BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0861.p (241 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGl1073 [IQR] COG1028 Dehydrogenases with different specificitie... 377 e-104 SMc01991 [IQR] COG1028 Dehydrogenases with different specificiti... 300 1e-81 AGl3337 [IQR] COG1028 Dehydrogenases with different specificitie... 138 1e-32 mll4054 [IQR] COG1028 Dehydrogenases with different specificitie... 137 2e-32 YPO3351 [IQR] COG1028 Dehydrogenases with different specificitie... 134 2e-31 >AGl1073 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 270 Score = 377 bits (968), Expect = e-104, Method: Compositional matrix adjust. Identities = 192/241 (79%), Positives = 216/241 (89%) Query: 1 MQFGGTSVIITGAGKGIGRACARLMAQRGAEVIALSRTASDLESLREEIGGRSVQVDLAD 60 MQF G SVIITGAGKGIGRACA+LMA RGAEV+A+SRT SDL+SL+ EIGGRS++VDLAD Sbjct: 30 MQFSGKSVIITGAGKGIGRACAQLMAARGAEVVAISRTQSDLDSLKSEIGGRSIRVDLAD 89 Query: 61 PAAARRAMAEAGSADYLINSAGINVLQSTLAMSDDAYEAVLGVNLRAALITCQAFAQARI 120 AA R AMAEAG D+LINSAGINVL+S L MSD YEAVLG+NLRAAL+TCQ FA+ R+ Sbjct: 90 IAATRAAMAEAGPCDFLINSAGINVLESVLDMSDAGYEAVLGINLRAALVTCQEFARGRV 149 Query: 121 AAGGGGAIVNITSIAGHRGFAEHLCYAASKAGLEGATRVLARELGPHGIRVNAVAPTITL 180 A GGGGAIVNITSIAGHRGF +HLCYAASKAGLEGATRVLA+ELGPHGIRVNAVAPTITL Sbjct: 150 ANGGGGAIVNITSIAGHRGFQDHLCYAASKAGLEGATRVLAKELGPHGIRVNAVAPTITL 209 Query: 181 TELAEAAWSDPAKSAPMMVRHPLQRFASAEDVARSIAMLLSEDAAMMTGAVVPVDGGFLA 240 TELA AW+DP KS PMMVRHPL RFA AE+VA+SIA+LLS+D+ M++GAV+PVDGGFLA Sbjct: 210 TELAAEAWNDPEKSQPMMVRHPLNRFAEAEEVAQSIALLLSDDSKMISGAVLPVDGGFLA 269 Query: 241 V 241 V Sbjct: 270 V 270 >SMc01991 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 241 Score = 300 bits (769), Expect = 1e-81, Method: Compositional matrix adjust. Identities = 167/241 (69%), Positives = 197/241 (81%) Query: 1 MQFGGTSVIITGAGKGIGRACARLMAQRGAEVIALSRTASDLESLREEIGGRSVQVDLAD 60 M+F G SVI+TG GKGIGRA L+A RGA+V+ALSRT SDL+ L + G + DLAD Sbjct: 1 MEFSGKSVIVTGGGKGIGRATVALLAARGAQVVALSRTQSDLDELSSQTGCHGIVADLAD 60 Query: 61 PAAARRAMAEAGSADYLINSAGINVLQSTLAMSDDAYEAVLGVNLRAALITCQAFAQARI 120 AAAR AM EAG+ D L+N AG NVL+S + M+DD Y+ V+ NLRAALI Q FA+AR+ Sbjct: 61 AAAARAAMVEAGTCDILVNCAGTNVLESLIDMTDDGYDVVMNTNLRAALICAQEFARARM 120 Query: 121 AAGGGGAIVNITSIAGHRGFAEHLCYAASKAGLEGATRVLARELGPHGIRVNAVAPTITL 180 AAGGGGAIVN+TSIAGHRGF H+CYAASKAGLEGATRV+A+ELGP+GIRV A+APTIT+ Sbjct: 121 AAGGGGAIVNVTSIAGHRGFQNHVCYAASKAGLEGATRVMAKELGPYGIRVVAIAPTITM 180 Query: 181 TELAEAAWSDPAKSAPMMVRHPLQRFASAEDVARSIAMLLSEDAAMMTGAVVPVDGGFLA 240 TELA AAW+DP KS PMMVRHP RFA+ +DVARSIAMLLS DA M++GAV+PVDGGFLA Sbjct: 181 TELAAAAWADPQKSEPMMVRHPAGRFATVDDVARSIAMLLSSDAEMVSGAVLPVDGGFLA 240 Query: 241 V 241 V Sbjct: 241 V 241 >AGl3337 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 247 Score = 138 bits (347), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 90/239 (37%), Positives = 138/239 (57%), Gaps = 4/239 (1%) Query: 