BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0846.p (289 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc5105 [R] COG3618 Predicted metal-dependent hydrolase of the T... 155 8e-38 mll5767 Non COG 83 8e-16 mlr1708 Non COG 78 2e-14 BMEI1718 [R] COG3618 Predicted metal-dependent hydrolase of the ... 73 9e-13 mlr7156 Non COG 69 8e-12 >AGc5105 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 287 Score = 155 bits (393), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 99/285 (34%), Positives = 147/285 (51%), Gaps = 17/285 (5%) Query: 6 LDAHQHFWRYRAEDYPWIGQGMELLACDRLPGQLHPLLAAEGLHASIAVQARAGREETGF 65 +DAHQHFW + W + + D LP L PLL A G+ ++ VQ +T F Sbjct: 17 IDAHQHFWLMKDRAGQWPPPSLAAIYRDFLPTDLSPLLTAAGVSGTVLVQTMETAADTDF 76 Query: 66 LLDLARGDRRIAGVVGWEDLSSPHLAANVAQWGRDKLL-GFRHQVQDEADVTAFIEAPAF 124 +L+LA I GVVGW D+ S + A +A+ + G R +Q DV A+I+ A Sbjct: 77 MLELAENTDFIKGVVGWVDMKSAEVTAEIARRAKHPAFKGVRPMLQGMEDV-AWIDDAAL 135 Query: 125 NAGIKWLQQQGLVYDVLIYARQMPEVQAFCARHDRHWLVLDHLGKPALAEFGRGEVVFDA 184 NA ++ L + GLV+D L+ +P + +F ++H +V+DH KP +A + Sbjct: 136 NAAVEALVKHGLVFDALVLPPNLPHLLSFASKHPELPVVIDHGAKPLIATGH-----YRD 190 Query: 185 WKRQLRALAAMPHVACKLSGLVTEADWLRGLRKKDYDNIVLCLDTALEAFGPERLMFGSD 244 W+R + ALAA P+V CKLSGL+TE R + Y +T LE FG +R++FGSD Sbjct: 191 WRRNMAALAARPNVHCKLSGLLTERGEQRPEAVRPY------AETILELFGGDRVIFGSD 244 Query: 245 WPVCLLAASYATVAGVVREWAATRLSEQEQEQVWGATAARCYALA 289 WPV LA + R+ + ++ V+G A R Y+L Sbjct: 245 WPVLRLAGDFQGWLDFCRDI----VPAKDHAAVFGGNAIRFYSLT 285 >mll5767 Non COG Length = 297 Score = 82.8 bits (203), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 79/305 (25%), Positives = 127/305 (41%), Gaps = 36/305 (11%) Query: 6 LDAHQHFWRYRAEDYPWIGQGMELLACD-----RLPGQLHPLLA-------AEGLHASIA 53 +D H H W YPW+ G++ A R +L L + +H + Sbjct: 7 IDPHHHLWDLEVNYYPWLTDGVKPSAFGDYEAIRTNYRLDDYLEDARNQNLVKSVHLDVG 66 Query: 54 VQARAGREETGFLLDLARGDRRIAGVVGWEDLSSPHLAANVAQ-WGRDKLLGFRHQVQDE 112 ET +L ++A G+VG+ DLS P + + + G R + Sbjct: 67 FDPSDPVGETRWLQEIANKRGFPHGIVGYADLSKPDVGELLDRHMEYPNFRGIRQSMNYH 126 Query: 113 ADVTAFIEA-------PAFNAGIKWLQQQGLVYDVLIYARQMPEVQAFCARHDRHWLVLD 165 AD +A P + G + L ++ L +D+ +Y QM E ++L+ Sbjct: 127 ADPAKTYQARPEVSRTPEWRRGFRELAKRRLSFDLQLYYPQMEEFLQLAHDFPDVQIILN 186 Query: 166 HLGKPALAEFGRGEVVFDAWKRQLRALAAMPHVACKLSGL-VTEADWLRGLRKKDYDNIV 224 H G G F+AWK+ + LA P+VACK+SGL + + W +I Sbjct: 187 HTGMQV-----DGPKHFNAWKKGMHRLAQAPNVACKISGLGMGDWSWTTA-------SIR 234 Query: 225 LCLDTALEAFGPERLMFGSDWPVCLLAASYATVAGVVREWAATRLSEQEQE-QVWGATAA 283 ++ A+ AFG R MF +++PV L +S+ V +E TR E+ ++ AA Sbjct: 235 PYVEEAIAAFGVGRSMFATNFPVDKLFSSFDAVVNAFKE--ITRYYPHEERLALFHDNAA 292 Query: 284 RCYAL 288 R Y L Sbjct: 293 RHYRL 297 >mlr1708 Non COG Length = 295 Score = 77.8 bits (190), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 78/301 (25%), Positives = 125/301 (41%), Gaps = 33/301 (10%) Query: 6 LDAHQHFWRYRAEDYPWIGQGM--------ELLACDRLPGQLHPLLAAEGLHASIAVQAR 57 +DAH H WR + D PW+ M E + D G+ G+ ++ VQ Sbjct: 5 