BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0768.p (412 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Zfsr [GEPR] COG0477 Permeases of the major facilitator superfami... 444 e-124 ECs0532 [GEPR] COG0477 Permeases of the major facilitator superf... 444 e-124 YPO3093 [GEPR] COG0477 Permeases of the major facilitator superf... 444 e-124 fsr [GEPR] COG0477 Permeases of the major facilitator superfamil... 443 e-124 RSp0412 [GEPR] COG0477 Permeases of the major facilitator superf... 436 e-122 >Zfsr [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 406 Score = 444 bits (1142), Expect = e-124, Method: Compositional matrix adjust. Identities = 237/412 (57%), Positives = 310/412 (75%), Gaps = 9/412 (2%) Query: 1 MTSATDSTASVAASADAPASSAAIAAQPLVMSIILACGGAHLINDMIQALLPSIYPMLKT 60 M+ T A AAS +S I+ A +HL+NDMIQ+L+ +IYP+L++ Sbjct: 3 MSEQTQPVAGAAASTTKARTS---------FGILGAISLSHLLNDMIQSLILAIYPLLQS 53 Query: 61 GYGLSFTQVGLITLTFQVTASLLQPWIGMYTDRHPQPWLLPCGAVATLLGIVLLALAGSF 120 + L+F Q+G+ITLTFQ+ +SLLQP +G +TD++P PW LP G TL G+VLLALAGSF Sbjct: 54 EFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSF 113 Query: 121 EAFLLAAALIGIGSSTFHPEASRIARMASGGRFGLAQSTFQVGGNAGSAFGPLLAAAIVV 180 A LLAAAL+G GSS FHPE+SR+ARMASGGR GLAQS FQVGGN GS+ GPLLAA I+ Sbjct: 114 GAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIA 173 Query: 181 PYGQTNVAWFVLLSVLAIVVLSRVSAWYRGHLAAGKGRGKVRAAHQLPAATVRRALVVLA 240 PYG+ NVAWFVL ++LAIVVL+++S WY KG+ K + LP V A+ +L Sbjct: 174 PYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILL 233 Query: 241 LLVFSKYFYMASFTSYFTFYLIERFQMSVASSQLYLFLFLAAVAVGTFVGGPIGDRIGRK 300 +L+FSKYFYMAS +SY+TFYL+++F +S+ ++QL+LF FL AVA GT +GGP+GD+IGRK Sbjct: 234 ILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRK 293 Query: 301 LVIWISILGAAPFALMLPHANLFWTAVLSVLIGLIISSAFSAIVVYAQELVPGKVGMIAG 360 VIW SILG APF L+LP+A+L WT VL+V+IG I++SAFSAI+VYAQEL+PG++GM++G Sbjct: 294 YVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSG 353 Query: 361 VFFGLMFGFGGIGAALLGHLADLYGIAWVYGLCAFLPLAGLLTVLLPDVRER 412 +FFG FG GG+GAA+LG +AD I VY +CAFLPL G+LT+ LPD R + Sbjct: 354 LFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLLGMLTIFLPDNRHK 405 >ECs0532 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 406 Score = 444 bits (1142), Expect = e-124, Method: Compositional matrix adjust. Identities = 237/412 (57%), Positives = 310/412 (75%), Gaps = 9/412 (2%) Query: 1 MTSATDSTASVAASADAPASSAAIAAQPLVMSIILACGGAHLINDMIQALLPSIYPMLKT 60 M+ T A AAS +S I+ A +HL+NDMIQ+L+ +IYP+L++ Sbjct: 3 MSEQTQPVAGAAASTTKARTS---------FGILGAISLSHLLNDMIQSLILAIYPLLQS 53 Query: 61 GYGLSFTQVGLITLTFQVTASLLQPWIGMYTDRHPQPWLLPCGAVATLLGIVLLALAGSF 120 + L+F Q+G+ITLTFQ+ +SLLQP +G +TD++P PW LP G TL G+VLLALAGSF Sbjct: 54 EFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSF 113 Query: 121 EAFLLAAALIGIGSSTFHPEASRIARMASGGRFGLAQSTFQVGGNAGSAFGPLLAAAIVV 