BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0821.p (390 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0585 [GEPR] COG0477 Permeases of the major facilitator superf... 291 1e-78 DR2502 [GEPR] COG0477 Permeases of the major facilitator superfa... 177 3e-44 mlr3825 [GEPR] COG0477 Permeases of the major facilitator superf... 174 4e-43 SMc03889 [GEPR] COG0477 Permeases of the major facilitator super... 162 1e-39 BMEI0267 [GEPR] COG0477 Permeases of the major facilitator super... 162 1e-39 >RSc0585 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 408 Score = 291 bits (746), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 195/374 (52%), Positives = 245/374 (65%), Gaps = 8/374 (2%) Query: 18 NATRATMAQFFVNGATFATWGVLIPSVKERFDLSDAVLSLAMLAVAGGALLTMGQSGKWI 77 +A ATMA FFVNGAT ATWGV IP+VK RF LS+A LSLAM VA GA+ M +G W Sbjct: 36 SARAATMALFFVNGATIATWGVHIPTVKARFGLSEASLSLAMFMVAAGAIAAMKFAGGWA 95 Query: 78 ARVGSARALRQVGILYAATLLLIPLAPQFWMLVALLLVFGSAMAAFDVAMSVQAALVEGR 137 ARV + RA Q G+++ L+ L P + +L+ LL++FG A A FDVA++ QA VE Sbjct: 96 ARVSTRRASVQAGVVFGLMTGLLMLMPSYALLLGLLVLFGIANAGFDVAINAQATTVEAH 155 Query: 138 RTRPIMSTLHAMFSIGGIAGSALGAVP---GLSPLAHAALVAAMTLAVALSIGPFALPDD 194 +PI+S+LH MFS+GG+ G+A G V G+ H A + +T +AL GPF LPD Sbjct: 156 SHKPIISSLHGMFSLGGMVGAAAGGVLLDLGVPAAVHCAGMGLITAGMALCAGPFMLPDH 215 Query: 195 THDDTSATPEGDH-SARRMVLVLGVIAFLALMCEGGMYDWAAVYMRDIAQSPVAWVSYSY 253 H A E H + R +LVLG++AFL L+ EG MYDW VYMR++AQSP A S Y Sbjct: 216 VH----APGEPAHPTTGRTLLVLGLLAFLGLVGEGAMYDWTTVYMREVAQSPEAQASAGY 271 Query: 254 AAFSTGMALGRLTGDRIRERIGGLRTLAWSGVAGATGIALAAAWPSPLATMAGLLLAGLG 313 AAFS GMAL R GD R R G R L SGV GI LA WP P A +AG L G+G Sbjct: 272 AAFSGGMALARFGGDAARARWGNTRVLGVSGVLATGGILLALLWPDPAAVLAGFALMGVG 331 Query: 314 IANLMPIFFLAAARVPGMAAAQSIAAVARFAYVGMLLGPVCIGGVAEHLGLRVSFVGVSL 373 AN++PIFF+ A+R+PG+ AA+ IAAVARFAYVGML+GPV IG +A H LR V+L Sbjct: 332 AANMVPIFFVTASRMPGVPAAEGIAAVARFAYVGMLIGPVFIGMIAHHSNLRWGLSLVAL 391 Query: 374 VMMMVALFGPRAVR 387 MM++A+ GPRA+R Sbjct: 392 TMMLIAVAGPRAIR 405 >DR2502 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 471 Score = 177 bits (450), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 146/371 (39%), Positives = 193/371 (52%), Gaps = 14/371 (3%) Query: 1 MHSDSSSVPASEAHRIRNATRATMAQFFVNGATFATWGVLIPSVKERFDLSDAVLSLAML 60 M + ++ VP S A A A A F +NGA FATW V IP V+ L++A + A+L Sbjct: 76 MTTTAAPVPRSPA--AERARLAVSAVFLINGALFATWAVNIPGVRTALHLTEAQVGAALL 133 Query: 61 AVAGGALLTMGQSGKWIARVGSARALRQVGILYAATLLLIPLAPQFWMLVALLLVFGSAM 120 AV G+LL+M +G W+AR GS R + L +LL P W L A L + G Sbjct: 134 AVGLGSLLSMPLTGGWVARWGSGRVTALLAPLTMLSLLPPFFMPSLWWLTAALGLLGVLN 