BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0834.p (261 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll7191 [IQR] COG1028 Dehydrogenases with different specificitie... 299 4e-81 CC0821 [IQR] COG1028 Dehydrogenases with different specificities... 244 1e-64 SMc00880 [IQR] COG1028 Dehydrogenases with different specificiti... 243 4e-64 mlr4741 [IQR] COG1028 Dehydrogenases with different specificitie... 238 8e-63 AGc1273 [IQR] COG1028 Dehydrogenases with different specificitie... 210 2e-54 >mll7191 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 258 Score = 299 bits (765), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 142/255 (55%), Positives = 178/255 (69%) Query: 7 DVQLASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAG 66 ++ A +PSLKG+ VFITGGG+GIG ++V F QG+ VAFVD++ E S L +AA G Sbjct: 4 EIGYAIYPSLKGRSVFITGGGSGIGESLVRHFCAQGSRVAFVDLSEEPSRHLVEAIAAEG 63 Query: 67 HPKPLFRHCDLRDIPAFQATIAELQGQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAI 126 HP PLF CDLRD+ QA A+ G VL NNA ND RH+ ++VT+ YW+DR+A+ Sbjct: 64 HPAPLFIPCDLRDVEQLQAATAQAMQHNGPIQVLCNNAGNDDRHQTKDVTVAYWDDRMAV 123 Query: 127 NQRPSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDL 186 N R FFA Q+V M +GGGSIINF SI+W P Y TAKA+ G+TR LAR+L Sbjct: 124 NLRHQFFAAQAVRPQMSAQGGGSIINFGSITWMVGDPDCPAYVTAKAAVYGMTRALAREL 183 Query: 187 GPHKIRVNTVTPGWVMTERQIKLWLDEEGKKSIARNQCLQGDLLPWHLARMVLFLAADDS 246 GP +IRVN + PGWVMTERQ++LWL+ G++ IA QCL L P +ARM LFLAADDS Sbjct: 184 GPERIRVNCMVPGWVMTERQMRLWLNPAGERQIAERQCLPDRLQPADIARMALFLAADDS 243 Query: 247 AMCTAQEFIVDAGWV 261 MCT+Q+FIVDAGWV Sbjct: 244 RMCTSQQFIVDAGWV 258 >CC0821 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ccr Caulobacter vibrioides Length = 248 Score = 244 bits (624), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 133/250 (53%), Positives = 172/250 (68%), Gaps = 6/250 (2%) Query: 11 ASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPKP 70 A +PSLKGKRV ITGGG+GIGA + FA+QGA V F+DIA E S AL E+A + P P Sbjct: 4 AIYPSLKGKRVVITGGGSGIGAGLTAGFARQGAEVIFLDIADEDSRALEAELAGSPIP-P 62 Query: 71 LFRHCDLRDIPAFQATIAELQGQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQRP 130 +++ CDL ++ A +A AE+ GD DVLVNNA ND RHKL +VT YW++RI +N R Sbjct: 63 VYKRCDLMNLEAIKAVFAEI----GDVDVLVNNAGNDDRHKLADVTGAYWDERINVNLRH 118 Query: 131 SFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPHK 190 F Q+V GMK+RGGG++INF SISWH +Y TAKA G+TR LAR+LGP Sbjct: 119 MLFCTQAVAPGMKKRGGGAVINFGSISWHLGLEDLVLYETAKAGIEGMTRALARELGPDD 178 Query: 191 IRVNTVTPGWVMTERQIKLWLDEEGKKSIARNQCLQGDLLPWHLARMVLFLAADDSAMCT 250 IRV V PG V T+RQ K W EG+ I QCL+G ++P ++A +VLFLA+DD+++CT Sbjct: 179 IRVTCVVPGNVKTKRQEK-WYTPEGEAQIVAAQCLKGRIVPENVAALVLFLASDDASLCT 237 Query: 251 AQEFIVDAGW 260 E+ +DAGW Sbjct: 238 GHEYWIDAGW 247 >SMc00880 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Sme Sinorhizobium meliloti Length = 256 Score = 243 bits (619), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 126/249 (50%), Positives = 163/249 (65%) Query: 11 ASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPKP 