BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0001.0670.p (260 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0518 [J] COG0030 Dimethyladenosine transferase (rRNA methylat... 287 1e-77 NMA0902 [J] COG0030 Dimethyladenosine transferase (rRNA methylat... 273 3e-73 NMB0697 [J] COG0030 Dimethyladenosine transferase (rRNA methylat... 273 3e-73 PA0592 [J] COG0030 Dimethyladenosine transferase (rRNA methylati... 263 4e-70 ksgA [J] COG0030 Dimethyladenosine transferase (rRNA methylation... 260 3e-69 >RSc0518 [J] COG0030 Dimethyladenosine transferase (rRNA methylation) Rso Ralstonia solanacearum Length = 281 Score = 287 bits (735), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 156/259 (60%), Positives = 185/259 (71%), Gaps = 6/259 (2%) Query: 3 HIPRKRFGQNFLTDDVVLHDIISSIAPAADDAMVEIGPGLAAMTELLLEQARHLHVVELD 62 H RKRFGQNFL DD V+H I+++I P DD +VEIGPGL A+T L+E+ L VVELD Sbjct: 12 HQARKRFGQNFLVDDGVIHAIVAAIDPQPDDVLVEIGPGLGALTVPLMERVPTLQVVELD 71 Query: 63 RDLVERLKKRFDPTRLTVHSADALKFDFASIPVPAGRKLRVVGNLPYNISSPLLFHLAEI 122 RDLV RL++RF +L VH+ DAL FDF ++ VP GR LR+VGNLPYNISSPLLFHL+ Sbjct: 72 RDLVARLQRRFG-DKLIVHAGDALAFDFGTLHVP-GRSLRIVGNLPYNISSPLLFHLSAF 129 Query: 123 APQVQDQHFMLQKEVVERMVAEPGSKVYGRLSVMLQWRYDMELLFVVPPTAFDPPPKVDS 182 A +V+DQHFMLQKEVV+RMVA PGSK + RLSVMLQ RY MEL+ VPP +F+PPPKVDS Sbjct: 130 ADRVRDQHFMLQKEVVDRMVAAPGSKAFSRLSVMLQVRYYMELVLEVPPGSFNPPPKVDS 189 Query: 183 AIVRMIPL---AQPMA-CEQALLEKVVTQAFSQRRKVIRNCLAGLFSEEELRQVGVDPQA 238 A+VRMIP P A + L VVT AFSQRRKV+RN L L + +G D Sbjct: 190 AVVRMIPWPADKSPYAPVDMRALGTVVTLAFSQRRKVLRNTLGSLREVIDFDALGFDLGR 249 Query: 239 RPETVPVQQFVALAQLLAA 257 R E VPV FVA+A L A Sbjct: 250 RAEEVPVADFVAVANALPA 268 >NMA0902 [J] COG0030 Dimethyladenosine transferase (rRNA methylation) NmA Neisseria meningitidis Z2491 Length = 259 Score = 273 bits (698), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 140/260 (53%), Positives = 183/260 (70%), Gaps = 6/260 (2%) Query: 2 KHIPRKRFGQNFLTDDVVLHDIISSIAPAADDAMVEIGPGLAAMTELLLEQARHLHVVEL 61 +H RKRFGQNFL D ++ DI++++ P ADD ++EIGPGLAA+TE L ++ LHVVE+ Sbjct: 3 EHKARKRFGQNFLQDTRIISDIVNAVRPQADDVVIEIGPGLAAITEPLAKKLNRLHVVEI 62 Query: 62 DRDLVERLKKRFDPTRLTVHSADALKFDFASIPVPAGRKLRVVGNLPYNISSPLLFHLAE 121 DRD+V RLK +L +H D L+FDF I AG+K ++VGNLPYNIS+PLLF LAE Sbjct: 63 DRDIVCRLKTLPFADKLVIHEGDVLQFDFNGI---AGKK-KIVGNLPYNISTPLLFKLAE 118 Query: 122 IAPQVQDQHFMLQKEVVERMVAEPGSKVYGRLSVMLQWRYDMELLFVVPPTAFDPPPKVD 181 +A V D HFMLQKEVV+RMVA P S YGRL VMLQ+ +DME+L VPP +FDP PKVD Sbjct: 119 VADDVVDMHFMLQKEVVDRMVAAPKSNDYGRLGVMLQYFFDMEMLIDVPPESFDPAPKVD 178 Query: 182 SAIVRMIPLAQPMACEQAL--LEKVVTQAFSQRRKVIRNCLAGLFSEEELRQVGVDPQAR 239 SA+VRMIP+ + K+V AF QRRK IRN L L +++L+ VG++PQ R Sbjct: 179 SAVVRMIPVKHRIGKADDFEHFAKLVKLAFHQRRKTIRNNLKELAGDDDLQAVGINPQDR 238 Query: 240 PETVPVQQFVALAQLLAARA 259 E + +++VAL+ LA +A Sbjct: 239 AEHIAPEKYVALSNYLAGKA 258 >NMB0697 [J] COG0030 Dimethyladenosine transferase (rRNA methylation) Nme Neisseria meningitidis MC58 Length = 259 Score = 273 bits (697), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 140/259 (54%), Positives = 182/259 (70%), Gaps = 6/259 (2%) Query: 2 KHIPRKRFGQNFLTDDVVLHDIISSIAPAADDAMVEIGPGLAAMTELLLEQARHLHVVEL 