BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0734.p (437 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 593 e-169 RSp0536 [GEPR] COG0477 Permeases of the major facilitator superf... 343 6e-94 RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 311 3e-84 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 304 3e-82 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 283 5e-76 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 593 bits (1529), Expect = e-169, Method: Compositional matrix adjust. Identities = 302/422 (71%), Positives = 360/422 (85%), Gaps = 2/422 (0%) Query: 6 SKQRQVIAAIVGNALEWYDFIVYGFFSAIIARLFFPADNEYTSLLVALATFGIGFFMRPV 65 S+ RQV AA++GNALEWYDFIVYGF S++IARLFFP+ +EYTSLL+ALATFG+GFFMRPV Sbjct: 9 SRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVGFFMRPV 68 Query: 66 GGVLLGLYADRKGRKAAMQVIIVLMTLAIAIIAFTPTYATIGIAAPIMIVVARMLQGFAT 125 GGVLLGLYADR+GRKAAMQ+II+LMTL+IA+IAF PTYA IG+ AP++IV+ARMLQGFAT Sbjct: 69 GGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARMLQGFAT 128 Query: 126 GGEYSSSTAFLVESAPANQRGLYGSWQLVGQCLAVFCGAGMGALVTRNLSPQALDNWGWR 185 GGEY+S+TAFLVESAP ++RGLYGSWQL GQCLAVF GAGMGALVT L +AL++WGWR Sbjct: 129 GGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEALESWGWR 188 Query: 186 LPFVIGLLIGPVGLWIRRHMHETDDFMESANKPDAAPIKLLDVVKTNLRGVLVSMGQVIN 245 +PF+ GLLIGPVGLWIRR+M ET+ F+E+ +P LL V++ R VLVSMG + Sbjct: 189 VPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQ-GLLGVLREYRRSVLVSMGLTVV 247 Query: 246 GTVAFYVVLVNMPTFANKQLGLPLDQAFMVQMIAVALLTLIIPFAGALSDRIGRRTVLLY 305 GTV+FYVVLVNMPTFA+KQLGLPLD+ FMVQM AVAL+TL+IP AG LSDR+GRR VLL Sbjct: 248 GTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRRPVLLV 307 Query: 306 SSLAFLLTVYPLFVWVATAPSLPRLLVMQVLLCIMIGANYGPMPTALSEQFPTRVRSTGL 365 ++LAF+L VYPLF WVA APSL RLL+MQ+LLC IG +GP PTA++EQFP RVRSTGL Sbjct: 308 ATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRVRSTGL 367 Query: 366 AVAYNLAAMLFGGFAPFIVTWLTKTSGSPVAPAWYVLLAACIGVAAAWAMRD-QSPAAKN 424 AVAYNLA MLFGGFAPFIVTWLT+ GSPVAPA+YVL AA +G+ A +R+ +PA + Sbjct: 368 AVAYNLAVMLFGGFAPFIVTWLTEVGGSPVAPAFYVLGAAFLGLLATLYLREGATPAPRP 427 Query: 425 RQ 426 R+ Sbjct: 428 RE 429 >RSp0536 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 441 Score = 343 bits (879), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 186/407 (45%), Positives = 263/407 (64%), Gaps = 2/407 (0%) Query: 2 QPQLSKQRQVIA-AIVGNALEWYDFIVYGFFSAIIARLFFPADNEYTSLLVALATFGIGF 60 Q L +QR +A AI+GNA EW+DF +YGFF+ +IA + FP+ N +T+LL+A+ATFG+GF Sbjct: 12 QTSLPRQRHAVATAILGNAFEWFDFTLYGFFAPVIATVLFPSANPFTALLLAIATFGVGF 71 Query: 61 FMRPVGGVLLGLYADRKGRKAAMQVIIVLMTLAIAIIAFTPTYATIGIAAPIMIVVARML 120 RP+GG++LG+YADR+GR+ A+ + +LM L A+IA PTYA GIAAP++ V+AR+L Sbjct: 72 VTRPLGGIVLGIYADRRGRRPALALSALLMALGTALIAIAPTYAQAGIAAPVIAVIARLL 131 Query: 121 QGFATGGEYSSSTAFLVESAPANQRGLYGSWQLVGQCLAVFCGAGMGALVTRNLSPQALD 180 QGF+ GGE +TA+L E AP +R Y