BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0708.p (426 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PM0273 [G] COG1593 TRAP-type C4-dicarboxylate transport system, ... 460 e-129 PA5169 [G] COG1593 TRAP-type C4-dicarboxylate transport system, ... 451 e-126 PA0886 [G] COG1593 TRAP-type C4-dicarboxylate transport system, ... 413 e-115 VC1927 [G] COG1593 TRAP-type C4-dicarboxylate transport system, ... 409 e-114 BH2671 [G] COG1593 TRAP-type C4-dicarboxylate transport system, ... 321 2e-87 >PM0273 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component Pmu Pasteurella multocida Length = 427 Score = 460 bits (1183), Expect = e-129, Method: Compositional matrix adjust. Identities = 226/406 (55%), Positives = 313/406 (77%) Query: 17 GMPISISLGLTVLTFLFTMTDVPIQSVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVAR 76 G+PI+ISLGL+ + + + S+A+KLF E + ++AIPFF+LAG F+T GGVA+ Sbjct: 17 GVPIAISLGLSGAIVIMLFSQDSLSSLAIKLFETSEHYTLLAIPFFLLAGAFMTTGGVAK 76 Query: 77 RMINFATSMVGHWYGGLALAGVLACALFAAVSGSSPATVVAIGSIILPAMVKQGFPNRFG 136 R+I+FA + VGH GGLA+A V++C LFAA+SGSSPATV A+GSI + MV+ G+P FG Sbjct: 77 RLIDFANATVGHIRGGLAIASVMSCMLFAALSGSSPATVAAVGSIAIAGMVRSGYPIGFG 136 Query: 137 AGVITTSGALGILIPPSIVMVMYSVSTNTSVGKLFMAGVVPGLLLAFLLGLTTWYLARKN 196 G+I +G LGILIPPS+VMV+Y+ +T TSVGKLFMAGVVPGLLL L + + +AR Sbjct: 137 TGIICNAGTLGILIPPSVVMVVYAAATETSVGKLFMAGVVPGLLLGVALMVAIYIVARIK 196 Query: 197 NYPRLRKATWAERFAAFRKSGWGLFLIVIVMGGIYTGVFTPTEAAAMAAVYAFFISVFVY 256 N P +A+ E F A RK+ WGL L+VI++GGIY+G+FTPTEAAA+AAVY+F ++VF+Y Sbjct: 197 NLPAQPRASVKEWFRAARKAIWGLLLMVIILGGIYSGIFTPTEAAAVAAVYSFVVAVFIY 256 Query: 257 KDLRLSQVPKVLLDSASMSAMLLYIITNAVLFSFLVTSENIPQAMAAWITDSGLGPITFL 316 KD++LS+ P+VLL+S +S ML++II NA+LF+ ++T+E IPQ + +T L P FL Sbjct: 257 KDIKLSECPRVLLESGKLSVMLMFIIANAMLFAHVLTTEQIPQLITETVTKMELSPWMFL 316 Query: 317 LVVNILLLLAGNVMEPSSIVLILAPILFPVAMKLGIDPVHFGILIVVNMEVGMCHPPVGL 376 +VVNI+LL+AG MEPS+I+LILAPILFP+A++LGIDP+H G+++VVNME+GM PP+GL Sbjct: 317 IVVNIVLLIAGAFMEPSAIILILAPILFPIAVQLGIDPIHLGVIMVVNMEIGMITPPIGL 376 Query: 377 NLYVASGITKMGITELTIAVMPWLLTMLGFLMLVTYWPTLSLWLPN 422 NL+VAS ++KM +T + A PWL+ +L FL+ +TY P +S+ LPN Sbjct: 377 NLFVASAVSKMPLTAVIRAATPWLMLLLAFLIAITYIPAISMALPN 422 >PA5169 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component Pae Pseudomonas