193 Query: 121 AAFDVAMSVQAALVEGRRTRPIMSTLHAMFSIGGIAGSALG-AVPGLSP-LAHAALVAAM 178 A DVAM+ Q VE RP+MS LHA FS+GG+ G+ LG A+ G P LAH VA + Sbjct: 194 GALDVAMNAQGVTVEKALGRPVMSRLHAYFSLGGVVGALLGTALVGRVPMLAHVGGVALL 253 Query: 179 TLAVALSIGPFALPDDTHDDTSATPEGDHSARRMVL-----VLGVIAFLALMCEGGMYDW 233 + AL G F L D + +A + D R L +LG + FL ++ EG YDW Sbjct: 254 STLTALVAGRFLLADAPTEPETA--QADAPTPRSGLSPAALLLGGLCFLGMLSEGAHYDW 311 Query: 234 AAVYMRDIAQSPVAWVSYSYAAFSTGMALGRLTGDRIRERIGGLRTLAWSGVAGATGIAL 293 AA+Y RD+ P YAAF T M LGR GDR R R G + + + A G+ L Sbjct: 312 AALYCRDVLGLPGGQAGVGYAAFVTTMTLGRWFGDRARARFGDVAMVRAGALLSALGLGL 371 Query: 294 AAAWPSPLATMAGLLLAGLGIANLMPIFFLAAARVPGMAAAQSIAAVARFAYVGMLLGPV 353 A P G L+GLG++N++P+ + AA + IA VA Y G LLGP Sbjct: 372 ALLVREPWPATLGFALSGLGLSNVVPVMYGAAGHA---LHGRGIAQVATIGYGGFLLGPP 428 Query: 354 CIGGVAEHLGL 364 IG +A+H GL Sbjct: 429 LIGFLAQHSGL 439 >mlr3825 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 391 Score = 174 bits (440), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 132/383 (34%), Positives = 197/383 (51%), Gaps = 14/383 (3%) Query: 14 HRIRNATR---ATMAQFFVNGATFATWGVLIPSVKERFDLSDAVLSLAMLAVAGGALLTM 70 H ++ A R A A F NG +W IP R D+S L L +L GA+ M Sbjct: 5 HAMQTAIRGRWAVAAIFLANGFLTGSWAPQIPVFLTRLDISKFTLGLLILLFGAGAVTAM 64 Query: 71 GQSGKWIARVGSARALRQVGILYAATLLLIPLAPQFWMLVALLLVFGSAMAAFDVAMSVQ 130 G I++ GS LR G+ + LL++ LAP + + +FG ++ DVAM+ Sbjct: 65 TWCGHLISKHGSRTVLRWFGLCGSLGLLVVALAPNLPLAAIAMFIFGGSIGGMDVAMNAN 124 Query: 131 AALVEGRRTRPIMSTLHAMFSIGGIAGSALGA--VPGLSPLAHAALVAAMTLA-VALSIG 187 A +VE + +R IMS+ H +S+GG AG LG + LAHAA+V + A +A+++G Sbjct: 125 AVVVERKMSRAIMSSSHGFWSLGGFAGGGLGGFAIQHYGHLAHAAVVTVLAFAAIAMAVG 184 Query: 188 PFALPDD---THDDTSATPEGDHSARRMVLVLGVIAFLALMCEGGMYDWAAVYMRDIAQS 244 D A P A +V ++G++A L ++ EG + DWAA+Y+R + Sbjct: 185 YLVAEDKPQAAEHHKFALP-----ANPLVYLIGLMALLTMVSEGAVLDWAALYLRQELGA 239 Query: 245 PVAWVSYSYAAFSTGMALGRLTGDRIRERIGGLRTLAWSGVAGATGIALAAAWPSPLATM 304 +A +YAAFS MA+ R GD +R R G + TL S V ATG+ +A PSP + Sbjct: 240 DLAIAGLAYAAFSGVMAIMRFFGDGVRNRFGAVTTLRGSAVVAATGMLVAGLSPSPWFAI 299 Query: 305 AGLLLAGLGIANLMPIFFLAAARVPGMAAAQSIAAVARFAYVGMLLGPVCIGGVAEHLGL 364 A G GIAN++PI F A GM++ ++ V Y G+L+ P IG VAEH Sbjct: 300 AAFATCGFGIANMVPIIFSAGGNQEGMSSGTGMSVVTTMGYSGILVAPSAIGFVAEHSSF 359 Query: 365 RVSFVGVSLVMMMVALFGPRAVR 387 F+ +S+++++V L A R Sbjct: 360 GPIFIAMSVLLIVVLLMAGLAHR 382 >SMc03889 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 379 Score = 162 bits (411), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 123/370 (33%), Positives = 190/370 (51%), Gaps = 17/370 (4%) Query: 