BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0725.p (1157 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1190 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta ... 840 0.0 BMEI2023 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta... 232 4e-60 AGc39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta su... 224 8e-58 SMc02760 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta... 213 3e-54 BS_addA [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta ... 167 2e-40 >RSc1190 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Rso Ralstonia solanacearum Length = 1177 Score = 840 bits (2169), Expect = 0.0, Method: Compositional matrix adjust. Identities = 524/1188 (44%), Positives = 698/1188 (58%), Gaps = 84/1188 (7%) Query: 10 AYEVNGKPVAAEVFTREACDPRHSVVVEACAGSGKTWLLVARMLRLLLSGAQAPELLAIT 69 AYE +G PV+ E F+R ACDP SVVVEACAGSGKTWLLV RMLRLLL+GA ++LAIT Sbjct: 5 AYERDGAPVSPEAFSRAACDPLRSVVVEACAGSGKTWLLVTRMLRLLLAGAAPSDILAIT 64 Query: 70 FTRKAAQEMRERLLELLHELALADEHHAASLLRERGVAEADLPRLLPLARGLYERILSSE 129 FTRKAA+EMR+RLL+ L +LA AD+ L R V E + P L+ +ARGLY R+L S Sbjct: 65 FTRKAAEEMRQRLLDSLAQLAGADDAAVVRELVARTVDEREAPGLVAVARGLYGRVLESP 124 Query: 130 QSLSIDTFHSWFARLLQIALLASGVPHGYTLTEKNGELLEEAYRRFMQTLREPEGAIVKA 189 ++IDTFH WF LL+ A L+SGVP G +L E G L EA+ F + L E A ++A Sbjct: 125 SRMAIDTFHGWFGGLLRGAPLSSGVPQGASLREDAGRLRREAWAPFWRRLLAEEHAELRA 184 Query: 190 ALLELYELVGDFNTRQLLDAFIDKRAEWWAATQDDGEEAEPSPLRWLEALCGDDARRDAR 249 A L +LVGDF +LLDA +R++WWA G PL L+ L GDDA D Sbjct: 185 AYDTLVDLVGDFQAGRLLDAMFAQRSDWWAYKAQAGAH----PLGPLDDLLGDDAHTDPL 240 Query: 250 LALWDDAPLVARASQVAVLLGQGGSLNKNRAVAIESALTAGPALE---------HFDALY 300 + DA L+A +V+ LGQGG+ RAV IE+A+TA AL+ F+AL+ Sbjct: 241 IEALQDAALLADMLRVSGWLGQGGAAEGKRAVQIETAVTAARALDLSDAAARRHAFEALF 300 Query: 301 SQFFDDKDKPRKNGKVKSLLAALTQHFAASDEAALAAFEDEFNAIGEALRKLQGRSKEKL 360 + F KPR K+L+ A+ + A + D + EAL Q R E Sbjct: 301 TAFHTQAGKPRACKPTKALVKAIGEDAAQT-------LADLHAVLCEALAVYQARRHESR 353 Query: 361 VLQLNRALFAAGRAYLDCYQEVKSEQRVLDFADLEWQAYRLLKDDASAAYLQTRLDARYK 420 V +N ALF G A ++ YQ K + R +DF DLEW+A RL++D+ +AAYLQ RLDARYK Sbjct: 354 VRAINAALFTLGDALIERYQAYKRQARAMDFTDLEWEAARLMRDEDTAAYLQVRLDARYK 413 Query: 421 HILLDEFQDTNPLQWCIVRCWLDAYGGDAAQPSVFVVGDPKQSIYRFRRAEPRVFVAARE 480 H+LLDEFQDTNP+QW I++ WL Y G +P+VF+VGDPKQSIYRFRRA+ R+F AAR+ Sbjct: 414 HLLLDEFQDTNPMQWRILQGWLRGYEGTGTRPTVFLVGDPKQSIYRFRRADARLFEAARD 473 Query: 481 LLRSQ-GAAILRANQTRRNASAVVNVLNRSFI----RGGNPLFAQQTT-LGLAGGEVWRL 534 +L + A +LR N+TRRNA AV+ +N F+ RG P++A+Q+T + G L Sbjct: 474 MLVAAFDATVLRTNRTRRNAPAVLEWVNAVFLLARARGDYPIYAEQSTAVDAPVGRALLL 533 Query: 535 PLVRQEEGEENVTRPETDAESASAAASSAASEGEQDIIAWRNPLTTPRGEEEDARRLLEG 594 PLV E + D A R+ LT PR E D++R EG Sbjct: 534 PLVPVPEA------------------------AQADETAPRDSLTEPREEAGDSQRYDEG 569 Query: 595 QALAQALLKAYREVPVITGKSERAMRWGDIMLLVRKRTHLAAYESALRAAGIPFISDKRG 654 + +A L + V +ER +RW D LLVR++ +LA YE ALR AG+P++S +RG Sbjct: 570 RQVAACLRALHAGERVRENGAERPVRWSDFQLLVRRKRYLADYERALRDAGVPYLSPRRG 629 Query: 655 GLLESLEIADLIALLTFLITPNDTRALAHVLKSPIIGAADDDLVQIARRAAHAEGGHWWQ 714 GLL +LE DL ALL FL+TP LAHVL+SPI DDDL+ +A+ A WW+ Sbjct: 630 GLLATLEALDLCALLDFLMTPQADLPLAHVLRSPIFAVTDDDLIALAQAGEGASAPTWWE 689 Query: 715 HLQAMQQEGAASAALVRAVTLLQRWLQAAPHLPVHDLLDRILHQGELVARYAQNASPLTR 774 L A+ A+A RA LL RWL AP LPVHDLLD I++ GEL RYA+ R Sbjct: 690 RLAALADRPHAAAQWRRAHRLLSRWLAVAPTLPVHDLLDHIVYTGELKRRYAERVPEANR 749 Query: 775 SQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRTSGGDAPDEA----------SVD 824 Q L N+ AF++L+L++D GRYPSLPKF+ LR +++ ++PDE ++D Sbjct: 750 EQALANLDAFLKLALDLDGGRYPSLPKFMAELRAIRQGDEEESPDEGVQGDAAEAPDAID 809 Query: 825 A-----SADAVRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDQDAPTHFSA 879 A DAV+ILTVH++KGLEAP V +LD++HSD+ D +GIL WP +AP HFSA Sbjct: 810 AELASEGLDAVQILTVHASKGLEAPFVVLLDSHHSDTRADTVGILIDWPPGAEAPAHFSA 869 Query: 880 FGRRSERGSAREELFEQEDQLRTQEDWNLLYVAVTRAKQLLLVSGVAGKR-GTGEGGVVE 938 FG+ +ERG AR+ LF QE L +E+WNLLYVA+TRA+Q L+VSGVA KR G V E Sbjct: 870 FGKAAERGRARDPLFAQEATLAERENWNLLYVAMTRARQALIVSGVANKRDGAAAQAVDE 929 Query: 939 G---------SWYQRLFASDAPVREIGEEAVQGADVAAVEEVFSLSLFDPRPQPMLLFGA 989 G SWY L A+ EA GA A +++ D R P+ + Sbjct: 930 GDVPDVDGSASWYT-LLATAGAATPAPVEAAAGAGGADHAASQAVAYHDFR-VPLTVTVR 987 Query: 990 ADGEQEQTPPAIADDGTLVSNEAIDEGVALHALLERLTHANAWPLTLPAPPTLVRWLGVS 1049 G E+ A + A+ +G LHA+LERLT + P +P + RW G + Sbjct: 988 IGGAVERVADAPDTADAIFDQGAVAQGELLHAVLERLTR-HGKPEQVPDAAAIARWFGAT 1046 Query: 1050 ----AEMAQVVHAQARVVLAQPQLERFFNPALHRWARNEMEIVTPAG-VLRLDRVVMFEE 1104 A+ A+ A R +LA L F+PA A NE+E+ +P G +LR+DR++ + Sbjct: 1047 GITDADAARATEA-VRRMLAAEALAHVFDPARFDVAHNEVELFSPDGALLRIDRLIERGD 1105 Query: 1105 EVWVLDYKRRLLDSERAEYAAQLARYRSALVSVFSDKRIRSALITADG 1152 EV V+DYK RLL ERA YA QL Y +A+ ++ + +R+ + TA G Sbjct: 1106 EVLVVDYKLRLLPVERAAYADQLRGYAAAVAPIYPGRAVRAGVATAQG 1153 >BMEI2023 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Bme Brucella melitensis Length = 1180 Score = 232 bits (592), Expect = 4e-60, Method: Compositional