Query: 248 EGMPVAALFRDGRAGVTVLLWVISFMNLINLYFLSNWLPTLIHDAGYSTSTAVLIATSLQ 307 G PV LF T+LLW + FM+L+ +Y ++NWLPTLIH G + + A IA Q Sbjct: 246 PGSPVRQLFLPAFRTGTLLLWSVFFMSLLIVYLMTNWLPTLIHSGGVALALASRIAVMYQ 305 Query: 308 VGGVIGTLSLGRFIHRFGFTRVLGVCFLLACLSIALIGKVAAIPELLFVAVIVAGFCIVG 367 +GG +G L +GR + R+ T VL + L + L G +L +AV GFCI G Sbjct: 306 LGGTVGALVIGRMMDRYPATVVLCCTYGLGAGFLVLTGVSQG--TMLAIAVTGVGFCISG 363 Query: 368 GQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWSNGSLFVAAAIP 427 Q NA A FYPT R TGI WALGIGR+GSV G +IGG L+A LF+ A+P Sbjct: 364 SQIGANAFAAQFYPTASRVTGISWALGIGRLGSVCGALIGGVLLAANIGFQLLFLLVAVP 423 Query: 428 ALISALTI-----TRLHRRSQG 444 A I++L I H +QG Sbjct: 424 AAIASLAIFLCGAQARHVETQG 445 >RSp0896 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 458 Score = 276 bits (707), Expect = 5e-74, Method: Compositional matrix adjust. Identities = 170/430 (39%), Positives = 239/430 (55%), Gaps = 9/430 (2%) Query: 3 IHASGALPTVHVDQVVEQGRFGAFQFSLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVS 62 ++A A V V +V++ R A+Q +L LC ++DGFD A+GY+APA+ W ++ Sbjct: 1 MNALPARADVPVREVIDGSRLSAYQGLVLALCFAAAMLDGFDTAAIGYIAPALREAWHLT 60 Query: 63 KASLGPVFGAGLLGMLLGSLVLTPVGDRYGRRPVLIVSTLFFAVCMLVTPLVSSLDQLLV 122 L P FGAGL G++LGS+ L PV DR+GR+PVL++S L F V L SL+ L++ Sbjct: 61 PPQLAPAFGAGLFGLMLGSMGLGPVADRFGRKPVLLMSVLVFGVATLACAASDSLNTLVM 120 Query: 123 VRFITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPHHGW 182 +RF+TG GLG MP + L E+SP R+ + L GFT G A GG V+A ++P +GW Sbjct: 121 LRFLTGLGLGGAMPICITLSAEYSPQRHRMLLVTLSWSGFTSGLALGGLVAAEILPVYGW 180 Query: 183 HSVFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPHAQVARWLRKLDPAIVIDDKSNIVV 242 V GG PLVL + +W+PES+QFL +RP Q A LR++ I D + V Sbjct: 181 RGVLVAGGVTPLVLLPVLALWMPESVQFLA--QRP--QCADALRQIVTRIAGHDHGDGVT 236 Query: 243 ---KEAKAEGMPVAA--LFRDGRAGVTVLLWVISFMNLINLYFLSNWLPTLIHDAGYSTS 297 EG P LF DG A TVLLW F +L Y L++WLP ++ D G + + Sbjct: 237 FIGDRPAQEGAPFPGRNLFSDGMAQRTVLLWAAFFCSLFVFYLLTSWLPVVMRDQGLTLT 296 Query: 298 TAVLIATSLQVGGVIGTLSLGRFIHRFGFTRVLGVCFLLACLSIALIGKVAAIPELLFVA 357 A + + +GG IG ++L + R G R L + +++A IG L Sbjct: 297 EAARVGAMVPLGGTIGAIALALLMDRAGSPRALIAAYFCGAIAVAAIGLAIGNVAALTAV 356 Query: 358 VIVAGFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWSN 417 V V GF I G Q +N LA YPT R+TG+ WALG+GR GS+ G ++GG L+ S Sbjct: 357 VFVVGFGIAGAQNGINLLAAQMYPTEARATGVSWALGVGRGGSITGSLVGGTLMTTVGSV 416 Query: 418 GSLFVAAAIP 427 +LF A+P Sbjct: 417 QTLFGIIALP 426 >PA0235 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 448 Score = 275 bits (703), Expect = 2e-73, Method: Compositional matrix adjust. Identities = 167/415 (40%), Positives = 251/415 (60%), Gaps = 4/415 (0%) Query: 6 SGALPTVH---VDQVVEQGRFGAFQFSLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVS 62 S +LP V V + +Q+ ++LLC L + +DG D AMG++APA+ DWG+ Sbjct: 3 SPSLPAVERLDVQAFINAQPLSPYQWRIVLLCFLIVFLDGLDTAAMGFIAPALTQDWGID 62 Query: 63 KASLGPVFGAGLLGMLLGSLVLTPVGDRYGRRPVLIVSTLFFAVCMLVTPLVSSLDQLLV 122 +ASLGPV A L+GM+ G+L P+ DRYGR+ VL+ + F + L + ++++QLL Sbjct: 63 RASLGPVMSAALIGMVFGALGSGPLADRYGRKLVLVAAVFLFGLFSLASAYSTNVEQLLA 122 Query: 123 VRFITGFGLGSIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPHHGW 182 +RF+TG GLG+ MPNA L+ E++P + + + CGF +G A GGFVSA LIP GW Sbjct: 123 LRFLTGLGLGAAMPNATTLLSEYTPERLKSLLVTSMFCGFNLGMACGGFVSAKLIPLFGW 182 Query: 183 HSVFWVGGAVPLVLGLAMLVWLPESIQFLVLHRRPHAQVARWLRKLDPAIVIDDKSNIVV 242 HS+ +GG +PLVL + +L LPES ++LV+ R +V + L + PA V +S V Sbjct: 183 HSLLLLGGLLPLVLAVVLLFRLPESARYLVVRNRGSERVRQVLAPIAPAQVALARSFHVP 242 Query: 243 KEAKAEGMPV-AALFRDGRAGVTVLLWVISFMNLINLYFLSNWLPTLIHDAGYSTSTAVL 