70 + FP L+ + V +TGGG+GIGAA+VEAFA+QGA VAFVDIA E+S ALC +VAA P Sbjct: 6 SQFPDLRDRGVLVTGGGSGIGAALVEAFARQGARVAFVDIAAESSLALCEKVAAQTGQAP 65 Query: 71 LFRHCDLRDIPAFQATIAELQGQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQRP 130 F DLR++ A +A E +LG VLVNNAA D R LE VT E W++ +++N R Sbjct: 66 HFIQADLRNVEAVRAAADEAVAKLGSVRVLVNNAARDDRQALEAVTEESWDESLSVNLRH 125 Query: 131 SFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPHK 190 FF Q+V M+R+GGGSI+NFSSI++ + P Y+TAKA +GLT+ LA LGP Sbjct: 126 LFFMCQAVAPHMQRQGGGSIVNFSSIAFLLNMPEIPAYSTAKAGIIGLTKSLAGKLGPDN 185 Query: 191 IRVNTVTPGWVMTERQIKLWLDEEGKKSIARNQCLQGDLLPWHLARMVLFLAADDSAMCT 250 IRVN + PG ++TERQ +LWL EE + QCL+ L+ L LFLA+D SA T Sbjct: 186 IRVNAILPGMIVTERQRRLWLTEESIARMQERQCLKRMLVADDLVGPCLFLASDSSAAMT 245 Query: 251 AQEFIVDAG 259 AQ I+D G Sbjct: 246 AQAMIIDGG 254 >mlr4741 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Mlo Mesorhizobium loti Length = 254 Score = 238 bits (608), Expect = 8e-63, Method: Compositional matrix adjust. Identities = 127/251 (50%), Positives = 163/251 (64%) Query: 11 ASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAAAGHPKP 70 A F LKG V ITGGG+GIGAA+ E F +QGA+VAF+DIA S L + + +P Sbjct: 4 ADFADLKGASVLITGGGSGIGAALTEGFVRQGANVAFIDIAEGPSTLLADRIEKEFGRRP 63 Query: 71 LFRHCDLRDIPAFQATIAELQGQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQRP 130 L+ DLRDI A +A+ A GD VL+NNAA D+RH +E+VT+E+W++ AIN RP Sbjct: 64 LYLKTDLRDIEALRASAARAAEAHGDVTVLINNAAWDERHAVEDVTVEFWDNNQAINLRP 123 Query: 131 SFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPHK 190 FF Q+V GMKR GGGSIINF+S S+ + P YT AKA LGLT+GLA LGP + Sbjct: 124 HFFTAQAVAPGMKRAGGGSIINFTSTSYLINHPDMPAYTAAKAGILGLTKGLAGKLGPDR 183 Query: 191 IRVNTVTPGWVMTERQIKLWLDEEGKKSIARNQCLQGDLLPWHLARMVLFLAADDSAMCT 250 IRVN V PGWV+TERQ + W+ E + QC++ + P + VLFLA+D S M T Sbjct: 184 IRVNAVAPGWVITERQQERWVTEGALAAHVAKQCIKEVMRPDDMVGTVLFLASDASRMLT 243 Query: 251 AQEFIVDAGWV 261 AQ IVD G++ Sbjct: 244 AQMLIVDGGFL 254 >AGc1273 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 260 Score = 210 bits (535), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 118/252 (46%), Positives = 155/252 (61%), Gaps = 2/252 (0%) Query: 11 ASFPSLKGKRVFITGGGTGIGAAIVEAFAQQGAHVAFVDIATEASEALCNEVAA-AGHPK 69 A FP LK V +TGGG+GIGA++VEAFA QGA V+F+DIA + S AL +AA HP Sbjct: 10 AQFPDLKDAGVLVTGGGSGIGASLVEAFAMQGAKVSFIDIAEQPSIALVERLAATVPHPV 69 Query: 70 PLFRHCDLRDIPAFQATIAELQGQLGDFDVLVNNAANDQRHKLEEVTLEYWNDRIAINQR 129 FR DL DI A + T+ G VLVNNAA D RH ++ VT YW+ A+N + Sbjct: 70 HYFR-ADLSDIDAIKRTVDMAASATGGIKVLVNNAAWDDRHDIDSVTEAYWDANQAVNLK 128 Query: 130 PSFFAVQSVVEGMKRRGGGSIINFSSISWHQSGGGFPVYTTAKASTLGLTRGLARDLGPH 189 FF VQ+ + +++ SI+NFSSIS+ + G P Y AKA +GLT+ LA LGP Sbjct: 129 QMFFTVQAALPHLRQAKDASIVNFSSISFLLNMGELPSYAAAKAGIIGLTKSLAGRLGPE 188 Query: 190 KIRVNTVTPGWVMTERQIKLWLDEEGKKSIARNQCLQGDLLPWHLARMVLFLAADDSAMC 249 IRVNT+ PG ++TERQ +LWL +EG + QCL+ L+ L+ LFLA+ S+ Sbjct: 189 NIRVNTLLPGMIVTERQKELWLTDEGITATTARQCLKRTLVAADLSGPCLFLASSASSAI 248 Query: 250 TAQEFIVDAGWV 261 TAQ IVD G + Sbjct: 249 TAQSIIVDGGLL 260