61 +H RKRFGQNFL D ++ DI++++ P ADD ++EIGPGLAA+TE L ++ LHVVE+ Sbjct: 3 EHKARKRFGQNFLQDTRIISDIVNAVRPQADDVVIEIGPGLAAITEPLAKKLNRLHVVEI 62 Query: 62 DRDLVERLKKRFDPTRLTVHSADALKFDFASIPVPAGRKLRVVGNLPYNISSPLLFHLAE 121 DRD+V RLK +L +H D L+FDF I AG+K ++VGNLPYNIS+PLLF LAE Sbjct: 63 DRDIVCRLKTLPFADKLVIHEGDVLQFDFNGI---AGKK-KIVGNLPYNISTPLLFKLAE 118 Query: 122 IAPQVQDQHFMLQKEVVERMVAEPGSKVYGRLSVMLQWRYDMELLFVVPPTAFDPPPKVD 181 +A V D HFMLQKEVVERMVA P S YGRL VMLQ+ +DME+L VPP +FDP PKVD Sbjct: 119 VADDVVDMHFMLQKEVVERMVAAPKSNDYGRLGVMLQYFFDMEMLIDVPPESFDPAPKVD 178 Query: 182 SAIVRMIPLAQPMACEQAL--LEKVVTQAFSQRRKVIRNCLAGLFSEEELRQVGVDPQAR 239 SA+VRMIP+ + K+V AF QRRK IRN L L +++L+ VG++PQ R Sbjct: 179 SAVVRMIPVKHRIGKADDFEHFAKLVKLAFHQRRKTIRNNLKELAGDDDLQAVGINPQDR 238 Query: 240 PETVPVQQFVALAQLLAAR 258 E + +++VAL+ LA + Sbjct: 239 AEHIAPEKYVALSNYLAGK 257 >PA0592 [J] COG0030 Dimethyladenosine transferase (rRNA methylation) Pae Pseudomonas aeruginosa Length = 268 Score = 263 bits (671), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 141/258 (54%), Positives = 179/258 (69%), Gaps = 4/258 (1%) Query: 2 KHIPRKRFGQNFLTDDVVLHDIISSIAPAADDAMVEIGPGLAAMTELLLEQARHLHVVEL 61 +H RKRFGQNFL D V+H I+ +I ++EIGPG A+TE LL L V+EL Sbjct: 6 QHRARKRFGQNFLHDAGVIHRILRAIHAREGQRLLEIGPGQGALTEGLLGSGARLDVIEL 65 Query: 62 DRDLVERLKKRFD-PTRLTVHSADALKFDFASIPVPAGRKLRVVGNLPYNISSPLLFHLA 120 D+DL+ LK +F +R ++H DALKFDFAS+ V +G KLRVVGNLPYNIS+PL+FHL Sbjct: 66 DQDLIPLLKLKFGLESRFSLHQGDALKFDFASL-VESGEKLRVVGNLPYNISTPLIFHLL 124 Query: 121 EIAPQVQDQHFMLQKEVVERMVAEPGSKVYGRLSVMLQWRYDMELLFVVPPTAFDPPPKV 180 E AP ++D HFMLQKEVVER+ A PG +GRLS+M+Q+ +E LF V P AF+PPPKV Sbjct: 125 EHAPVIEDMHFMLQKEVVERLAATPGGGDWGRLSIMVQYHCRVEHLFNVGPGAFNPPPKV 184 Query: 181 DSAIVRMIPLAQP--MACEQALLEKVVTQAFSQRRKVIRNCLAGLFSEEELRQVGVDPQA 238 DSAIVR+ P A+P A + LLE+VV +AF+QRRK +RN L L S E++ VDP Sbjct: 185 DSAIVRLTPFAEPPHPARDPKLLERVVREAFNQRRKTLRNTLKPLLSVEDIEAAEVDPTL 244 Query: 239 RPETVPVQQFVALAQLLA 256 RPE + + FV LA LA Sbjct: 245 RPEQLDLAAFVRLANQLA 262 >ksgA [J] COG0030 Dimethyladenosine transferase (rRNA methylation) Eco Escherichia coli K12 Length = 273 Score = 260 bits (664), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 134/260 (51%), Positives = 173/260 (66%), Gaps = 3/260 (1%) Query: 3 HIPRKRFGQNFLTDDVVLHDIISSIAPAADDAMVEIGPGLAAMTELLLEQARHLHVVELD 62 H+ RKRFGQNFL D V+ I+S+I P AMVEIGPGLAA+TE + E+ L V+ELD Sbjct: 9 HLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELD 68 Query: 63 RDLVERLKKR-FDPTRLTVHSADALKFDFASIPVPAGRKLRVVGNLPYNISSPLLFHLAE 121 RDL RL+ F +LT++ DA+ F+F + G+ LRV GNLPYNIS+PL+FHL Sbjct: 69 RDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFS 128 Query: 122 IAPQVQDQHFMLQKEVVERMVAEPGSKVYGRLSVMLQWRYDMELLFVVPPTAFDPPPKVD 181 + D HFMLQKEVV R+VA P SK YGRLSVM Q+ ++ + VPP+AF PPPKVD Sbjct: 129 YTDAIADMHFMLQKEVVNRLVAGPNSKAYGRLSVMAQYYCNVIPVLEVPPSAFTPPPKVD 188 Query: 182 SAIVRMIPLAQ-PMACEQA-LLEKVVTQAFSQRRKVIRNCLAGLFSEEELRQVGVDPQAR 239 SA+VR++P A P + +L ++ T+AF+QRRK IRN L LFS E L +G+DP R Sbjct: 189 SAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTGMGIDPAMR 248 Query: 240 PETVPVQQFVALAQLLAARA 259 E + V Q+ +A LA A Sbjct: 249 AENISVAQYCQMANYLAENA 268