301 ++ + V A +F + T+LLW+ FM L+ +Y L++WLPTL+ D+G S A Sbjct: 243 EQQTVQARNVFAVIFSGTYSAGTLLLWLTYFMGLVIVYLLTSWLPTLMRDSGASLEQAAF 302 Query: 302 IATSLQVGGVIGTLSLGRFIHRFGFTRVLGVCFLLACLSIALIGKVAAIPELLFVAVIVA 361 I Q GGV+ +++G + RF +V+G+ +LLA + +G+ LL V++A Sbjct: 303 IGALFQFGGVLSAVAVGWAMDRFNPHKVIGLFYLLAGVFAWCVGQSLGQVTLLATLVLLA 362 Query: 362 GFCIVGGQPAVNALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWS 416 G CI G Q A+ +LA FYPT R+TG+ W LGIGR G+++G IG L+ L W+ Sbjct: 363 GMCINGAQSAMPSLAARFYPTQGRATGVSWMLGIGRFGAILGAWIGATLLGLGWN 417 >ECs3031 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 452 Score = 261 bits (668), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 152/426 (35%), Positives = 251/426 (58%), Gaps = 1/426 (0%) Query: 13 HVDQVVEQGRFGAFQFSLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W ++ L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGA 65 Query: 73 GLLGMLLGSLVLTPVGDRYGRRPVLIVSTLFFAVCMLVTPLVSSLDQLLVVRFITGFGLG 132 GLLG+ G+L+ P+ DR+GR+ V+ + F L + L L+ +RF+TG GLG Sbjct: 66 GLLGLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPHHGWHSVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPHAQVARWLRKLDPAIVIDDKSNIVVKEAKAEGMPV 252 PL+L +A+LV LPES ++ V + P A +A+ + + +D ++ + +G + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKG-SI 244 Query: 253 AALFRDGRAGVTVLLWVISFMNLINLYFLSNWLPTLIHDAGYSTSTAVLIATSLQVGGVI 312 LF + +T++LWV+ FM+L+ +Y LS+W+PTL++ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 313 GTLSLGRFIHRFGFTRVLGVCFLLACLSIALIGKVAAIPELLFVAVIVAGFCIVGGQPAV 372 G L+LG + +F RVL + + + + I +IG L+ +A+ G I G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 373 NALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWSNGSLFVAAAIPALISA 432 NAL T YPT R+TG+ W+ IGR G++VG + GG ++A+ +S +LF A+PA ISA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 433 LTITRL 438 + +T L Sbjct: 425 VMLTLL 430 >Z3394 [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 452 Score = 261 bits (667), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 151/426 (35%), Positives = 250/426 (58%), Gaps = 1/426 (0%) Query: 13 HVDQVVEQGRFGAFQFSLLLLCGLCLIIDGFDVQAMGYVAPAIIADWGVSKASLGPVFGA 72 + +++ G Q+ +++ C L +++DGFD A+G++AP I W ++ L P+FGA Sbjct: 6 DLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLSPLFGA 65 Query: 73 GLLGMLLGSLVLTPVGDRYGRRPVLIVSTLFFAVCMLVTPLVSSLDQLLVVRFITGFGLG 132 GLL + G+L+ P+ DR+GR+ V+ + F L + L L+ +RF+TG GLG Sbjct: 66 GLLXLTAGALLCGPLSDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLG 125 Query: 133 SIMPNAMALVGEFSPSSSRVTRMMLVSCGFTVGAAAGGFVSAALIPHHGWHSVFWVGGAV 192 MPN + + E+ P+ R + L+ CGFT+G+A GG VSA L+P GWH + +GG + Sbjct: 126 GAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVL 185 Query: 193 PLVLGLAMLVWLPESIQFLVLHRRPHAQVARWLRKLDPAIVIDDKSNIVVKEAKAEGMPV 252 PL+L +A+LV LPES ++ V + P A +A+ + + +D ++ + +G + Sbjct: 186 PLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVTKG-SI 244 Query: 253 AALFRDGRAGVTVLLWVISFMNLINLYFLSNWLPTLIHDAGYSTSTAVLIATSLQVGGVI 312 LF + +T++LWV+ FM+L+ +Y LS+W+PTL++ G A + + Q+GG + Sbjct: 245 RQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTL 304 Query: 313 GTLSLGRFIHRFGFTRVLGVCFLLACLSIALIGKVAAIPELLFVAVIVAGFCIVGGQPAV 372 G L+LG + +F RVL + + + + I +IG L+ +A+ G I G Q + Sbjct: 305 GALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGL 364 Query: 373 NALAGTFYPTTLRSTGIGWALGIGRIGSVVGPVIGGQLIALQWSNGSLFVAAAIPALISA 432 NAL T YPT R+TG+ W+ IGR G++VG + GG ++A+ +S +LF A+PA ISA Sbjct: 365 NALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISA 424 Query: 433 LTITRL 438 + +T L Sbjct: 425 VMLTLL 430