5 GTSVIITGAGKGIGRACARLMAQRGAEVIALSRTASD--LESLREEIGGRS-VQVDLADP 61 G ++TGA G+G+A A +A GAEV+ +R A D L+ + ++ G S + +D ADP Sbjct: 9 GRKALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALLIDFADP 68 Query: 62 AAARRAMAEAGSADYLINSAGINVLQSTLAMSDDAYEAVLGVNLRAALITCQAFAQARIA 121 AA+ + +AG D L+N+AGI ++ S+ ++ V+ VNL+A T QAFA+ +A Sbjct: 69 LAAKDSFTDAGF-DILVNNAGIIRRADSVEFSELDWDEVMDVNLKALFFTTQAFAKELLA 127 Query: 122 AGGGGAIVNITSIAGHRGFAEHLCYAASKAGLEGATRVLARELGPHGIRVNAVAPTITLT 181 G G +VNI S+ +G Y A+K G+ G T++LA E GI VNA+AP T Sbjct: 128 KGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYIET 187 Query: 182 ELAEAAWSDPAKSAPMMVRHPLQRFASAEDVARSIAMLLSEDAAMMTGAVVPVDGGFLA 240 EA +D A++ ++ R P R+ +ED+A + L S A + GA++ VDGG+LA Sbjct: 188 NNTEALRADAARNKAILERIPAGRWGHSEDIAGAAVFLSSAAADYVHGAILNVDGGWLA 246 >mll4054 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 258 Score = 137 bits (346), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 90/247 (36%), Positives = 133/247 (53%), Gaps = 7/247 (2%) Query: 1 MQFGGTSVIITGAGKGIGRACARLMAQRGAEVIALSRTASDLESLR-EEIGGR--SVQVD 57 G +++TGA GIG+ +A+ G VI + R++ D + + IG R +V D Sbjct: 11 FSLAGKRILVTGANTGIGQGIVLSIARAGGVVIGVGRSSMDETASKVAAIGARFETVSAD 70 Query: 58 LADPAAA----RRAMAEAGSADYLINSAGINVLQSTLAMSDDAYEAVLGVNLRAALITCQ 113 LAD A A R E+G D L+N+AGI + +++ ++ V+ VNL+ + CQ Sbjct: 71 LADTATAGPMLDRVWDESGPLDGLVNNAGIIRRADAVDLTETDWDDVMDVNLKTVFLLCQ 130 Query: 114 AFAQARIAAGGGGAIVNITSIAGHRGFAEHLCYAASKAGLEGATRVLARELGPHGIRVNA 173 +FA+ +A G G IVNI S+ +G Y ASK G+ G TR+LA E GI VNA Sbjct: 131 SFARRALADGRRGKIVNIASVLSFQGGIRVASYTASKHGVLGITRLLACEWAAKGINVNA 190 Query: 174 VAPTITLTELAEAAWSDPAKSAPMMVRHPLQRFASAEDVARSIAMLLSEDAAMMTGAVVP 233 +AP T +A +DP +SA ++ R P R+ D+ + LL+ + M GA VP Sbjct: 191 IAPGYVETNNTQALRADPDRSAAILGRIPAGRWGEPSDIGDAAVFLLARASDYMHGAAVP 250 Query: 234 VDGGFLA 240 VDGG+LA Sbjct: 251 VDGGWLA 257 >YPO3351 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ype Yersinia pestis Length = 256 Score = 134 bits (337), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 86/236 (36%), Positives = 129/236 (54%), Gaps = 10/236 (4%) Query: 10 ITGAGKGIGRACARLMAQRGAEVIALSRTASDLESLREEIGGRS---VQVDLADPAAARR 66 ITG GIG A A L +GA V+ L A ++ + E++ + + D++D + R+ Sbjct: 21 ITGGATGIGHAIAELYLAKGARVV-LMDCADNVAEIAEQLDRDNAVGLHCDVSDSQSVRQ 79 Query: 67 AMAEA----GSADYLINSAGINVLQSTLAMSDDAYEAVLGVNLRAALITCQAFAQARIAA 122 A+A+A G D L+NSAGI L + + ++ + +NL+ + CQ + I Sbjct: 80 AVAQAIGAFGQLDILVNSAGIAALDPAEKVREQDWDRTIDINLKGVFLMCQEVGKHFIQH 139 Query: 123 GGGGAIVNITSIAGHRGFAEHLCYAASKAGLEGATRVLARELGPHGIRVNAVAPTITLTE 182 G G IVN+ S AG HL Y ASK G+ G T+VLA E GP I+VNA++PT+ LT Sbjct: 140 GHG-KIVNLASQAGVVALPNHLAYCASKFGVIGITKVLALEWGPLDIQVNAISPTVVLTA 198 Query: 183 LAEAAWSDPAKSAPMMVRHPLQRFASAEDVARSIAMLLSEDAAMMTGAVVPVDGGF 238 L + AWS + M ++ P +RFA +VA L S+ A M+TG + +DGG+ Sbjct: 199 LGQKAWSGQL-AEDMKLKIPARRFAYPAEVAACALFLASDAANMITGENLVIDGGY 253