matrix adjust. Identities = 323/1212 (26%), Positives = 500/1212 (41%), Gaps = 173/1212 (14%) Query: 27 ACDPRHSVVVEACAGSGKTWLLVARMLRLLLSGAQAPELLAITFTRKAAQEMRERLLELL 86 A DP SV V A AGSGKT +L R++RLLL G ++L +T+T+ AA M+ R+ L Sbjct: 18 AADPSASVWVSANAGSGKTHVLTERVIRLLLEGTDPSKILCLTYTKAAAAVMQNRVFMRL 77 Query: 87 HELA-LADEHHAASL--LRERGVAEADLPRLLPLARGLYERILSSEQSLSIDTFHSWFAR 143 E A L DE A L L R A + AR L+ R L + + I T H++ Sbjct: 78 SEWAVLPDEALAERLEKLERRRPGAARVAS----ARRLFARALKTPGGMKIQTIHAFCEA 133 Query: 144 LLQIALLASGVPHGYTLTEK--NGELLEEAYRRFMQTLREPEGAIVKAALLELYELVGDF 201 +L L + + + + + L+ EA R ++T + AA ++ + G+ Sbjct: 134 ILHQFPLEANIAGHFEMMDDLMQAALVGEARRTLLETAYGGGDPALAAAFADVLQAAGET 193 Query: 202 NTRQLLDAFIDKR-------AEWWAATQDDGEEAEPSPLRWLEAL-----CGDDARRDAR 249 + LLD + +R AE T +EAL DAR D Sbjct: 194 GLQSLLDEAVGRRNGLQLYLAELGVGTHR------------VEALHRAFGFEPDAREDDL 241 Query: 250 LA-LWDDAPLVARASQVAVLLGQGGSLNKNRAVAIESALTAGPALEHFDALYSQFFDDKD 308 LA LW A + + + +G S ++ A+ ++ A + L + F Sbjct: 242 LADLWPVPEFSDDALDLILSIPKGASRAQDFALQLKRLEKASGLPDKIAVLRAAFLKSTG 301 Query: 309 KPRKNGKVKSLLAALTQHFAASDEAALAAFEDEFNAIGEALRKLQGRSKEKLVLQLNRAL 368 +P+ V S A+ + L FE+EF+ + R KE +++LN A Sbjct: 302 EPKSGSYVCS----------AAVKKLLPEFEEEFDTAAARVEMGLDRLKELRLVRLNLAA 351 Query: 369 FAAGRAYLDCYQEVKSEQRVLDFADLEWQAYRLLKDDASAAYLQTRLDARYKHILLDEFQ 428 L Y ++K + +LDF DL + LL + + ++Q +LD HIL+DE Q Sbjct: 352 LTLIDNLLQRYHDLKRRRGLLDFEDLITRTVALLARNGAGQWVQYKLDRGIDHILVDEAQ 411 Query: 429 DTNPLQWCIVRC----WLDAYGGDAAQPSVFVVGDPKQSIYRFRRAEPRVFVAARELLRS 484 DT+P QW ++R + G Q ++F VGD KQSIY F+ A P F Sbjct: 412 DTSPDQWQVIRMLSEEFFSGLGQRNVQRTLFAVGDEKQSIYSFQGAVPDDFA-------E 464 Query: 485 QGAAILRANQTRRNASAVVNVLNRSFIRGGNPLFAQQTTLGLAGGEVWRLPLVRQEEGEE 544 QG AI + NA ++ +F P Q +E Sbjct: 465 QGRAI---SIQASNAELKFERVSLNFSFRSTPDVLQAV--------------------DE 501 Query: 545 NVTRPETDAESASAAASSAASEGEQDIIAWRNPLTTPRGEEEDARRLLEGQALAQALLKA 604 RPE + + A SA + E I + LT EE D R+ Q A A+ A Sbjct: 502 VFARPEANRGLSGATVHSAIRDKEPGEIEIWDMLTPEMVEEPDDWRVPVDQLAAPAVRLA 561 Query: 605 YREVPVI---------TGKSERAMRWGDIMLLVRKRTH-LAAYESALRAAGIPFISDKRG 654 + I R + DIM+LVRKR + A AL+ +P R Sbjct: 562 EQIAATIRYWLDRGEPIPGQNRKIAPRDIMVLVRKRDQFMPALSRALKNLSVPVAGADRL 621 Query: 655 GLLESLEIADLIALLTFLITPNDTRALAHVLKSPIIGAADDDLVQIARRAAHAEGGHWWQ 714 L + I DL+AL F++ P+D +LA +LKSP+ G DD L +A G ++ Sbjct: 622 QLTSHIAIQDLMALGRFVLQPSDDLSLAALLKSPLFGWDDDRLFTLA--YPRGAGDTLFE 679 Query: 715 HLQAMQQEGAASAALVRAVTLLQRWLQAAPHLPVHDLLDRILH----QGELVARYAQNAS 770 +L + A L + LL RW A +PV + R+L + +L+AR A Sbjct: 680 YLYRASRH---DAELAQIHKLLSRWRNMADTMPVFEFYARVLSADGARRKLLARLGPEAG 736 Query: 771 PLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRTSGGDAPD-EASVDASADA 829 + I F +L+ + P L F++ L AP+ + +D D Sbjct: 737 DI--------IDEFQNYALSAERAGLPGLQAFLETLEAA-------APEIKRELDQGRDE 781 Query: 830 VRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDQDAPTHFSAF----GRRSE 885 VRI+TVH+AKGLE VV ++D + L + D P F + Sbjct: 782 VRIMTVHAAKGLEGAVVFLVDPGSAVWTGSRAPKLIPYDFQGDGPP-VKGFLWQPNSSCQ 840 Query: 886 RGSAREELFEQEDQLRTQEDW-NLLYVAVTRAKQLLLVSGVAGKRGTGEG---------- 934 G E+ + ++ R +E++ LLYV +TRA+ L++ G G R +GE Sbjct: 841 TGFTAAEIEKLKN--RAEEEYRRLLYVGMTRAEDRLIICGYRGTRESGETWHRLVEDALA 898 Query: 935 -------GVVEGSWYQRLFASDAPVREIGEEAVQGA-DVAAVEEVFSLSL-FDPR-PQPM 984 V G +R + EI EE GA + + + + +P P+P+ Sbjct: 899 AKSETFVHPVTGVAARRYRKTPRSFIEINEEDQAGATSLPPLPHDYRQPMKAEPGLPRPL 958 Query: 985 LLFGA-ADGEQEQTPP-----AIADDGTLVSNEAIDEGVALHALLERLTHANAWPLTLPA 1038 GA A E ++ PP + GT A+ G A+H LL+ L A Sbjct: 959 APSGASALIEADEEPPLDLSSPVLQPGTGAPAFALRRGTAIHMLLQYLPDVAPEKREHLA 1018 Query: 1039 PPTLVR----WLGVSAEMA-QVVHAQARVVLAQPQLERFFNPALHRWARNEMEIVTPAGV 1093 L R W A Q VHA +L P+ F P +R E+ ++ + Sbjct: 1019 ADYLARIAADWPDAERLKAWQSVHA----ILDDPR----FGPVFAEGSRGEVAVMGMIDI 1070 Query: 1094 --------LRLDRVVMFEEEVWVLDYKR-----RLLDSERAEYAAQLARYRSALVSVFSD 1140 ++DR+ + E V ++DYK + L++ + Y AQLA YR L ++ Sbjct: 1071 GGRDHAVSGQIDRISVDESRVLIVDYKTNRPPPKTLEAVPSAYRAQLALYRELLRPLYPG 1130 Query: 1141 KRIRSALITADG 1152 + + +AL+ +G Sbjct: 1131 RVVEAALLFTEG 1142 >AGc39 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1233 Score = 224 bits (572), Expect = 8e-58, Method: Compositional matrix adjust. Identities = 266/947 (28%), Positives = 416/947 (43%), Gaps = 107/947 (11%) Query: 25 REACDPRHSVVVEACAGSGKTWLLVARMLRLLLSGAQAPELLAITFTRKAAQEMRERLLE 84 R A DP S V A AGSGKT +L R++RLLL+G + +L +T+T+ AA EM R+ + Sbjct: 75 RLASDPASSAWVSANAGSGKTHVLTQRVIRLLLAGCRPSAILCLTYTKAAASEMSSRVFD 134 Query: 85 LLHELALADEHHAASLLRER-GVAEADLPRLLPL--ARGLYERILSSEQSLSIDTFHSWF 141 L E A + S L++R E +P + L AR L+ + L + L I T H++ Sbjct: 135 RLAEWATLPD----SDLKDRITTIEGKVPDRIKLAEARRLFAKALETPGGLKIQTIHAFC 190 Query: 142 ARLL-QIALLASGVPHGYTLTEKNG-ELLEEAYRRFMQTLREPEGAIVKAALLELYELVG 199 LL Q L A+ H L ++ LL EA R + + + A + AL + +L Sbjct: 191 EALLHQFPLEANVAGHFSVLDDRAATTLLAEARRSLLTAVSTEDDAELVQALAYVLDLAD 250 Query: 200 DFNTRQLLDAFIDKRAEWWA----ATQDDGEEAEPSPLRWLEALCGDDARRDARLALWDD 255 + LL A I R+ + A Q G + LR + + A A W Sbjct: 251 ESGLEALLSAIIANRSALRSFLHEAKQSGGLDVR---LRQEMQIAAGETEETAAEAFWPL 307 Query: 256 APLVARASQVAVLLGQ--GGSLNKNRAVAIESALTAGPALEHFDALYSQFFDDKDKPRKN 313 L + L GGS A A+ A + + + + K + + + Sbjct: 308 PGLSGLVLDTYLTLADEVGGSRVIEVAYALREAKRQPDPVRRMELIEAALLTAKGEKKSD 367 Query: 314 GKVKSLLAALTQHFAASDEAALAAFEDEFNAIGEALRKLQGRSKEKLVLQLNRALFAAGR 373 V + Q A AL D A R + ++++ AL A R Sbjct: 368 AYV---INKGMQKSAPDLVDALTLARDHVVACRNRYRLV------RMLVATKSALVLAER 418 Query: 374 AYLDCYQEVKSEQRVLDFADLEWQAYRLLKDDASAAYLQTRLDARYKHILLDEFQDTNPL 433 D ++++K ++ LDF DL +A LL D + A++ +LD HIL+DE QDT+P+ Sbjct: 419 LIGD-FEDLKKQRSQLDFEDLIERAANLLNRDTAGAWVHYKLDQGIDHILVDEAQDTSPV 477 Query: 434 QWCIVRCW-LDAYGGDAAQP---SVFVVGDPKQSIYRFRRAEPRVFVAARELLRSQGAAI 489 QW I++ D + G++A+ ++F VGD KQSIY F+ A P F R Sbjct: 478 QWSIIQSLAADFFNGESARMGRRTLFAVGDEKQSIYSFQGARPERFSQER---------- 527 Query: 490 LRANQTRRNASAVVNVLNRSFIRGGNPLFAQQTTLGLAG-GEVWRLPLVRQEEGEENVTR 548 ++T+R V+ + ++F R PL + T LA +V+ P +N + Sbjct: 528 ---DETKRR----VDQVEQAFHRIRLPLSFRSTEDVLAAVDQVFSDP--------KNASG 572 Query: 549 PETDAESASAAASSAASEGEQDIIAWRNPLTTPRGEE---------EDARRLLEGQALAQ 599 D E ++ A G ++ P TT E+ E A + + +A Sbjct: 573 LSADNEPVEHRSNRAGHPGTVEVWDMVAPETTEDEEDWTAPFDALRESAPATIVARRIAA 632 Query: 600 ALLKAYREVPVITGKSERAMRWGDIMLLVRKRTHLAAYESAL-----RAAGIPFISDKRG 654 + +I ERA+ GDI++LVRKR AA+ +AL R IP R Sbjct: 633 RIADMIGNQTIIEKGVERAVEPGDILVLVRKR---AAFVNALTRELKRRKNIPVAGADRL 689 Query: 655 GLLESLEIADLIALLTFLITPNDTRALAHVLKSPIIGAADDDLVQIARRAAHAEGGHWWQ 714 L + + + DL+AL F++ P D +LA +LKSP+ +DD+ +IA A +E WQ Sbjct: 690 RLTDHIAVQDLLALGRFVVLPEDDLSLAALLKSPLFNLTEDDVFEIA--ATRSEAESVWQ 747 Query: 715 HLQAMQQEGAASAALVRAVTLLQRWLQAAPHLPVHDLLDRI--LHQG--ELVARYAQNAS 770 LQ + E + ++V L+ ++ + VHD + LH G + + R AS Sbjct: 748 RLQVLSGEETSRLSIV--TDKLRHFISLSKTATVHDFFAAVLTLHDGRKKFLGRLGNEAS 805 Query: 771 PLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRTSGGDAPD-EASVDASADA 829 + + F+ +L+ + P L F+ L D+P+ + D Sbjct: 806 DV--------LDEFLSFALDHERTGLPGLQAFLSVLET-------DSPEVKREQDKDRGE 850 Query: 830 VRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDQDA-PTHFSAFGRRSERGS 888 VRI+TVH++KGLEAPVV ++D ++ L D DA P G + Sbjct: 851 VRIMTVHASKGLEAPVVFVVDGGSKAFNHSHVPKLRFVEGDGDAFPVWLPGSGFSNHLIR 910 Query: 889 AREELFEQ--EDQLRTQEDWNLLYVAVTRAKQLLLVSGVAGKRGTGE 933 + EE + ED+ R LLYVA+TRA L+V G G++ E Sbjct: 911 SDEERLKTAAEDEYR-----RLLYVAMTRAADHLVVCGYRGQKENPE 952 >SMc02760 [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Sme Sinorhizobium