IDAHFHIWRQK--DQPWLVGPMVPRIFGPYEPIRRDYPIGEFLQDQKGSGVEKAVYVQTN 62 Query: 58 AGRE----ETGFLLDLARGDRRIAGVVGWEDLSSPHLAANVAQWGRDKLL-GFRHQVQ-D 111 +E E FL A +VG+ D++ + + + + +LL G R Q+ Sbjct: 63 WAKEDFEKEVAFLQQTADETGWPHAIVGYADMTVDDVRPQIDRLMKYRLLRGVRMQLHWH 122 Query: 112 EADVTAF------IEAPAFNAGIKWLQQQGLVYDVLIYARQMPEVQAFCARHDRHWLVLD 165 E F + P A + L+ GL +D+ ++ QM + + +L Sbjct: 123 ETPAFRFAASADQVIDPKVRANVARLKDYGLSFDLQLFPAQMKDGVTLVGENPETNFILT 182 Query: 166 HLGKPALAEFGRGEVVFDAWKRQLRALAAMPHVACKLSGLVTEADWLRGLRKKDYDNIVL 225 H G G V + WK LR L+A P+ KLSGL T + + D I Sbjct: 183 HAGMLT----GMEPEVTETWKAGLRTLSAAPNFYAKLSGLGT------FVHRNDPALIAY 232 Query: 226 CLDTALEAFGPERLMFGSDWPVCLLAASYATVAGVVREWAATRLSEQEQEQVWGATAARC 285 +D A++ G + LMFGS++P+ L S+A + R+ A + E + W TA + Sbjct: 233 IVDNAIDILGADHLMFGSNFPIEKLWTSHAELIKAHRDAVARHGAAAEADIFWN-TAEKV 291 Query: 286 Y 286 Y Sbjct: 292 Y 292 >BMEI1718 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel fold Bme Brucella melitensis Length = 282 Score = 72.8 bits (177), Expect = 9e-13, Method: Compositional matrix adjust. Identities = 67/256 (26%), Positives = 103/256 (40%), Gaps = 22/256 (8%) Query: 6 LDAHQHFWRYRAEDYPWIGQGMEL---LACDRLPGQLHPLLAAEGLHASIAVQARAGREE 62 +D H H A YPW+ L D Q LH + V A + E Sbjct: 3 IDTHLHLIDKNALSYPWLESAPALNRDFLFDSYRLQAERAGIGGALHIEVDVAPHAMQAE 62 Query: 63 TGFLLDLAR-GDRRIAGVVGWEDLSSPHLAANVAQWGRDKLL-GFR---HQVQDEADVTA 117 T + +AR I G + P AA + + D + G R H V DE Sbjct: 63 TDHIRQIARRSGGFIKGAIASCRPEEPGFAAYLERQLSDPFVKGLRRVLHVVPDEVS--- 119 Query: 118 FIEAPAFNAGIKWLQQQGLVYDVLIYARQMPEVQAFCARHDRHWLVLDHLGKPALAEFGR 177 E F IK L+ GL +D+ + Q+ + A ++DH G P + Sbjct: 120 --EGALFRENIKRLEGTGLTFDLCVQPHQIGKAIALADLAPDLCFIVDHCGAPDIKAGA- 176 Query: 178 GEVVFDAWKRQLRALAAMPHVACKLSGLVTEADWLRGLRKKDYDNIVLCLDTALEAFGPE 237 D W+ + ++ P+V K+SGLV D + + + +++FG + Sbjct: 177 ----LDGWREGMAEISRRPNVIAKISGLVVYCD----AESWTVETLRPYAEQVIQSFGWD 228 Query: 238 RLMFGSDWPVCLLAAS 253 R+++GSDWPVC LA+S Sbjct: 229 RVIWGSDWPVCTLASS 244 >mlr7156 Non COG Length = 297 Score = 69.3 bits (168), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 69/265 (26%), Positives = 107/265 (40%), Gaps = 28/265 (10%) Query: 3 PLRLDAHQHFWRYRAEDYPWIGQGMEL---LACDRLPGQLHPLLAAEGLHASIAVQARAG 59 P+ +D H H A YPW+ +L + + + + LH + V Sbjct: 18 PVIIDTHLHLIDRSALRYPWLAGVPQLNRDFSYEDYATEAQRVGVERVLHMEVDVDPADI 77 Query: 60 REETGFLLDLAR--GDRRIAGVVGWEDLSSPHLAANVAQWGRDKLLGFR---HQVQDEAD 114 ET + L+R G + + + A Q + GFR H V D+ Sbjct: 78 EVETARVEGLSRQAGSMLVGAIASCRPEDADFPAYLERQRTNPFVKGFRRVLHVVPDD-- 135 Query: 115 VTAFIEAPAFNAGIKWLQQQGLVYDVLIYARQMPEVQAFCARHDRHWLVLDHLGKPALAE 174 E F IK L GL +D+++ Q+P+ A VLDH G P + Sbjct: 136 ---LSEGAVFRDNIKRLGGIGLTFDLVVLPHQIPKAIALADLAPDVQFVLDHCGVPDIK- 191 Query: 175 FGRGEVVFDAWKRQLRALAAMPHVACKLSGLVTEAD---WLRGLRKKDYDNIVLCLDTAL 231 G E W+ + +A P+V K+SG+V AD W G + ++ + Sbjct: 192 -GGAE---HPWRAHMSEIARRPNVMAKISGVVAYADPVNWTVGTLRP-------YVEHTI 240 Query: 232 EAFGPERLMFGSDWPVCLLAASYAT 256 AFG +R+++GSDWPVC L +T Sbjct: 241 AAFGWDRIVWGSDWPVCTLGGGLST 265