SW LA+ CGA +G L T L +AL Sbjct: 132 QGFSAGGEMGGATAYLNEIAPPGKRAFYTSWIQASVGLAIVCGAMLGTLATSLLDAEALR 191 Query: 181 NWGWRLPFVIGLLIGPVGLWIRRHMHETDDFMESANKPDAAPIKLLDVVKTNLRGVLVSM 240 WGWR+PF +G+LIGP+G IR + ET F +A + A LL+VV+ + R VL+ Sbjct: 192 AWGWRIPFALGVLIGPIGYVIRSRLDETPAFARAATEARADS-PLLEVVRRHRRAVLIGA 250 Query: 241 GQVINGTVAFYVVLVNMPTFANKQLGLPLDQAFMVQMIAVALLTLIIPFAGALSDRIGRR 300 VI TV YV+L M T+A L LP F M + + L P G L+DR+G + Sbjct: 251 SIVILWTVCTYVLLFYMQTYAIHVLKLPSSAGFAGSMASGVTMMLTAPLFGWLADRLGYQ 310 Query: 301 TVLLYSSLAFLLTVYPLFVWVATAPSLPRLLVMQVLLCIMIGANYGPMPTALSEQFPTRV 360 VL ++LA L+ YPL+ ++ AP+ L+ +Q++ ++ A GP+P A ++ FPT+V Sbjct: 311 RVLSGAALAILVLAYPLYAYLNHAPAAGTLIGVQIVFGLLSAAYTGPIPVAFADLFPTKV 370 Query: 361 RSTGLAVAYNLAAMLFGGFAPFIVTWLTKTSGSPVAPAWYVLLAACI 407 STGL+ AYNL ML GGFAPF +TWL+ +AP YV++AA + Sbjct: 371 LSTGLSTAYNLTVMLIGGFAPFYLTWLSHAFDPMLAPVLYVMVAALV 417 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 311 bits (796), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 166/428 (38%), Positives = 248/428 (57%), Gaps = 4/428 (0%) Query: 2 QPQLSKQRQVIAAIVGNALEWYDFIVYGFFSAIIARLFFPADNEYTSLLVALATFGIGFF 61 P SK R + + GN LE YDF+VYG+++ IA FFPADNE+ SL+++L TFG+GF Sbjct: 5 NPNESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFL 64 Query: 62 MRPVGGVLLGLYADRKGRKAAMQVIIVLMTLAIAIIAFTPTYATIGIAAPIMIVVARMLQ 121 MRP+G ++LG Y DR GR+A + + + LM +IA P YATIG+AAP+++++ R+LQ Sbjct: 65 MRPLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQ 124 Query: 122 GFATGGEYSSSTAFLVESAPANQRGLYGSWQLVGQCLAVFCGAGMGALVTRNLSPQALDN 181 GF+ G E + +L E + ++G + SWQ Q +AV A +G L++ LSP+ + Sbjct: 125 GFSAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGE 184 Query: 182 WGWRLPFVIGLLIGPVGLWIRRHMHETDDFMESANKPDAAPIKLLDVVKTNLRGVLVSMG 241 WGWR+PF++G LI P IRR + ET++F + ++P I + N R V Sbjct: 185 WGWRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEI--FRSMGENWRLVGAGTL 242 Query: 242 QVINGTVAFYVVLVNMPTFANKQLGLPLDQAFMVQMIAVALLTLIIPFAGALSDRIGRRT 301 V+ TV+FY++ PTF L L + +V + A +P G++SDRIGRR Sbjct: 243 LVVMTTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRP 302 Query: 302 VLLYSSLAFLLTVYPLFVWVATAPSLPRLLVMQVLLCIMIGANYGPMPTALSEQFPTRVR 361 +L+ + LLT YP W+ PS RLL +++ L + G+ G M L+E P VR Sbjct: 303 LLITFTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVR 362 Query: 362 STGLAVAYNLAAMLFGGFAPFIVTWLTKTSGSPVAPAWYVLLAACIGVAAAWAMRDQSPA 421 +TG ++AY+LA +FGGF P I TWL +G+ P ++ AA G+ A + PA Sbjct: 363 TTGFSLAYSLATAIFGGFTPAIATWLIHATGNKAMPGLWLSFAAICGLVATLIV--VKPA 420 Query: 422 AKNRQTEV 429 ++ T V Sbjct: 421 GRHVHTTV 428 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 304 bits (778), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 163/419 (38%), Positives = 242/419 (57%), Gaps = 2/419 (0%) Query: 2 QPQLSKQRQVIAAIVGNALEWYDFIVYGFFSAIIARLFFPADNEYTSLLVALATFGIGFF 61 P SK R + + GN LE +DF+VYG+++ IA FFPA N + SL+++L TFG GF Sbjct: 5 NPNESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFL 64 Query: 62 MRPVGGVLLGLYADRKGRKAAMQVIIVLMTLAIAIIAFTPTYATIGIAAPIMIVVARMLQ 121 MRP+G ++LG Y DR GR+A + + +VLM +IA P Y TIG+AAP+++++ R+LQ Sbjct: 65 MRPLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQ 124 Query: 122 GFATGGEYSSSTAFLVESAPANQRGLYGSWQLVGQCLAVFCGAGMGALVTRNLSPQALDN 181 GF+ GGE + +L E A ++G Y SWQ Q +AV A +G L++ LSP+ + Sbjct: 125 GFSAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGE 184 Query: 182 WGWRLPFVIGLLIGPVGLWIRRHMHETDDFMESANKPDAAPIKLLDVVKTNLRGVLVSMG 241 WGWR+PF+IG LI P +IRR + ET++F + ++P +LL + N R Sbjct: 185 WGWRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMG--ELLRSMGENWRLAGAGTL 242 Query: 242 QVINGTVAFYVVLVNMPTFANKQLGLPLDQAFMVQMIAVALLTLIIPFAGALSDRIGRRT 301 + TV+FY++ PTF L + + +V + A + +P G+LSDRIGRRT Sbjct: 243 LAVMTTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRT 302 Query: 302 VLLYSSLAFLLTVYPLFVWVATAPSLPRLLVMQVLLCIMIGANYGPMPTALSEQFPTRVR 361 L+ S LLT YP W+ PS RLL +++ L + G G M L+E P ++R Sbjct: 303 PLIVFSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLR 362 Query: 362 STGLAVAYNLAAMLFGGFAPFIVTWLTKTSGSPVAPAWYVLLAACIGVAAAWAMRDQSP 420 +TG ++AY+LA +FGGF P I T L +G+ P ++ AA G+ A + P Sbjct: 363 TTGFSLAYSLATAIFGGFTPAIATGLIHATGNKAMPGLWLSFAAICGLVATLTVVKPQP 421 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 283 bits (724), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 148/395 (37%), Positives = 223/395 (56%), Gaps = 2/395 (0%) Query: 17 GNALEWYDFIVYGFFSAIIARLFFPADNEYTSLLVALATFGIGFFMRPVGGVLLGLYADR 76 GN LE +DF ++GF++ IAR FFPA++E+ SL++ A FG GF MRPVG ++LG Y DR Sbjct: 23 GNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFGSGFLMRPVGAIVLGAYIDR 82 Query: 77 KGRKAAMQVIIVLMTLAIAIIAFTPTYATIGIAAPIMIVVARMLQGFATGGEYSSSTAFL 136 GR+ + V + +M +IA P Y TIG+AAP ++++ R+LQGF+ G E + +L Sbjct: 83 IGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLGRLLQGFSAGVELGGVSVYL 142 Query: 137 VESAPANQRGLYGSWQLVGQCLAVFCGAGMGALVTRNLSPQALDNWGWRLPFVIGLLIGP 196 E A +G Y SWQ Q +A+ A +G + L A+ WGWR+PF IG +I P Sbjct: 143 SEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHDAISEWGWRIPFFIGCMIIP 202 Query: 197 VGLWIRRHMHETDDFMESANKPDAAPIKLLDVVKTNLRGVLVSMGQVINGTVAFYVVLVN 256 + +RR + ET+ F++ ++PD I + N R + V T FY + V Sbjct: 203 LIFVLRRSLQETEAFLQRKHRPDTREI--FATIAKNWRIITAGTLLVAMTTTTFYFITVY 260 Query: 257 MPTFANKQLGLPLDQAFMVQMIAVALLTLIIPFAGALSDRIGRRTVLLYSSLAFLLTVYP 316 PT+ L L + +V M+ + +P GA+SDRIGRR VL+ +L L+T +P Sbjct: 261 TPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGRRAVLMGITLLALITTWP 320 Query: 317 LFVWVATAPSLPRLLVMQVLLCIMIGANYGPMPTALSEQFPTRVRSTGLAVAYNLAAMLF 376 + W+ AP R+ ++ + G G M AL+E P VR+ G ++A++LA +F Sbjct: 321 VMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVYVRTVGFSLAFSLATAIF 380 Query: 377 GGFAPFIVTWLTKTSGSPVAPAWYVLLAACIGVAA 411 GG P I T L K +G +P W+++ AA G+AA Sbjct: 381 GGLTPAISTALVKLTGDKSSPGWWLMCAALCGLAA 415