meliloti Length = 1189 Score = 213 bits (541), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 337/1234 (27%), Positives = 498/1234 (40%), Gaps = 200/1234 (16%) Query: 27 ACDPRHSVVVEACAGSGKTWLLVARMLRLLLSGAQAPELLAITFTRKAAQEMRERLLELL 86 A DP S V A AGSGKT +L R++RLLL+G + +L +T+T+ AA EM R+ E L Sbjct: 27 ASDPACSAWVSANAGSGKTHVLTQRVIRLLLAGCRPSAILCLTYTKAAASEMSNRVFEKL 86 Query: 87 HELALADEHHAASLLRERGVAEADLPRLLPL--ARGLYERILSSEQSLSIDTFHSWFARL 144 E A D+ +L + E P + AR L+ R L + L I T H++ L Sbjct: 87 AEWATLDD---TTLEKRIEAIEGKRPPTAKIQEARRLFARALETPGGLKIQTIHAFCEAL 143 Query: 145 L-QIALLASGVPHGYTLTEKNGELL--EEAYRRFMQTLREPEGAIVKAALLELYELVGDF 201 L Q L A+ H L ++ +L + T +G + + A + +L D Sbjct: 144 LHQFPLEANVAGHFSVLDDRAAAVLLADARRALLTATAAASDGELAE-AFATVLDLADDT 202 Query: 202 NTRQLLDAFIDKRAEWWA----ATQDDGEEAEPSPLRWLEALCGDDARRDARLALWDDAP 257 +LL A + RA A A+ G EA LR L + A+W A Sbjct: 203 GLEKLLAAIVANRAPIQAFLDHASGRGGMEAH---LRAALGLEPGETAGTVMAAVWPLAG 259 Query: 258 LVARASQVAVLLGQGGSLNKNRAVAIESALTAGPALEHFDALYSQ----FFDDKDKPRKN 313 L A + LG L + AI L A A++ YS+ FF+ KP+ Sbjct: 260 LNGPALDDYIDLGL--RLGGAKPSAIADGLRAVRAIDDAATRYSKLVELFFNGGGKPKAE 317 Query: 314 GKVKSLLAALTQHFAASDEAALAAFEDEFNAIGEALRKLQ--GRSKEKLVL--QLNRALF 369 + L A + A E + A + L +Q G ++ LVL +LNR Sbjct: 318 ---SAFLNAAMRRAAPQLELRVEEARSHMLACVDRLSIVQMYGATRAALVLAERLNRD-- 372 Query: 370 AAGRAYLDCYQEVKSEQRVLDFADLEWQAYRLLKDDASAAYLQTRLDARYKHILLDEFQD 429 Y+ +K + LDF DL + LL A++ +LD HIL+DE QD Sbjct: 373 ---------YEALKKARSQLDFEDLIHRTAALLARSDVGAWVHYKLDQGIDHILVDEAQD 423 Query: 430 TNPLQWCIVRCW-LDAYGGDAAQP---SVFVVGDPKQSIYRFRRAEPRVFVAARELLR-- 483 T+P QW I++ D + G+ A+ ++F VGD KQSIY F+ A P F L Sbjct: 424 TSPAQWTIIQSLAADFFAGETARADDRTIFAVGDEKQSIYSFQGARPERFSRESTLTERR 483 Query: 484 ----SQGAAILRANQTRRNASAVVNVLNRSFIRGGN---------PLFAQQTTLGLAGG- 529 ++ + +R + R+ V++ ++ F GN + +G G Sbjct: 484 VRAGNKHFSPIRLQLSFRSTVDVLSAVDTVFANPGNARGLSARSEAIVHASNRIGQPGAV 543 Query: 530 EVWRLPLVRQEEGEENVTRPETDAESASAAASSAASEGEQDIIAWRNPL-TTPRGEEEDA 588 ++W +V PE AASE + W P TP E A Sbjct: 544 DLW------------DVIAPE-----------PAASEED-----WTAPFDATP----ERA 571 Query: 589 RRLLEGQALAQALLKAYREVPVITGKSERAMRWGDIMLLVRKR-THLAAYESALRAAG-I 646 + + +A L VI RAMR GD+++LVRKR + A AL+ G I Sbjct: 572 PVNILARRIAAVLEDWIGRETVIEKGVRRAMRPGDVIVLVRKRDAFVNALTRALKRRGNI 631 Query: 647 PFISDKRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIIGAADDDLVQIARRAAH 706 P R L + + DLIAL F++ P D +LA +LKSP++ ++D+ ++A R Sbjct: 632 PVAGADRLVLTSHIAVQDLIALGRFVLLPEDDLSLAALLKSPLLDLGEEDVFELAAR--R 