aeruginosa Length = 427 Score = 451 bits (1159), Expect = e-126, Method: Compositional matrix adjust. Identities = 235/410 (57%), Positives = 321/410 (78%), Gaps = 2/410 (0%) Query: 14 MLTGMPISISLGLT-VLTFLFTMTDVPIQSVALKLFTGIEKFEIMAIPFFILAGNFLTHG 72 M G+PI++SLGL+ LT L D ++S+A+KLF E + ++AIPFF+L+G F+T G Sbjct: 14 MFIGVPIAVSLGLSGALTILLFSPD-SVRSLAIKLFETSEHYTLLAIPFFLLSGAFMTTG 72 Query: 73 GVARRMINFATSMVGHWYGGLALAGVLACALFAAVSGSSPATVVAIGSIILPAMVKQGFP 132 GVARR+I+FA + VGH GGLA+A VLAC LFAA+SGSSPATV A+GSI + MV+ G+P Sbjct: 73 GVARRLIDFANACVGHIRGGLAIAAVLACMLFAALSGSSPATVAAVGSIAIAGMVRSGYP 132 Query: 133 NRFGAGVITTSGALGILIPPSIVMVMYSVSTNTSVGKLFMAGVVPGLLLAFLLGLTTWYL 192 FGAG++ +G LGILIPPSIVMV+Y+ +T TSVGKLF+AGVVPGLLL +L + + + Sbjct: 133 QAFGAGIVCNAGTLGILIPPSIVMVVYAAATETSVGKLFIAGVVPGLLLGLILMVVIYIV 192 Query: 193 ARKNNYPRLRKATWAERFAAFRKSGWGLFLIVIVMGGIYTGVFTPTEAAAMAAVYAFFIS 252 AR P + + + E A+ RK+ WGL L+VI++GGIY+G FTPTEAAA+AAVY+ F++ Sbjct: 193 ARVKKLPAMPRVSLREWLASARKALWGLLLMVIILGGIYSGAFTPTEAAAVAAVYSAFVA 252 Query: 253 VFVYKDLRLSQVPKVLLDSASMSAMLLYIITNAVLFSFLVTSENIPQAMAAWITDSGLGP 312 +FVY+D+RLS+ PKVLL+S ++ ML++II NA+LF+ ++T+E IPQ++A+W+T+ GL P Sbjct: 253 LFVYRDMRLSECPKVLLESGKLTIMLMFIIANAMLFAHVLTTEQIPQSIASWVTELGLSP 312 Query: 313 ITFLLVVNILLLLAGNVMEPSSIVLILAPILFPVAMKLGIDPVHFGILIVVNMEVGMCHP 372 FLLVVNI+LL+AGN MEPS+I+LILAPI FP+AM+LGIDP+H GI++VVNME+G+ P Sbjct: 313 WMFLLVVNIVLLIAGNFMEPSAIILILAPIFFPIAMELGIDPIHLGIIMVVNMEIGLITP 372 Query: 373 PVGLNLYVASGITKMGITELTIAVMPWLLTMLGFLMLVTYWPTLSLWLPN 422 PVGLNL+V S +T M + A +PWL+ +L FL++VTY P +SL LPN Sbjct: 373 PVGLNLFVTSAVTGMPLGATIRAALPWLMILLVFLIIVTYIPAVSLALPN 422 >PA0886 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component Pae Pseudomonas aeruginosa Length = 427 Score = 413 bits (1062), Expect = e-115, Method: Compositional matrix adjust. Identities = 240/409 (58%), Positives = 320/409 (78%), Gaps = 2/409 (0%) Query: 17 GMPISISLGLT-VLTFLFTMTDVPIQSVALKLFTGIEKFEIMAIPFFILAGNFLTHGGVA 75 G+PI+ISLGL+ LT L D ++S+A+KLF E + ++AIPFF+L+G F+T GGVA Sbjct: 17 GVPIAISLGLSGALTILLFSPD-SVRSLAIKLFETSEAYTLLAIPFFLLSGAFMTTGGVA 75 Query: 76 RRMINFATSMVGHWYGGLALAGVLACALFAAVSGSSPATVVAIGSIILPAMVKQGFPNRF 135 RR+I+FA + VGH GGLA+A VLAC LFAA+SGSSPATV A+GSI + MV+ G+P F Sbjct: 76 RRLIDFANACVGHIRGGLAIAAVLACMLFAALSGSSPATVAAVGSIAVAGMVRSGYPRAF 