180 A LLAAAL+G GSS FHPE+SR+ARMASGGR GLAQS FQVGGN GS+ GPLLAA I+ Sbjct: 114 GAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFGSSLGPLLAAVIIA 173 Query: 181 PYGQTNVAWFVLLSVLAIVVLSRVSAWYRGHLAAGKGRGKVRAAHQLPAATVRRALVVLA 240 PYG+ NVAWFVL ++LAIVVL+++S WY KG+ K + LP V A+ +L Sbjct: 174 PYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILL 233 Query: 241 LLVFSKYFYMASFTSYFTFYLIERFQMSVASSQLYLFLFLAAVAVGTFVGGPIGDRIGRK 300 +L+FSKYFYMAS +SY+TFYL+++F +S+ ++QL+LF FL AVA GT +GGP+GD+IGRK Sbjct: 234 ILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRK 293 Query: 301 LVIWISILGAAPFALMLPHANLFWTAVLSVLIGLIISSAFSAIVVYAQELVPGKVGMIAG 360 VIW SILG APF L+LP+A+L WT VL+V+IG I++SAFSAI+VYAQEL+PG++GM++G Sbjct: 294 YVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFSAILVYAQELLPGRIGMVSG 353 Query: 361 VFFGLMFGFGGIGAALLGHLADLYGIAWVYGLCAFLPLAGLLTVLLPDVRER 412 +FFG FG GG+GAA+LG +AD I VY +CAFLPL G+LT+ LPD R + Sbjct: 354 LFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLLGMLTIFLPDNRHK 405 >YPO3093 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 404 Score = 444 bits (1141), Expect = e-124, Method: Compositional matrix adjust. Identities = 234/382 (61%), Positives = 302/382 (79%), Gaps = 1/382 (0%) Query: 32 SIILACGGAHLINDMIQALLPSIYPMLKTGYGLSFTQVGLITLTFQVTASLLQPWIGMYT 91 SI+ A +HL+NDMIQ+L+ +IYP+L+ + LSF Q+GLITLT+Q+TASLLQP IG+YT Sbjct: 23 SILGAISVSHLLNDMIQSLILAIYPLLQAEFSLSFAQIGLITLTYQLTASLLQPLIGLYT 82 Query: 92 DRHPQPWLLPCGAVATLLGIVLLALAGSFEAFLLAAALIGIGSSTFHPEASRIARMASGG 151 D+HPQP+ LP G TL GI+LLA+A +F LLAAAL+G GSS FHPE+SR+ARMASGG Sbjct: 83 DKHPQPYSLPIGMGFTLSGILLLAVATTFPVVLLAAALVGTGSSVFHPESSRVARMASGG 142 Query: 152 RFGLAQSTFQVGGNAGSAFGPLLAAAIVVPYGQTNVAWFVLLSVLAIVVLSRVSAWYRGH 211 R GLAQS FQVGGN GSA GPLLAA I+ PYG+ NV WF L ++LAIVVL +VS WY+ Sbjct: 143 RHGLAQSVFQVGGNFGSALGPLLAAIIIAPYGKGNVGWFSLAALLAIVVLLQVSKWYKLQ 202 Query: 212 LAAGKGRG-KVRAAHQLPAATVRRALVVLALLVFSKYFYMASFTSYFTFYLIERFQMSVA 270 A G+ K+ +A LP + L +L +L+FSKYFY+ S +SY+TFYLI +F +SV Sbjct: 203 QRASYGKVLKISSAKTLPKNKIISTLAILMVLIFSKYFYLTSISSYYTFYLIHKFGVSVQ 262 Query: 271 SSQLYLFLFLAAVAVGTFVGGPIGDRIGRKLVIWISILGAAPFALMLPHANLFWTAVLSV 330 S+Q++LF+FL AVA GT +GGP+GD+IGRK VIW SILG APF L LP+A+L+WT +L+V Sbjct: 263 SAQIHLFVFLFAVAAGTIIGGPLGDKIGRKYVIWGSILGVAPFTLALPYASLYWTGILTV 322 Query: 331 LIGLIISSAFSAIVVYAQELVPGKVGMIAGVFFGLMFGFGGIGAALLGHLADLYGIAWVY 390 IG+I++SAFSAI+VYAQEL+PGKVGM++G+FFG FG GGIGAA+LG++ADL I VY Sbjct: 323 FIGVILASAFSAILVYAQELIPGKVGMVSGLFFGFAFGMGGIGAAVLGYVADLTSIELVY 382 Query: 391 GLCAFLPLAGLLTVLLPDVRER 412 +CAFLPL G+ T LLP++ ++ Sbjct: 383 QICAFLPLLGIFTALLPNLDDK 404 >fsr [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 406 Score = 443 bits (1139), Expect = e-124, Method: Compositional matrix adjust. Identities = 228/373 (61%), Positives = 298/373 (79%) Query: 40 AHLINDMIQALLPSIYPMLKTGYGLSFTQVGLITLTFQVTASLLQPWIGMYTDRHPQPWL 99 +HL+NDMIQ+L+ +IYP+L++ + L+F Q+G+ITLTFQ+ +SLLQP +G +TD++P PW Sbjct: 33 SHLLNDMIQSLILAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWS 92 Query: 100 LPCGAVATLLGIVLLALAGSFEAFLLAAALIGIGSSTFHPEASRIARMASGGRFGLAQST 159 LP G TL G+VLLALAGSF A LLAAAL+G GSS FHPE+SR+ARMASGGR GLAQS Sbjct: 93 LPIGMCFTLSGLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSI 152 Query: 160 FQVGGNAGSAFGPLLAAAIVVPYGQTNVAWFVLLSVLAIVVLSRVSAWYRGHLAAGKGRG 219 FQVGGN GS+ GPLLAA I+ PYG+ NVAWFVL ++LAIVVL+++S WY KG+ Sbjct: 153 FQVGGNFGSSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKP 212 Query: 220 KVRAAHQLPAATVRRALVVLALLVFSKYFYMASFTSYFTFYLIERFQMSVASSQLYLFLF 279 K + LP V A+ +L +L+FSKYFYMAS +SY+TFYL+++F +S+ ++QL+LF F Sbjct: 213 KATIINPLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAF 272 Query: 280 LAAVAVGTFVGGPIGDRIGRKLVIWISILGAAPFALMLPHANLFWTAVLSVLIGLIISSA 339 L AVA GT +GGP+GD+IGRK VIW SILG APF L+LP+A+L WT VL+V+IG I++SA Sbjct: 273 LFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASA 332 Query: 340 FSAIVVYAQELVPGKVGMIAGVFFGLMFGFGGIGAALLGHLADLYGIAWVYGLCAFLPLA 399 FSAI+VYAQEL+PG++GM++G+FFG FG GG+GAA+LG +AD I VY +CAFLPL Sbjct: 333 FSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL 392 Query: 400 GLLTVLLPDVRER 412 G+LT+ LPD R + Sbjct: 393 GMLTIFLPDNRHK 405 >RSp0412 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 411 Score = 436 bits (1122), Expect = e-122, Method: Compositional matrix adjust. Identities = 239/383 (62%), Positives = 305/383 (79%), Gaps = 3/383 (0%) Query: 33 IILACGGAHLINDMIQALLPSIYPMLKTGYGLSFTQVGLITLTFQVTASLLQPWIGMYTD 92 +I A AH +NDM+Q+L+ +IYP+LK + L FTQ+GLITLT+Q+TASLLQP +G+YTD Sbjct: 24 VIGAISFAHFLNDMMQSLILAIYPLLKGNFHLDFTQIGLITLTYQITASLLQPMVGLYTD 83 Query: 93 RHPQPWLLPCGAVATLLGIVLLALAGSFEAFLLAAALIGIGSSTFHPEASRIARMASGGR 152 RHP+P+ LP G TL+G++L+++A +F LLAAAL+G GSS FHPE+SR+ARMASGGR Sbjct: 84 RHPKPYSLPVGMGFTLVGLLLMSVAPNFGTLLLAAALVGTGSSIFHPESSRVARMASGGR 143 Query: 153 FGLAQSTFQVGGNAGSAFGPLLAAAIVVPYGQTNVAWFVLLSVLAIVVLSRVSAWYRGHL 212 GLAQS FQVGGN GSA GPLLAAA+++PYGQ ++AWF + +++A+VVL V WYR Sbjct: 144 HGLAQSLFQVGGNVGSAMGPLLAAAVIMPYGQHSLAWFSIAALVAMVVLYHVGGWYRRER 203 Query: 213 AAGKGRGKVRAAHQLPA---ATVRRALVVLALLVFSKYFYMASFTSYFTFYLIERFQMSV 269 AAG+GR AH V +A+++L +L+FSKYFY+AS SY+TFYLI +F +S Sbjct: 204 AAGQGRKAGARAHAAARLPAGKVVKAMLLLVVLLFSKYFYLASLNSYYTFYLISKFHLSA 263 Query: 270 ASSQLYLFLFLAAVAVGTFVGGPIGDRIGRKLVIWISILGAAPFALMLPHANLFWTAVLS 329 +SQL+LFLFL +VA GT GGPIGDR GRK+VIW+SILG APF L+LPHANLFWTAVL+ Sbjct: 264 QASQLFLFLFLFSVAAGTIAGGPIGDRFGRKVVIWVSILGVAPFTLLLPHANLFWTAVLT 323 Query: 330 VLIGLIISSAFSAIVVYAQELVPGKVGMIAGVFFGLMFGFGGIGAALLGHLADLYGIAWV 389 V+IGL+++SAFSAI+VYAQEL+PG+VGM++G+FFG FG GGIGAA+LG LAD GI V Sbjct: 324 VVIGLVLASAFSAILVYAQELIPGQVGMVSGLFFGFAFGLGGIGAAVLGRLADATGIDHV 383 Query: 390 YGLCAFLPLAGLLTVLLPDVRER 412 Y LC+FLPL GLLTV LPD+ R Sbjct: 384 YHLCSFLPLIGLLTVFLPDIERR 406