689 Query: 707 AEGGHWWQHLQAMQQEGAASAALVR-AVTLLQRWLQAAPHLPVHDLLDRIL----HQGEL 761 EG W+ L +Q GA + AV L R+ A L HD R+L + Sbjct: 690 TEGESLWRRL---RQAGAEETSRYHEAVRTLSRYSGLARELLPHDFYARVLGADGGRRAF 746 Query: 762 VARYAQNASPLTRSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRTSGGDAPD-E 820 +AR S + + F+ +L+ + P L FI L + +AP + Sbjct: 747 LARLGSEVSDI--------LDEFLTFALDHERNGLPGLQAFISTLEI-------EAPTVK 791 Query: 821 ASVDASADAVRILTVHSAKGLEAPVVAILDANHSDSVEDNLGILCAWPQDQDAPTHFSAF 880 D D VR++TVH+AKGLEAPVV ++D V + L + Q + + Sbjct: 792 REQDKERDEVRVMTVHAAKGLEAPVVFLVDGGGEAFVRQQVSDLRFLEKAQVDHSTLTVP 851 Query: 881 GRRSERGSAREELF----EQEDQLRTQEDWNLLYVAVTRAKQLLLVSGVAGKRGTGEG-- 934 R+ GSA L E+ +L +E LLYV +TRA L+V G G+R + Sbjct: 852 VWRAP-GSAPNSLIAADNERLKKLAEEEYRRLLYVGMTRAADRLIVCGYRGQRQNTDTWH 910 Query: 935 GVVEGSWYQRLFASDAP-VREIGEEAVQGA---------DVAAVE----------EVFSL 974 +V+G+ Q L P + G E QG D+ E Sbjct: 911 SMVQGTLAQDLKGRGTPRLFRAGSEEWQGIAWREAHVPRDLPTSEGRSEESQRPTAGLPT 970 Query: 975 SLFDPR------PQPMLLFGAADGEQEQTPPAIADDGTLVSNEA----IDEGVALHALL- 1023 +LF P P+P+ G + AI A + G LH LL Sbjct: 971 ALFTPPAAPRRLPRPLAPSGTTIAIDDPDAEAIVGSALFAGKSAPKFSMLRGAILHRLLQ 1030 Query: 1024 --------ERLTHANAW-PLTLPAPPTLVRWLGVSAEMAQVVHAQARVVLAQPQLERFFN 1074 ERL A + ++P P R M + HA Sbjct: 1031 VLPSVDGPERLAAAERYLARSVPRWPEAERRALAGTVMDVLDHAD-------------LQ 1077 Query: 1075 PALHRWARNEMEIVTPAGVLRL-----------DRVVMFEEEVWVLDYKRRLLDSERAE- 1122 P +R E+ ++ G L+L DR+ + + V + DYK E E Sbjct: 1078 PLFGEHSRAEVSVM---GTLKLGVREFAVSGRIDRLAVTGDMVTIADYKTNREIPETPEE 1134 Query: 1123 ----YAAQLARYRSALVSVFSDKRIRSALITADG 1152 Y QLA YR L ++ KR R LI +G Sbjct: 1135 IAPVYRNQLAIYRELLKPLYPGKRFRCVLIFTEG 1168 >BS_addA [L] COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) Bsu Bacillus subtilis Length = 1232 Score = 167 bits (422), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 241/949 (25%), Positives = 396/949 (41%), Gaps = 146/949 (15%) Query: 32 HSVVVEACAGSGKTWLLVARMLRLLLSGAQAP----ELLAITFTRKAAQEMRERLLELLH 87 ++V A AGSGKT +LV RM+R + + + P LL +TFT +A EM+ R+ E L Sbjct: 24 QDILVAAAAGSGKTAVLVERMIRKI-TAEENPIDVDRLLVVTFTNASAAEMKHRIAEALE 82 Query: 88 ELALADEHHAASLLRERGVAEADLPRLLPLARGLYERILSSEQSLSIDTFHSWFARLLQI 147 + L++ G R LS SI T HS+ ++L+ Sbjct: 83 K----------ELVQRPGSLHI-------------RRQLSLLNRASISTLHSFCLQVLKK 119 Query: 148 ALLASGVPHGYTLTEKN-GELLEEAYRRFMQTLREPEGAIVKAALLELYELVGDFNT-RQ 205 + G+ + ++ GEL+ + + L E E A + A +ELV + T R Sbjct: 120 YYYLIDLDPGFRIADQTEGELIGD---EVLDELFEDEYAKGEKAF---FELVDRYTTDRH 