135 Query: 136 GAGVITTSGALGILIPPSIVMVMYSVSTNTSVGKLFMAGVVPGLLLAFLLGLTTWYLARK 195 GAG+I +G LGILIPPSIVMV+Y+ +T TSVGKLF+AGVVPGLLL +L + + +AR Sbjct: 136 GAGIICNAGTLGILIPPSIVMVVYAAATETSVGKLFVAGVVPGLLLGVILMVVIYIVARV 195 Query: 196 NNYPRLRKATWAERFAAFRKSGWGLFLIVIVMGGIYTGVFTPTEAAAMAAVYAFFISVFV 255 P +A++ E AA R++GWGL L+VI++GGIY+G+FTPTEAAA+AAVY+ F+++FV Sbjct: 196 KKLPAQPRASFREWLAAARRAGWGLLLLVIILGGIYSGLFTPTEAAAVAAVYSAFVALFV 255 Query: 256 YKDLRLSQVPKVLLDSASMSAMLLYIITNAVLFSFLVTSENIPQAMAAWITDSGLGPITF 315 YKD+RL PKVLL+S +S ML++II NA+LF+ ++T+E IPQ + W+ GL PI F Sbjct: 256 YKDMRLRDCPKVLLESGRLSIMLMFIIANAMLFAHVLTTEQIPQQITEWVVQEGLTPIGF 315 Query: 316 LLVVNILLLLAGNVMEPSSIVLILAPILFPVAMKLGIDPVHFGILIVVNMEVGMCHPPVG 375 LL+VN++LL+AG+ MEPS+IVLILAPI FP+AMKLGIDP+H GI++VVNME+G+ HPPVG Sbjct: 316 LLMVNVVLLVAGSFMEPSAIVLILAPIFFPIAMKLGIDPIHLGIVMVVNMEIGLVHPPVG 375 Query: 376 LNLYVASGITKMGITELTIAVMPWLLTMLGFLMLVTYWPTLSLWLPNLI 424 LNL+V S +T M + A +PWL+ +L FL+LVTY P +SLWLP L+ Sbjct: 376 LNLFVTSAVTGMPLGATIRAALPWLMILLLFLILVTYVPLISLWLPGLL 424 >VC1927 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component Vch Vibrio cholerae Length = 453 Score = 409 bits (1051), Expect = e-114, Method: Compositional matrix adjust. Identities = 220/445 (49%), Positives = 311/445 (69%), Gaps = 21/445 (4%) Query: 1 MNALIIFVLLFGLMLTGMPISISLGLTVLTFLFTMTDVPIQSVALKLFTGIE-KFEIMAI 59 M ++F+L+ G+M+ G+PI+ISLGL+ + FL +D + SVA LF + ++AI Sbjct: 1 MAVALLFILVIGMMIVGVPIAISLGLSSILFLLWHSDASLASVAQTLFNAFAGHYTLLAI 60 Query: 60 PFFILAGNFLTHGGVARRMINFATSMVGHWYGGLALAGVLACALFAAVSGSSPATVVAIG 119 PFFILA F++ GGVA+R+I FA +MVG + GGLA+A V+AC +FAA+SGSSPATVVAIG Sbjct: 61 PFFILASTFMSTGGVAKRIIRFAIAMVGWFRGGLAIASVVACMMFAALSGSSPATVVAIG 120 Query: 120 SIILPAMVKQGFPNRFGAGVITTSGALGILIPPSIVMVMYSVSTNTSVGKLFMAGVVPGL 179 SI++ MVK G+ F AGVI +G LGILIPPSIVMV+YS +TN SVG++F+ GVVPGL Sbjct: 121 SIVIAGMVKNGYSKEFAAGVICNAGTLGILIPPSIVMVVYSAATNVSVGRMFLGGVVPGL 180 Query: 180 LLAFLLGLTTWYLARKNNYPRLRKATWAERFAAFRKSGWGLFLIVIVMGGIYTGVFTPTE 239 L +L + + AR N P+ W E A +++ WGL L+VI++GGIY G+FTPTE Sbjct: 181 LAGLMLIIAIYITARIKNLPKQPFVGWKEALKAAKEASWGLLLVVIILGGIYGGIFTPTE 240 Query: 240 AAAMAAVYAFFISVFVYKDL-----RLSQVP---------------KVLLDSASMSAMLL 279 AAA+AAVY+FFI+ F+Y+D+ + + P L D+ ++ ML+ Sbjct: 241 AAAVAAVYSFFIANFIYRDMGPFADKTNTKPVLVKVVETFVHKDTKATLYDAGKLTIMLM 