27 FFVNGATFATWGVLIPSVKERFDLSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 86 F +NG +W IP KER + ++VL L +L G+L+ M +G +IAR+GS + + Sbjct: 12 FLMNGFVTGSWAPKIPEFKERLGIGESVLGLLILGFGIGSLVLMPIAGGFIARLGSQKVV 71 Query: 87 RQVGILYAATLLLIPLAPQFWMLVALLLVFGSAMAAFDVAMSVQAALVEGRRTRPIMSTL 146 + I+ + LLL+ L P W + + G + A DVAM+ A VE R IMS+ Sbjct: 72 KVTAIILSPLLLLLTLLPNLWTAALGMFLLGGFVGAMDVAMNANAVEVEKSMRRAIMSSC 131 Query: 147 HAMFSIGGIAGSA----LGAVPGLSPLAHAALVAAMTLAVALSIGPFALPDDTHDDTSAT 202 HA +S+GG+ G+ L A G+ P HA +V + LA+ P L D H Sbjct: 132 HAYWSLGGLIGAGIGGFLMARFGVLP--HAIVVTCLCLAILAVAWPMILADRPH------ 183 Query: 203 PEGDHSARRMVL-----VLGVIAFLALMCEGGMYDWAAVYMRDIAQSPVAWVSYSYAAFS 257 P R+ + ++G++A +++ EG + DW A+Y++D + V + +AAFS Sbjct: 184 PAATREKLRLPMTPLPWLIGIMALFSMVPEGAVLDWGALYLKDELGASVELSGFGFAAFS 243 Query: 258 TGMALGRLTGDRIRERIGGLRTLAWSGVAGATGIALAAAWPSPLATMAGLLLAGLGIANL 317 MA R GD +R+R+G TL V G+ LA P+ + + G LAG+GI+N+ Sbjct: 244 ATMAAMRFAGDHVRDRLGATLTLRICTVTALAGMVLAGLAPNAVLAILGFALAGIGISNM 303 Query: 318 MPIFFLAAARVPGMAAAQSIAAVARFAYVGMLLGPVCIGGVAEHLGLRVSFVGVSLVMMM 377 +PI F AA +PG+ ++ Y GML P IG +AEH G + F V ++ ++ Sbjct: 304 VPIAFSAAGNMPGLQPGIGLSVATTMGYSGMLFAPSLIGFIAEHSGFAIIFACVPVLFIV 363 Query: 378 VALFGPRAVR 387 V L AV Sbjct: 364 VLLLSHHAVH 373 >BMEI0267 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 397 Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 109/347 (31%), Positives = 167/347 (48%), Gaps = 11/347 (3%) Query: 27 FFVNGATFATWGVLIPSVKERFDLSDAVLSLAMLAVAGGALLTMGQSGKWIARVGSARAL 86 F +NG F W IP ER L A + L +L G+L M +G A GS + Sbjct: 29 FLMNGYIFGGWAPKIPEFAERLGLDSAGMGLMILVCGLGSLAMMPVAGALSAHRGSGIVV 88 Query: 87 RQVGILYAATLLLIPLAPQFWMLVALLLVFGSAMAAFDVAMSVQAALVEGRRTRPIMSTL 146 R + + LL+I L P V ++L FG MAA DV+M+ A VE + R IMS+ Sbjct: 89 RIFALAFIPALLIITLVPNVVTAVIVMLYFGGTMAAMDVSMNANAVAVEKKMRRAIMSSC 148 Query: 147 HAMFSIGGIAGSALGA--VPGLSPLAHAALVAAMTLAVALSIGPFALPDDTHDDTSATPE 204 HA +S+GG+ G+A G + + HA + + + P +PD H P+ Sbjct: 149 HAFWSLGGLIGAATGGFLIAQFGSIVHALVTMIAATILIIVAWPSIIPDTEHHH----PD 204 Query: 205 GDHSA-----RRMVLVLGVIAFLALMCEGGMYDWAAVYMRDIAQSPVAWVSYSYAAFSTG 259 G+ + ++GV+A +++ EG + DW A +MR + V + +AAFS Sbjct: 205 GEKQKLALPRNPLPWLVGVMALFSMVPEGAILDWGAYHMRQDLGASVTVAGFGFAAFSGS 264 Query: 260 MALGRLTGDRIRERIGGLRTLAWSGVAGATGIALAAAWPSPLATMAGLLLAGLGIANLMP 319 MA+ R GD +R+R G ++TL G+ + S + G + G+GI+N++P Sbjct: 265 MAVMRFAGDLVRDRFGAVKTLRACTAIAIIGMLIVGFGNSSATAIIGFAICGIGISNMVP 324 Query: 320 IFFLAAARVPGMAAAQSIAAVARFAYVGMLLGPVCIGGVAEHLGLRV 366 I F A +PG+ + ++ Y GML+ P IG VA H G V Sbjct: 325 IAFSMAGNMPGVNPSVGLSIATTLGYSGMLVAPSLIGFVARHSGFGV 371