173 Query: 206 LLD-AFIDKRAEWWAATQDDGEEAEPSPLRWLEALCG--DDARRDARLALWDDAPLVARA 262 LD F+ K+ ++ + P+P WLE+ D + + A ++ P Sbjct: 174 DLDLQFLVKQVYEYSRSH-------PNPEAWLESFVHLYDVSEKSA----IEELPFYQYV 222 Query: 263 SQVAVLLGQGGSLNKNRAVAIESALTAGPA---------LEHFDALYSQFFDDKDKPRKN 313 + ++ G RA+ + A GPA L D L Q DD + K Sbjct: 223 KEDIAMVLNGAKEKLLRALELTKA-PGGPAPRADNFLDDLAQIDELI-QHQDDFSELYKR 280 Query: 314 GKVKSLLAALTQHFAASDEAALAAFEDEFNAIGEALRKLQG----RSKEKLVLQLNR--- 366 S A D A L D N + L KL+ RS E+ + L Sbjct: 281 VPAVSFKRAKAVKGDEFDPALLDEATDLRNGAKKLLEKLKTDYFTRSPEQHLKSLAEMKP 340 Query: 367 ---ALFAAGRAYLDCYQEVKSEQRVLDFADLEWQAYRLLKDDASAAYLQTRLDARY---- 419 L +Y ++ K E+ ++DF+DLE +L + + AR+ Sbjct: 341 VIETLVQLVISYGKRFEAAKQEKSIIDFSDLEHYCLAILTAENDKGEREPSEAARFYQEQ 400 Query: 420 -KHILLDEFQDTNPLQWCIVRCWLDAYGGDAAQPSVFVVGDPKQSIYRFRRAEPRVFVAA 478 +L+DE+QDTN +Q I++ G ++F+VGD KQSIYRFR AEP +F++ Sbjct: 401 FHEVLVDEYQDTNLVQESILQL---VTSGPEETGNLFMVGDVKQSIYRFRLAEPLLFLSK 457 Query: 479 RELLRSQGAAILRANQTRRNASAVVNVLNRSFIRGGNPLFAQQTTLGLAGGEVWRLPLVR 538 + G R +N + ++L+ + N LF Q L GG++ + Sbjct: 458 YKRFTESGEGTGRKIDLNKNFRSRADILDST-----NFLFKQ-----LMGGKIGEVDYDE 507 Query: 539 QEEGEENVTRPETDAESASAAASSAASEGEQDIIAWRNPLTTPRGEEEDARRLLEGQALA 598 Q E + P+ D E E +++ N T EE A L Q A Sbjct: 508 QAELKLGAAYPDND-------------ETETELLLIDNAEDTDASEE--AEELETVQFEA 552 Query: 599 QALLKAYREV-----PVITGK--SERAMRWGDIMLLVRKRTHLAAYESALRAAGIPFISD 651 +A+ K R++ V GK + R +++ DI++L+R LRA GIP ++ Sbjct: 553 KAIAKEIRKLISSPFKVYDGKKKTHRNIQYRDIVILLRSMPWAPQIMEELRAQGIPVYAN 612 Query: 652 KRGGLLESLEIADLIALLTFLITPNDTRALAHVLKSPIIGAADDDLVQIARRAAHAEGGH 711 G E++E+A +++L + P LA VL+SPI+GA +++L I A Sbjct: 613 LTSGYFEAVEVAVALSVLKVIDNPYQDIPLASVLRSPIVGADENELSLIRLENKKAP--- 669 Query: 712 WWQHLQAMQQEGAASAALVRAVTL----LQRWLQAAPHLPVHDLLDRILHQGELVARYAQ 767 +++ ++ G S L + + LQ+W + + V +L+ + +Y Sbjct: 670 YYEAMKDYLAAGDRSDELYQKLNTFYGHLQKWRAFSKNHSVSELIWEVYRD----TKYMD 725 Query: 768 NASPLT-RSQTLGNIAAFVELSLNMDAGRYPSLPKFIDALRVLQRTS--GGDAPDEASVD 824 + Q N+ + + ++ + L +F LR ++R G D + Sbjct: 726 YVGGMPGGKQRQANLRVLYDRARQYESTAFRGLFRF---LRFIERMQERGDDLGTARGLS 782 Query: 825 ASADAVRILTVHSAKGLEAPVVAI---------LDANHSDSVEDNLGILCAWPQDQDAPT 875 D VR++T+HS+KGLE PVV + +D N S ++ LG + Q Sbjct: 783 EQEDVVRLMTIHSSKGLEFPVVFVAGLGRNFNMMDLNKSYLLDKELGFGTKYIHPQ-LRI 841 Query: 876 HFSAFGRRSERGSAREELFEQEDQLRTQEDWNLLYVAVTRAKQLLLVSG 924 + + + R EL +E LR +LYVA+TRAK+ L + G Sbjct: 842 SYPTLPLIAMKKKMRRELLSEE--LR------VLYVALTRAKEKLFLIG 882