300 Query: 280 YIITNAVLFSFLVTSENIPQAMAAWITDSGLGPITFLLVVNILLLLAGNVMEPSSIVLIL 339 +II NA++ ++T E IPQ + + +GLGPITFL+VVN++LL+ G MEPS +++I+ Sbjct: 301 FIIANALILKHVLTEERIPQMITESMLSAGLGPITFLIVVNLILLVGGQFMEPSGLLVIV 360 Query: 340 APILFPVAMKLGIDPVHFGILIVVNMEVGMCHPPVGLNLYVASGITKMGITELTIAVMPW 399 AP++FP+A+ LGIDP+H GI++VVNME+GM PPVGLNL+V SG+ KM + + A +PW Sbjct: 361 APLVFPIAIALGIDPIHLGIMMVVNMEIGMITPPVGLNLFVTSGVAKMSMMNVVKAALPW 420 Query: 400 LLTMLGFLMLVTYWPTLSLWLPNLI 424 + M FL++VTY P +S WLP L+ Sbjct: 421 VGVMFLFLIIVTYVPWVSTWLPTLL 445 >BH2671 [G] COG1593 TRAP-type C4-dicarboxylate transport system, large permease component Bha Bacillus halodurans Length = 426 Score = 321 bits (823), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 175/424 (41%), Positives = 271/424 (63%), Gaps = 1/424 (0%) Query: 1 MNALIIFVLLFGLMLTGMPISISLGLTVLTFLFTMTDVPIQSVALKLFTGIEKFEIMAIP 60 M A ++F L+L +PI I+LGL L + +P++ +A L T ++ F +MA+P Sbjct: 1 MTAAVLFGSFALLLLLSVPIGIALGLATLLAILYSGTIPLEFLAQGLITSVDSFPLMAVP 60 Query: 61 FFILAGNFLTHGGVARRMINFATSMVGHWYGGLALAGVLACALFAAVSGSSPATVVAIGS 120 FFILAG + GGV R+ N A ++VG+ GG A+A V+ C FAA+SGS PATV AIG Sbjct: 61 FFILAGEIMARGGVTDRLFNVANALVGNRTGGFAIATVITCMFFAAISGSGPATVAAIGG 120 Query: 121 IILPAMVKQGFPNRFGAGVITTSGALGILIPPSIVMVMYSVSTNTSVGKLFMAGVVPGLL 180 I++PAMVK G+ RF ++ +G+LG++IPPSI MV+Y VS + S+G LF+ G++PGL+ Sbjct: 121 IMIPAMVKHGYDKRFATALVAAAGSLGVIIPPSIPMVIYGVSASASIGGLFVGGIIPGLM 180 Query: 181 LAFLLGLTTWYLARKNNYP-RLRKATWAERFAAFRKSGWGLFLIVIVMGGIYTGVFTPTE 239 +A L +Y +RK Y K ++ + ++ W L + I++GGIY GVFTPTE Sbjct: 181 IAGALMAYAYYYSRKKGYKGSTEKTSFKHILQSVWEAKWALVIPFIILGGIYGGVFTPTE 240 Query: 240 AAAMAAVYAFFISVFVYKDLRLSQVPKVLLDSASMSAMLLYIITNAVLFSFLVTSENIPQ 299 AA +A VY+ +Y++L + Q+P+V D+A +A +L I+ +A F L+T E IP Sbjct: 241 AAVVAVVYSLLAGFILYRELTIKQLPRVFADAALTTATILIIVGSATAFGRLLTIEQIPN 300 Query: 300 AMAAWITDSGLGPITFLLVVNILLLLAGNVMEPSSIVLILAPILFPVAMKLGIDPVHFGI 359 +A W+ I +L++ ILLL+ G M+ + ++IL PIL P+A+ LG DP+HFG+ Sbjct: 301 QVADWMLTISENKIILILLITILLLVVGCFMDTLAAIIILTPILLPIAVTLGYDPIHFGM 360 Query: 360 LIVVNMEVGMCHPPVGLNLYVASGITKMGITELTIAVMPWLLTMLGFLMLVTYWPTLSLW 419 ++VVN+ +G PP+G+NL+V SGI+ + I L+ A++P+ L M+ L ++ + P L+L+ Sbjct: 361 IMVVNLAIGFITPPLGVNLFVGSGISGISIESLSKAIVPFFLVMVLTLFILVFVPQLTLY 420 Query: 420 LPNL 423 L L Sbjct: 421 LVEL 424